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空间机械臂运动控制的地面仿真验证技术

南京航空航天大学学报 2022年第1期54卷 58-67页

作者：刘茜刘传凯朱安谢珊珊吴杰孙军张楠曾晓旭张宽张济韬李立春北京航天飞行控制中心北京100094 航天飞行动力学技术重点实验室北京100094 福州大学机械工程及自动化学院福州350108 航天系统部北京100080 北京邮电大学现代邮政学院(自动化学院) 北京100876

空间机械臂是在轨进行舱外巡检、航天员辅助出舱的关键活动机构,其在轨操作的运动过程需要在地面进行预先规划生成运动控制指令,再通过数字仿真与推演对运动控制指令进行验证,以确保机械臂操作全程的安全性和高效性。针对上述问题,本文... 详细信息

空间机械臂是在轨进行舱外巡检、航天员辅助出舱的关键活动机构,其在轨操作的运动过程需要在地面进行预先规划生成运动控制指令,再通过数字仿真与推演对运动控制指令进行验证,以确保机械臂操作全程的安全性和高效性。针对上述问题,本文主要从运动空间限制、运动速度限制和关节力矩限制等方面设计了地面仿真验证框架,提出了基于运动学与动力学建模、运动空间与碰撞关系分析的仿真验证策略,给出了关节运动、关节力矩和碰撞安全距离的计算方法以及超限检测与风险判断的准则,最后通过对关节超限检测、速度超限检测、力矩超限检测、碰撞检测与风险预估的仿真实验,证明了空间机械臂运动控制的地面仿真验证方法的有效性。

关键词：空间机械臂地面遥操作运动控制验证超限检测碰撞检测

Anatomical variation of infra-pyloric artery origination： A prospective multicenter observational study (IPA-Origin)

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Chinese Journal of Cancer Research 2018年第5期30卷 500-507页

作者： Rulin Miao Jianjun Qu Zhengrong Li Daguang Wang Jiang Yu Weidong Zang Yong Li Fenglin Liu Jian Zhang wu Song Kai Ye Su Yan Wei Wang Shuangyi Ren Lu Zang Changqing Jing Li Zhang Kuan Wang Weihua Fu Lin Fan Bin Liang Gang Zhao jun Cai Li Yang Jiaming Zhu jun You Kun Yang Qingxing Huang Zhaojian Niu Ning Ning Xingfeng Qiu Gang Ji Feng Liang Hua Huang Chao Gao Fei Shan Shuangxi Li Yongning Jia Lianhai Zhang Xiangji Ying Yan Zhang Zhaode Bu Xiangqian Su Gang Zhao Ziyu Li Jiafu Ji Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Gastrointestinal Cancer Center Peking University Cancer Hospital & Institute Beijing 100142 China department of Surgical Oncology Weifang People's Hospital Weifang 261000 China department of General Surgery the First Affiliated Hospital of Nanchang University Nanchang 330006 China department of Gastrointestinal Surgery the First Hospital of Jilin University Changehun 130021 China department of General Surgery Nanfang Hospital Southern Medical University Guangzhou 510515 China department of Gastrointestinal Cancer Surgery Fujian Provincial Cancer Hospital Fuzhou 350014 China department of General Surgery Guangdong General Hospital Guangdong Academy of Medical Sciences Guangzhou 510080 China department of General Surgery Zhongshan Hospital Fudan University Shanghai 200032 China department of Gastrointestinal Surgery Hangzhou First People's Hospital Hangzhou 310006 China department of Gastrointestinal Surgery the First Affiliated Hospital Sun Yat-sen University Guangzhou 510080 China department of Surgical Oncology the Second Affiliated Hospital of Fujian Medical University Quanzhou 362000 China department of Surgical Oncology Affiliated Hospital of Qinghai University Xining 810001 China department of Gastrointestinal Surgery Guangdong Provincial Hospital of Chinese Medicine Guangzhou 510120 China department of General Surgery the Second Hospital of Dalian Medical University Dalian 116023 China department of General Surgery Shanghai Ruijin Hospital Shanghai Jiaotong University School of Medicine Shanghai 200025 China department of Gastrointestinal Surgery Shandong Provincial Hospital Affiliated to Shandong University Jinan 250021 China department of Gastrointestinal Surgery Harbin Medical University Cancer Hospital Harbin 150081 China department of General Surgery Tianjin Medical University General Hospital Tianjin 300052 China department of General Surgery the Firs

