检索结果-南通市图书馆

Massive hemoptysis and hemothorax： a rare but fatal complication of intralobar sequestration

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2012年第14期125卷 2638-2640页

作者： WANG Hong-wei LU Jiang-yang sun jun-zhong, XIAO Yan WEN Bo Department of Patlaology First Affiliated Hospital of General Hospital of People's Liberation Army Beijing 100048 China Department of OncologyFirst Affiliated Hospital of General Hospital of People's Liberation Army Beijing 100048 China Respiratory Center First Affiliated Hospital of General Hospitalof People's Liberation Army Beijing 100048 China Department ofRadiology First Affiliated Hospital of General Hospitalof People's Liberation Army Beijing 100048 China

Intralobar sequestration （ILS） is an uncommon abnormality that accounts for 75% of all pulmonary sequestrations. Over the years there have been several reports of various presenting signs of which hemoptysis was commonly described, however, massive hemoptysis and hemothorax is extremely rare in literature. We present a case of a 45-year-old man who died of fatal complication from an ILS. This case report shows an uncommon presentation of ILS with massive hemoptysis and hemothorax resulting in a dramatic course of disease and a fatal outcome, and for this reason in the absence of trauma or other causes for massive hemoptysis, hemothorax, or lung hematoma, this possibility should be kept in mind so as to avoid misdiagnosis, and resection of the sequestered tissue should be considered in all patients.

关键词： hemoptysis hemothorax bronchopulmonary sequestration, autopsy

Cardiovascular computed tomography in cardiovascular disease:An overview of its applications from diagnosis to prediction

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2024年第5期21卷 550-576页

作者： zhong-Hua sun Discipline of Medical Radiation Science Curtin Medical SchoolCurtin UniversityPerthAustralia Curtin Health Innovation Research Institute(CHIRI) Curtin UniversityPerth 6012Australia

Cardiovascular computed tomography angiography(CTA)is a widely used imaging modality in the diagnosis of cardiovascular *** in CT imaging technology have further advanced its applications from high diagnostic value to minimising radiation exposure to *** addition to the standard application of assessing vascular lumen changes,CTA-derived applications including 3D printed personalised models,3D visualisations such as virtual endoscopy,virtual reality,augmented reality and mixed reality,as well as CT-derived hemodynamic flow analysis and fractional flow reserve(FFRCT)greatly enhance the diagnostic performance of CTA in cardiovascular *** widespread application of artificial intelligence in medicine also significantly contributes to the clinical value of CTA in cardiovascular *** value of CTA has extended from the initial diagnosis to identification of vulnerable lesions,and prediction of disease extent,hence improving patient care and *** this review article,as an active researcher in cardiovascular imaging for more than 20 years,I will provide an overview of cardiovascular CTA in cardiovascular *** is expected that this review will provide readers with an update of CTA applications,from the initial lumen assessment to recent developments utilising latest novel imaging and visualisation *** will serve as a useful resource for researchers and clinicians to judiciously use the cardiovascular CT in clinical practice.

关键词： diagnosis cardiovascular prediction

Reversal of multidrug resistance in renal cell carcinoma by short hairpin RNA targeting MDR1 gene

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2012年第15期125卷 2741-2745页

作者： HAO Yi-xin HE Zheng-wen ZHU Jian-hua SHEN Qian sun jun-zhong DU Nan XIAO Wen-hua Department of Oncology First Affiliated Hospital of the People'sLiberation Army General Hospital Beijing 100048 China Department of Laboratory Diagnosis Claanghai Hospital SecondMilitary Medical University Shanghai 200433 China

Background Over-expression of P-glycoprotein （P-gp）, encoded by the MDR1 gene, confers multidrug resistance （MDR） in renal cell carcinoma （RCC） and is a major reason for unsuccessful chemotherapy. This study aimed to determine the effct of RNA interference （RNAi） on the reversal of MDR in human RCC. Methods We designed and selected one short hairpin RNA （shRNA） targeting MDR1 gene, which is stably expressed from integrated plasmid and transfected by lentivirus fluid in human RCC A498 cell. Results The MDRl-targeted RNAi resulted in decreased MDR1 gene mRNA level （P 〈0.001）, almost abolished P-gp expression and reversed MDR to different chemotherapy drugs in the RCC A498 cell line. Conclusion MDR could be reversed by RNAi in human RCC A498 cell line, which may be used for clinical application

