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Coinfection of SARS-CoV-2 Omicron variant and other respiratory pathogens in children

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World Journal of Pediatrics 2024年第1期20卷 92-96页

作者： Wei Li Bing-Han wang Bao-Hai chen Yi sun Lin Li Wen-Qing Xiang Ahmed Faisal Ali Lin-Xuan Su Hai-Yan Mao Hong-Qiang Shen Qiang Shu Department of Clinical Laboratory Children's HospitalNational Clinical Research Center for Child HealthZhejiang University School of MedicineHangzhouChina School of Public Health Zhejiang University School of MedicineHangzhouChina Department of information Center Children's HospitalZhejiang University School of MedicineHangzhouChina zhejiang Provincial Center for Disease Control and Prevention HangzhouChina Department of Thoracic&Cardiovascular Surgery Children's HospitalNational Clinical Research Center for Child HealthZhejiang University School of MedicineHangzhouChina

Since the outbreak of coronavirus disease 2019(COVID-19),the entire world has been affected by the epidemic[1,2].On November 9,2021,a variant of the novel coronavirus B.1.1.529 was detected for the first time from case samples in South *** Omicron strain spread and mutated significantly *** variant has the characteristics of escape immunity,which can induce relatively extreme disease and reduce the neutralization of antibodies in vaccinators,and is more likely to be reinfected[3,4].The clinical presentation of severe acute respiratory syndrome coronavirus 2(SARSCoV-2)in children has mild symptoms and a lower risk of hospitalization and death.

关键词： respiratory immunity acute

Global Adaptive Control of A Class of Uncertain Nonlinear Systems Using Neural Networks

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Global Adaptive Control of A Class of Uncertain Nonlinear Sy...

第二十七届中国控制会议

作者： chen pengnian1,Qin Huashu2,sun mingxuan3 1.Department of Mathematics,china Institute of Metrology,hangzhou 310018,P.R.china 2.Institute of Systems Science,The Chinese Academy of Sciences,Beijing 100080,P.R.china 3.college of information engineering,zhejiang Univewrsity of technology,hangzhou 310014,P.R.china

The paper considers the problem of global adaptive tracking for a class of uncertain nonlinear systems in which the uncertainty is impossible to be *** the help of the technique of unit partition in differential topology,a result on global approximation of function using neural networks is *** the result,a method of global adaptive neural network control for the uncertain nonlinear system is *** method ensures that the tracking error converges to an arbitrarily given small neighborhood of *** the tracked signal is constant,the tracking error converges to zero.

关键词： Nonlinear system Adaptive control Neural network

Boosting oxygen reduction in acidic media through integration of Pt-Co alloy effect and strong interaction with carbon defects

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Nano Research 2024年第9期17卷 7900-7908页

作者： Nannan Ji Haoyun Sheng Shilong Liu Yangyuan Zhang Hongfei sun Lingzhi Wei Ziqi Tian Peng Jiang Qianwang chen Jianwei Su Institutes of Physical Science and information technology Key Laboratory of Structure and Functional Regulation of Hybrid MaterialsAnhui UniversityHefei 230601China Ningbo Institute of Materials technology and engineering Chinese Academy of SciencesNingbo 315201China Hefei National Laboratory for Physical Science at Microscale Department of Materials Science&EngineeringUniversity of Science and Technology of ChinaHefei 230026China International Collaborative Laboratory of 2D Materials for Optoelectronics Science and technology of Ministry of Education Institute of Microscale OptoelectronicsShenzhen UniversityShenzhen 518060China

Optimization of Pt atom utilization efficiency is critical for the development of proton-exchange-membrane fuel *** we aim to develop an efficient oxygen reduction reaction(ORR)catalyst with a low Pt content through the concurrent modification of Pt-Co alloy catalysts and carbon *** the present study,ultrafine Pt-Co alloy nanoparticles are successfully synthesized and stabilized by topological carbon defects via adopting the ammonia thermal *** the low Pt loading,the obtained catalyst exhibits an impressive half-wave potential of 0.926 V versus the reversible hydrogen electrode in 0.1 M HClO_(4)***,the durability testing using the timed-current method demonstrates a tiny loss of only 3.6%after 12 *** experimental results and theoretical calculations demonstrate that topological carbon defects significantly enhance the charge transfer processes at the alloy/carbon interface,contributing to the strong electronic metal-support interactions between the Pt-Co alloy nanoparticles and topological carbon *** interactions,along with the alloy effect,play a crucial role in promoting the ORR performance in acidic media.