Objective： Infra-pyloric artery （IPA） is an important anatomical landmark in treatment of gastric cancer and is the key vessel for pylorus-preserving gastrectomy and subgroup of infra-pyloric lymph nodes. However, its anatomical variation is not thoroughly understood. Our study aimed to clarify the origination of the IPA. Methods： We did this prospective, multicenter, open-label, observational study at gastric surgery departments of 34 hospitals in china. Gastric cancer patients aged 18 years or older and scheduled to undergo elective total or distal gastrectomy were assigned. During the surgery, IPA dissecting and exposing the origination point with photographs or video clips were required. The primary outcome was the origination of the IPA. Analysis of variance, χ2 tests and Fisher＇s tests were used to analyze the differences between groups. The study is registered at *** （No. NCT03071237）. Results： Between May 8 and July 31, 2017, 429 patients were assigned for the study, and 419 （97.7%） patients had the IPA dissected and recorded through photograph or video and were included in the primary outcome analysis. The median age was 62 years old, and 73.7% were male. Among the patients, 78.5% received laparoscopic surgery. Single IPA origination was identified in 398 （95.0%） patients, including gastroduodenal artery （GDA） in 154 （36.8%） patients, anterior superior pancreaticoduodenal artery （ASPDA） in 130 （31.0%） patients, and right gastroepiploic artery （RGEA） in 114 （27.2%） patients. Fifteen （3.6%） patients were identified with multiple IPA and 6 （1.4%） patients were identified as IPA absence. The differences in the distribution of surgical approach （P=0.003） and geographic area （P=0.030） were statistically significant. No difference was shown in sex, age, gastrectomy type, tumor location, and clinical T, N and M stage. Conclusions： Our study found that the IPA originates from GDA, ASPDA and RGEA in similar proportions. Laparoscopic surgery may be more

关键词： Infra-pyloric artery origination anatomy gastric cancer

Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology

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Cancer Biology & Medicine 2019年第1期16卷 189-204页

作者： Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong wu Guangdong Lung Cancer Institute Medical Research Center Cancer Center of Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences Affiliated Guangdong Provincial People's Hospital South China University of Technology department of Pathology Peking Union Medical College Hospital Chinese Academy of Medical Sciences National Research Center for Translational Medicine Shanghai Rui Jin Hospital Shanghai Jiao Tong University School of Medicine Lung Tumor Clinical Medical Center Shanghai Chest Hospital Shanghai Jiao Tong University Division of Respiratory Medicine Jinling Hospital Nanjing University School of Medicine department of Oncology Jilin Cancer Hospital department of Pathology National Cancer Center/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College department of Pathology West China Hospital Sichuan University department of Pathology Zhongshan Hospital Fudan University department of Hematology First Affiliated Hospital Institute of Hematology School of Medicine Jinan University Laboratory of Oncology Affiliated Hospital of the Academy of Military Medical Sciences department of Oncology First Clinical College of South China University of Technology/Guangdong Lung Cancer Institute People's Liberation Army Cancer Center of Bayi Hospital Affiliated to nanjing university of Chinese Medicine department of Pathology Sun Yat-sen University Cancer Center department of Pathology Affiliated Hospital of the Academy of Military Medical Sciences department of Pathology Beijing Hospital department of Breast Cancer Pathology and Research Laboratory of Cancer Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center for Cancer Key Laboratory of Cancer Prevention and Therapy Tianjin Tianjin’s Clinical Research Center for Cancer department of Pathology Jinling Hospital Nanjing University School of Medicine State Key Laboratory of Molecular Oncology Department of Medical Oncology National Cancer Center/Canc

Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules ***, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the china Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation.