关键词： multidrug resistance, P-glycoprotein short hairpin RNA renal cell carcinoma

Chiral phonon activated spin Seebeck effect in chiral materials

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2024年第3期67卷 149-155页

作者： Xiao Li Jinxin zhong Jinluo Cheng Hao Chen Huiqian Wang jun Liu Dali sun Lifa Zhang jun Zhou Phonon Engineering Research Center of Jiangsu Province Center for Quantum Transport and Thermal Energy ScienceSchool of Physics and TechnologyNanjing Normal UniversityNanjing 210023China Center for Phononics and Thermal Energy Science China-EU Joint Lab for NanophononicsSchool of Physics Science and EngineeringTongji UniversityShanghai 200092China Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of ScienceChangchun 130033China Department of Mechanical and Aerospace Engineering North Carolina State UniversityRaleigh NC 27606USA Department of Physics North Carolina State UniversityRaleigh NC 27695USA Organic and Carbon Electronics Laboratories(ORaCEL) North Carolina State UniversityRaleigh NC 27606USA

Efficient generation of spin polarization is very important for spintronics and quantum computation. In chiral materials without magnetic order nor spin-orbit coupling, we find a new spin selectivity effect—chiral phonon activated spin Seebeck(CPASS)effect. Starting with the nonequilibrium distribution of chiral phonons under a temperature gradient, the CPASS coefficients are computed based on the Boltzmann transport theory. With both the phonon-drag and band transport contributions, the spin accumulations generated by the CPASS effect exhibit quadratic dependence on the temperature gradient. The strength of the CPASS effect and the relative magnitude of both contributions are tunable by the chemical potential modulation. The CPASS effect, which gives a promising explanation on the traditional chiral-induced spin selectivity effect, provides opportunities for the exploration of advanced spintronic devices based on chiral materials even in the absence of any magnetic order and spin-orbit coupling.

关键词： spin Seebeck effect chiral phonon phonon-drag contribution efficient spin generation

Phase behavior of gas condensate in porous media using real-time computed tomography scanning

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2024年第2期21卷 1032-1043页

作者： Wen-Long Jing Lei Zhang Ai-Fen Li jun-Jie zhong Hai sun Yong-Fei Yang Yu-Long Cheng jun Yao Institute of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongChina National Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)Qingdao266580ShandongChina

The phase behavior of gas condensate in reservoir formations differs from that in pressure-volume-temperature(PVT)cells because it is influenced by porous media in the reservoir *** was used as a sample to investigate the influence of porous media on the phase behavior of the gas *** pore structure was first analyzed using computed tomography(CT)scanning,digital core technology,and a pore network *** sandstone core sample was then saturated with gas condensate for the pressure depletion *** each pressure-depletion state was stable,realtime CT scanning was performed on the *** scanning results of the sample were reconstructed into three-dimensional grayscale images,and the gas condensate and condensate liquid were segmented based on gray value discrepancy to dynamically characterize the phase behavior of the gas condensate in porous *** network models of the condensate liquid ganglia under different pressures were built to calculate the characteristic parameters,including the average radius,coordination number,and tortuosity,and to analyze the changing mechanism caused by the phase behavior change of the gas *** types of condensate liquid(clustered,branched,membranous,and droplet ganglia)were then classified by shape factor and Euler number to investigate their morphological changes dynamically and *** results show that the dew point pressure of the gas condensate in porous media is 12.7 MPa,which is 0.7 MPa higher than 12.0 MPa in PVT *** average radius,volume,and coordination number of the condensate liquid ganglia increased when the system pressure was between the dew point pressure(12.7 MPa)and the pressure for the maximum liquid dropout,Pmax(10.0 MPa),and decreased when it was below *** volume proportion of clustered ganglia was the highest,followed by branched,membranous,and droplet *** study provides crucial experimental evidence for the phase behavior chan

关键词： Gas condensate Pressure depletion Real-time micro-computed tomography scanning Distribution of condensate liquid

