检索结果-南通市图书馆

Unraveling brain aging through the lens of oral microbiota

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第7期20卷 1930-1943页

作者： Qinchao Hu Si Wang Weiqi Zhang jing Qu Guang-Hui Liu State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Hospital of Stomatology Guanghua School of StomatologyGuangdong Provincial Key Laboratory of StomatologySun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Advanced Innovation Center for Human Brain Protection and National Clinical Research Center for Geriatric Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Aging Translational Medicine Center International Center for Aging and CancerBeijing Municipal Geriatric Medical Research CenterXuanwu HospitalCapital Medical UniversityBeijingChina CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of Sciences and China National Center for BioinformationBeijingChina University of Chinese Academy of Sciences BeijingChina Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijingChina Aging Biomarker Consortium BeijingChina State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijingChina Beijing Institute for Stem Cell and Regenerative Medicine BeijingChina

The oral cavity is a complex physiological community encompassing a wide range of *** of oral microbiota can lead to various oral infectious diseases,such as periodontitis and tooth decay,and even affect systemic health,including brain aging and neurodegenerative *** studies have highlighted how oral microbes might be involved in brain aging and neurodegeneration,indicating potential avenues for intervention *** this review,we summarize clinical evidence demonstrating a link between oral microbes/oral infectious diseases and brain aging/neurodegenerative diseases,and dissect potential mechanisms by which oral microbes contribute to brain aging and *** also highlight advances in therapeutic development grounded in the realm of oral microbes,with the goal of advancing brain health and promoting healthy aging.

关键词： Alzheimer's disease brain aging multiple sclerosis neurodegeneration neurodegenerative diseases oral microbiota Parkinson's disease periodontitis bacteria Porphyromonas gingivalis

在线全文

学校读者我要写书评

暂无评论

固载脂肪酶催化制备生物柴油

内蒙古民族大学学报（自然科学版） 2013年第5期28卷 522-524页

作者：孙景繁徐玲包呼和牧区乐美春赵朝军通辽市产品质量计量检测所内蒙古通辽028000 内蒙古民族大学化学化工学院内蒙古通辽028043

本实验探讨了固载脂肪酶催化蓖麻油和甲醇酯交换反应制备生物柴油,研究了醇油摩尔比、反应时间与温度等因素对酯化反应的影响.通过固载脂肪酶,很大程度上增强了其稳定性和抗酸碱性,提高了酶的重复使用率,节约成本.结果表明:固载脂肪酶... 详细信息

本实验探讨了固载脂肪酶催化蓖麻油和甲醇酯交换反应制备生物柴油,研究了醇油摩尔比、反应时间与温度等因素对酯化反应的影响.通过固载脂肪酶,很大程度上增强了其稳定性和抗酸碱性,提高了酶的重复使用率,节约成本.结果表明:固载脂肪酶催化酯交换反应最佳反应条件为醇油物质的量比为6∶1,固载酶2%(油重),反应时间为2 h,反应温度为50℃,蓖麻油的转化率最高为92.44%.

关键词：固载脂肪酶蓖麻油生物柴油转化率

A Simultaneous Cartoon-Texture Image Segmentation and Image Decomposition Method

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Electronics 2020年第5期29卷 906-915页

作者： LI Yafeng ZHAO Qijun ZHANG Wenbo fan Pan ZHANG Renrui sun Jieqi LI jing School of Computer Science and Technology Baoji University of Arts and Science College of Computer Science Sichuan University School of Information Science and Technology Tibet University School of Electronics Engineering and Computer Science Peking University

Image segmentation and image decomposition are fundamental problems in image *** decomposition methods for separating images into cartoon and texture components can effectively serve different image processing tasks because different components can be respectively treated in more effective way. However, image decomposition methods are currently simply taken as an independent preprocessing step, and particularly in image segmentation different effects of cartoon and texture components have not been *** paper presents a novel simultaneous cartoon-texture image segmentation and image decomposition method to boost the performance of both segmentation and decomposition. We design a fast alternating optimization algorithm to solve the proposed model. Experimental results demonstrate the outstanding performance of the proposed method on both image segmentation and image decomposition.

