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Intervention at an early threshold for post-hemorrhagic ventricular dilatation in preterm infants: a systematic review and meta-analysis

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World Journal of Pediatrics 2024年第8期20卷 774-786页

作者： Patrick Blundell Lloyd Abood Mallinath Chakraborty Sujoy banerjee Regional Neonatal Intensive Care Unit University Hospital of WalesCardiffUK Neonatal Unit Singleton HospitalSwanseaSA28QAUK Centre for Medical Education School of MedicineCardiff UniversityCardiffUK

Background Very few adequately powered studies exploring early thresholds for intervention in the management of post-hemorrhagic ventricular dilatation(PHVD)in preterm infants have identified consistent neurodevelopmental advantages at 12–30 *** aimed to conduct a meta-analysis on the efficacy and safety of early versus conservative thresholds for intervention,primarily aimed at normalizing cerebrospinal fluid(CSF)pressure,in the management of PHVD in preterm *** Multiple databases were searched for eligible papers,and prospective randomized trials involving preterm infants were *** results are expressed as relative risks(RRs)with 95%confidence intervals(CIs).the main outcome was survival without moderate-to-severe neurodevelopmental impairment at 12–30 *** ten articles representing seven randomized trials comparing early versus conservative thresholds for interventions were *** trials(n=545 infants)reported no difference in the main outcome between early and conservative groups[RR 0.99(0.71,1.37)].Sensitivity analysis excluding data from a medication trial did not alter the main outcome[RR 1.15(0.95,1.39)].Infants in the early threshold group received significantly more interventions[RR 1.48(1.05,2.09)].Deaths before discharge/during the initial study period[RR 1.04(0.70,1.54)]or a composite of death or shunt insertion[RR 1.04(0.86,1.27)]were comparable between the two *** Early intervention for PHVD,before a clinical or ultrasound threshold is met,leads to additional clinical procedures but does not improve survival without moderate–severe neurodevelopmental impairment at 12–30 *** should be exercised in interpreting these results due to significant variation between the studies.

关键词： Hydrocephalus Intraventricular hemorrhage Lumbar puncture Mortality Neurodevelopment Preterm infants

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transverse momentum balance of dijets in Xe+Xe collisions at the LHC

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Nuclear Science and techniques 2024年第7期35卷 137-146页

作者： Yao Li Shu-Wan Shen sa Wang Ben-Wei Zhang key Laboratory of Quark&Lepton Physics(MOE)and Institute of Particle Physics Central China Normal UniversityWuhan430079China College of Science China Three Gorges UniversityYichang443002China Center for Astronomy and Space Sciences and Institute of Modern Physics China Three Gorges UniversityYichang443002China Guangdong-Hong kong Joint Laboratory of Quantum Matter Guangdong Provincial Key Laboratory of Nuclear ScienceSouthern Nuclear Science Computing CenterSouth China Normal UniversityGuangzhou510006China

We present a theoretical study of the medium modifications of the p_(t)balance (x_(J)) of dijets in Xe+Xe collisions at■.the initial production of dijets was carried out using the POWHEG+PYtHIA8 prescription,which matches the next-toleading-order (NLO) QCD matrix elements with the parton shower (PS) *** SHELL model described the in-medium evolution of nucleus–nucleus collisions using a transport *** theoretical results of the dijet xJin the Xe+Xe collisions exhibit more imbalanced distributions than those in the p+p collisions,consistent with recently reported AtLAS *** utilizing the Interleaved Flavor Neutralisation,an infrared-and-collinear-safe jet flavor algorithm,to identify the flavor of the reconstructed jets,we classify dijets processes into three categories:gluon–gluon (gg),quark–gluon (qg),and quark–quark (qq),and investigated the respective medium modification patterns and fraction changes of the gg,qg,and qq components of the dijet sample in Xe+Xe *** is shown that the increased fraction of qg component at a small x_(J)contributes to the imbalance of the dijet;in particular,the q_(1)g_(2)(quark-jet-leading) dijets experience more significant asymmetric energy loss than the g_(1)q_(2)(gluon-jet-leading) dijets traversing the *** comparing the■of inclusive,■ dijets in Xe+Xe collisions,we observe■.Moreover,ρ_(Xe),P_(b),the ratios of the nuclear modification factors of dijets in Xe+Xe to those in Pb+Pb,were calculated,which indicates that the yield suppression of dijets in Pb+Pb is more pronounced than that in Xe+Xe owing to the larger radius of the lead nucleus.

