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Neural Regeneration Research 2024年第3期19卷 469-470页

作者： Ephraim f.Trakhtenberg Department of Neuroscience University of Connecticut School of MedicineFarmingtonCTUSA

Studies from nearly 3 decades ago suggested that,in the central nervous system(CNS),myelination of axons by oligodendrocytes not only helps improve axonal conductivity but also stabilizes circuitry(Colello and Schwab,1994).Over the years,myelin sheaths produced by oligodendrocytes have been found to contain multiple molecules that are inhibitory to axonal growth(e.g.,MAG,NogoA,OMgp,Semaphorins)(Yiu and He,2006;Silver et al.,2014).After white matter injury in the adult CNS,myelin debris from damaged axons and dead oligodendrocytes accumulates in the forming glial scar and exposes these myelin-associated axon growth-inhibitory molecules to the injured axonal stumps,thereby contributing to the inhibition of axonal *** development,CNS axons reach their postsynaptic targets and stop growing before oligodendrocytes appear and myelinate them(foran and Peterson,1992;Dangata et al.,1996).Therefore,myelin-associated axon growth-inhibitory molecules interacting with already grown axons during myelination were thought to block axons from promiscuous sprouting and miswiring,thereby stabilizing neural circuitry in the CNS(Colello and Schwab,1994).

关键词： thereby white injury

An unexpected cellular fountain of youth:platelets provide factors rejuvenating brain functions

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Signal Transduction and Targeted Therapy 2024年第1期9卷 16-18页

作者： Harald f.langer Department of Cardiology AngiologyHaemostaseology and Medical Intensive CareUniversity Medical Centre MannheimMedical Faculty MannheimHeidelberg UniversityMannheimGermany German Centre for Cardiovascular Research(DZHK) Partner Site Heidelberg/MannheimMannheimGermany European Center for Angioscience Medical Faculty MannheimHeidelberg UniversityMannheimGermany Cardiovascular systems biology Medical Clinic IUniversity Heart Center LübeckLübeckGermany

In a recent manuscript published in Nature,Schroer et *** that platelets and in particular platelet derived Pf-4(CXCl4)are a novel factor,which can rejuvenate the mammalian neuronal system.1 These findings have the potential to trigger an entire new field of research opening new platelet-derived candidate effector molecules for supporting regeneration.

关键词： supporting platelets finding

氮碳包封fe_(3)C纳米颗粒作为高效富氧还原电催化剂

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Science China Materials 2024年第3期67卷 762-770页

作者：汪翠萍李智雷杰李松 Stijn f.l.Mertens 胡劲松 School of Chemical Engineering Anhui Province Key Laboratory of Specialty PolymersAnhui University of Science and TechnologyHuainan 232001China Department of Chemistry Energy Lancaster and Materials Science LancasterLancaster UniversityLancaster LA14YBUnited Kingdom Institute of Energy Hefei Comprehensive National Science CenterHefei 230031China

高活性MOf基催化剂的设计和合成为促进动力学不利的氧还原反应(ORR)过程开辟了新的途径.本研究通过在ZIf-8前驱体表面涂覆二茂铁甲酸,然后进行两步炭化工艺,设计和制备了一种具有新型结构的高效电催化剂,以提高ORR性能.两步炭化过程对... 详细信息

高活性MOf基催化剂的设计和合成为促进动力学不利的氧还原反应(ORR)过程开辟了新的途径.本研究通过在ZIf-8前驱体表面涂覆二茂铁甲酸,然后进行两步炭化工艺,设计和制备了一种具有新型结构的高效电催化剂,以提高ORR性能.两步炭化过程对于将热解fe_(3)C纳米颗粒封装到碳纳米管(CNTs)中以及将fe单原子隔离到N掺杂碳(NC)基体上至关重要.此外,fe元素的相对含量对优化催化剂的ORR性能至关重要.所制得fe_(3)C@CNTs/NC-M催化剂结构先进,在碱性溶液中表现出良好的长期稳定性和电催化ORR性能,其半波电位和极限电流分别达到0.941 V和6.31 mA cm^(-2).此外,该电催化剂在甲醇溶液中具有较强的耐受性和良好的稳定性.fe_(3)C@CNTs/NC-M锌空气电池(ZAB)具有1.525 V的开路电位,420 mA cm^(-2)时的峰值功率密度为348 mW cm^(-2),10 mA cm^(-2)时的最大容量为843 mA h g_(Zn)^(-1).因此,这种合成策略为构建具有有效和稳定的ORR性能的MOf基电催化材料提供了一条有效途径.

