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Chinese Medical Sciences Journal 2007年第4期22卷 238-242页

作者： sa-ying li min chen rui wang cheng zhou Department of Radiology Beijing Hospital Ministry of Health Beijing 100730

Objective To quantitatively evaluate the metabolic changes of benign prostatic hyperplasia(BPH) and prostate cancer in the transitional zone using magnetic resonance spectroscopic imaging(MRSI),and to analyze the characteristics and differences of the spectra in this zonal *** Eighteen patients with prostate cancer in the transitional zone underwent magnetic resonance imaging(MRI)/MRSI ***(Choline+Creatine)/Citrate(CC/Ci) ratio and the Choline/Creatine(Cho/Cr) ratio were evaluated in each voxel with cancer or BPH confirmed by pathological *** analysis was used to determine the power of the two ratios in differentiation between cancer and *** The CC/Ci ratio and Cho/Cr ratio for cancer voxels were significantly higher than those in the voxels with BPH in the transitional zone(CC/Ci:2.36±1.31 vs.0.85±0.29,Pminant function with the CC/Ci ratio and the Cho/Cr ratio,the specificity,sensitivity,and accuracy were 98.6%,85.7%,92.9% respectively for the differentiation between cancer and *** The prostate cancer is characterized by higher CC/Ci ratio and Cho/Cr ratio compared to BPH in the transitional *** CC/Ci ratio and Cho/Cr ratio have high specificity,sensitivity,and accuracy in their discriminative power between cancer and BPH in this zonal area.

关键词： prostate cancer benign prostatic hyperplasia transitional zone magnetic resonance spectroscopic imaging

DIAGNOSTIC VALUE OF INTERICTAL DIFFUSION-WEIGHTED IMAGING IN EVALUATION OF INTRACTABLE TEMPORAL LOBE EPILEPSY

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Chinese Medical Sciences Journal 2008年第2期23卷 68-72页

作者： rui wang sa-ying li min chen cheng zhou Department of Radiology Beijing Hospital Beijing 100730

Objective To explore the ability of interictal diffusion-weighted imaging(DWI)to localize the temporal lobe of seizure origin and to predict postoperative seizure control in patients with temporal lobe epilepsy(TLE).Methods Twenty-seven patients with intractable TLE considered for surgery and 19 healthy volunteers were studied with conventional magnetic resonance imaging(MRI)and *** diffusion coefficients(ADCs)of bilateral hippocampi in both TLE patients and control subjects were *** to either temporal lobe with hippocampal ADC was based on the threshold values derived from ±1SD of right/left ratios in normal *** the postoperative pathology was *** Hippocampal ADCs were higher on the side of surgery compared with those on the contralateral side as well as the ipsilateral side in control subjects [resected side(109.8±7.3)×10-5 cm2/s,contralateral side(91.7±4.7)×10-5 cm2/s,control subjects(81.6±5.2)×10-5 cm2/s,all Plized to the operated temporal lobe in 21 of 27(77.8%)and in 18 of 27(66.7%)*** to the surgical side was not associated with postoperative seizure control with right/left hippocampal ADC ratio(P>0.05).Conclusions Conventional MRI is a sensitive method to detect hippocampal *** of the right/left hippocampal ADC ratio for lateralizing to the side of surgery is very high,but it isn't a better predictor of surgical outcome.

关键词： magnetic resonance imaging temporal lobe epilepsy epilepsy surgery

Advances in the role of natural products in human gene expression

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Chinese Journal of Natural Medicines 2022年第1期20卷 1-8页

作者： chen Gang zhou Di wang cheng-min li Ning School of Traditional Chinese Materia Medica Shenyang Pharmaceutical UniversityShenyang 110016China State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China

Natural products(NPs),especially those from traditional herbal medicines,can evidently modulate human gene expression at multiple levels,leading to a wide diversity of *** numerous bio-functions of NPs for human body have been found,there is little understanding about how NPs achieve it,as less attention was drawn to the definite mechnism by which NPs regulate gene ***,based on the rapidly advancing knowledge of mechanisms for gene regulation in recent years,newly-understood mechanisms,such as post-transcriptional regulation,are found to be involved in NP-elicited bio-effects,providing a new perspective on understanding the role of NPs in gene ***,in the current review,we summarize the function of NPs in gene expression from the perspectives of transcriptional,post-transcriptional,and post-translational regulation,which will reinforce the understanding of NP-induced effects in gene expression and facilitate the exploration of more NPs with potential therapeutic effects.

