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Neurophysics Assessment of the Muscle Bioenergy Generated by Transcranial Magnetic Stimulation

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Research 2019年第1期2019卷 1077-1085页

作者： Fidias E.Leon-sarmiento Alexander Gonzalez-Castaño Carlos V.Rizzo-Sierra Juan Aceros Daniel S.Leon-Ariza Juan S.Leon-Ariza Diddier G.Prada William Bara-Jimenez Zeng Y.Wang Smell and Taste Center Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPAUSA Human Motor Control Section NINDSNational Institutes of HealthBethesdaMDUSA Mediciencias Research Group LouisvilleKYUSA Universidad Internacional de la Rioja Spain Neurophysics Unit Corporacion Universitaria Minuto de Dios-UNIMINUTOColombia Charity Association for Person Centered Medicine Moral EntityItaly School of Engineering University of North FloridaJacksonvilleFLUSA Faculty of Health Sciences Santander UniversityUDESColombia department of Neurosurgery Johns Hopkins UniversityBaltimoreMAUSA Harvard T.H.Chan School of Public Health Harvard UniversityBostonMAUSA Unidad de Investigacion Biomedica en Cancer Instituto Nacional de CancerMexico DFMexico Neuromuscular Division Department of NeurologyUniversity of LouisvilleLouisvilleKYUSA

Te content of the rectifed motor evoked potential(MEP)induced by transcranial magnetic stimulation(TMS)has ambiguously been assessed without the precision that energy calculation *** fact has misled data interpretation and misguided biomedical *** defnitively fll the gap that exits in the neurophysics processing of these signals,we computed,in Walls(̂�),the bioenergy within the rectifed MEP recorded from the human frst digitorum index(FDI)muscle at rest and under isometric *** also gauged the biowork exerted by this *** we show that bioenergy and biowork can accurately and successfully be assessed,validated,and determined in̂�from MEP signals induced by TMS,regardless of knowing the mathematical expression of the function of the *** novel neurophysics approach represents a dramatic paradigm shif in analysis and interpretation of the content of the MEP and will give a true meaning to the content of rectifed ***,this innovative approach allowed unveiling that women exerted more bioenergy than men at the magnetic stimulations used in this *** of conclusions drawn from studies published elsewhere assessing rectifed EMG signals that have used ambiguous units is strongly recommended.

关键词： stimulation gauge allowed

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谎言重复千遍也不会成为真理

友声 2021年第2期 26-26页

作者：胡安·德·迪奥斯·帕拉拉丁美洲人权协会中国-拉丁美洲加勒比旅游、科技、文化交流促进联盟

当拉斐尔·莱姆金1944年首次提出"种族灭绝"这一说法时,一定想不到这个概念在人类历史上将会变得多么重要。莱姆金将种族灭绝定义为旨在全部或部分地消灭一个国家、民族、种族或宗教群体的行为。如果将他的定义稍作泛化,种族灭绝可以被... 详细信息

当拉斐尔·莱姆金1944年首次提出"种族灭绝"这一说法时,一定想不到这个概念在人类历史上将会变得多么重要。莱姆金将种族灭绝定义为旨在全部或部分地消灭一个国家、民族、种族或宗教群体的行为。如果将他的定义稍作泛化,种族灭绝可以被认为是"对于人类族群生存权的剥夺"。1948年联合国大会通过的《防止及惩治灭绝种族罪公约》第二条将种族灭绝行为定义为"蓄意全部或局部消灭某一民族、人种、种族或宗教团体"的所有行为。

关键词：种族灭绝灭绝种族罪宗教团体生存权拉斐尔联合国大会行为定义宗教群体

The Impact of an Educational Intervention on Inflammatory Bowel Disease for Nurses in Brazil

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open Journal of Nursing 2020年第12期10卷 1178-1185页

作者： Jaqueline Ribeiro de Barros Adriana Rivera-Sequeiros Julio Pinheiro Baima Fernanda Lofiego Renosto Rogerio saad-Hossne Ligia Yukie sassaki department of Internal Medicine Medical School S&#227 o Paulo State University (UNESP) Botucatu Brazil department of Internal Medicine San Juan de Dios del Aljarafe Hospital Seville Spain department of Surgery Medical School S&#227 o Paulo State University (UNESP) Botucatu Brazil

Background: The inflammatory bowel disease nurse plays a key role in the multidisciplinary team. The aim of the study was to evaluate the inflammatory bowel disease knowledge before and after the educational intervent... 详细信息

ong>Background:ong> The inflammatory bowel disease nurse plays a key role in the multidisciplinary team. The aim of the study was to evaluate the inflammatory bowel disease knowledge before and after the educational intervention with nurses. ong>Methods:ong> A cross-sectional, descriptive and comparative study was performed from June to August 2016. The sample consisted of 26 nurses from the nursing staff of a public university hospital in São Paulo State, Brazil. The study was divided into three phases: pre-educational intervention, educational intervention and post-educational intervention (test application). A p-value onsidered to indicate statistically significance. ong>Results:ong> The study included 26 general nurses with an average of 9.20 ± 5.78 years of experience. There was an increase in safety in administering biological therapy after the course (from 33.34% to 78.26%), and an increase in knowledge about the main inflammatory bowel disease symptoms (64.29% vs 96.30%, p = 0.0224), and about infliximab infusion (35.71% vs 74.07%, p = 0.0404). ong>Conclusion:ong> The educational intervention effectively contributed to the increase of knowledge of the nursing staff.

