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Asian Journal of Andrology 2005年第2期7卷 217-220,页

作者： Takuya Akashi Hideki Fuse Yasuo Kojima Mikiko Hayashi sachiko honda Department of Urology Faculty of MedicineToyama Medical and Pharmaceutical UniversityToyamaJapan Department of Obsterics and Gynecology Toyama Prefectural Central HospitalToyamaJapan Toyama Institute of Health ToyamaJapan

Aim:To report a birth after intracytoplasmic sperm injection (ICSI) of ejaculated spermatozoa from a man with mosaic Klinefelter's syndrome detected by fluorescence in situ hybridization (FISH) ***:A 35-year- old man with a normal appearance consulted our hospital because of sterility over a 5-year *** analysis showed low-incidence mosaic Klinefelter's *** FISH,96 % hyperploidy of the lymphocytes was *** examined the sex chromosome of the ejaculated *** FISH,we examined 200 ejacu- lated spermatozoa and no hyperploidy was ***:The 33-year-old female partner of the male patient underwent an uncomplicated controlled ovarian hyperstimulation sequence using a combined recombinant-follicle stimulating hormone (rec-FSH) + human menopausal gonadotrophin (hMG) protocol,following late luteal phase pituitary down *** culminated in the retrieval of seven oocytes,six of which were fertilized with ICSI. One ICSI attempt led to clinical pregnancy with a healthy baby ***:We report a male patient with low- incidence mosaic Klinefelter's syndrome whose ejaculated spermatozoa were identified as being haploid by FISH before ICSI,leading to the successful pregnancy of his wife and the birth of a healthy baby girl.

关键词： Klinefelter's syndrome intracytoplasmic sperm injection fluorescence in situ hybridization

中日高中生汉语教材比较研究 ——以《高校生からの中国語》（从高中学起的汉语）与《跟我学汉语》（日语版）为例

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中日高中生汉语教材比较研究 ——以《高校生からの中国語》（从...

作者：本夛美季（honda MIKI）华东师范大学

学位级别：硕士

日本具有悠久的学习和使用汉语的历史,并且一直致力于推广汉语教育,这一点与其他国家相比尤其特殊。自中国汉朝开始,日本就着力推进汉语教育,而明治时期出版的教材《亚细亚言语集》,是日本第一部北京官方语言的教材,由日本学者广部精编... 详细信息

日本具有悠久的学习和使用汉语的历史,并且一直致力于推广汉语教育,这一点与其他国家相比尤其特殊。自中国汉朝开始,日本就着力推进汉语教育,而明治时期出版的教材《亚细亚言语集》,是日本第一部北京官方语言的教材,由日本学者广部精编写,它对日本汉语教育的发展起到了极其重要的作用。中国的改革开放在日本也快速掀起了一股“汉语热”。尽管日本本土出版了众多版本的汉语教材,但是缺乏具有权威性的汉语教材,而中国编辑出版的对日汉语教材在针对性方面又值得商榷。目前,针对对日汉语教材的比较研究寥寥无几,各种版本的日本汉语教材各自的特色与优缺点无法体现。因此有必要对这些教材进行比较研究,为编写具有针对性的对日汉语教材提供依据,以满足如此众多汉语学习者,特别是青少年汉语学习者的需求。本文基于实用性、针对性、趣味性、丰富性等教材编写理论,利用文献资料法、数据统计法与比较归纳法等方法,从语音、词汇、语法、汉字、练习、话题、文化、插图和课文等多个方面入手,对两套具有代表性的对日汉语教材《高校生からの中国語》(从高中学起的汉语)与《跟我学汉语》(日语版)进行全面的量化比较研究,揭示两套教材在选材、编写理念、文化内涵、侧重点等方面的异同,获得关于两套教材内容逐项量化统计与比较分析结果,佐证两套教材存在的优缺点,指出两部教材的互补性,并提出了相应的建议。希望本文的研究结果将有助于教材编写者,结合日本文化背景以及日本人的思维习惯,编写具有针对性的高质量的初级对日汉语教材。

关键词：《高校生からの中国語》(从高中学起的汉语) 《跟我学汉语》(日语版) 国际中文教育初级汉语教材教材对比

On the Live Coloration and Partial Mitochondrial DNA Sequences in the Topotypic Population of Goniurosaurus kuroiwae orientalis(Squamata: Eublepharidae), with Description of a New Subspecies from Tokashikijima Island, Ryukyu Archipelago, Japan

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Asian Herpetological Research 2017年第2期18卷 96-107页

作者： Masanao honda Hidetoshi OTA Faculty of Life and Environmental Sciences University of Tsukuba Institute of Natural and Environmental Sciences University of Hyogo and Museum of Nature and Human Activities

Careful investigations of live coloration and other characters in the eublepharid gecko Goniurosaurus kuroiwae orientalis from Tonakijima Island, the type locality of the subspecies in the Central Ryukyus, Japan, revealed its slight but consistent external differences from the consubspecific Tokashikijima population, whose phylogenetically divergent status against the former had been strongly suggested in a previous molecular study. A new subspecies, Goniurosaurus kuroiwae sengokui subsp. nov., is thus described for the Tokashikijima population. In life, Goniurosaurus k. sengokui subsp. nov. can be discriminated from G. k. orientalis in showing tint of reddish or pinkish, instead of yellowish, coloration in dorsal body pattern, and also usually darker and more or less reddish, instead of yellowish or grayish, iris in both adults and juveniles. Recalculation of sequence data at hand with relevant Gen Bank data confirmed substantial sequence divergences of G. k. sengokui from all other congeneric taxa of the Ryukyus described so far.