关键词： Next-generation sequencing technology cancer consensus

Inverted U-Shaped Associations between Glycemic Indices and Serum Uric Acid Levels in the General Chinese Population:Findings from the china Cardiometabolic Disease and Cancer Cohort(4C)Study

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Biomedical and Environmental Sciences 2021年第1期34卷 9-18页

作者： ZHU Yuan Yue ZHENG Rui Zhi WANG Gui Xia CHEN Li SHI Li Xin SU Qing XU Min XU Yu CHEN Yu Hong YU Xue Feng YAN Li WANG Tian Ge ZHAO Zhi Yun QIN Gui jun WAN Qin CHEN Gang GAO Zheng Nan SHEN Fei Xia LUO Zuo Jie QIN Ying Fen HUO Ya Nan LI Qiang YE Zhen ZHANG Yin Fei LIU Chao WANG You Min wu Sheng Li YANG Tao DENG Hua Cong ZHAO Jia jun CHEN Lu Lu MU Yi Ming TANG Xu Lei HU Ru Ying WANG Wei Qing NING Guang LI Mian LU Jie Li BI Yu Fang department of Endocrine and Metabolic Diseases Shanghai Institute of Endocrine and Metabolic DiseasesRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Shanghai National Clinical Research Center for Metabolic Diseases Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR ChinaShanghai National Center for Translational MedicineRuijin Hospital.Shanghai Jiao Tong UniversitySchool of MedicineShanghai 200025China The First Hospital of Jilin university Changchun 130021JinlinChina Qilu Hospital of Shandong university Jinan 250012ShandongChina Affiliated Hospital of Guiyang Medical College Guiyang 550004GuizhouChina Xinhua Hospital Affiliated to Shanghai Jiaotong university school of Medicine Shanghai 200092China Tongji Hospital.Tongji Medical College Huazhong University of Science and TechnologyWuhan 430030HubeiChina sun Yat-sen Memorial Hospital Sun Yat-sen UniversityGuangzhou 510120GuangdongChina The First Affiliated Hospital of Zhengzhou university Zhengzhou 450052HenanChina The Affiliated Hospital of Southwest Medical university Luzhou 646099SichuanChina Fujian Provincial Hospital Fujian Medical UniversityFuzhou 350001FujianChina Dalian Municipal Central Hospital Dalian 116003LiaoningChina The First Affiliated Hospital of Wenzhou Medical university Wenzhou 325000ZhejiangChina The First Affiliated Hospital of Guangxi Medical university Nanning 530021GuangxiChina Jiangxi Provincial People's Hospital Affiliated to Nanchang university Nanchang 330006JiangxiChina The Second Affiliated Hospital of Harbin Medical university Harbin 150086HeilongjiangChina Zhejiang Provincial Center for Disease Control and Prevention Hangzhou 310051ZhejiangChina Central Hospital of Shanghai Jiading District Shanghai 201800China Jiangsu Province Hospital on Integration of Chinese and Western Medicine Nanjing 210028JiangsuChina The First Affiliated Hospital of Anhui Medical university Hefei 230022AnhuiChina Karamay Municipal

Objective The relationship between serum uric acid(SUA)levels and glycemic indices,including plasma glucose(FPG),2-hour postload glucose(2 h-PG),and glycated hemoglobin(HbA1 c),remains *** aimed to explore the associations between glycemic indices and SUA levels in the general Chinese *** The current study was a cross-sectional analysis using the first follow-up survey data from The china Cardiometabolic Disease and Cancer Cohort Study.A total of 105,922 community-dwelling adults aged≥40 years underwent the oral glucose tolerance test and uric acid *** nonlinear relationships between glycemic indices and SUA levels were explored using generalized additive *** A total of 30,941 men and 62,361 women were eligible for the current *** additive models verified the inverted U-shaped association between glycemic indices and SUA levels,but with different inflection points in men and *** thresholds for FPG,2 h-PG,and HbA1 c for men and women were 6.5/8.0 mmol/L,11.0/14.0 mmol/L,and 6.1/6.5,respectively(SUA levels increased with increasing glycemic indices before the inflection points and then eventually decreased with further increases in the glycemic indices).Conclusion An inverted U-shaped association was observed between major glycemic indices and uric acid levels in both sexes,while the inflection points were reached earlier in men than in women.

