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Food Science and Human Wellness 2024年第4期13卷 2060-2067页

作者： Yong Fang Tianhang Huang jian Wu Xieqi Luo Fengjiao Fan Peng Li jian Ding Xinyang sun College of Food Science and Engineering Nanjing University of Finance and Economics/Collaborative Innovation Center for Modern Grain Circulation and SafetyNanjing 210023China Laboratory of Neurodegenerative and Neuroinjury Diseases Wuxi School of MedicineJiangnan UniversityWuxi 214122China

Two selenium(Se)-containing peptides from Se-enriched rice,TSeMMM and SeMDPGQQ,possess neuroprotective potency against lead(Pb2+)-induced ***,the crosstalk between mRNA and microRNAs(miRNA)involved in the neuroprotection mechanism remains to be *** this study,RNA-sequencing and miRNA-sequencing were used to independently identify differentially expressed mRNAs and small RNAs profiles in Pb^(2+)-treated primary fetal rat cortical neurons and then the correlated miRNA-mRNA target pairs were *** was found that 34 mRNAs related to oxidative phosphorylation could be reversed by pretreatment of TSeMMM and *** protective effect of TSeMMM and SeMDPGQQ was mediated by upregulation of miR-107-3p,which downregulates the ATPase H+transporting V0 subunit e1(Atp6v0e1)mRNA level.A zebrafish model was applied to verify the relevance between the targeted mRNA and miRNA by real-time quantitative *** results indicated that miR-107-3p was a potential therapeutic target to achieve neuroprotection of Se-containing peptides via stimulation of Atp6v0e1.

关键词： Lead Se-containing peptides Neuroprotection miRNA

Formation mechanism of fault accommodation zones under combined stress in graben basin:Implications from geomechanical modeling

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Petroleum Science 2024年第1期21卷 54-76页

作者： Qi-Qiang Ren Jin-Liang Gao rong-Tao jiang Jin Wang Meng-Ping Li jian-Wei Feng Institute of Sedimentary Geology Chengdu University of TechnologyChengdu 610059SichuanChina PetroChina Research Institute of Petroleum Exploration and Development Beijing100083China jianghan Oilfield Oil and Gas Production Capacity Construction Management Center Chongqing408000China Sinopec Chongqing Fuling Shale Gas Exploration and Development Company Chongqing408000China College of Energy Chengdu University of TechnologyChengdu 610059SichuanChina School of Geoscience China University of Petroleum(East China)Qingdao 266580ShandongChina

A fault accommodation zone is a type of structure that is defined as regulating displacement and strain between faults *** numbers of fault accommodation zones are being identified in graben basins,indicating the potential exploration target and petroleum accumulation *** study aims to analyze the formation mechanism and development of fault accommodation zones under combined stress by a numerical simulation method considering geomechanical *** three-dimensional(3-D)seismic interpretation and fractal dimension method,exampled with the Dongxin fault zone,the fault activity and fault combination pattern were conducted to quantitatively characterize the activity difference in fault accommodation *** with mechanical experiment test,a geomehcanical model was established for fault accommodation zones in a graben *** the paleostress numerical simulations and structural physical simulation experiment,the developmental characteristics and genetic mechanism of fault accommodation zones were *** by multi movements and combined stresses,three significant tectonic evolution stages of the Dongxing Fault Zone(DXFZ)were distinguished:During the E_(s)^(3)sedimentary period,the large difference in the stress,strain,and rupture distribution in various faults were significant,and this stage was the key generation period for the prototype of the DXFZ,including the FAZ between large-scale *** the E_(s)^(2)sedimentary period,the EW-trending symmetric with opposite dipping normal faults and the NE-SW trending faults with large scale were furtherly *** junction area of two secondary normal faults were prone to be ruptured,performing significant period for inheriting and developing characteristics of fault accommodation *** the Es1 sedimentary period,the high-order faults in the DXFZ exhibited the obvious fault depressions and strike-slip activity,and the fault accommodation zones were

关键词： Fault accommodation zone Graben basin Fault activity Tectonic physical simulation experiment Finite element numerical simulation Dongxin fault zone

The NAC transcription factor LuNAC61 negatively regulates fiber development in flax (Linum usitatissimum L.)