关键词： Heavy-ion collisions Quark-gluon plasma Jet quenching transverse momentum balance

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Role of renin-angiotensin system/angiotensin converting enzyme-2 mechanism and enhanced COVID-19 susceptibility in type 2 diabetes mellitus

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World Journal of Diabetes 2024年第4期15卷 606-622页

作者： Ashwin kumar Shukla komal Awasthi kauser Usman Monisha banerjee Molecular and Human Genetics Laboratory Department of ZoologyUniversity of LucknowLucknow 226007Uttar PradeshIndia Department of Medicine King Georges’Medical UniversityLucknow 226003Uttar PradeshIndia Institute of Advanced Molecular Genetics and Infectious Diseases(IAMGID)University of LucknowLucknow 226007Uttar PradeshIndia

Coronavirus disease 2019(COVID-19)is a disease that caused a global pandemic and is caused by infection of severe acute respiratory syndrome coronavirus 2 *** has affected over 768 million people worldwide,resulting in approx-imately 6900000 ***-risk groups,identified by the Centers for Disease Control and Prevention,include individuals with conditions like type 2 diabetes mellitus(t2DM),obesity,chronic lung disease,serious heart conditions,and chronic kidney *** indicates that those with t2DM face a hei-ghtened susceptibility to COVID-19 and increased mortality compared to non-diabetic *** the renin-angiotensin system(RAS),a vital regulator of blood pressure and pulmonary stability,reveals the significance of the angiotensin-converting enzyme(ACE)and ACE2 *** converts angiotensin-I to the vasoconstrictor angiotensin-II,while ACE2 counters this by converting angiotensin-II to angiotensin 1-7,a *** ACE2 exp-ression,common in diabetes,intensifies RAS activity,contributing to conditions like inflammation and *** ACE inhibitors and angiotensin receptor blockers can be therapeutically beneficial by increasing ACE2 levels,concerns arise regarding the potential elevation of ACE2 receptors on cell membranes,potentially facilitating COVID-19 *** review explored the role of the RAS/ACE2 mechanism in amplifying severe acute respiratory syndrome cor-onavirus 2 infection and associated complications in *** treatment strategies,including recombinant human ACE2 therapy,broad-spectrum antiviral drugs,and epigenetic signature detection,are discussed as promising avenues in the battle against this pandemic.

关键词： Angiotensin-converting enzyme 2 Angiotensin-converting enzyme inhibitors Angiotensin-II receptor blockers Complex diseases COVID-19 type 2 diabetes

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Intrusion Detection System Using Classification Algorithms with Feature Selection Mechanism over Real-time Data traffic

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China Communications 2024年第9期21卷 292-320页

作者： Gulab sah Sweety Singh Subhasish banerjee Computer Science and Engineering National Institute of Technology Arunachal PradeshIndia

the key objective of intrusion detection systems(IDS)is to protect the particular host or network by investigating and predicting the network traffic as an attack or *** IDS uses many methods of machine learning(ML)to learn from pastexperience attack *** based and identify the new *** though these methods are effective,but they have to suffer from large computational costs due to considering all the traffic features,***,emerging technologies like the Internet of things(Io t),big data,*** getting advanced day by day;as a result,network traffics are also increasing ***,the issue of computational cost needs to be addressed ***,in this research,firstly,the ML methods have been used with the feature selection technique(FSt)to reduce the number of features by picking out only the important ones from NSL-kDD,CICIDS2017,and CIC-DDo S2019datasets later that helped to build IDSs with lower cost but with the higher performance which would be appropriate for vast scale *** experimental result demonstrated that the proposed model *** tree(Dt)with Recursive feature elimination(RFE)performs better than other classifiers with RFE in terms of accuracy,specificity,precision,sensitivity,F1-score,and G-means on the investigated datasets.

