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A two-dimensional double layer-averaged model of hyperconcentrated turbidity currents with non-Newtonian rheology

International Journal of Sediment Research 2023年第6期38卷 794-810页

作者： yining sun Ji Li Zhixian Cao Alistair George Liam Borthwick State Key Laboratory of Water Resources Engineering and Management Wuhan University Zienkiewicz Centre for Computational Engineering Faculty of Science and EngineeringSwansea University Institute for Infrastructure and Environment University of Edinburgh School of Engineering Computing and MathematicsUniversity of Plymouth

Hyperconcentrated turbidity currents typically display non-Newtonian characteristics that influence sediment transport and morphological evolution in alluvial ***,hydro-sedimentmorphological processes involving hyperconcentrated turbidity currents are poorly understood,with little known about the effect of the non-Newtonian *** current paper extends a recent twodimensional double layer-averaged model to incorporate non-Newtonian constitutive *** extended model is benchmarked against experimental and numerical data for cases including subaerial mud flow,subaqueous debris flow,and reservoir turbidity *** computational results agree well with observations for the subaerial mud flow and independent numerical simulations of subaqueous debris *** between the non-Newtonian and Newtonian model results become more pronounced in terms of propagation distance and sediment transport rate as sediment concentration *** model is then applied to turbidity currents in the Guxian Reservoir planned for middle Yellow River,China,which connects to a tributary featuring hyperconcentrated sediment-laden *** non-Newtonian model predicts slower propagation of turbidity currents and more significant bed aggradation at the confluence between the tributary Wuding River and the Yellow River in the reservoir than its Newtonian *** difference in model performance could be of considerable importance when optimizing reservoir operation schemes.

关键词： Double layer-averaged model Non-Newtonian rheology Mud flow Reservoir turbidity current Yellow River

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Single-atom Catalysts Based on Layered Double Hydroxides

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Chemical Research in Chinese Universities 2022年第5期38卷 1185-1196页

作者： FAN Kui sun yining XU Pengcheng GUO Jian LI Zhenhua SHAO Mingfei State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical TechnologyBeijing 100029P.R.China

Single-atom catalysts(SACs)have attracted much attention for their superior catalytic performance in various *** has been widely accepted that the selection of appropriate substrates is crucial to the fabrication and application of *** double hydroxides(LDHs)have been developed as one of the promising substrates for single-atoms due to their unique adjustable supramolecular *** this review,we comprehensively sort out the research of SACs based on *** analyzing the characteristics of LDHs and the single-atoms,respectively,the preparation strategies of SACs by using LDHs are *** applications as efficient catalysts in electrocatalysis,photocatalysis and thermal catalysis are then ***,we summarize the opportunities and challenges for the rational design and application expansion of SACs based on LDHs in the future.

关键词： Layered double hydroxide Single-atom catalyst Synthesis Catalysis

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A novel peptide-based probe^(99m)Tc-PEG_(6)-RD-PDP2 for the molecular imaging of tumor PD-L2 expression

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Chinese Chemical Letters 2022年第7期33卷 3497-3501页

作者： Qi Luo Yunwei Zhang Zihua Wang yining sun Linqing Shi Yue Yu Jiyun Shi Zhiyuan Hu Fan Wang Guangzhou Laboratory Guangzhou 510005China Medical Isotopes Research Center and Department of Radiation Medicine State Key Laboratory of Natural and Biomimetic DrugsSchool of Basic Medical SciencesPeking UniversityBeijing 100191China Fujian Provincial Key Laboratory of Brain Aging and Neurodegenerative Diseases School of Basic Medical SciencesFujian Medical UniversityFuzhou 350122China Key Laboratory of Protein and Peptide Pharmaceuticals CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China CAS Key Laboratory of Standardization and Measurement for Nanotechnology CAS Key Laboratory for Biomedical Effects of Nanomaterials and NanosafetyCAS Center for Excellence in NanoscienceNational Center for Nanoscience and Technology of ChinaBeijing 100190China