关键词： electrocatalysis oxygen reduction reaction Pt-Co alloy electronic interaction topological carbon defects

Multidisciplinary and multiscale nanoscience research roadmap based on large scientific facilities

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Science china Chemistry 2024年第8期67卷 2497-2523页

作者： Yuan Zeng Shuhan Zhang Yuecong Guo Yalin Cong Xu Ding Peihua Li Yunxiang Lin Wenzhi Ren Hui Su Weigang sun Liuxin Xu Guikai Zhang Shihua chen Yu chen Weiren cheng Shengqi Chu Yong Guan Jinru Han Jie Lin Hengjie Liu Zheyi Liu Pan Luo Fanchun Meng Sicong Qiao Zongyin Song Ying wang Zhao Wu chenyu Yang Meng Yang Shirui Yang Zi Yin Zhibin Yin Pengjun Zhang Hongyu Zhang Pingping Zheng Jia Zhou Wanlin Zhou Pengfei An He cheng Chunhai Fan Xingjiu Huang Yong Lei Lina Li Mu Li Qinghua Liu Shuming Peng Li Song Zhihu sun Yangchao Tian Fangjun wang Lihua wang Liming wang Shiqiang Wei Aiguo Wu Chunlei Xiao Xueming Yang Panchao Yin Jing Zhang Mingxin Zhang Yaling wang Chunying chen CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety New Cornerstone Science LaboratoryNational Center for Nanoscience and TechnologyBeijing 100190China university of Chinese Academy of Sciences Beijing 100049China National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029China Institute of Solid State Physics Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China Institutes of Physical Science and information technology Anhui UniversityHefei 230601China Ningbo Key Laboratory of Biomedical Imaging Probe Materials and technology Zhejiang International Cooperation Base of Biomedical Materials Technology and ApplicationCAS Key Laboratory of Magnetic Materials and DevicesNingbo Cixi Institute of Biomedical EngineeringZhejiang Engineering Research Center for Biomedical MaterialsNingbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201China Advanced Energy Science and technology Guangdong Laboratory Huizhou 516000China college of Chemistry and Chemical engineering Hunan Normal UniversityChangsha 410081China State Key Laboratory of Luminescent Materials and Devices South China Advanced Institute for Soft Matter Science and TechnologySouth China University of TechnologyGuangzhou 510640China Beijing Synchrotron Radiation Facility Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China CAS Key Laboratory of Separation Sciences for Analytical Chemistry Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China State Key Laboratory of Molecular Reaction Dynamics Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China Institute of Advanced Science Facilities Shenzhen 518107China State Key Laboratory of Coal Conversion Institute of Coal ChemistryChinese Academy of SciencesTaiyuan 030001China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Acade

With the advancement of modern science and technology, large scientific facilities are increasingly oriented toward demand and application, and can be used for basic research as well as serving multiple disciplines. Developing large scientific facilities and related analytical technologies enhances understanding of large scientific facilities and popularizes their application in research across multiple disciplines. The combination of light or neutron sources from large scientific facilities and advanced analytical technologies can be achieved for materials structure information, dynamics study of chemical reactions, high dissociation of biomolecules, 3D visualization of energy materials or biological samples, etc. We first introduce the progress of domestic large scientific facilities of synchrotron radiation(SR) and free electron lasers(FELs) with different wavelengths and neutron *** further discuss the comparison between Chinese and typical foreign facilities in X-ray radiation from X-ray tubes, synchrotrons, X-ray FELs, and neutron sources based on physical parameters of light and neutron sources. In addition, we focus on the technological progress and perspectives combined with advanced X-ray radiation and neutron sources of large scientific facilities in china, especially in the nanoscience fields of energy catalysis and biological science. We hope that this roadmap will provide references on technology and methods to experimental users, as well as prospects for future development of technologies based on large research infrastructure facilities. Comprehensive studies and guidelines for basic research to practical application in various disciplines can be made with the assistance of large scientific facilities.