关键词： CICIDS2017 dataset classifiers IDS ML NSL kDD dataset RFE

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Data-driven analysis of chemicals,proteins and pathways associated with peanut allergy:from molecular networking to biological interpretation

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Food Science and Human Wellness 2024年第3期13卷 1322-1335页

作者： Emmanuel kemmler Julian Braun Florent Fauchère sabine Dölle-Bierke kirsten Beyer Robert Preissner Margitta Worm Priyanka banerjee Institute for Physiology Charité-University Medicine BerlinBerlin 10115Germany Member of the kFO339 FOOD@Berlin 10115Germany Si-M/“Der Simulierte Mensch”a science framework of technische Universität Berlin and Charité-Universitätsmedizin Berlin Berlin 10115Germany Charité-Universitätsmedizin Berlin corporate member of Freie Universität BerlinHumboldt-Universität zu Berlinand Berlin Institute of HealthBerlin 10115Germany Division of Allergy and Immunology Department of DermatologyVenerology and AllergyCharité-Universitätsmedizin Berlincorporate member of Freie Universität Berlin and Humboldt-Universität zu BerlinBerlin 10115Germany Pediatrics Campus VirchowCharité-University Medicine BerlinBerlin 10115Germany

Peanut allergy is majorly related to severe food induced allergic *** food including cow's milk,hen's eggs,soy,wheat,peanuts,tree nuts(walnuts,hazelnuts,almonds,cashews,pecans and pistachios),fish and shellfish are responsible for more than 90%of food ***,we provide promising insights using a large-scale data-driven analysis,comparing the mechanistic feature and biological relevance of different ingredients presents in peanuts,tree nuts(walnuts,almonds,cashews,pecans and pistachios)and ***,we have analysed the chemical compositions of peanuts in different processed form raw,boiled and *** the data-driven approach we are able to generate new hypotheses to explain why nuclear receptors like the peroxisome proliferator-activated receptors(PPARs)and its isoform and their interaction with dietary lipids may have significant effect on allergic *** results obtained from this study will direct future experimeantal and clinical studies to understand the role of dietary lipids and PPARisoforms to exert pro-inflammatory or anti-inflammatory functions on cells of the innate immunity and influence antigen presentation to the cells of the adaptive immunity.

关键词： Allergy informatics knowledge-graph Data analysis Food allergy Peroxisome proliferator-activated receptors Fatty acids

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Evaluating new biomarkers for diabetic nephropathy:Role ofα2-macroglobulin,podocalyxin,α-L-fucosidase,retinol-binding protein-4,and cystatin C

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World Journal of Diabetes 2024年第6期15卷 1212-1225页

作者： Jing-Jing Li Ru-La sa Yu Zhang Zhao-Li Yan Department of Infectious Diseases Inner Mongolia Medical UniversityHohhot First HospitalHohhot 010000Inner Mongolia Autonomous RegionChina Department of Endocrinology The Affiliated Hospital of Inner Mongolia Medical UniversityHohhot 010000Inner Mongolia Autonomous RegionChina Department of Dermatology Inner Mongolia Autonomous Region People’s HospitalHohhot 010000Inner Mongolia Autonomous RegionChina

