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Pancreatic endometrial cyst mimics mucinous cystic neoplasm of the pancreas

World Journal of Gastroenterology 2017年第6期23卷 1113-1118页

作者： Michael A Mederos Nicole Villafane sadhna dhingra Carlos Farinas Amy Mc Elhany William E Fisher George Van Buren II Department of General Surgery Baylor College of Medicine Department of Pathology Baylor College of Medicine Department of Radiology Baylor College of Medicine

Pancreatic cysts include a variety of benign, premalignant, and malignant lesions. Endometrial cysts in the pancreas are exceedingly rare lesions that are difficult to diagnose pre-operatively. This report describes the findings in a 43-year-old patient with a recent episode of acute pancreatitis who presented with a large cyst in the tail of the pancreas. Imaging demonstrated a loculated pancreatic cyst, and cyst fluid aspiration revealed an elevated amylase and carcinoembryonic antigen. The patient experienced an interval worsening of abdominal pain, fatigue, diarrhea, and a 15-pound weight loss 3 mo after the initial episode of pancreatitis. With concern for a possible pre-malignant lesion, the patient underwent a laparoscopic distal pancreatectomy with splenectomy, which revealed a 16cm×12cm×4cm lesion. Final histopathology was consistent with an intra-pancreatic endometrial cyst. Here we discuss the overlapping imaging and laboratory features of pancreatic endometrial cysts and mucinous cystic neoplasms of the pancreas.

关键词：胰腺的包囊胰腺的子宫内膜的包囊子宫内膜增生胰的 Mucinous 膀胱的瘤远侧的 pancreatectomy

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Liver pathology of hepatitis C,beyond grading and stagingof the disease

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World Journal of Gastroenterology 2016年第4期22卷 1357-1366页

作者： sadhna dhingra Stephen C Ward Swan N Thung Department of Pathology and Laboratory Medicine University of Texas Health Science Center at HoustonHoustonTX 77030United States Division of Hepatopathology Department of PathologyThe Mount Sinai Medical CenterNew YorkNY 10029United States

Liver biopsy evaluation plays a critical role in management of patients with viral hepatitis C. In patients with acute viral hepatitis, a liver biopsy, though uncommonly performed, helps to rule out other nonviral causes of deranged liver function. In chronic viral hepatitis C, it is considered the gold standard in assessment of the degree of necroinflammation and the stage of fibrosis, to help guide treatment and determine prognosis. It also helps rule out any concomitant diseases such as steatohepatitis, hemochromatosis or others. In patients with chronic progressive liver disease with cirrhosis and dominant nodules, a targeted liver biopsy is helpful in differentiating a regenerative nodule from dysplastic nodule or hepatocellular carcinoma. In the setting of transplantation, the liver biopsy helps distinguish recurrent hepatitis C from acute rejection and also is invaluable in the diagnosis of fibrosing cholestatic hepatitis, a rare variant of recurrent hepatitis C. This comprehensive review discusses the entire spectrum of pathologic findings in the course of hepatitis C infection.

关键词： Hepatitis C Liver pathology Biopsy Grading Staging Neoplasia

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