关键词： large scientific facilities synchrotron radiation FEL light sources neutron sources spectroscopic analysis methods X-ray imaging techniques structural information chemical dynamics

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First wetland mapping at 10-m spatial resolution in South America using multi-source and multi-feature remote sensing data

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Science china Earth Sciences 2024年第10期67卷 3252-3269页

作者： Weiwei sun Gang YANG Yuling HUANG Dehua MAO Ke HUANG Lin ZHU Xiangchao MENG Tian FENG Chao chen Yong GE Department of Geography and Spatial information Techniques Ningbo University State Key Laboratory of Resources and Environmental information System Institute of Geographic Sciences & Natural Resources ResearchChinese Academy of Sciences Natural Resources and Planning Bureau Shanghai Pudong New District Key Laboratory of Wetland Ecology and Environment Northeast Institute of Geography and Agroecology Chinese Academy of Sciences Faculty of Electrical engineering and Computer Science Ningbo University School of Geography Science and Geomatics engineering Suzhou University of Science and Technology

Wetland degradation has been accelerating in recent years globally. Accurate information on the geographic distribution and categories of wetlands is essential for their conservation and management. Despite being the world′s fourth largest continent, South America has limited research on wetland mapping, and there is currently no available map that provides comprehensive information on wetland distribution and categories in the region. To address this issue, we used Sentinel-1, Sentinel-2 and SRTM data, developed a sample collection method and a wetland mapping method with a collection of multi-source features such as optical features, polarization features and shape features for South American wetlands. We produced a 10-m resolution wetland map based on the Google Earth Engine（GEE） platform. Our Level-1 wetland cover map accurately captured six wetland sub-categories with an overall accuracy of 96.24% and a kappa coefficient of 0.8649, while our Level-2 water cover map included five sub-categories with an overall accuracy of 97.23% and a kappa coefficient of0.9368. The results show that the total area of existing wetlands in South America is approximately 1,737,000 km2, which is6.8% of the total land area. Among the ten wetland categories, shallow sea had the largest area（960,527.4 km2）, while aquaculture ponds had the smallest area 1513.6 km2. Swamp had the second largest area（306,240.1 km2）. Brazil, Argentina,Venezuela, Bolivia, and Colombia were found to have the largest wetland areas, with Brazil and Colombia having the most diverse wetland categories. This product can serve as baseline data for subsequent monitoring, management, and conservation of South American wetlands.

关键词： Wetland mapping Google Earth Engine Sentinel imagery South America

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Two-dimensional materials for future information technology: status and prospects

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Science china(information Sciences) 2024年第6期67卷 1-147页

作者： Hao QIU Zhihao YU Tiange ZHAO Qi ZHANG Mingsheng XU Peifeng LI Taotao LI Wenzhong BAO Yang CHAI Shula chen Yiqi chen Hui-Ming chenG Daoxin DAI Zengfeng DI Zhuo DONG Xidong DUAN Yuhan FENG Yu FU Jingshu GUO Pengwen GUO Yue HAO Jun HE Xiao HE Jingyi HU Weida HU Zehua HU Xinyue HUANG Ziyang HUANG Ali IMRAN Ziqiang KONG Jia LI Qian LI Weisheng LI Lei LIAO Bilu LIU Can LIU Chunsen LIU Guanyu LIU Kaihui LIU Liwei LIU Sheng LIU Yuan LIU Donglin LU Likuan MA Feng MIAO Zhenhua NI Jing NING Anlian PAN Tian-Ling REN Haowen SHU Litao sun Yue sun Quanyang TAO Zi-Ao TIAN Dong wang Hao wang Haomin wang Jialong wang Junyong wang Wenhui wang Xingjun wang Yeliang wang Yuwei wang Zhenyu wang Yao WE... School of Electronic Science and engineering Nanjing University School of Integrated Circuits Interdisciplinary Research Center for Future Intelligent Chips (Chip-X)Nanjing University School of Integrated Circuit Science and engineering Nanjing University of Posts and Telecommunications State Key Laboratory of Infrared Physics Shanghai Institute of Technical Physics Chinese Academy of Sciences School of Physics and Key Lab of Quantum Materials and Devices of the Ministry of Education School of Electronic Science & EngineeringSoutheast University college of Integrated Circuits State Key Laboratory of Silicon and Advanced Semiconductor MaterialsZhejiang University Suzhou Laboratory State Key Laboratory of Integrated Chips and Systems School of MicroelectronicsFudan University Shaoxin Laboratory Department of Applied Physics The Hong Kong Polytechnic University Key Laboratory for Micro-Nano Physics and technology of Hunan Province College of Materials Science and EngineeringHunan University college of Integrated Circuits Zhejiang University Shenzhen Geim Graphene Center Shenzhen Key Laboratory of Layered Materials for Value-Added ApplicationsTsinghua-Berkeley Shenzhen Institute & Institute of Materials ResearchTsinghua Shenzhen International Graduate SchoolTsinghua University State Key Laboratory of Extreme Photonics and Instrumentation College of Optical Science and EngineeringInternational Research Center for Advanced PhotonicsZijingang CampusZhejiang University National Key Laboratory of Materials for Integrated Circuits Shanghai Institute of Microsystem and Information TechnologyChinese Academy of Sciences CAS Key Laboratory of Nanophotonic Materials and Devices & Key Laboratory of Nanodevices and Applications i-LabSuzhou Institute of Nano-Tech and Nano-Bionics (SINANO)Chinese Academy of Sciences college of Chemistry and Chemical engineering Hunan University Key Laboratory of Quantum State Construction and Manipulation (Ministry of Education) Department of PhysicsRenmin University of China School