关键词： Image segmentation Image decomposition Variational model Dictionary learning

A Trusted Multi-Task Distribution Mechanism for Internet of Vehicles Based on Smart Contract

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

China Communications 2023年第4期20卷 212-226页

作者： Xujie Li Yuan Xu jing Tang Ying sun Shaoshuai fan Fei Shen College of Computer and Information Hohai UniversityNanjing 210098China State Key Laboratory of Networking and Switching Technology Beijing University of Posts and TelecommunicationsBeijing 100876China School of Information Engineering Jiangsu Open UniversityNanjing 210017China Shanghai Institute of Microsystem and Information Technology Chinese Academy of SciencesShanghai 200050China

In this paper,a trusted multi-task distribution mechanism for Internet of Vehicles based on smart contract is proposed to improve the security and efficiency for the task distribution in Internet of ***,a three-tier trusted multi-task distribution framework is presented based on smart *** smart contract will be triggered by the task *** the important part of the smart contract,the task distribution algorithm is stored on the blockchain and run *** the process of the task distribution,the cost of the task distribution and the system stability play a critical ***,the task distribution problem is formulated to minimize the cost of the task distribution whilst maintaining the stability of the system based on Lyapunov ***,this problem is a mixed integer nonlinear programming problem with NP-hard *** tackle this,the optimization problem is decomposed into two sub problems of computing resource allocation and task distribution decision,and an effective task distribution algorithm is *** results show that the proposed algorithm can effectively improves system performance.

关键词： task distribution resource allocation Lyapunov optimization smart contract

A review of hydrogels used in endoscopic submucosal dissection for intraoperative submucosal cushions and postoperative management

在线全文

学校读者我要写书评

暂无评论

Regenerative Biomaterials 2023年第1期10卷 1261-1276页

作者： Zhihong Chen Jie Ding Chengheng Wu Dan Wei jing sun Hongsong fan Zhenzhen Guo National Engineering Research Center for Biomaterials College of Biomedical EngineeringSichuan UniversityChengduSichuan 610064China Institute of Regulatory Science for Medical Devices Sichuan UniversityChengduSichuan 610064China Department of Gastroenterology Sichuan Province People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan 610072China

Endoscopic submucosal dissection(ESD)has been clinically proved to have prominent advantages in the treatment of early gastrointestinal cancers over traditional surgery,including less trauma,fewer complications,a quicker recovery and lower *** the procedure of ESD,appropriate and multifunctional submucosal injected materials(SIMs)as submucosal cushions play an important role,however,even with many advances in design strategies of SIMs over the past decades,the performance of the submucosal cushions with postoperative management function seems to be still *** this review,we gave a brief historical recount about the clinical development of SIMs,then some common applications of hydrogels used as SIMs in ESD were summarized,while an account of the universal challenges during ESD procedure was also *** one step further,some cutting-edge functional strategies of hydrogels for novel applications in ESD were ***,we concluded the advantages of hydrogels as SIMs for ESD as well as the treatment dilemma clinicians faced when it comes to deeply infiltrated lesions,some technical perspectives about linking the clinical demand with commercial supply were also *** the basic elements of SIMs used in ESD surgery and the corresponding postoperative management requirements,this review could be a good reference for relevant practitioners in expanding the research horizon and improving the well-being index of patients.

关键词： hydrogels biopolymer gastrointestinal cancers submucosal injected materials postoperative management

Study on precipitation and transition mechanisms from the magnetic properties of silicon steel during annealing

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2014年第4期21卷 379-387页

作者： Yong-fei fan Hao Yu jing sun Pan Tao Cheng-hao Song Xun Zeng School of Materials Science and Engineering University of Science and Technology Beijing

Precipitates play an important role in determining the mechanical and magnetic properties of silicon steel. This paper aims to investigate the growth kinetics of precipitates in commercial silicon steel by analyzing its magnetic properties during isothermal annealing at 200℃. The growth of precipitates was studied by optical microscopy, scanning electron microscopy, transmission electron microscopy, and magnetic measurements. In combination with the coercive field and initial susceptibility, this technique offers the advantage of being non-destructive and providing quantitative information about the number, mean radius of precipitates, and fraction of transformation. An ob- served decrease in the number of precipitated particles indicates that the transformation starts from particles of appreciable initial size.