BACkGROUND the intricate relationship between type 2 diabetes mellitus(t2DM)and diabetic nephropathy(DN)presents a challenge in understanding the significance of various biomarkers in *** to elucidate the roles and diagnostic values ofα2-macroglobulin(α2-MG),podocalyxin(PCX),α-L-fucosidase(AFU),retinol-binding protein-4(RBP-4),and cystatin C(CysC)in *** From December 2018 to December 2020,203 t2DM patients were enrolled in the *** these,115 were diagnosed with DN(115 patients),while the remaining 88 patients were classified as *** urinary levels ofα2-MG,PCX,and AFU and the serum concentrations RBP-4 and CysC were measured in conjunction with other relevant clinical indicators to evaluate their potential correlations and diagnostic *** After adjustments for age and gender,significant positive correlations were observed between the biomarkers CysC,RBP-4,α2-MG/urinary creatinine(UCr),PCX/UCr,and AFU/UCr,and clinical indicators such as urinary albumin-to-creatinine ratio(UACR),serum creatinine,urea,24-h total urine protein,and neutrophil-to-lymphocyte ratio(NLR).Conversely,these biomarkers exhibited negative correlations with the estimated glomerular filtration rate(Pting characteristic(ROC)curve analysis further demonstrated the diagnostic performance of these biomarkers,with UACR showcasing the highest area under the ROC curve(AUC^(ROC))at *** this study underscores the diagnostic significance ofα2-MG,PCX,and AFU in the development of *** biomarkers RBP-4,CysC,PCX,AFU,andα2-MG provide promising diagnostic insights,while UACR is the most potent diagnostic biomarker in assessing DN.

关键词： α2-macroglobulin Podocalysin α-L-fucosidase Retinol binding protein-4 Cystatin C Diabetic nephropathy

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Superior Latent Heat Eutectic salt Na_(2)CO_(3)-Li_(2)CO_(3)-LiF for thermal Energy Storage:Preparation and Performance Investigation

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Journal of thermal Science 2024年第2期33卷 501-508页

作者： LI Weiwei MIAO Qi ZHANG Yelong DING Hongliang YANG sa LAI Yuan FENG Daili DING Yulong JIN Yi tAN Linghua School of Chemistry and Chemical Engineering Nanjing University of Science&TechnologyNanjing210094China National Special Superfine Powder Engineering Research Center Nanjing University of Science and TechnologyNanjing210094China Nanjing Jinhe Energy Material Co. LtdNanjing210047China School of Chemical Engineering University of BirminghamBirminghamB152TTUK School of Energy&Environmental Engineering University of Science and Technology BeijingBeijing100083China

In this paper,a novel ternary eutectic salt Na_(2)CO_(3)-Li_(2)CO_(3)-LiF was designed and investigated for concentrated solar power(CSP).the Factsage software was used to predict the composition and eutectic point of Na_(2)CO_(3)-Li_(2)CO_(3)-*** microstructure,thermophysical properties,and thermal stability of eutectic salts were experimentally measured using various analytical *** a mass ratio of 57%:32%:11%,the eutectic salt exhibited excellent thermal storage properties with a fusion enthalpy of 413 J/g and a melting point of 426.8℃.the excellent thermal stability of the eutectic salt was reflected by a weight loss of only 0.8% at 600℃.

关键词： phase change materials ternary eutectic salt latent heat thermal stability

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钒技术在难减排行业和能源转型中的作用评估

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钢铁钒钛 2024年第4期45卷 84-94页

作者： David Asantos Manish kDixit Pranav Pradeep kumar sarbajit banerjee 德克萨斯农工大学化学系德克萨斯农工大学材料科学和工程系德克萨斯农工大学建筑科学系德克萨斯农工大学土木与环境工程学院

重工业的减碳和可再生能源技术的出现皆与获得矿物资源有着密不可分的联系。因此，迫切需要对关键元素在减少温室气体排放方面的作用进行基准评估。考察了钒作为微合金元素在建筑碳减排以及作为电网储能用液流电池的主要成分在能源转型... 详细信息

重工业的减碳和可再生能源技术的出现皆与获得矿物资源有着密不可分的联系。因此，迫切需要对关键元素在减少温室气体排放方面的作用进行基准评估。考察了钒作为微合金元素在建筑碳减排以及作为电网储能用液流电池的主要成分在能源转型中的作用。研究结果表明，钒可使每年减少总计1.85亿t碳排放。其中，中国和欧盟的减排幅度分别为各自排放量的1.15%和0.18%。研究结果强调了关键金属在发展低碳基础设施中的作用，同时指出了进行全面评估并施加政策干预减轻供应链风险的必要性。