Over the past 70 years, the semiconductor industry has undergone transformative changes,largely driven by the miniaturization of devices and the integration of innovative structures and materials. Two-dimensional(2D) materials like transition metal dichalcogenides(TMDs) and graphene are pivotal in overcoming the limitations of silicon-based technologies, offering innovative approaches in transistor design and functionality, enabling atomic-thin channel transistors and monolithic 3D integration. We review the important progress in the application of 2D materials in future information technology, focusing in particular on microelectronics and optoelectronics. We comprehensively summarize the key advancements across material production, characterization metrology, electronic devices, optoelectronic devices, and heterogeneous integration on silicon. A strategic roadmap and key challenges for the transition of 2D materials from basic research to industrial development are outlined. To facilitate such a transition, key technologies and tools dedicated to 2D materials must be developed to meet industrial standards, and the employment of AI in material growth, characterizations, and circuit design will be essential. It is time for academia to actively engage with industry to drive the next 10 years of 2D material research.

关键词： two-dimensional (2D) materials information technology production technology standardization of characterization microelectronicdevices optoelectronic devices multi-functional integration

Non-destructive measurement of pear internal quality indices by visible and near-infrared spectrometric techniques

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Non-destructive measurement of pear internal quality indices...

The First International Conference on Computers and Computing Technologies in Agriculture

作者： LIU YAN-DE~(1,2,*) chen XING-MIAO~1 sun XU-DONG~1 YING YI-BIN~2 1 college of engineering Jiangxi Agricultural university Nanchang 330045,china 2 college of Biosystems and Food Science zhejiang university Hangzhuo 310029,china

The feasibility of non-destructive measurement of intemal quality indices of intact pear fruit using visible and near-infrared(Vis/NIR) spectrometric techniques was *** the wavelength region from 350 to 1800 nm,calibration models relating Vis/NIR spectra to soluble solids content (SSC) and firmness were developed based on multilinear regression(MLR),principal component regression (PCR) and partial least squares regression (PLSR) with respect to the logarithms of the reflectance reciprocal log(1/R),its first derivative D log (1/R) and its second derivative D log(1/R).The best combination,based on the reliable and robust models obtained,was the PLS models with respect to log (1/R) at an equatorial position of the *** with the PLS model with respect to log(1/R) resulted in correlation coefficients(r) of 0.9121 and 0.8541, and root mean standard error of prediction(RMSEP) of 0.6619 and 1.2324 for SSC and firmness, *** experimental results indicate that the Vis/NIR spectrometric technique could provide an accurate,reliable and non-destructive method for assessing internal quality indices of pear fruit, especially for SSC.

关键词： firmness multivariate calibration technique non-destructive measurement pear fruit soluble solids content visible and near-infrared spectrometric techniques

Controlling the Microbial Contamination of RTE Foods during Processing and Selling Using the Principle of HACCP in Big Supermarket of Nanjing,china

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Controlling the Microbial Contamination of RTE Foods during ...