关键词： Eublepharidae Goniurosaurus morphology taxonomy Ryukyu Archipelago

Correlation between the molecular structure and transcis isomerization characteristics of azobenzenes

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Science China Chemistry 2011年第12期54卷 1955-1961页

作者： HAN Mina honda Takumu Department of Chemistry and Department of Electronic Chemistry Tokyo Institute of Technology

Photochemical and thermal isomerization of various azobenzenes was systematically investigated to understand the correlation between the molecular structure and trans → cis isomerization characteristics of azobenzenes. A blue shift in π-π absorption band of ortho-alkylated azobenzenes （1o and 2o） was observed together with a reduction in molar extinction coefficient （e） in comparison with both meta-alkylated azobenzenes （4m and 5m） and 7p lacking the meta and ortho substituents. For orthoalkylated azobenzene, photochemical trans-to-cis isomerization and thermal back cis-to-trans isomerization in solution oc- curred slowly when compared with 4m, 5m and 7p. The half-life time of the cis form of 20 was found to be 380 h, which is about 8-50 times longer than those of comparable 4m, 5m （43-13 h） and 7p （7 h）. Furthermore, comparison of the molecular structure and isomerization characteristics of azobenzene thiol （20 and 5m） self-assembled monolayers on flat gold surfaces indicates that the trans-to-cis photoconversion in monolayer systems is influenced by steric hindrance and strong intermoleculax interaction between azobenzene units.

关键词： azobenzene isomerization lifetime of cis form molecular structure

Sharp Growth Theorems and Coefficient Bounds for Starlike Mappings in Several Complex Variables

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Chinese Annals of Mathematics,Series B 2008年第4期29卷 353-368页

作者： Hidetaka HAMADA Tatsuhiro honda Faculty of Engineering Kyushu Sangyo University Department of Architectural Engineering Hiroshima Institute of Technology

Let B be the unit ball in a complex Banach space. Let S^＊k＋1（B） be the family of normalized starlike mappings f on B such that z = 0 is a zero of order k ＋ 1 of f（z） - z. The authors obtain sharp growth and cov... 详细信息

关键词： Sharp coefficient bound Sharp covering theorem Sharp growth theorem Starlike mapping Zero of order k

Semi-polar GaN LEDs on Si substrate

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Science China(Technological Sciences) 2011年第1期54卷 38-41页

作者： Nobuhiko SAWAKI Yoshio honda Department of Electrical and Electronic Engineering Aichi Institute of Technology Department of Electronics and Akasaki Research Center Nagoya University

Growth of semi-polar （1-101）GaN has been attempted on a patterned （001） silicon substrate adopting selective area MOVPE. The growth was initiated on （111） facets of the Si, which had been prepared by anisotropy etching in a KOH solution. A uni- form semi-polar layer was achieved by coalescence of stripes. Since the growth was performed on facets, the surface was atomically fiat in AFM surface analyses. By using a high temperature grown A1N nucleation layer, we achieved low threading dislocation density at the top most surface. Moreover, by tilting the c-axis of the GaN on the Si substrate, the effect of the thermal expansion coefficient mismatch was much reduced. As the result, we achieved a crack free （1-101）GaN template on （001）Si. On the thus prepared （1-101）GaN, a GalnN/GaN LED was fabricated, which showed excellent performance with weak quantum confined Stark effect.

关键词： GaN selective epitaxy semi-polar GaN MOVPE LED

A note on the collapsing geometry of hyperkahler four manifolds

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Science China Mathematics 2019年第11期62卷 2195-2210页

作者： Shouhei honda Song Sun Ruobing Zhang Mathematical Institute Tohoku UniversitySendai 980-8578Japan Department of Mathematics University of California at BerkeleyBerkeleyCA 94720USA Department of Mathematics Stony Brook UniversityStony BrookNY 11790USA

We make some observations concerning the one-dimensional collapsing geometry of four-dimensional hyperk?hler metrics.

