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Transplantation of human placental chorionic plate-derived mesenchymal stem cells for repair of neurological damage in neonatal hypoxic-ischemic encephalopathy

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Neural Regeneration Research 2024年第9期19卷 2027-2035页

作者： Lulu Xue Ruolan Du Ning Bi Qiuxia Xiao yifei sun Ruize Niu Yaxin Tan Li Chen Jia Liu Tinghua Wang Liulin Xiong Transformation Research Laboratory The Affiliated Hospital of Zunyi Medical UniversityZunyiGuizhou ProvinceChina State Key Laboratory of Biotherapy Sichuan UniversityChengduSichuan ProvinceChina Institute of Neurological Disease Translational Neuroscience CenterWest China HospitalSichuan UniversityChengduSichuan ProvinceChina Department of Animal Zoology Institute of NeuroscienceKunming Medical UniversityKunmingYunnan ProvinceChina Department of Anesthesiology The Affiliated Hospital of Zunyi Medical UniversityZunyiGuizhou ProvinceChina Department of Pediatrics the People’s Liberation Army Rocket Force Characteristic Medical CenterBeijingChina

Neonatal hypoxic-ischemic encephalopathy is often associated with permanent cerebral palsy,neurosensory impairments,and cognitive deficits,and there is no effective treatment for complications related to hypoxic-ischemic *** therapeutic potential of human placental chorionic plate-derived mesenchymal stem cells for various diseases has been ***,the potential use of human placental chorionic plate-derived mesenchymal stem cells for the treatment of neonatal hypoxic-ischemic encephalopathy has not yet been *** this study,we injected human placental chorionic plate-derived mesenchymal stem cells into the lateral ventricle of a neonatal hypoxic-ischemic encephalopathy rat model and observed significant improvements in both cognitive and motor *** chip analysis showed that interleukin-3 expression was significantly elevated in neonatal hypoxic-ischemic encephalopathy model *** transplantation of human placental chorionic plate-derived mesenchymal stem cells,interleukin-3 expression was *** further investigate the role of interleukin-3 in neonatal hypoxic-ischemic encephalopathy,we established an in vitro SH-SY5Y cell model of hypoxic-ischemic injury through oxygen-glucose deprivation and silenced interleukin-3 expression using small interfering *** found that the activity and proliferation of SH-SY5Y cells subjected to oxygen-glucose deprivation were further suppressed by interleukin-3 ***,interleukin-3 knockout exacerbated neuronal damage and cognitive and motor function impairment in rat models of hypoxic-ischemic *** findings suggest that transplantation of hpcMSCs ameliorated behavioral impairments in a rat model of hypoxic-ischemic encephalopathy,and this effect was mediated by interleukin-3-dependent neurological function.

关键词： behavioral evaluations gene knockout human neuroblastoma cells(SH-SY5Y) human placental chorionic derived mesenchymal stem cells interleukin-3 neonatal hypoxic-ischemic encephalopathy nerve injury oxygen-glucose deprivation protein chip small interfering RNA

Dynamic tracking of exsolved PdPt alloy/perovskite catalyst for efficient lean methane oxidation

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Chinese Chemical Letters 2024年第4期35卷 170-175页

作者： Yanling Yang Zhenfa Ding Huimin Wang Jianhui Li Yanping Zheng Hongquan Guo Li Zhang Bing Yang Qingqing Gu Haifeng Xiong yifei sun College of Energy Xiamen UniversityXiamen 361005China School of Environment and Civil Engineering Dongguan University of TechnologyDongguan 523808China Department of Chemistry College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China CAS Key Laboratory of Science and Technology on Applied Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361102China