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Journal of Integrative Agriculture 2024年第3期23卷 795-805页

作者： Dongwei Xie Jing Li Wan Li Lijun sun Zhigang Dai Wenzhi Zhou jianguang Su jian sun School of Life Sciences Nantong UniversityNantong 226019China Institute of Crop Cultivation and Tillage Heilongjiang Academy of Agricultural SciencesHarbin 150086China Institute of Bast Fiber Crops Chinese Academy of Agricultural SciencesChangsha 410221China jiangsu Sanshu Biotechnology Co.Ltd. Nantong 226001China

Flax is a crucial fiber crop that exhibits excellent textile properties and serves as a model plant for investigating phloem fiber development. The regulation of multiple genes significantly influences fiber development, notably involving NAC(NAM, ATAF1/2, CUC2) transcription factors in forming the fiber secondary cell wall(SCW).Overexpression of LuNAC61 in flax resulted in sparse top meristematic zone leaves and significantly reduced stem cellulose content. Scanning electron microscopy and staining observations revealed a significant reduction in fiber bundles. β-Glucuronidase(GUS) staining analysis demonstrated high activity of the LuNAC61 promoter in the bast fibers of the flax stem. Additionally, several members of the LuPLATZ and LuCesA families exhibited significant coexpression with LuNAC61. Subcellular localization indicated the presence of LuPLATZ24 protein in the nucleus and cytoplasm, LuNAC61 protein exclusively in the nucleus, and LuCesA10 in the nucleus and endoplasmic reticulum. LuPLATZ24 positively regulates LuNAC61, whereas LuNAC61 negatively affects LuCesA10, suggesting the involvement of a metabolic network in regulating flax fiber development. In conclusion, this study provides a critical opportunity for a comprehensive and in-depth analysis of the mechanisms governing flax fiber development and the potential use of biotechnology to enhance flax fiber yield.

关键词： flax fiber development Lu NAC61 gene function gene interaction

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钻井法凿井废弃泥浆固化的实验研究

煤炭工程 2007年第12期39卷 64-66页

作者：孙建荣煤炭科学研究总院建井分院北京100013

文章分析了泥浆固化机理,并在实验室内,对掺入数种外加剂的现场循环泥浆达到成型后的实块进行了针入度测定和抗压强度测定实验,筛选出钻井废弃泥浆固化处理配方。

关键词：钻井泥浆固化机理外加剂

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严寒地区煤矿地面生产系统采暖方案研究

煤炭工程 2021年第10期53卷 40-43页

作者：孙建荣国家能源集团神华北电胜利能源有限公司内蒙古锡林浩特026000

分析了北方严寒地区煤矿地面生产系统火灾隐患和消防水系统稳定运行的重要性。结合现场调研分析了北方严寒地区煤矿地面生产系统采暖的现状和消防系统面临的风险,重点针对输煤系统、筛分破碎系统、储煤系统等的隔热和采暖方案进行了分... 详细信息

分析了北方严寒地区煤矿地面生产系统火灾隐患和消防水系统稳定运行的重要性。结合现场调研分析了北方严寒地区煤矿地面生产系统采暖的现状和消防系统面临的风险,重点针对输煤系统、筛分破碎系统、储煤系统等的隔热和采暖方案进行了分析论证,并提出配置具有温度调节、故障诊断、节能分析等功能的智能供热管理系统,通过强化现场的硬件设施和管理的软件系统来确保采暖系统的稳定运行,进而保证消防系统稳定运行。

关键词：严寒地区煤矿采暖消防地面生产系统

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地面预注浆中压水试验的研究与应用

煤炭技术 2014年第7期33卷 115-117页

作者：孙建荣北京中煤矿山工程有限公司北京100013 煤矿深井建设技术国家工程实验室北京100013

经多年井筒地面预注浆工程的实践,研究探索出适合地面预注浆的大段高、高压力的压水试验方法,通过压水试验计算含水层渗透系数,并预测含水层井筒涌水量,其结果与井筒下凿实际涌水量相吻合,可以作为评价井筒注浆效果的依据,也可以作为制... 详细信息

经多年井筒地面预注浆工程的实践,研究探索出适合地面预注浆的大段高、高压力的压水试验方法,通过压水试验计算含水层渗透系数,并预测含水层井筒涌水量,其结果与井筒下凿实际涌水量相吻合,可以作为评价井筒注浆效果的依据,也可以作为制定井筒施工技术措施的依据。