关键词： hyperkahler metrics collapsing K3 manifold

Prediction of Photosynthetic Carbon Assimilation Rate of Individual Rice Leaves under Changes in Light Environment Using BLSTM-Augmented LSTM

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Computer Modeling in Engineering & Sciences 2022年第12期133卷 557-577页

作者： Masayuki honda Kenichi Tatsumi Masaki Nakagawa Graduate School of Bio-Applications and Systems Engineering Tokyo University of Agriculture and TechnologyKoganei City184-8588Japan Institute of Agriculture Tokyo University of Agriculture and TechnologyFuchu City183-0054Japan Institute of Engineering Tokyo University of Agriculture and TechnologyKoganei City184-8588Japan

A model to predict photosynthetic carbon assimilation rate(A)with high accuracy is important for forecasting crop yield and *** short-term memory(LSTM),a neural network suitable for time-series data,enables prediction with high accuracy but requires mesophyll *** addition,for practical use,it is desirable to have a technique that can predict A from easily available *** this study,we propose a BLSTM augmented LSTM(BALSTM)model,which utilizes bi-directional LSTM(BLSTM)to indirectly reproduce the mesophyll variables required for *** most significant feature of the proposed model is that its hybrid architecture uses only three relatively easy-to-collect external environmental variables—photosynthetic photon flux density(Q_(in)),ambient CO_(2) concentration(C_(a)),and temperature(T_(air))—to generate mesophyll CO_(2) concentration(C_(i))and stomatal conductance to water vapor(g_(sw))as intermediate ***,A is predicted by applying the obtained intermediate outputs to the learning ***,in this study,1)BALSTM(Q_(in),C_(a),T_(air))had a significantly higher A prediction accuracy than LSTM(Q_(in),C_(a),T_(air))in case of using only Q_(in),C_(a),and T_(air);2)BALSTMC_(i),g_(sw),which had C_(i) and g_(sw) as intermediate products,had the highest A prediction accuracy compared with other candidates;and 3)for samples where LSTM(Q_(in),C_(a),T_(air))had poor prediction accuracy,BALSTMC_(i),g_(sw)(Q_(in),C_(a),T_(air))clearly improved the ***,it was found that incorrect predictions may be formed when certain factors are not reflected in the data(e.g.,timing,cultivar,and growth stage)or when the training data distribution that accounts for these factors differs from the predicted data ***,a robust model should be constructed in the future to improve the prediction accuracy of A by conducting gasexchange measurements(including a wide range of external environmental values)and by increasing the

关键词： Hybrid prediction model assimilation rate leaf internal variables recurrent neural network fluctuating light environments rice

Treatment of postherpetic neuralgia by bone marrow aspirate injection:A case report

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World Journal of Clinical Cases 2023年第15期11卷 3619-3624页

作者： Takahiro honda Pazili Regenerative Medicine Department of Cell Therapy Japan Tokyo Stem Cell Transplant Research InstituteTokyo 104-0061Japan

BACKGROUND Postherpetic neuralgia(PHN)is the most frequent and a difficult-to-treat complication of herpes zoster(HZ).Its symptoms include allodynia,hyperalgesia,burning,and an electric shock-like sensation stemming from the hyperexcitability of damaged neurons and varicella-zoster virus-mediated inflammatory tissue ***-related PHN has an incidence of 5%–30%,and in some patients,the pain is intolerable and can lead to insomnia or *** many cases,the pain is resistant to pain-relieving drugs,necessitating radical *** SUMMARY We present the case of a patient with PHN whose pain was not cured by conventional treatments,such as analgesics,block injections,or Chinese medicines,but by bone marrow aspirate concentrate(BMAC)injection containing bone marrow mesenchymal stem *** has already been used for joint ***,this is the first report on its use for PHN *** This report reveals that bone marrow extract can be a radical therapy for PHN.

关键词： Bone marrow aspirate concentrate Postherpetic neuralgia Herpes zoster Bone marrow mesenchymal stem cells Pain syndrome Case report

Mechanisms of gastrointestinal barrier dysfunction in COVID-19 patients

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World Journal of Gastroenterology 2023年第15期29卷 2283-2293页

作者： Weijie Xue Masaki honda Taizo Hibi Department of Transplantation and Pediatric Surgery Kumamoto UniversityKumamoto 860-8556Japan

Coronavirus disease 2019(COVID-19)caused by the novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has become a major global public health event,resulting in a significant social and economic *** COVID-19 was initially characterized as an upper respiratory and pulmonary infection,recent evidence suggests that it is a complex disease including gastrointestinal symptoms,such as diarrhea,nausea,and ***,it remains unclear whether the gastrointestinal symptoms are caused by direct infection of the gastrointestinal tract by SARS-CoV-2 or are the result of systemic immune activation and subsequent dysregulation of homeostatic *** review provides a brief overview of the mechanisms by which SARS-CoV-2 disrupts the integrity of the gastrointestinal barrier including the mechanical barrier,chemical barrier,microbial barrier,and immune barrier.

关键词： Gastrointestinal barrier dysfunction SARS-CoV-2 COVID-19 Angiotensinconverting enzyme 2 Microbiome Immune cells