2012年环境污染与大众健康学术会议

作者： Shi Ruofu 1,2 , wang Shaokang 1 , chen Guowei 1 , sun Guiju 1 (responding author) 1 Key Laboratory of Environmental Medicine and engineering of Ministry of Education, and Department of Nutrition and Food Hygiene, School of Public Health, Medical college, Southeast university Nanjing, P.R.china 2 Environment and Bioengineering Institute Nanjing university of Science and technology Nanjing, P.R.china

Hazard Analysis and Critical Control Point （HACCP） is a systematic intervention management on food safety. Under its principles we established a simple and flexible quality control measure to direct hygiene of ready-to-eat （RTE） foods during processing and selling. 8 kinds of RTE meat products, including Stewed Duck Gizzard, Saline Chicken Claws, Soy Sauced Chicken Wings, Spiced Beef, Sweet and Sour Spareribs, Meatball, Melopsittacus Packages of Meat, Braised Trotter in Red Sauce were collected from four large-scale supermarkets located in Nanjing, china. Knives, chopping boards, trays, shovels, air, water and cotton swab of hands of sales staff were sampled to analysis the total number of colonies, coliform, salmonella, Shigella, and Staphylococcus Aureus. In two supermarket measures for controlling microbial contamination in these 8 kinds of RTE meat products were carried out according to the HACCP principles. The critical control points （CCPs） includes material selection, containers hygiene, the amount of cooked meat in the one pot, the heating temperature, cooked food sales time and storage temperature, health habits of the sales staff. The following measures were adopted for controlling microbial contamination:the health education to the employees on food safety knowledge, the establishment and implementation of standard operation procedure （SOP） for the cleaning and disinfection, enactment of the CCPs critical limits and control measures. Another two supermarkets were as the control. After one month the samples of above 8 kinds of RTE meat products were collected again for the microbial determination. According to the Chinese national standard GB2726-2005 （Hygienic standard for cooked meat products）, the results showed the passing rates of RTE meat products before and after intervention in intervention supermarkets were 70.8% and 96.9% respectively, and there was significantly difference （p＜0.05）. However in the two control supermarkets, the passing rates of R

关键词： Microbial contamination control measure evaluation RTE foods processing and selling Funded by Jiang Su Province Soft Science Program (BR2004512 and BR2006020)

Analysis for Possible Source(s) of Bacteria Contamination of Ready-to-Eat Meat Products in Processing and Selling in Big Supermarket of Nanjing,china

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Analysis for Possible Source(s) of Bacteria Contamination of...

2012年环境污染与大众健康学术会议

作者： Shi Ruofu 1,2 , sun Guiju 1 (responding author), wang Shaokang 1 , Huang zongjun 2 , chen Guowei 1 1 Key Laboratory of Environmental Medicine and engineering of Ministry of Education, and Department of Nutrition and Food Hygiene, School of Public Health, Medical college, Southeast university Nanjing, P.R.china 2 Environment and Bioengineering Institute Nanjing university of Science and technology Nanjing, P.R.china

8 kinds of ready-to-eat (RTE) meat products, including Stewed Duck Gizzard, Saline Chicken Claws, Soy Sauced Chicken Wings, Spiced Beef, Sweet and Sour Spareribs, Meatball, Melopsittacus Packages of Meat, Braised Trotter in Red Sauce were collected from four large-scale supermarkets located in Nanjing, china. To analysis possible sources of bacteria contamination of RTE food during the processing and subsequent selling,knives, chopping boards, trays, shovels, air, water and cotton swab of hands of sales staff were sampled, the total number of colonies, coliform, salmonella, Shigella, and Staphylococcus Aureus count were determined. The results showed that these RTE foods were contaminated by bacteria at different levels, overall passing rate was 68.8%, the over-limit ratio of the total number of colonies was 17.5%, the over-limit ratio of coliform took up 18.8% according to the Chinese national standard GB2726-2005 (Hygienic standard for cooked meat products). With regard to pathogen, the detection ratios of salmonella and Staphylococcus Aureus were 4.2% and 2.1% respectively. The results also showed that the bacteria contamination of cooked food was caused by the falling bacteria in the air in the producing and selling space, the clamps, chopping boards, knives, container of food and the hands of the operators. The total number of colonies in meat products positively correlated with the amount of cooked meat in the one pot (r=0.87728, P=0.0217), and negatively correlated with the maximum temperature in the center of the meat (r =-0.81633, P =0.0475). During the sales process of RTE foods, the passing rate was decreasing with the time, which the passing rate was just 60.6% at 4h. Our results suggest that the hygiene condition of selling in supermarket needed to be improved. The problem is to strengthen food safety education to employees and enhance their hygiene consciousness. Meanwhile the government should formulate the homemade cooked meat hygiene regulations and

关键词： Sources of contamination RTE meat products Processing and selling Supermarket Funded by Jiang Su Province Soft Science Program (BR2004512 and BR2006020)