关键词： Cross-sectional study Serum uric acid Glycemic index Glycemic status

城市区级装配式建筑产业链需求引导政策对比分析

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建筑结构 2022年第13期52卷 1-6页

作者：刘美霞李卫东曹杨贺军孙飞王双军武冰玉梁宝怡住房和城乡建设部科技与产业化发展中心北京100835 北京交通大学经济管理学院北京100044 南京市江宁区住房和城乡建设局南京211100 常州市武进绿色建筑产业集聚示范区管理委员会常州213161 江苏省住房和城乡建设厅南京210036

大力推进装配式建筑发展日益成为建筑业转型创新升级发展的主要载体。城市各区是各级城市组织和实施装配式建筑发展的基本单元。聚焦于我国装配式建筑发展区级第一梯队的南京市江宁区和常州市武进区,对区级层面装配式建筑发展进行系统... 详细信息

大力推进装配式建筑发展日益成为建筑业转型创新升级发展的主要载体。城市各区是各级城市组织和实施装配式建筑发展的基本单元。聚焦于我国装配式建筑发展区级第一梯队的南京市江宁区和常州市武进区,对区级层面装配式建筑发展进行系统化的案例对比分析,探究装配式建筑需求引导政策在区级层面的激励效果及装配式建筑项目和产业发展之间的互动关系。并结合系统动力学佐证了相关政策对两区装配式建筑占比提高以及相关部品部件产业链产值增加的重要促进作用。两区有代表性的装配式建筑需求引导政策(主要包括引导产业链构建、协同推进机制、质量追溯机制、“一核引领、全区联动”创新模式以及打造专业人才队伍),为其他区县级层面主管部门发展装配式建筑提供了宝贵的经验借鉴。

关键词：装配式建筑需求引导政策产业发展地区经验

A practical community-based response strategy to interrupt Ebola transmission in sierra Leone, 2014–2015

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Infectious Diseases of Poverty 2016年第1期5卷 670-679页

作者： Zhong-Jie Li Wen-Xiao Tu Xiao-Chun Wang Guo-Qing Shi Zun-Dong Yin Hai-jun Su Tao Shen Da-Peng Zhang Jian-Dong Li Shan Lv Chun-Li Cao Rui-Qian Xie Hong-Zhou Lu Rong-Meng Jiang Zheng Cao Zhi-Jie An Lei-Lei Li Jie Xu Yan-Wen Xiong Wei Zang Wei Zhang Hong-Wei Zhang Wen-Sen Chen Hua Ling Wen Xu Jian Cai Huan-Jin Luo Xue-Sheng Xing Can-jun Zheng Qiang Wei Xin-Xu Li Mei Li Hai Jiang Li-Quan Deng Ming-Quan Chen Xiang Huo Feng Xu Xue-Hui Lai Xi-Chen Bai Long-Jie Ye Jian-Yi Yao Wen-wu Yin Jiao-Jin sun Lin Xiao Fu-Qiang Liu Xiao-Qiang Liu Hong-Wei Fan Zeng-Qiang Kou Ji-Kun Zhou Hao Zhang Da-Xin Ni Thomas TSamba Qun Li Hong-Jie Yu Yu Wang Xiao-Feng Liang Division of Infectious Disease Key Laboratory of Surveillance and Early-warning on Infectious DiseaseChinese Center for Disease Control and PreventionBeijingChina Public Health Emergency Center Chinese Center for Disease Control and PreventionBeijingChina National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Chinese Field Epidemiology Training Program Chinese Center for Disease Control and PreventionBeijingChina National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina Bureau of Disease Prevention and Control National Health and Family Planning Commission of the People’s Republic of ChinaBeijingChina National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina National Institute of Parasitic Disease Chinese Center for Disease Control and PreventionShanghaiChina Chinese Center for Health Education BeijingChina department of Infectious Diseases Shanghai Public Health Clinical CenterShanghaiChina Beijing Ditan Hospital Capital Medical UniversityBeijingChina Health News BeijingChina National Institute for Communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina department of Training Chinese Center for Health EducationBeijingChina Center for Infectious Diseases Beijing Youan HospitalCapital Medical UniversityBeijingChina Infection Management The First Affiliated Hospital of Nanjing Medical UniversityNanjingChina Chongqing Municipal Center for Disease Control and Prevention ChongqingChina Yunnan Provincial Center for Disease Control and Prevention KunmingChina Division of Infectious Disease Control and Prevention Zhejiang Provincial Center for Disease Control and PreventionHangzhouChina Guangdong Provincial Center for Disease Control and Prevention GuangzhouChina Division of Acute Infectious Disease Control and Prevention Hubei Provincial Center for Disease Control and PreventionW