关键词： Natural products Gene expression Non-coding RNAs Post-transcriptional regulation

Enhanced rate capability and cycle stability of Ti2C MXene for sodium storage through an aniline molecules welding strategy

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Tungsten 2025年第1期 161-171页

作者： Hao chen Ya-Qin wang Dong-Ting Zhang Bei Zhao min-Peng li chen-Yang li Tian-Peng Xu Mao-cheng liu State Key Laboratory of Advanced Processing and Recycling of Non-Ferrous Metals Lanzhou University of Technology School of Materials Science and Engineering Lanzhou University of Technology School of Computer and Communication Technology Lanzhou University of Technology

MXenes obtained significant attention in the field of energy storage devices due to their characteristic layered structure,modifiable surface functional groups,large electrochemically active surface,and regulable interlayer ***,the self-restacking and sluggish ions diffusion kinetics performance of MXenes during the alkali metal ions insertion/extraction process severely impedes their cycle stability and rate *** paper proposes an aniline molecule welding strategy for welding p-phenylenediamine（PPDA） into the interlayers of Ti2C through a dehydration condensation *** welded PPDA molecules can contribute pillar effect to the layered structure of *** pillar effect effectively maintains the structural stability during the sodium ions insertion/extraction process and effectively expands the interlayer spacing of Ti2C from 1.16 to 1.38 nm,thereby enhancing ions diffusion kinetics performance and improving the long-term cycle *** Ti2C-PPDA demonstrates outstanding Na+storage capability,exhibiting a specific capacity of 100.2 mAh·g-1at a current density of 0.1 A·g-1over 960 cycles and delivering a remarkable rate capability 81.2 mAh·g-1at a current density of 5 A·*** study demonstrates that expanding interlayer spacing is a promising strategy to enhance the Na+storage capacity and improve long-term cycling stability,which provides significant guidance for the design of two-dimensional Na+storage materials with high-rate capability and cycle stability.

关键词：

ligand Steric Effects on Naphthyl-α-diimine Nickel Catalyzed α-Olefin Polymerization

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Chinese Journal of Polymer Science 2018年第2期36卷 157-162页

作者： Fu-zhou wang Su-Su Tian rui-Ping li Wei-min li Chang-Le chen Advanced Catalysis and Green Manufacturing Collaborative Innovation Center School of Pertrochemical Engineering Changzhou University Chinese Academy of Sciences Key Laboratory of Soft Matter Chemistry Department of Polymer Science and Engineering University of Science and Technology of China

Naphthyl-α-diimine nickel complexes with systematically varied ligand sterics, activated by modified methylaluminoxane（MMAO）, were tested in the polymerization of higher α-olefin（1-hexene, 1-decene and 1-hexadecene） under suitable conditions. The polymerization results indicated the possibility of precise microstructure control, depending on catalyst structure, polymerization temperature, monomer concentration and types of monomers, which in turn strongly affects the resultant polymer properties. Naphthyl-α-diimine nickel complex bearing chiral bulky sec-phenethyl groups in the o-naphthyl position showed good catalytic activity, and resulted in branched polymers（42-88/1000 C） with high molecular weights（Mn：（4.3-15.2） × 10^4 g·mol^-1） and narrow molecular weight distribution（Mw/Mn = 1.13-1.29, RT）, which suggested a living polymerization. The increasing steric hindrance of catalyst leads to enhance insertion for 2,1-insertion of α-olefin and the chain-walking reaction.