关键词： metal-organic frameworks carbon nanotubes N-doped carbon matrix oxygen reduction reaction Zn-air battery

The viscous strip approach to simplify the calculation of the surface acoustic wave generated streaming

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 711-724页

作者： f.JAZINI DORCHEH M.GHASSEMI fuel Cells and Nano Systems(fCNS)laboratory Department of Mechanical EngineeringK.N.Toosi University of TechnologyTehran 19697Iran

In recent decades,the importance of surface acoustic waves,as a biocompatible tool to integrate with microfluidics,has been proven in various medical and biological *** numerical modeling of acoustic streaming caused by surface acoustic waves in microchannels requires the effect of viscosity to be considered in the equations which complicates the *** this paper,it is shown that the major contribution of viscosity and the horizontal component of actuation is concentrated in a narrow region alongside the actuation *** the inviscid equations are considerably easier to solve,a division into the viscous and inviscid domains would alleviate the computational load *** particles'traces calculated by this approximation are excellently alongside their counterparts from the completely viscous *** is also shown that the optimum thickness for the viscous strip is about 9-fold the acoustic boundary layer thickness for various flow patterns and amplitudes of actuation.

关键词： surface acoustic wave microfluidics numerical simulation particle tracing acoustic streaming

Graphene-calcium carbonate coating to improve the degradation resistance and mechanical integrity of a biodegradable implant

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Journal of Magnesium and Alloys 2024年第1期12卷 394-404页

作者： lokesh Choudhary Parama Chakraborty Banerjee R.K.Singh Raman Derrek E.lobo Christopher D.Easton Mainak Majumder frank Witte Jörg f.löffler Department of Mechanical and Aerospace Engineering Monash UniversityClayton CampusMelbourneVIC 3800Australia Department of Chemical and Biological Engineering Monash UniversityClayton CampusMelbourneVIC 3800Australia Nanoscale Science and Engineering laboratory(NSEl) Bldg 37Monash UniversityClayton CampusMelbourneVIC 3800Australia CSIRO Materials Science and Engineering Bayview AvenueClaytonVIC 3168Australia Julius Wolff Institute and Berlin Brandenburg Center for Regenerative Therapies Charité–Universitätsmedizin BerlinAugustenburger Platz 113353 BerlinGermany laboratory of Metal Physics and Technology Department of MaterialsETH Zurich8093 ZurichSwitzerland

Biodegradable implants are critical for regenerative orthopaedic procedures,but they may suffer from too fast corrosion in human-body *** necessitates the synthesis of a suitable coating that may improve the corrosion resistance of these implants without compromising their mechanical *** this study,an AZ91 magnesium alloy,as a representative for a biodegradable Mg implant material,was modified with a thin reduced graphene oxide(RGO)-calcium carbonate(CaCO_(3))composite *** analytical and in-vitro electrochemical characterization reveals that this coating significantly improves the corrosion resistance and mechanical integrity,and thus has the potential to greatly extend the related application field.

关键词： Graphene coating Biodegradable implant Hydroxyapatite Corrosion Magnesium alloy

Stubborn Hypoxia in Neonates with D-Transposition of the Great Arteries after Arterial Switch Operation: Central Sleep Apnea as the Cause and Potential Indicator of Brain Immaturity

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Congenital Heart Disease 2024年第2期19卷 185-195页

作者： Camden l.Hebson Kyle Bliton Amr Y.Hammouda Kaitlyn Barr W.Hampton Gray Mohini Gunnett Waldemar f.Carlo Department of Pediatrics Division of Pediatric CardiologyUniversity of Alabama BirminghamBirmingham35233USA Department of Pediatrics Division of Pediatric PulmonologyUniversity of Alabama BirminghamBirmingham35233USA Department of Pediatrics University of Alabama BirminghamBirmingham35233USA Department of Surgery Division of Cardiothoracic SurgeryUniversity of Alabama BirminghamBirmingham35233USA

D-transposition of the great arteries(d-TGA)is surgically repaired with the arterial switch operation(ASO)with excellent results,however short and long-term morbidities still develop including neurocognitive *** significant central sleep apnea is uncommon in non-premature infants,but when present indicates immature autonomic control of respiration likely due to a neurologic *** report the unanticipatedfinding of central sleep apnea in four-term neonates with d-TGA after uncomplicated ASO,with the short-term complication of delayed hospital discharge and long-term concerns regarding this early marker of brain immaturity and its hindrance to normal *** this report,we will review each patient’s clinical course and then examine the literature on pediatric central sleep apnea,neurodevelopmental outcomes after ASO,and the important overlap of these entities in the care of patients going forward.

关键词： Transposition congenital heart disease sleep apnea polysomnography

Some facets of the Mg/Na_(3)VCr_(0.5)fe_(0.5)(PO_(4))_(3) battery

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Chinese Chemical letters 2024年第10期35卷 469-473页

作者： Gregorio f.Ortiz Xiamen Key laboratory of Optoelectronic Materials and Advanced Manufacturing Institute of Luminescent Materials and Information DisplaysCollege of Materials Science and EngineeringHuaqiao UniversityXiamen 361021China

Magnesium rechargeable batteries(MRBs)present opportunities for grid-scale energy storage applications as a complement to li-ion batteries(lIBS).The major challenges are the low reversible capacity,inferior cycling stability and unsatisfactory energy ***_(3)VCr_(0.5)fe_(0.5)(PO_(4))_(3) with a well-defined NASIONtype structure is used as cathode in Mg ***-electrons reaction(~116 m Ah/g),1.5 V average voltage and 65%of capacity retention over 100 cycles are *** is inserted by a biphasic reaction with the participation of V3+/V4+/V5+redox couples in the electrochemical reaction while the non-active redox couples such as Cr^(3+)/Cr^(4+)and fe2+/fe^(3+)served as stabilizer to buffer the volume variation.A thermal stability up to~412℃ is also ***,incorporating a mixture of three transition metal(V/Cr/fe)in this type of structures will broaden new perspectives for realizing high performance cathodes for MRBs.