Background:The Ebola virus disease spread rapidly in West Africa in 2014,leading to the loss of thousands of *** engagement was one of the key strategies to interrupt Ebola transmission,and practical community level measures needed to be explored in the field and tailored to the specific context of ***:First,community-level education on Ebola virus disease(EVD)prevention was launched for the community’s social mobilizers in six districts in Sierra Leone beginning in November ***,from January to May of 2015,in three pilot communities,local trained community members were organized to engage in implementation of EVD prevention and transmission interruption measures,by involving them in alert case report,contact tracing,and social *** epidemiological indicators of transmission interruption in three study communities were ***:A total of 6016 community social mobilizers from 185 wards were trained by holding 279 workshops in the six districts,and EVD message reached an estimated 631680 *** three pilot communities,72 EVD alert cases were reported,with 70.8%of them detected by trained local community members,and 14 EVD cases were finally *** tracing detected 64.3%of EVD *** median duration of community infectivity for the cases was 1 *** secondary attack rate was 4.2%,and no third generation of infection was *** health worker was infected,and no unsafe burial and noncompliance to EVD control measures were *** community-based measures were modeled to reduce 77 EVD cases,and the EVD-free goal was achieved four months earlier in study communities than whole country of Sierra ***: The community-based strategy of social mobilization and community engagement was effective in casedetection and reducing the extent of Ebola transmission in a country with weak health system. The successfullypractical experience to reduce the risk of Ebola transmission in the

关键词： Ebola virus disease Community engagement Health education Outbreak control

Diagnosis and Treatment of Acne Inversa/Hidradenitis Suppurativa in china: An Expert Consensus Statement (2021 Version)

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International Journal of Dermatology and Venereology 2021年第2期4卷 100-108页

