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肺成纤维细胞在肺损伤修复中的研究进展

中国细胞生物学学报 2024年第5期46卷 881-891页

作者：杨迪张家柱隋鹏飞中国科学院分子细胞科学卓越创新中心/生物化学与细胞生物学研究所上海200031

作为肺间质细胞的重要组成部分,成纤维细胞参与细胞外基质合成,维持肺部结构稳定,并为肺内干细胞的功能调控提供干细胞龛。在稳态以及损伤修复过程中,成纤维细胞通过旁分泌信号与肺内多种细胞互作,维持组织结构完整。在病理条件下,成纤... 详细信息

作为肺间质细胞的重要组成部分,成纤维细胞参与细胞外基质合成,维持肺部结构稳定,并为肺内干细胞的功能调控提供干细胞龛。在稳态以及损伤修复过程中,成纤维细胞通过旁分泌信号与肺内多种细胞互作,维持组织结构完整。在病理条件下,成纤维细胞则会发生异常激活,其主要通过分泌胶原蛋白和纤维蛋白参与组织纤维化,影响多种肺部疾病的发生发展过程。鉴于成纤维细胞在肺的稳态维持和损伤修复过程中的重要性,该综述系统性地归纳总结了肺成纤维细胞研究的最新进展。此外还提出了未来肺成纤维细胞研究中值得探讨的问题,旨在为解析肺部疾病的发病机制和寻找潜在治疗靶点提供新的思路。

关键词：肺成纤维细胞呼吸道干细胞细胞互作肺部疾病

Adsorptions of metal adatoms on graphene-like BC3 and their rich electronic properties： A first-principles study

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Chinese Physics B 2018年第9期27卷 550-557页

作者： pengfei sui Jiaqi Dai Yinchang Zhao Zhenhong Dai Department of Physics Yantai UniversityYantai 264005China Department of Physics. Renmin University of China Beijing 100872 China

Density functional calculations have been performed to investigate the adsorption of twenty two different kinds of metal adatoms on graphene-like BC3. In contrast to the graphene adsorbed with adatoms, the BC3 with adatoms shows many interesting properties.（1） The interaction between the metal adatoms and the BC3 sheet is remarkably strong. The Li, Na, K, and Ca possess the binding energies larger than the cohesive energies of their corresponding bulk metals.（2）The Li, Na, and K adatoms form approximately ideal ionic bonds with BC3, while the Be, Mg, and Ca adatoms form ionic bonds with BC3 with slight hybridization of covalent bonds. The Al, Ga, In, Sn, and all transition metal adatoms form covalent bonds with BC3.（3） For all the structures studied, there exhibit metal, half-metal, semiconducting, and spin-semiconducting behaviors. Especially, the BC3 with Co adatom shows a quantum anomalous Hall（QAH） phase with a Chern number of -1 based on local density approximation calculations.（4） For Li, Na, K, Ca, Ga, In, Sn, Ti, V, Cr,Ni, Pd, and Pt, there exists a trend that the adatom species with lower ionization potential have lower work function. Our results indicate the potential applications of functionalization of BC3 with metal adatoms.

关键词： density functional theory metal adatoms graphene-like BC sheet anomalous Hall conductivity

Co-and N-doped carbon nanotubes with hierarchical pores derived from metal-organic nanotubes for oxygen reduction reaction

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Journal of Energy Chemistry 2021年第2期30卷 49-55,I0002页

作者： Xuewan Wang Xiuan Xi Ge Huo Chenyu Xu pengfei sui Renfei Feng Xian-Zhu Fu Jing-Li Luo College of Materials Science and Engineering Shenzhen UniversityShenzhen 518060GuangdongChina Department of Chemical and Materials Engineering University of AlbertaEdmonton T6G 1H9AlbertaCanada Canadian Light Source Saskatoon S7N 2V3SaskatchewanCanada

Biomolecules with a broad range of structure and heteroatom-containing groups offer a great opportunity for rational design of promising electrocatalysts via versatile *** this study,uniform folic acid-Co nanotubes(FA-Co NTs) were hydrothermally prepared as sacrificial templates for highly porous Co and N co-doped carbon nanotubes(Co-N/CNTs) with well-controlled size and *** formation mechanism of FA-Co NTs was investigated and FA-Co-hydrazine coordination interaction together with the H-bond interaction between FA molecules was characterized to be the driving force for growth of one-dimensional *** distinct metal-ligand interaction afforded the resultant CNTs rich Co-N_x sites,hierarchically porous structure and Co nanoparticle-embedded conductive network,thus an overall good electrocatalytic activity for oxygen *** tests showed that Co-N/CNTs-900 promoted an efficient 4 e ORR process with an onset potential of 0.908 V ***,a limiting current density of 5.66 mA cm^(-2) at 0.6 V and a H_2 O_2 yield lower than 5%,comparable to that of 20%Pt/C ***,the catalyst revealed very high stability upon continuous operation and remarkable tolerance to methanol.