Pretreating and normalizing metabolomics data for statistical analysis

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第3期11卷 188-205页

作者： jun sun Yinglin Xia Division of Gastroenterology and Hepatology Department of MedicineDepartment of Microbiology/ImmunologyUIC Cancer CenterUniversity of Illinois ChicagoJesse Brown VA Medical Center Chicago(537)ChicagoIL 60612USA Division of Gastroenterology and Hepatology Department of MedicineUniversity of Illinois ChicagoChicagoIL 60612USA

Metabolomics as a research field and a set of techniques is to study the entire small molecules in biological *** is emerging as a powerful tool generally for pre-cision ***,integration of microbiome and metabolome has revealed the mechanism and functionality of microbiome in human health and ***,metabo-lomics data are very ***/pretreating and normalizing procedures on metabolomics data are usually required before statistical *** this review article,we comprehensively review various methods that are used to preprocess and pretreat metabolo-mics data,including MS-based data and NMR-based data preprocessing,dealing with zero and/or missing values and detecting outliers,data normalization,data centering and scaling,data *** discuss the advantages and limitations of each *** choice for a suitable preprocessing method is determined by the biological hypothesis,the characteristics of the data set,and the selected statistical data analysis *** then provide the perspective of their applications in the microbiome and metabolome research.

关键词： Data centering and scaling Data normalization Data transformation Missing values MS-Baseddata preprocessing NMRData preprocessing Outliers Preprocessing/pretreatment

Operational Characteristics of Loop Heat Pipe in Microgravity and Normal Gravity Environments

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2024年第4期33卷 1394-1408页

作者： zhong Siyuan XIE Rongjian LI Yunfei sun Xiaojin Shanghai Institution of Technology and Physics Shanghai200083China University of Chinese Academy of Sciences Beijing100049China Shanghai Institute of Satellite Engineering Shanghai200240China

The loop heat pipe(LHP)is an advanced,efficient two-phase heat transfer unit,whose operational performance may be affected by microgravity conditions in contrast to ground-based *** performance of on-orbit temperature data and ground test of a copper-propylene LHP with a condenser temperature range of 243.15 K to 303.15 K were employed to compared and *** LHP has successfully started up for more than 193 times with a good heat transfer performance and a stable start-up stabilization on-orbit under a complex orbital heating environment for more than eight *** a small heat load(10.0W),the average start-up time is 110.0 s while the start-up temperature ranges from 5.71 K-12.78 *** start-up time at large temperature differences in the high temperature zone will be higher than the time required for start-up at smaller temperature differences in the low *** the condenser temperature is 250.0 K,the stable temperature difference on orbit is 3.83 K,which is generally consistent in heat transfer compared to 2.20 K in the ground *** this paper,we can conclude that the on-orbit flight data up to now can provide a reference to the design of subsequent LHP space applications.

关键词： Loop Heat Pipe(LHP) start up microgravity on-orbit experiment

Passivity-Based Stabilization for Switched Stochastic Nonlinear Systems

在线全文

学校读者我要写书评

暂无评论

IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1307-1309页

作者： Yaowei sun jun Zhao School of Automation Zhengzhou University of AeronauticsZhengzhou 450046 Henan Key Laboratory of General Aviation Technology Zhengzhou University of AeronauticsZhengzhou 450046China College of Information Science and Engineering Northeastern UniversityShenyang 110819China

Dear Editor,This letter addresses the passivity-based mean square exponential stabilization problem for switched stochastic nonlinear systems.A concept of generalized small-time norm-observability is presented and an appropriate test condition is also *** pre-given passivity rate and average dwell time,a set of feedback controllers is designed by use of the passivity property.

关键词： property letter stabilization

Metabolites and micronutrition in modulating amyotrophic lateral sclerosis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第6期19卷 1183-1184页

作者： Katerina Claud jun sun Department of Medicine University of Illinois Chicago Jesse Brown VA Medical Center Chicago

Amyotrophic lateral sclerosis(ALS) is a progressive neurodegenerative disease. The majority of ALS cases are sporadic with only about 20% of familial forms. Even in families with genetic predisposition, there is significant phenotypic variability, suggesting that ALS onset may be triggered by a combination of genetic factors, environmental factors(e.g., military service,

关键词：