关键词：钒微合金化液流电池碳减排

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Comparative impact behaviours of ultra high performance concrete columns reinforced with polypropylene vs steel fibres

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Defence technology（防务技术） 2024年第10期40卷 138-153页

作者： thong M.Pham Harrison Hyde Maw k.kaung Yan Zhuge Duong t.tran Des Vlietstra tung M.tran Unisa STEMUniversity of South AustraliaMawson LakesSA 5095Australia BG&E Pty Ltd Wellington StreetPerthWA6000Australia Austral Construction Pty Ltd St Georges TerracePerthWA6000Australia Centre for Infrastructural Monitoring and Protection(CIMP) Curtin UniversityKent StBentleyWA 6102Australia Barchip Australia Pty Ltd U 26 Qualtroughq StreetWoolloongabbaQueensland4102Australia Sustainable Developments in Civil Engineering Research Group Faculty of Civil EngineeringTon Duc Thang UniversityHo Chi Minh City72915Viet Nam

Polypropylene(PP)fibres have primarily used to control shrinkage cracks or mitigate explosive spalling in concrete structures exposed to fire or subjected to impact/blast loads,with limited investigations on capacity *** study unveils the possibility of using PP micro-fibres to improve the impact behaviour of fibre-reinforced ultra-high-performance concrete(FRUHPC)*** show that the addition of fibres significantly improves the impact behaviour of FRUHPC columns by shifting the failure mechanism from brittle shear to favourable flexural *** addition of steel or PP fibres affected the impact responses *** fibres considerably increased the peak impact force(up to 18%)while PP micro-fibres slightly increased the peak(3%-4%).FRUHPC significantly reduced the maximum midheight displacement by up to 30%(under 20impact)and substantially improved the displacement recovery by up to 100%(under 20impact).FRUHPC with steel fibres significantly improved the energy absorption while those with PP micro-fibres reduced the energy absorption,which is different from the effect of PP-macro fibre reported in the *** optimal fibre content for micro-PP fibres is 1%due to its minimal fibre usage and low peak and residual *** study highlights the potential of FRUHPC as a promising material for impact-resistant structures by creating a more favourable flexural failure mechanism,enhancing ductility and toughness under impact loading,and advancing the understanding of the role of fibres in structural performance.

关键词： Ultra high-performance concrete Steel fibre Polypropylene micro-fibre Fibre volume fraction Impact loading Pendulum tests Columns

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Jet modification in absence of QGP-medium:the role of multiparton interactions and color reconnection

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Chinese Physics C 2024年第1期48卷 50-60页

作者： Prottoy Das Abhi Modak Debjani banerjee Rathijit Biswas Supriya Das sanjay kGhosh Sibaji Raha Sidharth kumar Prasad Department of Physics Bose InstituteKolkata 700091India Quark Matter Research Center Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China

Recent studies on high-multiplicity events in small collision systems(proton-proton and proton-lead)have drawn considerable research interest toward the possibility of the formation of partonic medium in such *** of the important consequences of the formation of dense partonic medium is the quenching of high-momentum final-state particles,resulting in several experimental observations such as suppression in nuclear modification factor RAA,modification of jet shape observableρ(r)and jet fragmentation(z^(ch))distributions,*** this work,we studyρ(r)and z^(ch)for inclusive charged-particle jets in proton-proton(pp)collisions at√s=13 teV using the PYtHIA 8 Monash 2013 Monte Carlo *** show that the color reconnection(CR)and multiparton interaction(MPI)mechanisms in PYtHIA 8 can lead to an increased rate of jet *** also find that the mechanisms of MPI and CR and change in the gluonic contribution in high-multiplicity events result in significant modification ofρ(r)and z^(ch)compared to those in minimum bias events for 10t,jet)^(ch)tice a direct connection ofand gluonic contribution with the amount of modification inρ(r):the larger the number of MPIs and/or gluonic contribution,the larger the amount of modification ofρ(r).

关键词： jet modification PYtHIA multiparton interaction color reconnection gluonic contribution high-multiplicity

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