关键词： Inflammatory Bowel Diseases Knowledge Nursing Education Nurses Continuing Education

Gold Mining and Mercury Bioaccumulation in a Floodplain Lake and Main Channel of the Tambopata River, Perú

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Journal of Environmental Protection 2013年第1期4卷 51-60页

作者： Katherine A. Roach Nicolas F. Jacobsen Christine V. Fiorello Amanda Stronza Kirk o. Winemiller department of Recreation Park and Tourism Sciences Texas A&M University College Station USA department of Wildlife and Fisheries Sciences Texas A&M University College Station USA Wildlife Health Center School of Veterinary Medicine University of California Davis USA

Contamination of water bodies by inorganic mercury (Hg[II]) used in placer mining of gold deposits in the Madre de dios department, Perú, contributes to the bioaccumulation of methylmercury (MeHg) in fish tissue. We measured MeHg and total Hg (THg) concentrations (mg/kg wet weight [ww] tissue) of thirteen fish species from the Tambopata River, Perú, and the connected oxbow lake Tres Chimbadas. We also used stable isotope analysis (δ15N and δ13C) to estimate trophic positions of fishes. Average MeHg concentrations of fish species ranged from 0.042 mg/kg ww (satanoperca jurupari) to 0.463 mg/kg ww (Hoplias malabaricus) in the main channel and from 0.090 mg/kg ww (Parauchenipterus sp.) to 1.282 mg/kg ww (Pimelodina flavipinnis) in the lake. Spearman rank correlation indicated that trophic position had no influence on MeHg concentrations of species in the main channel, but in the lake, trophic positions of species were positively associated with MeHg. Migrations of the pimelodid catfish surveyed from the main channel are well documented. Because little gold mining occurs at our study site, fishes from the main channel may be bioaccumulating MeHg from areas where mining is widespread. Fish species that reside in the lake are relatively sedentary and migration is limited by the brief period of floodplain inundation and the long, narrow corridor that connects the lake to the main channel;lake sediments are therefore the likely source for MeHg bioaccumulation. Five out of the eight fish species surveyed from the main channel and two out of the five species from the lake had MeHg levels higher than United States Environmental Protection Agency fish tissue criterion for human consumption.

关键词： Fishes Giant otter Gold Mining Mercury Methylmercury Perú

Metabolic Syndrome and Perioperative Complications during Scheduled Surgeries with Spinal Anesthesia

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open Journal of Anesthesiology 2014年第7期4卷 167-176页

作者： José Pomares Gustavo Mora-García Roberto Palomino Yéssika de León Claudio Gómez-Alegría Doris Gómez-Camargo Anesthesiology and Reanimation department Faculty of Medicine University of Cartagena Cartagena de Indias Colombia Faculty of Medicine University of Cartagena Cartagena de Indias Colombia Pharmacy department Faculty of Sciences National University of Colombia Bogotá Colombia Tropical Medicine Doctorate Program Faculty of Medicine University of Cartagena Cartagena de Indias Colombia

Background: Metabolic syndrome (MS) is a constellation of factors associated with increased risk of developing cardiovascular diseases and Diabetes Mellitus. despite of the many studies related to MS, little is known about its impact on scenarios such as surgical anesthesia. objective: To examine the correlation between demographic and metabolic variables with the occurrence of perioperative complications in patients with MS undergoing scheduled surgeries using a spinal anesthesia technique in the surgery department at the University Clinic san Juan de dios in Cartagena de Indias, Colombia. Methods: observational, analytical, cross-sectional, single-center study of 150 subjects with MS and 150 control subjects. Perioperative complications, socio-demographic, hemodynamic and respiratory variables were registered. Groups were compared using t test, Fisher’s exact test or Chi-square, as appropriate. We applied a logistic multiple regression model, adjusted by backward stepwise at 0.25 and forward at 0.05, to find possible incompatible associations. p value onsidered significant. Results: There were significant differences between groups in age, American Society of Anesthesiologists physical status classification, frequency of diseases associated to MS and perioperative complications. There were no cases of mortality among patients. There was statistically significant difference between the two groups for intraoperative hypotension and hypertension with p values of ong postoperative complications there was statistically significant difference in pain (13.3% vs 5.3% in patients without MS) and nausea and/or postoperative vomiting (8% vs 2% in patients without MS) with a p value of 0.027 and 0.015 (by Fisher) respectively. Conclusions: Metabolic abnormalities in MS are a risk factor for developing complications in the perioperative period of patients scheduled for surgeries using the subarachnoid anesthesia technique. Accordingly, it is ap