关键词： Folic acid Metal–organic nanotube Carbon nanotube In situ doping Oxygen reduction

Selective core-shell doping enabling high performance 4.6 V-LiCoO2

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Journal of Energy Chemistry 2024年第8期95卷 684-693页

作者： Yueming Xia Jianrui Feng Jinhui Li Yan Li Zhengfeng Zhang Xiaoqi Wang Jianli Shao Manling sui pengfei Yan Beijing Key Laboratory of Microstructure and Property of Solids College of Materials Science & Engineering Beijing University of Technology Petro China Research Institute of Petroleum Exploration & Development State Key Laboratory of Explosion Science and Technology Beijing Institute of Technology

Constructing robust surface and bulk structure is the prerequisite for realizing high performance high voltage LiCoO2（LCO）.Herein,we manage to synthesize a surface Mg-doping and bulk Al-doping coreshell structured LCO,which demonstrates excellent cycling ***-cell shows 94.2% capacity retention after 100 cycles at 3.0-4.6 V（***/Li+） cycling,and no capacity decay after 300 cycles for fullcell test（3.0-4.55 V）.Based on comprehensive microanalysis and theoretical calculations,the degradation mechanisms and doping effects are systematically *** the undoped LCO,high voltage cycling induces severe interfacial and bulk degradations,where cracks,stripe defects,fatigue H2 phase,and spinel phase are identified in grain *** the doped LCO,Mg-doped surface shell can suppress the interfacial degradations,which not only stabilizes the surface structure by forming a thin rock-salt layer but also significantly improves the electronic conductivity,thus enabling superior rate *** Al-doping can suppress the lattice "breathing" effect and the detrimental H3 to H1-3 phase transition,which minimizes the internal strain and defects growth,maintaining the layered structure after prolonged *** theoretical calculations,this work deepens our understanding of the doping effects of Mg and Al,which is valuable in guiding the future material design of high voltage LCO.

关键词： Doping effect Electron microscopy Failure mechanism High-voltage LiCoO2 Lithium-ion battery

Early-stage latent thermal failure of single-crystal Ni-rich layered cathode

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Journal of Energy Chemistry 2024年第9期96卷 578-587页

作者： Xiao Han Ruoyu Xu Yan Li Yang Ding Manchen Zhang Bo Wang Xiaoxing Ke Manling sui pengfei Yan Beijing Key Laboratory of Microstructure and Property of Solids Faculty of Materials and ManufacturingBeijing University of TechnologyBeijing 100124China Watt Laboratory Central Research InstituteHuawei Technologies Co.LTDShenzhen 518129GuangdongChina

High nickel content worsens the thermal stability of layered cathodes for lithium-ion batteries,raising safety concerns for their *** understanding the thermal failure process can offer valuable guidance for material optimization on thermal stability and new opportunities in monitoring battery thermal runaway(TR).Herein,this work comprehensively investigates the thermal failure process of a single-crystal nickel-rich layered cathode and finds that the latent thermal failure starts at∼120℃far below the TR temperature(225℃).During this stage of heat accumulation,sequential structure transition is revealed by atomic resolution electron microscopy,which follows the layered→cation mixing layered→LiMn_(2)O_(4)-type spinel→disordered spinel→rock *** progression occurs as a result of the continuous migration and densification of transition metal *** transition generates gaseous oxygen,initially confined within the isolated closed pores,thereby not showing any thermal failure phenomena at the *** temperature leads to pore growth and coalescence,and eventually to the formation of open pores,causing oxygen gas release and weight loss,which are the typical TR *** highlight that latent thermal instability occurs before the macro-level TR,suggesting that suppressing phase transitions caused by early thermal instability is a crucial direction for material *** findings can also be used for early warning of battery thermal runaway.

关键词： Thermal runaway Nickel-rich layered cathode Transmission electron microscopy Lithium-ion battery Phase transition

Highly crystalline Y3Al5O12:Ce3+ phosphor-in-silica glass ceramics for high-power solid-state lighting

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Journal of Rare Earths 2024年第11期42卷 2051-2057页

作者： Shisheng Lin Hang Lin Hongyi Yang pengfei Wang Ping sui Ju Xu Yao Cheng Yuansheng Wang Key Laboratory of Optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of Sciences Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China Xiamen Institute of Rare-earth Materials Haixi InstitutesChinese Academy of Sciences College of Chemistry and Materials Science Fujian Normal University