Tumor-related PD-L2 expression is associated with the clinical efficacy of PD-1/PD-L1 blockade ***-L2-specific imaging can help selecting patients for appropriate *** this study,a PD-L2-targeting peptide(PDP2)was screened by the one-bead one-compound combinatorial library *** the retro-inverso D-peptide of PDP2(RD-PDP2)and PEGylation strategies,we developed a novel Tc-99m-labeled PD-L2-targeting peptide as a SPECT tracer(^(99m)Tc-PEG_(6)-RD-PDP2)for imaging of tumor PD-L2 *** radiolabeling yield of ^(99m)Tc-PEG_(6)-RD-PDP2 was greater than 95%by the standard HYNIC/tricine/TPPTS labeling procedure.^(99m)Tc-PEG_(6)-RD-PDP2 displayed high PD-L2-binding specificity both in vitro and in ***/CT imaging with^(99m)Tc-PEG_(6)-RD-PDP2 showed that the A549-PD-L2tumors were clearly visualized,whereas the signals in PD-L2-negative A549 tumors were much *** vivo blocking study suggested that the tumor uptake of^(99m)Tc-PEG_(6)-RD-PDP2 was PD-L2 specifically mediated.^(99m)Tc-PEG_(6)-RD-PDP2 is a promising SPECT probe for the non-invasive imaging of tumor PD-L2expression and has a great potential in guiding the anti-PD-1 or anti-PD-L1 immunotherapy of cancer.

关键词： PD-L2 Peptide probe SPECT imaging Immunotherapy

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Associations among cerebral microbleeds, cerebral large-artery diseases and endothelial function

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Chinese Medical Journal 2014年第18期127卷 3204-3208页

作者： Peng Qing Huang yining sun Wei Xing Haiying Department of Neurology Peking University First Hospital Beijing 100034 China

Background Endothelial dysfunction is not only an early stage of atherosclerosis,but also involved in the pathogenesis of cerebral small-vessel *** with cerebral microbleeds （CMBs） may have arteriolosclerosis as well as systemic ***,little is known about the associations among CMBs,atherosclerosis of cerebral large arteries,and endothelial *** study aimed to investigate the relationships among *** This was a cross-sectional *** patients hospitalized in Peking University First Hospital with acute ischemic stroke were enrolled consecutively between November 1,2007 and January 31,*** subjects underwent transcranial Doppler and carotid color duplex ultrasonography to record the intima-media thickness （IMT） of common carotid artery,carotid plaque,and cerebral artery *** magnetic resonance imaging （MRI） routine sequences and gradient recall-echo T2＊-weighted imaging were performed to count CMBs with clinical data *** function was evaluated using flow-mediated dilation （FMD） and nitroglycerin-mediated dilation （NMD） of the brachial *** and NMD were examined by an experienced vascular sonographer using a high-resolution *** Thirty cases （33.3%） had CMBs with counts ranging from 1 to *** FMD （（9.9＆#177;4.8）% vs.（15.2＆#177;7.4）%,P=0.001） and NMD （（13.7＆#177;6.1）% vs.（19.0＆#177;7.4）%,P=0.001） were significantly decreased in CMB-positive patients than in CMB-negative *** significant relationships were demonstrated between CMBs and intracranial and/or extracranial artery *** frequencies of CMBs in patients with IMT≥1.0 mm,carotid plaque,and extracranial artery stenosis were 37.5%,39.4%,and 47.6% respectively,with no significant difference,but much higher than in patients with IMT 〈1.0 mm （5%,P 〈0.05）.In Logistic regression analysis,impaired FMD （OR=5.783,95% CI 1.652-6.718,P=0.007） and high pulse pressure （OR=6.228,95% CI 1.594-3.891,P=0.009）

关键词： cerebral small vessel diseases brain ischemia endothelial function magnetic resonance imaging

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Characteristics of gas-solid micro fluidized beds for thermochemical reaction analysis

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Carbon Resources Conversion 2020年第1期3卷 203-218页