作者： Hong Fang Xing-Hua Gao Song-Mei Geng Heng Gu jun Gu Li He Xian Jiang Hong-Zhong Jin Qiang Ju Xiao-Jing Kang Wei Lai Cheng-Xin Li Hang Li Heng-Jin Li Shan-Shan Li Yu-Zhen Li Qing sun Juan Tao Baoxi Wang Gang Wang Xin-Feng wu Lei-Hong Xiang Hong-Fu Xie Hao-Xiang Xu Jin-Hua Xu Yan Yan Zhi-Zhong Zheng department of Dermatology The First Affiliated Hospital of Zhejiang UniversityHangzhouZhejiang 310003China department of Dermatology No.1 Hospital of China Medical UniversityShenyangLiaoning 110001China department of Dermatology The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi 710061China Hospital for Skin Diseases(Institute of Dermatology) Chinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210042China department of Dermatology Shanghai Tenth People’s HospitalTongji University School of MedicineShanghai 200072China department of Dermatology First Affiliated Hospital of Kunming Medical UniversityKunmingYunnan 650032China department of Dermatology West China HospitalSichuan UniversityChengduSichuan 610041China department of Dermatology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China department of Dermatology Renji HospitalSchool of MedicineShanghai Jiaotong UniversityShanghai 200025China department of Dermatology People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqiXinjiang 830001China department of Dermatology and Venereology The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510630China department of Dermatology First Medical Center of Chinese PLA General HospitalBeijing 100853China department of Dermatology and Venerology Peking University First HospitalBeijing 100034China department of Dermatology Hainan Hospital of PLA General HospitalSanyaHainan 572013China department of Dermatology and Venereology The First Hospital of Jilin UniversityChangchunJilin 130021China department of Dermatology Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiang 150086China department of Dermatology Qilu Hospital of Shandong UniversityJinanShandong 250012China department of Dermatology Affiliated Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China De

Acne inversa/hidradenitis suppurativa is a chronic,recurrent,inflammatory skin disease that affects the pilosebaceous units,causinfollicular *** etiology and pathogenesis of acne inversa/hidradenitis suppurativa involves internal and external factors such as genetic susceptibility,inflammation and immunity,microorganisms,obesity,and *** inversa/hidradenitis suppurativa is difficult to treat,and the current aim of treatment is to control the frequency and duration of disease flares and improve the quality of *** protocols for acne inversa/hidradenitis suppurativa should be selected based on the disease severity *** treatments include antibiotics,retinoids,biologics,immunosuppressive agents,and antiandrogen *** treatments include surgery and laser/light *** consensus aims to further standardize the diagnosis and treatment procedures of acne inversa/hidradenitis suppurativa in china to facilitate its diagnosis and treatment.

关键词： acne inversa consensus diagnosis hidradenitis suppurativa therapy

胃非特殊类型外周T细胞性淋巴瘤伴CD20和CD79α异常表达1例

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中华病理学杂志 2022年第7期51卷 667-669页

作者：彭双双吴鸿雁杨军孙庆洋周照雅史倩芸何璐陈洁宇樊祥山南京大学医学院附属鼓楼医院病理科南京210008 南京江北医院病理科南京210044 南京医科大学鼓楼临床医学院病理科南京210008

伴CD20和CD79α异常表达的非特殊类型外周T细胞淋巴瘤(PTCL)极为罕见,本文报道1例发生于胃部的病例。虽然T细胞标志物和B细胞标志物同时阳性,但T细胞受体克隆性基因重排阳性明确了诊断。本文分析了该PTCL呈CD20和CD79α阳性表达的可能原... 详细信息

伴CD20和CD79α异常表达的非特殊类型外周T细胞淋巴瘤(PTCL)极为罕见,本文报道1例发生于胃部的病例。虽然T细胞标志物和B细胞标志物同时阳性,但T细胞受体克隆性基因重排阳性明确了诊断。本文分析了该PTCL呈CD20和CD79α阳性表达的可能原因,且包含CD20单克隆抗体利妥昔单抗在内的R-CDOP(利妥昔单抗,环磷酰胺,脂质体多柔比星,长春地辛,醋酸泼尼松)治疗方案对患者具有一定疗效,为深入了解此种病例的临床病理学特征、治疗及预后提供参考依据。

关键词：利妥昔单抗异常表达克隆性基因重排 CD7 长春地辛临床病理学特征治疗及预后醋酸泼尼松

A 14-year multi-institutional collaborative study of Chinese pelvic floor surgical procedures related to pelvic organ prolapse

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Chinese Medical Journal 2021年第2期134卷 200-205页