关键词： Multi-electron reaction Mg batteries NASICON Na_(3)VCr_(0.5)fe_(0.5)(PO_(4))_(3) Ironand chromium doping

Antimicrobial,antibiofilm,angiogenesis,anti-inflammatory,and wound healing activities of zinc nanoparticles green synthesized using ferula macrecolea extract

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Asian Pacific Journal of Tropical Biomedicine 2024年第6期14卷 259-268页

作者： Sultan f.Alnomasy Department of Medical laboratories Sciences College of Applied Medical SciencesShaqra UniversityAl-Quwayiyah 19257Saudi Arabia

Objective:To assess the antimicrobial,antibiofilm,anti-inflammatory,angiogenic,and wound healing activities of zinc nanoparticles(ZNPs)green synthesized using ferula macrecolea ***:The green synthesis was conducted using the precipitation ***,the minimum inhibitory concentration(MIC),minimum bactericidal concentration(MBC),and minimum biofilm inhibition concentration 50%(MBIC50)of ZNPs against Staphylococcus aureus(***)and Pseudomonas aeruginosa(***)were *** effects of ZNPs on the gene expressions of Staphylococcus spp.[intracellular adhesion A(icaA)and D(icaD)]and ***(rhlI and rhlR)were investigated using quantitative real-time *** addition,the effects of ZNPs on wound healing,angiogenesis,and anti-inflammatory markers were ***:The green-synthesized ZNPs demonstrated significant antimicrobial efficacy against *** and *** biofilm formation in *** and *** was also inhibited by ZNPs with MBIC50 values of 3.30μg/ml and 2.08μg/ml,***,ZNPs downregulated the expression of biofilm-related genes icaA,icaD,rhlI,and rhlR in the tested *** also demonstrated promising in vitro wound healing effects by promoting fibroblast cell proliferation and wound closure in a dose-dependent manner.A significant increase in the expression of HlA-G5 and VEGf-A genes as well as a marked decrease in the expression of Nf-κB,Il-1β,and TNf-αgenes were observed in cells treated with ZNPs compared to the control group(Plusions:ZNPs display promising antibacterial effects against *** and *** and wound-healing effects by inhibiting biofilm formation,inducing angiogenesis,and reducing ***,further studies must be conducted to specify the accurate mechanisms of action and toxicity of ZNPs.

关键词： Wound healing Antibacterial Angiogenesis Nanomedicine ferula macrecolea Inflammation

fast efficient photon deceleration in plasmas by using two laser pulses at different frequencies

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Matter and Radiation at Extremes 2024年第3期9卷 11-18页

作者： Y.X.Wang X.l.Zhu S.M.Weng P.li X.f.li H.Ai H.R.Pan Z.M.Sheng Key laboratory for laser Plasmas(moe) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China Collaborative Innovation Center of Ifsa Shanghai Jiao Tong UniversityShanghai 200240China Research Center of laser fusion of China Academy of Engineering Physics MianyangSichuan 621900China State key laboratory of High field laser Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Tsung-dao lee Institute Shanghai Jiao Tong UniversityShanghai 200240China

The generation of ultrashort high-power light sources in the mid-infrared(mid-IR)to terahertz(THz)range is of interest for applications in a number of fields,from fundamental research to biology and *** conventional laser technology,photon deceleration in plasma wakes provides an alternative approach to the generation of ultrashort mid-IR or THz ***,we present a photon deceleration scheme for the efficient generation of ultrashort mid-IR or THz pulses by using an intense driver laser pulse with a relatively short wavelength and a signal laser pulse with a relatively long *** signal pulse trails the driver pulse with an appropriate time delay such that it sits at the front of the second wake bubble that is driven by the driver *** to its relatively long wavelength,the signal pulse will be subjected to a large gradient of the refractive index in the plasma wake ***,the photon deceleration in the plasma wake becomes faster and more efficient for signal pulses with longer *** greatly enhances the capacity and efficiency of photon deceleration in the generation of ultrashort high-power light sources in the long-wavelength IR and THz spectral ranges.

关键词： laser ultrashort photon

Attempts to restore loss of function in damaged ACD cells open the way to non-mutational oncogenesis

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Genes & Diseases 2024年第3期11卷 5-6页

作者： Vladimir f.Niculescu 86420 Diedorf Germany Kirschenweg

This correspondence to Gene&Diseases calls attention to the controversy between proponents of genetic modification in carcinogenesis and supporters of non-mutational *** from molecular cancer research and findings from evolutionary cancer cell biology support the latter claim and provide no rationale for the mutational origin of sporadic *** is more conceivable that the general susceptibility of asymmetric cell division(ACD)phenotypes to oxygen leads to irreparable DNA defects and dysregulated defective symmetric cell division(DscD)phenotypes.

关键词： rational latter finding