作者： Zhennan Han Junrong Yue Xi Zeng Jian Yu Fang Wang Shaozeng sun Hong Yao Guangqian Luo Xuejing Liu yining sun Fu Ding Liangliang Fu Lei Shi Kangjun Wang Jiebin Yang Shaonan Wang Xueqing Chen Dingrong Bai Guangwen Xu Key Laboratory on Resources Chemicals and Material of Ministry of Education Shenyang University of Chemical TechnologyShenyang 110142China The State Key Laboratory of Multi-phase Complex System Institute of Process EngineeringChinese Academy of ScienceBeijing 100190China Combustion Engineering Research Institute School of Energy Science and EngineeringHarbin Institute of TechnologyHarbin 150001China State Key Laboratory of Coal Combustion Huazhong University of Science and TechnologyWuhan 430074China National Institute of Measurement and Technology Chengdu 610021China

Fuel conversion and clean energy reaction systems involve a variety of catalytic and non-catalytic gas-solid thermochemical reactions.A good understanding of the correct reaction mechanism and kinetics,as well as the profiles of reaction products,is of great significance to the development,design,and operation of such reaction *** micro fluidized bed reaction analysis provides an efficient and reliable method to acquire this essential information with low capital and operating costs,low energy consumption and enhanced *** paper provides an overview of the system and its characteristics for the micro fluidized bed reaction analyzer that has been well proven to be a reliable new approach as well as an instrument for characterizing various gas-solid thermochemical reactions.

关键词： Micro fluidized bed Reaction kinetic analysis Isothermal differential reactor Thermochemical reaction characterization

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A Morphological Classification Method of ECG ST-Segment Based on Curvature Scale Space

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Journal of Biosciences and Medicines 2015年第9期3卷 38-43页

作者： Fusong Hu Chengtao Li Yongliang Zhang Dan Jin Zuchang Ma yining sun Jingzhi Wang Department of Automation University of Science and Technology of China Hefei China Research Center for Information Technology of Sports and Health Institute of Intelligent Machines Chinese Academy of Sciences Hefei China

Aomalous changes in the ST segment, including ST level deviation and ST shape change, are the major parameters in clinical electrocardiogram (ECG) diagnosis of myocardial ischemia. Automatic detection of ST segment morphology can provide a more accurate evidence for clinical diagnosis of myocardial ischemia. In this paper, we proposed a method for classifying the shape of the ST-segment based on the curvature scale space (CSS) technique. First, we established a reference ST set and preprocessed the ECG signal by using the CSS technique. Then, the corner points in the ST-segment were detected at a high scale of the CSS and tracked through multiple lower scales, in order to improve its localization. Finally, the current beat of ST morphology can be distinguished by the corner points. We applied the developed algorithm to the ECG recordings in European ST-T database and QT database to validate the accuracy of the algorithm. The experimental results showed that the average detection accuracy of our algorithm was 91.60%. We could conclude that the proposed method is able to provide a new way for the automatic detection of myocardial ischemia.

关键词： Myocardial Ischemia Electrocardiogram ST Shape Classification Curvature

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井下无线传感器网络AODV和DSDV协议的仿真对比

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传感技术学报 2009年第10期22卷 1515-1518页

作者：吴全玉孙怡宁中国科学院合肥智能机械研究所安徽省仿生感知与先进机器人技术重点实验室合肥230031 中国科学技术大学自动化系合肥230027 皖西学院机械与电子工程系安徽六安237012

通过分析当前煤矿安全监测无线传感器网络的路由特点及其对应的掘进工作面典型的系统方案,比较当前无线传感网络中比较经典的AODV和DSDV路由协议,为了考察这两种路由协议在矿井下的性能,使用NS2网络仿真软件的Shad-owing模式,选取包成... 详细信息

