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Comparative analysis of volatile oils in the stems and roots of Ephedra sinica via GC-MS-based plant metabolomics

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Chinese Journal of Natural Medicines 2016年第2期14卷 133-140页

作者： LV Meng-Ying sun jian-bo WANG Min FAN Hong-Yan ZHANG Zun-jian XU Feng-Guo Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education) China Pharmaceutical University State Key Laboratory of Natural Medicine China Pharmaceutical University Department of Natural Medicinal Chemistry China Pharmaceutical University

With a great difference in therapeutic effects of Mahuang(MH, the stems of Ephedra sinica) and Mahuanggen(MHG, the roots of Ephedra sinica), chemical differences between MH and MHG should be investigated. In the present study, gas chromatography-mass spectrometry(GC-MS)-based plant metabolomics was employed to compare volatile oil profiles of MH and MHG. The antioxidant activities of volatile oils from MH and MHG were also compared. 32 differential chemical markers were identified according to the variable importance in the projection(VIP) value of orthogonal partial least squares discriminant analysis(OPLS-DA) and P value of Mann-Whitney test. Among them, chemical markers of tetramethylpyrazine(TMP) and α-terpineol were quantified. Their contents were much higher in most MH samples compared with MHG. The antioxidant assay demonstrated that MH had significantly higher free radical-scavenging activity than MHG. Although MH and MHG derived from the same medicinal plant, there was much difference in their volatile oil profiles. MH samples had significantly higher content of two reported pharmacologically important chemical markers of TMP and α-terpineol, which may account for their different antioxidant activities.

关键词： Ephedra sinica GC-MS Volatile oil Plant metabolomics Antioxidant activity

Initial Descent Phase Guidance for Hypersonic Glide vehicle 36

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Initial Descent Phase Guidance for Hypersonic Glide vehicle

Design and Application of Simulation for Controllable Pitch Propeller Hydraulic Servo System 36

第36届中国控制会议

作者： sun jian-bo Pan Xing-hua Zhao Yu-shan School of Astronautics Beihang University Beijing Electro-mechanical Engineering Institute

ISBN: (纸本)9781538629185

A novel initial descent guidance law based on the transition function is proposed for the hypersonic glide vehicle without offline nominal angle of attack（AOA） design and online iteration *** the variation of the gravitational acceleration,a new transition condition between the initial descent phase and the quasi-equilibrium glide phase is ***,the initial descent phase is divided into two sub-phases noted as the open-loop guidance phase and the transition scheme *** guidance command during the transition scheme phase is generated by transition functions firstly proposed in this paper,which can smoothly adjust the AOA to satisfy the transition *** simulation results show that the proposed guidance law can satisfy the transition condition and the path constraints.

关键词： Hypersonic glide vehicle quasi-equilibrium glide initial descent guidance transition function

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Design and Application of Simulation for Controllable Pitch ...

A new quinoline alkaloid from the roots of Dictamnus angustifolius

第36届中国控制会议

作者： Zhang Hui sun jian-bo Li Ying Huang Yong-feng Academy of Marine Engineering Dalian Maritime University Academy of Information Science and Technology Dalian Maritime University

ISBN: (纸本)9781538629185

In order to solve the problems that hydraulic servo system of the controllable pitch propeller is limited by the environment in actual trainings and high maintenance costs,on the basis of process simulation support platform,a hydraulic servo software simulation system of the controllable pitch propeller will be ***,mathematical models of hydraulic system pipe network,pump valve,hydraulic cylinder,cooler,and the propeller pitch actuator will be established;secondly,the simulation of the system logic control interface will be realized by VC++ programming technique;finally,the software simulation system will be provided with the whole operating functions of hydraulic system of the controllable pitch propeller and simulate the malfunctions in real ship to make assessments *** could simulate the malfunctions in real ship system and be useful in the education and training of mariners.

关键词： Controllable-pitch propeller Mathematical model Intelligent evaluation Simulation teaching

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Chinese Journal of Natural Medicines 2014年第3期12卷 222-224页

作者： sun jian-bo QU Wei GUAN Fu-Qin LI Lin-Zhen LIANG Jing-Yu Department of Natural Medicinal Chemistry China Pharmaceutical University Institute of botany Jiangsu Province and Chinese Academy of Science

AIM： To investigate the quinoline alkaloids from the roots ofDictamnus angustifolius *** ex Sweet （Rutaceae）. METHOD： The quinoline alkaloids were isolated by various column chromatographic methods and their structures were eluci- dated on the basis of spectral analysis. RESULTS： A new quinoline alkaloid, 5-methoxylrobustine （1）, along with five known quinoline alkaloids were obtained, and their structures were identified as dictamnine （2）, robustine （3）, isopteleine （4）, 7-fagarine （5）, and skimmianine （6）. Cytotoxicity testing of these alkaloids showed that all of them had weak cytotoxic activities against human breast cancer cells （MCF7）. CONCLUSION： Compound 1 is a new quinoline alkaloid. Alkaloid 3 showed stronger anti-proliferation effect than the other al- kaloids.