Supported Pd based catalysts are considered as the efficient candidates for low-carbon alkane oxidation for their outstanding capability to break C-H bond. Whereas, the irreversible deactivation of Pd based catalysts was still frequently observed. Herein, we reinforced the extruded Pd nanoparticles with quantitive Pt to assemble the evenly distributed Pd Pt nanoalloy onto ferrite perovskite(Pd Pt-LCF) matrix with strengthened robustness of metal/oxide support interface. We further co-achieved the enhanced performance, anti-overoxidation as well as resistance of vapor-poisoning in durability measurement. The operando X-ray photoelectron spectroscopy(O-XPS) combined with various morphology characterizations confirms that the accumulation of surface deep-oxidation species of Pd^(4+) is the culprit for fast activity loss in exsolved Pd system, especially at high temperature of 400 ℃. Conversely, it could be completely suppressed by in-situ alloying Pd with equal amount of Pt, which helps maintain the metastable Pd^(2+)/Pd shell and metallic solid-solution core structure. The density function theory(DFT) calculations further buttress that the dissociation of C–H was facilitated on alloy/perovskite interface which is, on the contrary, resistant toward O–H bond cleavage, as compared to Pd/perovskite. Our work suggests that the modification of exsolved metal/oxide catalytic interface could further enrich the toolkit of heterogeneous catalyst design.

关键词： Exsolution PdPt alloy Operando characterization Methane conversion Deep-oxidation

Different agricultural practices specify bacterial community compositions in the soil rhizosphere and root zone

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Soil Ecology Letters 2022年第1期4卷 18-31页

作者： Yan Wang Guowei Chen yifei sun Kun Zhu Yan Jin Baoguo Li Gang Wang Department of Water&Soil Sciences China Agricultural UniversityBeijing 100193China Department of Civil Engineering Hefei University of TechnologyHefei 230009China Department of Plant&Soil Sciences University of DelawareNewarkDE 19716USA

We are only beginning to understand the influence of agricultural practices,together with soil properties and geographic factors,affect bacterial communities and their influence on the soil ***,we quantify how typical agro-practices,i.e.,no-tillage,ridge tillage,continuous corn cropping,and crop rotation with corn and bean,and the corresponding soil physicochemical characteristics affect bacterial diversity and community compositions of the rhizosphere and root zone *** show that species richness in the rhizosphere was significantly higher than that in the root zone soils(p<0.05),typically with more abundant Crenarchaeota and Firmicutes populations that are active members for C and N ***,crop rotation compared to other agro-practices was able to mediate soil pH value and the available P and thereby control the bacterial diversity pattern in the rhizosphere(p<0.05),while tillage practices regulated the relative abundance of bacterial populations in root zone soils by varying the soil available N(p<0.05).Analysis of biomarker patterns suggests that the observed differences in bacterial functional capabilities(e.g.,nutrient cycling)are strongly related to the physicochemical properties of surrounding *** results highlight the importance of soil-plant interaction in shaping soil bacterial community structure typically in the rhizosphere and root zone soils and also illustrates the challenges in linking soil ecosystem function to microbial processes.

关键词： Next generation sequencing Agro-practices Bacterial community Rhizosphere

Numerical Simulation of Self-excited Oscillation Switching Current in HVDC MRTB

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高电压技术 2013年第10期39卷 2547-2552页

作者： LI Yang YANG Fei RONG Mingzhe WU Yi WU yifei sun Hao State Key Laboratory of Electrical Insulation and Power Equipment School of Electrical Engineering Xi'an Jiaotong University Xi'an 710049 China

This paper presents a numerical study of the current self-excited oscillations during the opening of high voltage direct current(HVDC) metallic return transfer breaker(MRTB).The switching arc is simulated using the magneto-hydrodynamics(MHD) theory coupled with the electric circuit *** simulation is proved accurate in simulating the current oscillation and the commutation process in MRTB by the good agreement between the calculated results and the experimental results,which are obtained on a MRTB prototype designed to break about 5 kA of DC *** kinds of the results show that the current oscillation starts at about 16.5 ms and the total arc time is about 24 ms with a commutation capacitor bank of 72 μF and an inductor of 173 μ*** a further analyze on how circuit parameters influence arc current oscillations,this study helps to improve the current interruption capability of MRTB.

