检索结果-南通市图书馆

Mechanism of brittle-ductile transition of a glass-ceramic rigid substrate

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2011年第2期18卷 229-233页

作者： Yu-li sun Dun-wen Zuo Hong-yu Wang Yong-wei Zhu Jun li Jiangsu Key Laboratory of Precision and Micro-manufacturing Technology College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and Astronautics Nanjing 210016 China

The hardness, elastic modulus, and scratch resistance of a glass-ceramic rigid substrate were measured by nanoindentation and nanoscratch, and the fracture toughness was measured by indentation using a Vickers indenter. The results show that the hardness and elastic modulus at a peak indentation depth of 200 nm are 9.04 and 94.70 GPa, respectively. These values reflect the properties of the glass-ceramic rigid substrate. The fracture toughness value of the glass-ceramic rigid substrate is 2.63 MPa？m1/2. The material removal mechanisms are seen to be directly related to normal force on the tip. The critical load and scratch depth estimated from the scratch depth profile after scratching and the friction profile are 268.60 mN and 335.10 nm, respectively. If the load and scratch depth are under the critical values, the glass-ceramic rigid substrate will undergo plastic flow rather than fracture. The formula of critical depth of cut described by Bifnao et al. is modified based on the difference of critical scratch depth

关键词： brittle-ductile transition critical conditions glass ceramics nanoindentation nanoscratch

A Convenient Synthesis of Chrysin and Tectochrysin

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2001年第3期17卷 259-263页

作者： ZHU Jin-tao CHEN Ying-qi DAI li-yan sun li-wen YAO San-jing Zhejiang Engineering College Hangzhou 310033P.R.China Department of Chemical Engineering Zhejiang UniversityHangzhou 310013P.R.China

Chrysin(1) and tectochrysin(2) were respectively synthesized in four steps from 1,3,5-tribromobenzene in an overall yield of 46.8% and that of 37.0% with the key step being the Bu_4NBr catalyzed hydrolysis of 1-phenyl... 详细信息

关键词： Flavone Chrysin Tectochrysin Synthesis

Asymmetric Synthesis of (R)-and (S)-Moprolol

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2008年第6期24卷 747-751页

作者： WANG Zhao-yang WANG Yan sun li-wen ZHU Jin-tao Department of Chemistry Zhejiang Sci-Teeh University Hangzhou 310018 P. R. China Institute of Materia Mediea Zhejiang Aeademy of Medical Science Hangzhou 310013 P. R. China

A simple and effective procedure for the enantioselective synthesis of （R）- and （S）-moprolol was described. The key step was the asymmetric synthesis of enantiopure （R）- and （S）-guaifenesin, which were synthesized from enantioenriched （R）-3-chloro-l,2-propanediol and （S）-epichlorohydrin via kinetics of hydrolysis resolution of racemic epichlorohydrin by chiral Salen-Co^Ⅲ complex. The e.e. values of both the optical compounds were above 98%, and the chemical structures of the target compounds were confirmed by ^1H NMR, ^13C NMR, IR, and MS.

关键词： (R)- and (S)-Moprolol (R)- and (S)-Guaifenesin Asymmetric synthesis

Experimental system of coupled map lattices

在线全文

学校读者我要写书评

暂无评论

Frontiers of physics 2015年第3期10卷 101-104页

作者： Yu-Han Ma Lan-Qing Huang Chu-Min sun Xiao-wen li Department of Physics Beijing Normal University Beijing 100875 China

We design an optical feedback loop system consisting of a liquid-crystal spatial light modulator （SLM）, a lens, polarizers, a CCD camera, and a computer. The system images every SLM pixel onto one camera pixel. The light intensity on the camera pixel shows a nonlinear relationship with the phase shift applied by the SLM. Every pixel behaves as a nonlinear map, and we can control the interaction of pixels. Therefore, this feedback loop system can be regarded as a spatially extended system. This experimental coupled map has variable dimensions, which can be up to 512 by 512. The system can be used to study high-dimensional problems that computer simulations cannot handle.

关键词： coupled map lattices photoelectric feedback loop

Kinetics of Phosphatase of Regenerating liver-3(PRL-3) Inhibition by Small-molecular Inhibitors

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2006年第2期22卷 221-224页

作者： SHEN Xing-gui sun li-wen JIAO Ming li Zhao-fa ZHAO Zhi-zhuang li Qing-shan FU Xue-qi HUANG Zhong-xiu Edmond H. Fischer Signal Transduction Laboratory College of Life Sciences Jilin University Changchun 130021 P. R. China Qianwei Campus Clinical Hospital of Jilin University Changchun 130021 P. R. China

Phosphatase of Regenerating liver-3 （PRL-3） is a newly identified colorectal cancer metastasis-related protein, which is a 22 kDa non-classical protein tyrosine phosphatase with a C-terminal prenylation motif. In this study, the inhibition kinetics of protein tyrosine phosphatases（PTPs） by a fluorescent substrate, 6,8-difluoro-4-methylumbelliferyl phosphate（DiFMUP） was evaluated. PRL-3 exhibits classical Michaelis-Menten kinetics with a Vmax value of 11.3 μmol · L^-l · min^-1 Analysis of PRL-3 by a Michaelis-Menten plot and a double-reciprocal plot indicated that the inhibitor magnolol can cause Km to increase, but does not alter the Vmax value, which suggests the competitive inhibition of PRL-3. At the same time, it was found that DiFMUP is a more sensitive substrate for PRL-3 than para-nitrophenyl phosphate（pNPP） that is more frequently used at present. Furthermore, the method of screening for PTPs by the use of DiFMUP was developed, which studied the acceptance of DiFMUP by other PTPs.

