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Gastro Intestinal Stromal Tumor: State of the Art through Our Experience of 64 Cases and a Literature Review

Journal of Cancer Therapy 2020年第5期11卷 265-275页

作者： saad slaiki Hicham El Bouhaddouti Abdelmalek Ousadden Khalid Ait Taleb El Bachir Benjelloun Visceral Surgery Department CHU Hassan II Fes Morocco

Gastrointestinal stromal tumors are rare. They are a subject of controversy. We have reported 64 cases of gastrointestinal stromal tumor diagnosed in the surgery department of CHU Hassan II of FES between January 2014 and December 2018. The study involved 64 patients (34 men and 30 women) with an average age of 56. The circumstances of findings were dominated by abdominal pain (48 cases), vomiting 16 case followed by transit disorder with 9 cases. The tumor locations were mainly the stomach (n = 31), the small intestine (n = 28), the duodenum (n = 3), and the colon (n = 2). Ultrasound, endoscopy and CT were the main additional tests to detect tumor syndrome. 55 patients were treated by complete surgical excision. Tumor size ranged from 4cm to 18cm. Histologically, the spindle cell type was predominant in 88.91% of cases;epithelioid type was present in 7.81% of cases, while the mixed type was found in 3.6%. The analysis of the expression of CD 117 marker was present in 95.31%, while immunostaining with this marker returned negative in 3 cases;i.e. 5% whose c-kit was positive. Imatinib was indicated in 44 patients (63.60%), with 9 indications for metastatic tumor. As a neoadjuvant, imatinib was indicated in 5 patients, with remission in 28 patients (50.9%), stabilization in 4 patients (7.2%), 2 cases of tumor recurrence and 7 cases of death.

关键词： Stromal Tumor Imatinib Surgery GIST

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Post Traumatic Diaphragmatic Hernia Revealing a Colonic Tumor

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Open Journal of Thoracic Surgery 2016年第3期6卷 13-17页

作者： Mohammed Elkehal Sani Rabiou Boubacar Efared saad slaiki Hicham Elbouhadouti Yassine Ouadnouni Nawal Hammas Taoufiq Harmouch Mohamed Smahi Department of Visceral Surgery Hassan II University Hospital Fez Morocco Department of Thoracic Surgery Hassan II University Hospital Fez Morocco Department of Cyto-Pathology Hassan II University Hospital Fez Morocco Faculty of Medicine and Pharmacy Sidi Mohamed Benabdellah University Fez Morocco

Post traumatic diaphragmatic injuries have long been known. However their varied clinical, expressions lead to difficulties which cause its delay. The occurrence of herniation of hollow viscera in the thoracic cavity followed by its necrosis or perforation, is a delayed complication, a rare entity with a poor prognosis. The discovery of a colonic tumor in a diaphragmatic hernia is an exceptional clinical circumstance. Here we report the case of a patient with a complicated diaphragmatic hernia, whose symptoms are precipitated by the presence of a colon stenosing tumor. The management consisted of an exclusive laparotomy had allowed dealing in one surgical intervention with both the abdominal and thoracic injuries.

关键词： Diaphragmatic Hernia Gastrointestinal Tumor Surgery

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