关键词：双筒望远镜数值模拟自激振荡直流输电开关电流热感应磁流体动力学开关电弧

Gas diffusion in catalyst layer of flow cell for CO_(2) electroreduction toward C_(2+) products

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Nano Research 2024年第3期17卷 1101-1106页

作者： Xiqing Wang Qin Chen Yajiao Zhou Yao Tan Ye Wang Hongmei Li Yu Chen Mahmoud Sayed Ramadan A.Geioushy Nageh K.Allam Junwei Fu yifei sun Min Liu Hunan Joint International Research Center for Carbon Dioxide Resource Utilization School of Physics and ElectronicsCentral South UniversityChangsha 410083China School of Energy and Power Engineering Beihang UniversityBeijing 100191China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450002China Central Metallurgical Research and Development Institute(CMRDI) P.O.Box 87Helwan 11421CairoEgypt Energy Materials Laboratory School of Sciences and EngineeringThe American University in CairoNew Cairo 11835Egypt Research Center for Advanced Energy and Carbon Neutrality Beihang UniversityBeijing 100191China

The use of gas diffusion electrode(GDE)based flow cell can realize industrial-scale CO_(2) reduction reactions(CO_(2)RRs).Controlling local CO_(2) and CO intermediate diffusion plays a key role in CO_(2)RR toward multi-carbon(C_(2+))*** this work,local CO_(2) and CO intermediate diffusion through the catalyst layer(CL)was investigated for improving CO_(2)RR toward C_(2+)*** gas permeability tests and finite element simulation results indicated CL can balance the CO_(2) gas diffusion and residence time of the CO intermediate,leading to a sufficient CO concentration with a suitable CO_(2)/H_(2)O supply for high C_(2+)*** a result,an excellent selectivity of C_(2+)products~79%at a high current density of 400 mA·cm^(-2) could be obtained on the optimal 500 nm Cu CL(Cu500).This work provides a new insight into the optimization of CO_(2)/H_(2)O supply and local CO concentration by controlling CL for C_(2+)products in CO_(2)RR flow cell.

关键词： gas diffusion electrode CO_(2)reduction Cu mass transfer C_(2)product

Characterization of Passive Film Formed on 304 SS in Simulated Alkaline Water Chemistries Containing Sulfur at 300℃

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Transactions of Tianjin University 2015年第6期21卷 554-561页

作者：夏大海孙毅飞范洪强 Tianjin Key Laboratory of Composite and Functional Materials Tianjin University Department of Chemical and Materials Engineering University of Alberta School of Materials Science and Engineering Tianjin University

Passivity degradation of 304 stainless steel(SS) in simulated alkaline water chemistries at 300℃ was investigated using polarization curve, scanning electron microscope, time-of-flight secondary ion mass spectrometry(SIMS) and X-ray photoelectron spectroscopy(XPS). Experimental results indicated that 304,SS was selfpassive in the test solution and the thickness of passive film was about 500 nm. Hydroxide was enriched in the outer layer whereas oxide was enriched in the inner layer. Sulfur in thiosulfate could be reduced into lower valence of sulfur and enter the passive film so that the composition of passive film was modified by sulfur. Fe and Cr were enriched in the passive film whereas Ni was depleted in the passive film.