通过分析当前煤矿安全监测无线传感器网络的路由特点及其对应的掘进工作面典型的系统方案,比较当前无线传感网络中比较经典的AODV和DSDV路由协议,为了考察这两种路由协议在矿井下的性能,使用NS2网络仿真软件的Shad-owing模式,选取包成功投递端到端的平均延时、包成功投递率、路由协议负载这三个衡量指标对AODV与DSDV路由协议进行了性能评估,研究结果表明在节点相对少的掘进巷道场景下DSDV协议表现出较好的特点和很好的鲁棒性,为满足井下实时监测网络的应用需求提供一种方案。

关键词：井下安全监测无线传感器网络AODV和DSDV协议网络仿真

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关注白内障术后干眼

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中华眼视光学与视觉科学杂志 2021年第7期23卷 486-490页

作者：孙一宁陈蔚温州医科大学眼视光学院 325000

手术干预是治疗白内障引起视力下降最有效的方法,能够安全有效地帮助患者重获光明。随着现代医学的发展,患者对视觉质量的要求逐渐提高,术后并发症同样成为白内障手术治疗需要解决的热点问题,干眼是其中最受关注的问题之一。笔者就可能... 详细信息

手术干预是治疗白内障引起视力下降最有效的方法,能够安全有效地帮助患者重获光明。随着现代医学的发展,患者对视觉质量的要求逐渐提高,术后并发症同样成为白内障手术治疗需要解决的热点问题,干眼是其中最受关注的问题之一。笔者就可能导致白内障术后干眼的因素和目前存在的治疗手段进行探讨,结合已经存在的和尚在研究的围手术期预防手段,进一步加深临床医师对防治白内障术后干眼重要性的认识。

关键词：白内障手术干眼围手术期预防

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Reed-Solomon码概率软译码算法增强技术

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中国科学：信息科学 2021年第8期51卷 1331-1344页

作者：孙怡宁黄秋胡剑浩电子科技大学通信抗干扰技术国家级重点实验室成都611731

基于概率计算的Chase算法可以在保证译码性能的情况下,大幅度降低软译码的复杂度,使得RS软译码算法得到实际应用.然而,概率Chase算法的时间复杂度会随着测试码字个数的增加而增长;在高阶调制下, SSCA算法产生测试码字时的搜索范围会随... 详细信息

基于概率计算的Chase算法可以在保证译码性能的情况下,大幅度降低软译码的复杂度,使得RS软译码算法得到实际应用.然而,概率Chase算法的时间复杂度会随着测试码字个数的增加而增长;在高阶调制下, SSCA算法产生测试码字时的搜索范围会随着调制阶数的增加呈指数增长,从而增大了硬件存储开销.为降低时间复杂度,本文提出了提前输出算法,不需要产生所有的测试码字即可实现成功译码.仿真结果表明该算法可以在逼近原算法误帧率性能的同时将时间复杂度最多降低为原来的近1/τ(τ为测试码字个数).针对SSCA算法存储的压力,本文通过确定搜索半径辅助的选择方法来减小搜索范围.仿真结果表明,提出的3σ-SSCA算法仅以少量性能损失为代价可将测试码字单个符号的搜索范围由q (q为调制阶数)个缩小为个位数.

关键词： RS码 Chase算法概率计算提前输出算法搜索半径辅助的选择方法

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社会资本、财务弹性储备水平与企业资本结构

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财会通讯（下） 2019年第11期 107-111页

作者：孙艺宁彭颖四川大学锦江学院会计学院西南财经大学天府学院

本文选择2009-2017年沪深两市A股制造业上市企业为研究样本,利用其经验数据实证检验财务弹性储备水平对企业资本结构的作用与影响机理,更进一步对社会资本的调节作用进行分析,研究发现出:财务弹性储备水平越高,企业就越倾向于采取资产... 详细信息

本文选择2009-2017年沪深两市A股制造业上市企业为研究样本,利用其经验数据实证检验财务弹性储备水平对企业资本结构的作用与影响机理,更进一步对社会资本的调节作用进行分析,研究发现出:财务弹性储备水平越高,企业就越倾向于采取资产负债率越低的资本结构策略;社会资本负向调节了财务弹性储备水平与企业资本结构策略之间的相关性。

关键词：财务弹性储备水平资本结构社会资本

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