作者： Zhi-Jing sun Xiu-Qi Wang Jing-He Lang Tao Xu Yong-Xian Lu Ke-Qin Hua Jin-Song Han Huai-Fang Li Xiao-Wen Tong Ping Wang Jian-Liu Wang Xin Yang Xiang-Hua Huang Pei-Shu Liu Yan-Feng Song Hang-Mei Jin Jing-Yan Xie Lu-Wen Wang Qing-Kai wu Jian Gong Yan Wang Li-Qun Wang Zhao-Ai Li Hui-Cheng Xu Zhi-jun Xia Li-Na Gu Qing Liu Lan Zhu department of Obstetrics and Gynecology Peking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100730China department of Obstetrics and Gynecology Graduate School of Peking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100730China department of Epidemiology and Biostatistics Institute of Basic Medical SciencesChinese Academy of Medical Sciences and School of Basic MedicinePeking Union Medical CollegeBeijing 100730China department of Obstetrics and Gynecology The Fourth Medical CenterChinese PLA General HospitalBeijing 100048China department of Gynecology Obstetrics and Gynecology Hospital of Fudan UniversityShanghai 200433China department of Obstetrics and Gynecology Peking University Third HospitalBeijing 100083China department of Obstetrics and Gynecology Tongji HospitalTongji UniversityShanghai 200065China department of Obstetrics and Gynecology West China Second HospitalSichuan UniversityKey Laboratory of Birth Defects and Related Diseases of Women and ChildrenMinistry of EducationChengduSichuan 061110China department of Obstetrics and Gynecology Peking University People’s HospitalBeijing 100044China department of Obstetrics and Gynecology The Second Hospital of Hebei Medical UniversityShijiazhuangHebei 075100China department of Obstetrics and Gynecology Qilu Hospital of Shandong UniversityJinanShandong 250002China department of Obstetrics and Gynecology 900 Hospital of the Joint Logistics TeamFuzhouFujian 350025China department of Obstetrics and Gynecology Women’s HospitalSchool of MedicineZhejiang UniversityHangzhouZhejiang 310000China department of Obstetrics and Gynecology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu 210006China department of Obstetrics and Gynecology The Third Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450000China department of Obstetrics and Gynecology Shanghai Jiao Tong University Sixth HospitalShanghai 200300China department of Gyn

Background:It has been a global trend that increasing complications related to pelvic floor surgeries have been reported over *** current study aimed to outline the development of Chinese pelvic floor surgeries related to pelvic organ prolapse(POP)over the past 14 years and investigate the potential influence of enhanced monitoring conducted by the Chinese Association of Urogynecology since ***:A total of 44,594 women with POP who underwent pelvic floor surgeries between October 1,2004 and September 30,2018 were included from 22 tertiary academic medical *** data were reported voluntarily and obtained from a *** compared the proportion of each procedure in the 7 years before and 7 years after September 30,*** data were analyzed by performing Z test(one-sided).Results:The number of different procedures during October 1,2011-September 30,2018 was more than twice that during October 1,2004-September 30,*** pelvic floor surgeries related to POP,the rate of synthetic mesh procedures increased from 38.1%(5298/13,906)during October 1,2004-September 30,2011 to 46.0%(14,107/30,688)during October 1,2011-September 30,2018,whereas the rate of non-mesh procedures decreased from 61.9%(8608/13,906)to 54.0%(16,581/30,688)(Z=15.53,P<0.001).Regarding synthetic mesh surgeries related to POP,the rates of transvaginal placement of surgical mesh(TVM)procedures decreased from 94.1%(4983/5298)to 82.2%(11,603/14,107)(Z=20.79,P<0.001),but the rate of laparoscopic sacrocolpopexy(LSC)procedures increased from 5.9%(315/5298)to 17.8%(2504/14,107).Conclusions:The rate of synthetic mesh procedures increased while that of non-mesh procedures decreased *** rate of TVM procedures decreased while the rate of LSC procedures increased *** registration number:NCT03620565,https://***.

关键词： Laparoscopic sacrocolpopexy Pelvic organ prolapse Synthetic mesh Transvaginal placement of surgical mesh