关键词： Dictamnus angustifolius Quinoline alkaloids 5-Methoxylrobustine Cytotoxicity

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大型低速二冲程柴油机动力装置的准稳态仿真

内燃机学报 2006年第4期24卷 351-356页

作者：孙建波郭晨大连海事大学自动化与电气工程学院辽宁大连116026

利用准稳态、循环平均值等建模方法,给出了包含大型低速二冲程柴油机、轴系、螺旋桨和船体动力学的实时仿真模型。在螺旋桨特性计算中,提出了推力系数和转矩系数计算的简便算法,算法既能避免利用螺旋桨图谱的复杂计算过程,又能满足全工... 详细信息

利用准稳态、循环平均值等建模方法,给出了包含大型低速二冲程柴油机、轴系、螺旋桨和船体动力学的实时仿真模型。在螺旋桨特性计算中,提出了推力系数和转矩系数计算的简便算法,算法既能避免利用螺旋桨图谱的复杂计算过程,又能满足全工况范围的仿真需要。仿真程序是利用VC++开发实现的。仿真结果表明,动力装置在稳态和变工况下的计算结果与实船试航数据能够较好的吻合。螺旋桨特性计算的简便算法可以应用于螺旋桨特性的分析和建模,仿真模型可用于动力装置的性能分析、预测和调速器系统的设计和优化。

关键词：船用柴油机准稳态仿真建模动力装置系统螺旋桨特性

Simulation Training System of Marine Auxiliary boiler and Its Application

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Simulation Training System of Marine Auxiliary Boiler and It...

Numerical Simulation of the Electromagnetic Continuous Casting for Clad Slab

第30届中国控制与决策会议

作者： AI Fu-cheng sun jian-bo College of Marine Engineering Dalian Maritime University College of Information Science and Technology Dalian Maritime University

At present, the auxiliary boiler simulation training system is still imperfect, and the realization of some functions and operations is relatively simple. Therefore, based on the marine engine simulation platform of Dalian Maritime University, this paper combined the existing intelligent assessment examination system, perfected boiler simulation training system, carried out system modeling, and the system model was put into the simulation platform. The system can be used for trainees’ training. We can simulate a fault by changing some parameters, and by some operation of interface, these parameters can return to normal. Thus, we can achieve the goal of training engineers’ ability to analyze and solve the system fault.

关键词： Auxiliary boiler Simulation Training System

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Journal of Iron and Steel Research International 2012年第S1期19卷 153-157页

作者： YU Ying-shui WANG Tong-min sun jian-bo JIE Jin-chuan CAO Zhi-qiang LI Ting-ju School of Materials Science and Engineering Dalian University of Technology School of Materials Science and Engineering Jiamusi University

In this paper,a new electromagnetic continuous casting process to prepare clad slab is *** influence of level direct current electromagnetic field on temperature and flow fields of the melt during the fabrication of clad slab were numerically studied by the engineering software ANSYS and *** results indicated that when the magnetic flux density(B)was 0.15 T,the impact velocity and distance of the flow to the narrow face and underside of the dividing plate decreased *** the flow impact to the liquid pool was *** the same time,the high temperature zone of the melt moved away from the narrow face and the dividing plate,and distributed more uniformly. The wider semi-solid area next to the dividing plate was useful for 3003 and 4004 aluminum alloys to bond.

关键词： clad slab electromagnetic continuous casting numerical simulation

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股价信号、项目价值与公司投资行为选择

南京师大学报（社会科学版） 2007年第2期 63-68页

作者：孙建波南京大学经济学系江苏南京210093

资本市场和实体经济之间存在密切关系,资本市场资源配置效率决定了股价信号与公司投资的关系。将股价信号、项目价值与公司投资纳入一个统一的框架体系,利用逐步回归方法,对我国长江三角洲地区制造业上市公司资料的实证检验表明,股价信... 详细信息

资本市场和实体经济之间存在密切关系,资本市场资源配置效率决定了股价信号与公司投资的关系。将股价信号、项目价值与公司投资纳入一个统一的框架体系,利用逐步回归方法,对我国长江三角洲地区制造业上市公司资料的实证检验表明,股价信号对公司投资决策有一定的影响,在我国目前信息不对称、市场投机严重等不完全市场的条件下,对公司投资会产生过度的激励。

关键词：股价信号项目价值投资行为选择

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船舶机舱监测和报警系统的设计与实现

系统仿真学报 2006年第Z2期18卷 851-853,856页

作者：孙建波郭晨张旭大连海事大学自动化与电气工程学院大连116026

机舱检测和报警系统是现代化船舶自动化机舱的重要组成部分,针对国内部分船舶机舱检测和报警系统产品在功能和显示模式方面都无法完全满足自动化机舱发展的需要等缺点,采用了VC++可视化建模、数据库、网络等技术,设计和开发了船舶机舱... 详细信息

机舱检测和报警系统是现代化船舶自动化机舱的重要组成部分,针对国内部分船舶机舱检测和报警系统产品在功能和显示模式方面都无法完全满足自动化机舱发展的需要等缺点,采用了VC++可视化建模、数据库、网络等技术,设计和开发了船舶机舱监测和报警系统。该系统具有网络化和模块化结构,检测和报警采样点共735个,覆盖了机舱所有重要设备。为了简化系统结构和降低硬件成本,监测、报警、操作和控制功能全部由软件实现。仿真试验表明,系统的功能完善,显示模式多样化,有利于进行故障预测和诊断,也为船舶维修提供了较为充分的综合数据信息。该系统已经作为新一代大型船舶轮机模拟器的仿真子系统投入应用。

关键词：船舶动力装置机舱监测系统报警系统