关键词： silicon steel precipitation growth kinetics magnetic properties isothermal annealing

Discovering myeloid cell heterogeneity in the lung by means of next generation sequencing

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2019年第4期6卷 354-363页

作者： jing-jing Ji Jie fan Department of Surgery University of Pittsburgh School of MedicinePittsburghPA 15213USA Department of Pathophysiology Southern Medical UniversityGuangzhou 510515China Research and Development Veterans Affairs Pittsburgh Healthcare SystemPittsburghPA 15240USA McGowan Institute for Regenerative Medicine University of PittsburghPittsburghPA 15219USA

The lung plays a vital role in maintaining homeostasis,as it is responsible for the exchange of oxygen and carbon *** homeostasis is maintained by a network of tissue-resident cells,including epithelial cells,endothelial cells and *** cells of the innate immune system and epithelial cells form a critical barrier in the *** developed unbiased next generation sequencing(NGS)has revealed cell heterogeneity in the lung with respect to physiology and pathology and has reshaped our *** phenotypes and distinct gene signatures have been identified,and these new findings enhance the diagnosis and treatment of lung ***,we present a review of the new NGS findings on myeloid cells in lung development,homeostasis,and lung diseases,including acute lung injury(ALI),lung fibrosis,chronic obstructive pulmonary disease(COPD),and lung cancer.

关键词： Acute lung injury Lung cancer Lung disease Lung development Single-cell RNA sequencing

The aging behavior,microstructure and mechanical properties of AlN/AZ91 composite

在线全文

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2023年第7期11卷 2458-2468页

作者： Yunxia sun Changlin Yang Bin Zhang Jianfeng fan Hongxiang Li Tianhao Zhao jing Li State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’anShaanxi 710072PR China Yangtze River Delta Research Institute of NPU TaicangJiangsu 215400PR China Key Laboratory of Interface Science and Engineering in Advanced Materials Ministry of EducationTaiyuan University of TechnologyTaiyuan 030024PR China State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing 100083PR China

Microstructure evolution and mechanical properties of the aging treated AlN/AZ91 composites were systematically investigated by optical microscopy(OM),high resolution scanning electron microscopy(HRSEM)with an energy dispersive spectrum(EDS),and high-angle annular dark field scanning transmission electron microscopy(HAADF-STEM).The results show that the higher fracture elongation(14±1%)and ultimate tensile strength(275±6 MPa)were simultaneously obtained in the peak-aged AlN/AZ91 *** with AZ91 matrix alloy,the strength was increased by about 44%and the elongation was approximately five times higher,which mainly attributed to the precipitation of nano-sizedγ-Mg_(17)Al_(12)phase and the activation of non-basal slip systems induced by in-situ AlN particles at room ***,the in-situ formation of AlN reinforcements consumed part of Al element in the matrix alloy,which resulted into the volume fraction decreasing ofγ-Mg_(17)Al_(12)precipitates,and then the age hardening and strengthening efficiency were reduced in the AlN/AZ91 *** the other hand,the mismatch of thermal expansion coefficient between AlN particles and AZ91 matrix generated high density dislocations around AlN particles,which promoted the precipitation ofγ-Mg_(17)Al_(12)phase,and then the peak aging time and temperature were decreased.

关键词： Magnesium matrix composites In-situ AlN particles Aging behavior Microstructure Mechanical properties

Synthesis,Structure and Luminescence of Zn_(4.5)Cu_3 Heteronuclear Coordination Polymer Comprising Macrocyclic Oxamide and 5-Sulfosalicylic Ion

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2010年第4期26卷 501-504页

作者： sun Ya-qiu WANG jing fan Lan-lan GAO Dong-zhao Tianjin Key Laboratory of Structure and Performance for Functional Molecule College of Chemistry and Life Science Tianjin Normal University Tianjin 300387 P. R. China

The complex [Zn4.5（SSA）3（CuL）3（H2O）6]n was synthesized and structurally determined, where SSA is fully deprotonated 5-sulfosalicylic acid（CuL, H2L=2,3-dioxo-5,6,14,15-dibenzo-1,4,8,12-tetraazacyclo-pentadeca- 7,13-dien）. The title complex crystallized in the triclinic system with space group P1^-, a=1.19788（17） nm, b=1.4253（2） nm, c=2.2890（4） nm, α=90.211（2）°, ,β=93.076（2）°, γ=90.600（2）°. The complex displayed a 1D ladderlike chain. All these 1D chains were further interlinked via hydrogen bonds, resulting in a 2D architecture. The luminescent property of the compound was also discussed.

关键词： Heteronuclear complex Macrocyclic oxamide Luminescence