关键词： passive film 304 stainless steel thiosulfate SIMS polarization curve

The inflection point about COVID-19 may have passed

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Science Bulletin 2020年第11期65卷 865-867,M0003页

作者： Chaolin Gu Jie Zhu yifei sun Kai Zhou Jiang Gu School of Architecture Tsinghua UniversityBeijing 100085China Jiangsu Branch of China Academy of Urban Planning and Design Nanjing 210000China Department of Geography and Environmental Studies California State University NorthridgeInternational Institute for Innovation and Development(I3D)NorthridgeCA 91326USA School of Architecture Hunan UniversityChangsha 4W082China Hubei Provincial Key Laboratory for Geographical Process Analysis and Simulation Academy of Wuhan Metropolitan AreaCollege of Urban and Environmental ScienceCentral China Normal UniversityWuhan 430079China

In an era of globalization and informatisation,a Public Health Emergency of International Concern(PHEIC)imposes a huge impact on everyone’s life[1],as what the COVID-19 has demonstrated at the *** China’s nationwide quarantine and extremely strict epidemic prevention measures,it becomes increasingly critical for China and the world to know the evolving trend,though unclear yet,for the sake of the global *** is mainly due to the following two important reasons[2].First of all,because of the quarantine,a sudden shutdown of manufacturing in China(now the second largest economy of the world)would break the global supply chain,with the potential to eliminate China’s current advantageous ***,many small enterprises in the service industry are facing death or life situation with the spreading disease,and many will bankrupt[3].When the inflection point of the COVID-19 epidemic appears suddenly becomes a critical issue for China and the world.

关键词： nationwide everyone suddenly

心理-日常生活史研究的杰作——评《与巫为邻:欧洲巫术的社会和文化语境》

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史学理论研究 2007年第1期 144-147页

作者：孙义飞东北师范大学历史文化学院世界文明史研究中心博士生130024

牛津万圣学院资深学者罗宾·布里吉斯（Robin Briggs）长期致力于欧洲近代早期史研究，是当今研究欧洲近代早期宗教、流行文化和巫术问题的知名专家。《与巫为邻》汇其多年心血，以其对欧洲近代早期社会，尤其是对巫术问题和民众心理、... 详细信息

牛津万圣学院资深学者罗宾·布里吉斯（Robin Briggs）长期致力于欧洲近代早期史研究，是当今研究欧洲近代早期宗教、流行文化和巫术问题的知名专家。《与巫为邻》汇其多年心血，以其对欧洲近代早期社会，尤其是对巫术问题和民众心理、日常生活状态的深刻阐释，自1996年问世伊始即成为该领域典范之作。第二版更在前版基础上进行了精心修改，成为研究欧洲近代早期史者不可规避的重要著作。

关键词：民众心理欧洲文化语境巫术社会生活史近代早期流行文化

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堆石料的三维应力分数阶本构模型

土木与环境工程学报（中英文） 2022年第4期44卷 27-34页

作者：吉华孙逸飞中国电建集团华东勘测设计研究院杭州310014 河海大学土木与交通学院南京210098 德国波鸿鲁尔大学土木与环境工程学院波鸿44801

为合理反映粗粒土的状态依赖非关联应力应变特性,提出应力分数阶塑性力学模型。已有模型基于三轴试验结果,无法对堆石料真三轴条件下的应力应变特性进行预测,为解决这一问题,基于特征应力法对已有分数阶塑性力学模型进行完善。进一步选... 详细信息

为合理反映粗粒土的状态依赖非关联应力应变特性,提出应力分数阶塑性力学模型。已有模型基于三轴试验结果,无法对堆石料真三轴条件下的应力应变特性进行预测,为解决这一问题,基于特征应力法对已有分数阶塑性力学模型进行完善。进一步选取不同初始状态条件下堆石料的真三轴压缩试验数据对模型进行验证,结果表明,三维化后的分数阶岩土塑性力学模型可以合理地模拟不同初始状态的堆石料在真三轴压缩条件下的应力应变行为。与传统塑性力学模型相比,提出的分数阶塑性模型在描述堆石料非关联流动时不需要额外引入塑性势函数,仅需对已有屈服面求解分数阶导数。此外,模型在特征应力空间中推导完成再映射到原应力空间,可描述土体的三维强度特性,无需额外采用三维强度准则。

关键词：堆石料三维应力塑性力学分数阶微积分状态参数本构模型

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