关键词： Naphthyl-α-diimine nickel complex Chain-walking polymerization Higher α-olefin Steric effect

DIFFERENTIATION BETWEEN MAliGNANT AND BENIGN OVARIAN TUMORS BY MAGNETIC RESONANCE IMAGING

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Chinese Medical Sciences Journal 2006年第4期21卷 270-275页

作者： min chen Wen-chao wang cheng zhou Ni-na zhou Kui Cai Zheng-han Yang Wei-feng Zhao sa-ying li Guo-zhen li Department of Radiology Beijing Hospital Beijing 100730

Objective To determine the magnetic resonance （MR） imaging findings of an ovarian mass which are most predictive of malignancy and assess the value of intravenous gadolinium administration in the characterization of an ovarian mass. Methods Totally 74 consecutive patients with a clinically or sonographicaUy indeterminate adnexal mass underwent MR imaging, of whom 59 had subsequent surgical resection of 70 adnexal masses. These 59 patients formed the study population. MR imaging studies were prospectively and independently reviewed by a senior and a junior radiologist. The senior radiologist also reevaluated the studies in a blind fashion after a minimum 6 months interval. The sensitivity, specificity, positive predictive value, and negative predictive value of contrast-enhanced and unenhanced MR im- aging were evaluated Results The most predictive MR imaging findings for malignancy were presence of vegetations in a cystic lesinn and presence of necrosis in a solid lesion. The odds ratio was even higher when the ancillary finding of peritoneal metastasis or ascites was present. Contrast media contributed significantly to lesinn characterization. Total 70 ovarian masses were detected by contrast-enhanced MR imaging including 37 malignant ovarian masses and 33 benign ovarian masses with 87% （61/70）accuracy, 86% （32/37）sensitivity, 88% （29/33）specificity, 89% （32/36）positive predictive value, and 85% （29/34） negative predictive value, whereas 70 ovarian masses were detected by unenhanced MR imaging with 74% （52/70） accuracy, 73 % （27/37） sensitivity, 76 % （ 25/33 ） specificity, 77% （27/35） positive predictive value, and 71% （ 25/35 ） negative predictive value. There were significant differences in accuracy （ P 〈 0. 01 ）, sensitivity （ P 〈0. 01 ）, specificity （ P 〈0. 01 ） between contrast-enhanced and unenhanced MR imaging. Conclusion Contrast-enhanced MR imaging is highly accurate in detection and characterization of complex adnexal masses.

关键词： ovarian tumor malignancy magnetic resonance imaging

Chemical characteristics of fine particles and their impact on visibility impairment in Shanghai based on a 1-year period observation

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Journal of Environmental Sciences 2016年第10期28卷 151-160页

作者： min zhou liping Qiao Shuhui Zhu li li Shengrong Lou Hongli wang Qian wang Shikang Tao cheng Huang Changhong chen State Environmental Protection Key Laboratory of the Cause and Prevention of Urban Air Pollution Complex Shanghai 200233 China Shanghai Academy of Environmental Sciences. Shanghai 200233 China

In this work, a one-year observation focusing on high time resolution characteristics of components in fine particles was conducted at an urban site in Shanghai. Contributions of different components on visibility impairment were also studied. Our research indicates that the major components of PM2.5 in Shanghai are water-soluble inorganic ions and carbonaceous aerosol, accounting for about 60% and 30% respectively. Higher concentrations of sulfate （SO42-） and organic carbon （OC） in PM2.s occurred in fall and summer, while higher concentrations of nitrate （NO3-） were observed in winter and spring. The mass concentrations of Cl- and K＋ were higher in winter. Moreover, NO3- increased significantly during PM2.s pollution episodes. The high values observed for the sulfate oxidizing rate （SOR）, nitrate oxidizing rate （NOR） and secondary organic carbon （SOC） in OC indicate that photochemical reactions were quite active in Shanghai. The IMPROVE （Interagency Monitoring of Protected Visual Environments） formula was used in this study to investigate the contributions of individual PM2.5 chemical components to the light extinction efficient in Shanghai. Both NH4NO3 and （NH4）aSO4 had close relationships with visibility impairment in Shanghai. Our results show that the reduction of anthropogenic SO2, NOx and NH3 would have a significant effect on the improvement of air qualitv and visibility in Shanghai.