关键词： Metabolic Syndrome X Insulin Resistance Spinal Anesthesia Abdominal obesity Perioperative Period

病态肥胖外科治疗术前对非酒精性脂肪性肝炎的检测:声脉冲辐射力成像技术的初步研究

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国际医学放射学杂志 2013年第1期 90-90页

作者： F.Guzmán-Aroca M.D.Frutos-Bernal A.Bas J.A.Luján-Mompeán M.Reus J.de dios Berná-Serna 程悦 department of of Radiology Virgen de la Arrixaca University Hospital30120 El PalmarMurciaSpain

目的在肥胖症治疗术前,采用声脉冲辐射力成像(ARFI)通过测定剪切波速度(SWV)技术,评价鉴别非酒精性脂肪肝(NAFLD)与非酒精性脂肪性肝炎(NASH)的能力。方法 32例肥胖症病人术前进行ARFI和常规超声检查。以肝脏活检结果为标准,并与ARFI和... 详细信息

目的在肥胖症治疗术前,采用声脉冲辐射力成像(ARFI)通过测定剪切波速度(SWV)技术,评价鉴别非酒精性脂肪肝(NAFLD)与非酒精性脂肪性肝炎(NASH)的能力。方法 32例肥胖症病人术前进行ARFI和常规超声检查。以肝脏活检结果为标准,并与ARFI和超声结果进行比较。根据组织学结果将病人分为3组:A组,单纯脂肪变性;B组,炎性改变;C组,纤维化。结果 SWV值的中位数为(1.57±0.79)m/s。所有病人的组织病理学检查均发现存在肝脏异常改变病变(100%),包括实验室检查正常者。A、B、C3组间的SWV值存在统计学差异,分别为(1.34±0.90)m/s、(1.55±0.79)m/s和(1.86±0.75)m/s(P<0.001)。鉴别NAFLD与NASH或纤维化的Az值为0.899(最佳界限值1.3m/s,敏感度85%,特异度83.3%)。结论在无症状的肥胖症病人中,ARFI技术是鉴别NAFLD与NASH的有效诊断工具。

关键词：非酒精性脂肪性肝肥胖症病人肥胖病 NAFLD 术前

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盾叶薯蓣中甾体皂苷的分离与结构鉴定

中草药 2008年第2期39卷 165-167页

作者：程娟胡长鹰庞自洁徐德平江南大学食品学院江苏无锡214122 暨南大学食品科学与工程系广东广州510520 江苏省、中国科学院植物研究所江苏南京210014

目的对盾叶薯蓣进行化学成分研究。方法利用反相色谱技术分离盾叶薯蓣水相部分中的化学成分,用1H-NMR、13C-NMR、135dePT、HMQC和HMBC等方法鉴定其结构。结果从新鲜的盾叶薯蓣根茎分得3个甾体皂苷,分别鉴定为薯蓣皂苷元-3-o-β-D-吡喃... 详细信息

目的对盾叶薯蓣进行化学成分研究。方法利用反相色谱技术分离盾叶薯蓣水相部分中的化学成分,用1H-NMR、13C-NMR、135dePT、HMQC和HMBC等方法鉴定其结构。结果从新鲜的盾叶薯蓣根茎分得3个甾体皂苷,分别鉴定为薯蓣皂苷元-3-o-β-D-吡喃葡萄糖基(1→3)-β-D-吡喃葡萄糖基(1→4)-[α-L-吡喃鼠李糖基(1→2 )]-β-D-吡喃葡萄糖苷(Ⅰ)、(25R)-26-o-β-D-吡喃葡萄糖基-呋甾烷-5-烯-3β,22ζ-二醇-3-o-β-D-吡喃葡萄糖基(1→3)-β-D-吡喃葡萄糖基(1→4)-[α-L-吡喃鼠李糖基(1→2)]-β-D-吡喃葡萄糖苷(Ⅱ)、(25R)-26-o-β-D-吡喃葡萄糖基-呋甾烷-5-烯-3β,22ζ-二醇-7-羰基-3-o-β-D-吡喃葡萄糖基(1→3)-β-D-吡喃葡萄糖基(1→4)-[α-L-吡喃鼠李糖基(1→2)]-β-D-吡喃葡萄糖苷(Ⅲ)。结论化合物Ⅲ为一新甾体皂苷,命名为盾叶薯蓣皂苷H(zingiberenin H)。