关键词： PRL-3 DiFMUP Kinetics Inhibitor

Hyperlipidemia intensifies cerulein-induced acute pancreatitis associated with activation of protein kinase C in rats

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第18期12卷 2908-2913页

作者： Ya-Jun Wang Jia-Bang sun Fei li Shu-wen Zhang Department of General Surgery Xuanwu Hospital of Capital University of Medical Sciences Beijing 100053 China

AIM： To investigate the effects of hyperlipidemia on acute pancreatitis （AP） and the possible mechanisms. METHODS： Rat models of hyperlipidemia and AP were established by Triton WR1339 and cerulein respectively. Human albumin was used to treat AP complicated by hyperlipidemia. In each group, we compared the histological score, volume of ascites, ratio of pancreatic wet/dry weight, serum amylase （AMY） and pancreatic acinar cell apoptosis. The level of protein kinase C （PKC） membrane translocation in pancreatic tissue was detected by Western blot.RESULTS： In the hyperlipidemia model established by Triton WR1339, triglyceride （TG） increased remarkably and reached its peak 6 h after injection, and most rats developed mild acute pancreatitis. Histological score, volume of ascites, ratio of wet/dry weight and serum AMY in AP animals with hyperlipidemia were obviously higher than those in AP animals （P 〈 0.05） and decreased after albumin therapy but not significantly （P 〉 0.05）. Apoptotic cells detected by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling （TUNEL） increased in AP animals with hyperlipidemia and did not change distinctly after albumin therapy. PKC membrane translocation level increased in AP animals with hyperlipidemia and decreased remarkably after albumin therapy （P 〈 0.05）.CONCLUSION： Hyperlipidemia may induce AP or intensify pancreatic injury. Albumin therapy can not alleviate pancreatic lesion effectively. PKC activation may be one mechanism by which AP is intensified by hyperlipidemia.

关键词： Acute pancreatitis Hyperlipidemia Protein kinase C

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

超大跨斜拉桥多点振动台试验研究

工程力学 2016年第11期33卷 38-48页

作者：孙利民谢文同济大学土木工程防灾国家重点实验室上海200092 宁波大学建筑工程与环境学院浙江宁波315211

以一座试设计主跨1400 m斜拉桥为工程背景,进行了多点振动台阵试验。试验采用包括桩基础的1∶70缩尺模型,通过层状剪切土箱模拟场地土的作用,台阵包括4个振动台,可模拟非一致地震输入。研究了半漂浮体系、弹性约束体系和辅助墩体系等不... 详细信息

以一座试设计主跨1400 m斜拉桥为工程背景,进行了多点振动台阵试验。试验采用包括桩基础的1∶70缩尺模型,通过层状剪切土箱模拟场地土的作用,台阵包括4个振动台,可模拟非一致地震输入。研究了半漂浮体系、弹性约束体系和辅助墩体系等不同结构体系对斜拉桥纵向地震响应的影响;进而针对辅助墩体系,研究了上塔柱区段附加耗能构件对斜拉桥横向地震响应的影响;最后通过破坏性试验研究了斜拉桥的横向破坏模式及其灾变过程。结果表明:弹性拉索体系和辅助墩体系可有效减小主塔和塔-梁的纵向相对位移;附加的耗能构件对塔顶横向相对位移的减小效果有限,但可有效降低主塔应变响应,起分散主塔受力和附加耗能作用;主塔的横向破坏模式具有明显的双塑性铰模式。

关键词：超大跨斜拉桥多点振动台试验结构体系破坏模式耗能构件层状剪切变形土箱

维普期刊数据库博看期刊

Five "Mainstays" of Power Grid Innovation

在线全文

学校读者我要写书评

暂无评论

Electricity 2006年第4期17卷 22-25页

作者： By li Zhu sun wen li liancun liu Jing Wu Zhongjian Zhu Ye Journalist and Correspondents of State Grid

It is an important reason for Microsoft, Bell and General Electric etc dominating always on forward position in world's science and technologies to bring full play to auton- omous innovative capability of enterprises' research and development center. In the Power Grid Science and Technology Working Conference 2006, Mr. Lu Qizhou, the vice president of the State Grid Corporation(SG) pointed out that during the 11th Five-Year Plan period, the SG will emphatically push forward optimal conformity on scientific and technological resources among its affiliated research institutes, tap their back bone and leading effects in technical innovation system.

关键词：电网行业管理改革创新电力资源中国

黑龙江省农林用地确权和争议调处问题调查研究

在线全文

学校读者我要写书评

暂无评论

中国土地科学 2007年第4期21卷 71-73页

作者：孙文礼黑龙江省国土资源勘测规划院黑龙江哈尔滨150056

研究目的:研究黑龙江省农地与林地确权及权属纠纷案件的解决办法,为国家有关部门和黑龙江省政府决策提供客观依据。研究方法:文献资料法、实证分析法和理论研究法。研究结论:调整林区土地管理的相关法律关系;林地作为不动产其物权应实... 详细信息

研究目的:研究黑龙江省农地与林地确权及权属纠纷案件的解决办法,为国家有关部门和黑龙江省政府决策提供客观依据。研究方法:文献资料法、实证分析法和理论研究法。研究结论:调整林区土地管理的相关法律关系;林地作为不动产其物权应实行集中统一确权登记;细化现行的地权管理政策及措施;进一步强化各级政府土地权属管理的职能,增加地权争议特别是农林矛盾调处工作力量。

关键词：土地管理农地与林地确权权属纠纷解决办法