关键词：地面预注浆压水试验渗透系数井筒涌水量

Sub-10-nm-sized Au@AuxIr1-x metal-core/alloy-shell nanoparticles as highly durable catalysts for acidic water splitting

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National Science Review 2024年第4期11卷 130-140页

作者： Huimin Wang Zhe-ning Chen Yuanyuan Wang Dongshuang Wu Minna Cao Fanfei sun rong Cao State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences University of Chinese Academy of Sciences School of Materials Science and Engineering Nanyang Technological University Shanghai Synchrotron Radiation Facility Shanghai Institute of Applied Physics Chinese Academy of Sciences Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China

The absence of efficient and durable catalysts for oxygen evolution reaction（OER） is the main obstacle to hydrogen production through water splitting in an acidic ele ***,we report a controllable synthesis method of surface IrOxwith changing Au/Ir compositions by constructing a range of sub-10-nm-sized core-shell nanocatalysts composed of an Au core and AuxIr1-xalloy *** particular,Au@Au0.43Ir0.57exhibits 4.5 times higher intrinsic OER activity than that of the commercial Ir/*** X-ray-based spectroscopies,electron microscopy and density functional theory calculations revealed a balanced binding of reaction intermediates with enhanced *** water-splitting cell using a load of 0.02 mgIr/cm2of Au@Au0.43Ir0.57as both anode and cathode can reach 10 mA/cm2at 1.52 V and maintain activity for at least194 h,which is better than the cell using the commercial couple Ir/C‖Pt/C（1.63 V,0.2 h）.

关键词： controllable synthesis of surface IrOx oxygen evolution reaction acidic water splitting catalytic stability transition metal catalysts

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钻注平行作业注浆液对泥浆影响实验研究

中国矿业 2010年第10期19卷 105-107页

作者：孙建荣北京中煤矿山工程有限公司北京100013

针对钻井法和注浆法平行作业凿井过程中出现的注浆液侵污钻井泥浆、影响正常钻进问题开展了室内试验研究。本文通过实验,分析了注浆液对钻井泥浆各项性能参数的影响,并提出了建立泥浆监测系统等预防措施。

关键词：钻注平行作业注浆液泥浆

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基于露天煤矿剥离定额的设备选型经济性研究

煤炭工程 2021年第1期53卷 23-27页

作者：孙建荣国家能源集团神华北电胜利能源有限公司内蒙古锡林浩特026000

为了降低露天煤矿生产成本,提高市场竞争力,研究了露天矿设备型号与采剥费用之间的关系。基于《煤炭工业露天剥离工程综合预算定额》,开展了开采、运输、平整等设备的经济性分析。根据煤矿土石方硬度、运距、重车上坡、重车下坡等不同工... 详细信息

为了降低露天煤矿生产成本,提高市场竞争力,研究了露天矿设备型号与采剥费用之间的关系。基于《煤炭工业露天剥离工程综合预算定额》,开展了开采、运输、平整等设备的经济性分析。根据煤矿土石方硬度、运距、重车上坡、重车下坡等不同工况,编制了不同型号的电铲(或液压反铲)、自卸卡车、推土机等设备各种工况下的定额单价表,绘制价格曲线图,进而直观地反映各种型号设备的经济性,并结合露天煤矿采矿方案开展了开采、运输、平整等设备组合方案的综合价格分析,参照图表价格曲线实现设备组合方案的优选,为露天煤矿设备选型提供经济参考依据。

关键词：露天煤矿设备选型剥离定额经济性

反井钻机先导孔钻进常见事故原因分析及处理措施

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煤炭工程 2014年第8期46卷 45-47页

作者：孙建荣北京中煤矿山工程有限公司北京100013

论文论述了先导孔钻进在反井钻井施工中的作用,对先导孔钻进中常见事故进行了原因分析,重点对反井钻进先导孔施工过程中可能发生的缩颈、塌孔、卡钻、偏斜超限、漏失等主要常见事故进行了深入分析,并在此基础上,给出了指导性处理预案与... 详细信息

论文论述了先导孔钻进在反井钻井施工中的作用,对先导孔钻进中常见事故进行了原因分析,重点对反井钻进先导孔施工过程中可能发生的缩颈、塌孔、卡钻、偏斜超限、漏失等主要常见事故进行了深入分析,并在此基础上,给出了指导性处理预案与办法,对反井钻进先导孔施工具有一定指导意义。

关键词：反井钻机先导孔缩孔塌孔卡钻偏斜率