关键词：盾叶薯蓣呋甾烷皂苷甾体皂苷盾叶薯蓣皂苷H

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增塑剂对EPDM绝热层材料性能的影响

特种橡胶制品 2002年第5期23卷 9-11页

作者：邹德荣上海航天技术研究院第806研究所浙江湖州313002

选择了部分酯类有机化合物 (癸二酸二异辛酯、邻苯二甲酸二丁酯、磷酸三苯酯 )作为EPDM绝热层材料配方的增塑剂 ,测试了配方的力学性能、粘接性能和加速老化性能。结果表明 ,癸二酸二异辛酯大量使用后 ,EPDM绝热层材料配方的力学性能保... 详细信息

选择了部分酯类有机化合物 (癸二酸二异辛酯、邻苯二甲酸二丁酯、磷酸三苯酯 )作为EPDM绝热层材料配方的增塑剂 ,测试了配方的力学性能、粘接性能和加速老化性能。结果表明 ,癸二酸二异辛酯大量使用后 ,EPDM绝热层材料配方的力学性能保持稳定 ,邻苯二甲酸二丁酯、磷酸三苯酯大量使用后力学性能降低 ,当癸二酸二异辛酯含量在 1 0份以下时 ,EPDM绝热层的各项性能稳定。癸二酸二异辛酯是适用于EPDM绝热层材料配方的增塑剂。

关键词：增塑剂 EPDM 绝热层材料性能影响三元乙丙橡胶

Hepatoprotective effect of Geranium schiedeanum against ethanol toxicity during liver regeneration

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World Journal of Gastroenterology 2015年第25期21卷 7718-7729页

作者： Eduardo Madrigal-santillán Mirandeli Bautista Juan A Gayosso-de-Lucio Yadira Reyes-Rosales Araceli Posadas-Mondragón ángel Morales-González Marvin A Soriano-Ursúa Jazmín García-Machorro Eduardo Madrigal-Bujaidar Iselaálvarez-González JoséA Morales-González Laboratorio de Medicina de Conservación Escuela Superior de MedicinaInstituto Politécnico NacionalPlan de San Luis y Díaz MirónMéxico DF 11340México área Académica de Farmacia ICSaUniversidad Autónoma del Estado de HidalgoPachuca de Sotoestado de HidalgoCP 42000México Escuela Superior de Cómputo Instituto Politécnico NacionalAv.Juan de Dios Bátiz s/n esquina Miguel Othón de MendizabalUnidad Profesional Adolfo López Mateos departamento de Fisiología Escuela Superior de MedicinaInstituto Politécnico NacionalPlan de San Luis y Díaz MirónColonia Casco de Santo TomasDel.Miguel HidalgoMéxico DF 11340México Laboratorio de Genética Escuela Nacional de Ciencias BiológicasInstituto Politécnico NacionalAv.Wilfrido MassieuUnidad A.López MateosZacatencoMéxico DF 07700México

AIM: To evaluate the effect of an extract of Geranium schiedeanum(Gs) as a hepatoprotective agent against ethanol(Et oH)-induced toxicity in rats. METHoDS: Male Wistar rats weighing 200-230 g were subjected to a 70% partial hepatectomy(PH); they were then divided into three groups(groups 1-3). During the experiment, animals in group 1 drank only water. The other two groups(2-3) drank an aqueous solution of Et oH(40%, v/v). Additionally, rats in group 3 received a Gs extract daily at a dose of 300 mg/kg body weight intragastically. Subsequently, to identify markers of liver damage in serum, alanine aminotransferase, aspartate aminotransferase, albumin and bilirubin were measured by colorimetric methods. Glucose, triglyceride and cholesterol concentrations were also determined. In addition, oxidative damage was estimated by measuring lipid peroxidation [using thiobarbituric-acid reactive substances(TBARS)] in both plasma and the liver and by measuring the total concentration of antioxidants in serum and the total antioxidant capacity in the liver. In addition, a liver mass gain assessment, total DNA analysis and a morpho-histological analysis of the liver from animals in all three groups were performed and compared. Finally, the number of deaths observed in the three groups was ***: Administration of the Geranium shiedeanum extract significantly reduced the unfavorable effect of ethanol on liver regeneration(restitution liver mass: PHEt oH group 60.68% vs PH-Gs-Et oH group 69.22%). This finding was congruent with the reduced levels of hepatic enzymes and the sustained or increased levels of albumin and decreased bilirubin in serum. The extract also modified the metabolic processes that regulate glucose and lipid levels, as observed from the serum measurements. Lower antioxidant levels and the liver damage induced by Et oH administration appeared to be mitigated by the extract, as observed from the TBARs(PH-Et oH group 200.14 mmol/mg vs PH-Gs-Et oH group 5

关键词： Geranium schiedeanum Liver regeneration Ethanol Free radicals Nuclear factor erythroid-2-relatedfactor 2