关键词： PM2.5 Chemical compositionlight extinction efficientShanghai

Corrosion behavior of Ti60 alloy under continuous NaCl solution spraying at 600℃

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Journal of Materials Science & Technology 2022年第29期124卷 86-101页

作者： rui li li liu Yu Cui rui liu Lei Fan min Cao Zhongfen Yu Zhiyong chen Qingjiang wang Fuhui wang Shenyang National Laboratory for Materials Science Northeastern UniversityShenyang 110819China Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China State Key Laboratory for Performance and Structure safety of Petroleum Tubular Goods and Equipment Materials CNPC Tubular Goods Research InstituteXi’an 710077China China ENFI Engineering Corp ENFI R&D Institute.Beijing 100038China

The corrosion behavior of Ti60 alloy was investigated under continuous NaCl solution spraying at 600℃.Results indicate that the corrosion rate of the Ti60 alloy is lower than that obtained with the solid NaCl deposit film in HO+*** outer corrosion products are compact layers mainly containing NaTiOand nanocrystalline *** inner layer is mainly composed of TiO,Ti O and *** has a lamellar structure,and TiO has a strip-shaped structure.A mixed corrosion mechanism including classic oxidation and active oxidation occurred under NaCl solution spraying environment:the first stage was controlled by the classic oxidation mechanism with the promotion by the active oxidation following parabolic curves,and the second stage was controlled by the active oxidation mechanism following a linear rise in the mass gain *** mixed corrosion mechanism between classic oxidation and active oxidation produced a relatively dense Ti oxides scale,which decreased the corrosion rate.

关键词： Titanium alloy High temperature corrosion Continuous NaCl solution spraying

Recovery of iron from copper tailings via low-temperature direct reduction and magnetic separation: process optimization and mineralogical study

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International Journal of minerals,Metallurgy and Materials 2017年第9期24卷 974-982页

作者： rui-min Jiao Peng Xing cheng-yan wang Bao-zhong Ma Yong-Qiang chen School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

Currently, the majority of copper tailings are not effectively developed. Worldwide, large amounts of copper tailings generated from copper production are continuously dumped, posing a potential environmental threat. Herein, the recovery of iron from copper tailings via low-temperature direct reduction and magnetic separation was conducted; process optimization was carried out, and the corresponding mineralogy was investigated. The reduction time, reduction temperature, reducing agent (coal), calcium chloride additive, grinding time, and magnetic field intensity were examined for process optimization. mineralogical analyses of the sample, reduced pellets, and magnetic concentrate under various conditions were performed by X-ray diffraction, optical microscopy, and scanning electron microscopy-energy-dispersive X-ray spectrometry to elucidate the iron reduction and growth mechanisms. The results indicated that the optimum parameters of iron recovery include a reduction temperature of 1150A degrees C, a reduction time of 120 min, a coal dosage of 25%, a calcium chloride dosage of 2.5%, a magnetic field intensity of 100 mT, and a grinding time of 1 min. Under these conditions, the iron grade in the magnetic concentrate was greater than 90%, with an iron recovery ratio greater than 95%.

关键词： copper tailings iron direct reduction magnetic separation recovery process optimization

Gut-brain axis as a bridge in obesity and depression:Mechanistic exploration and therapeutic prospects

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World Journal of Psychiatry 2025年第1期15卷 12-20页

作者： rui-ying Fang Xiao-rui Pan Xin-Xing Zeng Zheng-Zheng li Bo-Fan chen Hai-min Zeng Jie Peng The Second Clinical Medical College The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina

A recent study by wang et al,published in the World Journal of Psychiatry,provided preventative and therapeutic strategies for the comorbidity of obesity and *** gut-brain axis,which acts as a two-way communication system between the gastrointestinal tract and the central nervous system,plays a pivotal role in the pathogenesis of these *** suggests that metabolic byproducts,such as short-chain fatty acids,lipopolysaccharide and bile acids,which are generated by the gut microbiota,along with neurotransmitters and inflammatory mediators within the gut-brain axis,modulate the host's metabolic processes,neuronal regulation,and immune responses through diverse *** interaction between obesity and depression via the gut-brain axis involves disruptions in the gut microbiota balance,inflammatory immune responses,and alterations in the neuroendocrine *** the gut-brain axis,for example,through a ketogenic diet,the use of probiotics,and the supplementation of antioxidants,offers new remedial approaches for obesity and *** research that explores the mechanisms of the gut-brain axis is needed to provide more evidence for clinical treatment.

关键词： Gut-brain axis Obesity Depression Gut microbiota Mechanism