The pursuit of high-brightness solid-state lighting（SSL） stimulates the development of all-inorganic color converters with high *** is required that the fluorescent material is able to cope with the extreme condition generated from the irradiation of high-power-density excitation *** such,in this work,we developed a new composite color converter,i,e.,Y3Al5O12:Ce3+phosphor-in-silica glass ceramic(YAG:Ce3+PiSGC).Remarkably,the amorphous SiO2matrix spontaneously transforms into tetragonal SiO2crystallites during co-sintering with crystallization fraction reaching up to>90%（almost full ceramization）.The activation energy for crystallization Ecand Avrami index n of amorphous silica oxide are 298.5 kJ/mol and 1.71,indicating the diffusion-controlled glass crystallization *** fabricated prototype high-power phosphor-converted white light-emitting diode（pc-wLED） and phosphor-converted white laser diode（pc-wLD） based on YAG:Ce3+PiSGC show satisfactory photometric/colorimetric *** developed color co nverters have combined merits of environmental protection property,cost-effective manufacturing,good luminescent performance,and easy *** study highlights a new kind of opto-functional composite material and its application as an efficient color converter in high-power solid-state lightings.

关键词： Glass ceramics Laser-driven white light Rare earths White light-emitting diode Y3Al5O12:Ce3+

H3K36 Methylation Is Involved in Promoting Rice Flowering

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Molecular Plant 2013年第3期6卷 975-977页

作者： pengfei sui Jinlei Shi xueying Gao Wen-Hui Shen Aiwu -Dong State Key Laboratory of Genetic Engineering Institute of Plant Biology Department of Biochemistry School of Life Sciences Fudan University Shanghai 200433 RR. China Institut de Biologie Moleculaire des Plantes du CNRS Universite de Strasbourg 12 rue du General Zimmer 67084 Strasbourg Cedex France

Dear Editor, Histone H3 lysine 36 （H3K36） methylation is a conserved epigenetic mark in all eukaryotes （Berr et al., 2011; Wagner and Carpenter, 2012）. Reverse genetic analysis in Arabidopsis had uncovered a crucial role of H3K36 di- and tri-methylation （H3K36me2 and H3K36me3） in flowering-time regulation （reviewed in Berr et al., 2011）.

关键词：甲基化赖氨酸稻属

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公共图书馆与人口文化素质的耦合协调度研究

图书情报工作 2015年第22期59卷 39-44页

作者：隋鹏飞山东师范大学地理与环境学院济南250014 山东工商学院经济学院烟台264005

[目的 /意义]研究我国各地区的公共图书馆与人口文化素质协调程度和区域差异,对促进国家制定相应的协调发展政策,实现公共图书馆与人口文化素质协调发展具有重要意义。[方法/过程]结合耦合协调度模型方法,对我国各省市的公共图书馆与人... 详细信息

[目的 /意义]研究我国各地区的公共图书馆与人口文化素质协调程度和区域差异,对促进国家制定相应的协调发展政策,实现公共图书馆与人口文化素质协调发展具有重要意义。[方法/过程]结合耦合协调度模型方法,对我国各省市的公共图书馆与人口文化素质协调程度及区域差异进行定量分析。[结果/结论]结果表明我国的公共图书馆整体发展相对滞后;公共图书馆和人口文化素质耦合协调度虽然在整体上逐步提高,但有部分省市发展较慢;在空间分布上,公共图书馆和人口文化素质耦合协调度呈现按西部、中部、东北、东部顺序增强的趋势。

关键词：公共图书馆人口文化素质耦合协调度

Selective core-shell doping enabling high performance 4.6 V-LiCoO_(2)

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Journal of Energy Chemistry 2024年第8期95卷 684-693,I0015页

作者： Yueming Xia Jianrui Feng Jinhui Li Yan Li Zhengfeng Zhang Xiaoqi Wang Jianli Shao Manling sui pengfei Yan Beijing Key Laboratory of Microstructure and Property of Solids College of Materials Science&EngineeringBeijing University of TechnologyBeijing 100124China PetroChina Research Institute of Petroleum Exploration&Development Beijing 100083China State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China

Constructing robust surface and bulk structure is the prerequisite for realizing high performance high voltage LiCoO_(2)(LCO).Herein,we manage to synthesize a surface Mg-doping and bulk Al-doping coreshell structured LCO,which demonstrates excellent cycling ***-cell shows 94.2%capacity retention after 100 cycles at 3.0-4.6 V(***/Li^(+))cycling,and no capacity decay after 300 cycles for fullcell test(3.0-4.55 V).Based on comprehensive microanalysis and theoretical calculations,the degradation mechanisms and doping effects are systematically *** the undoped LCO,high voltage cycling induces severe interfacial and bulk degradations,where cracks,stripe defects,fatigue H2 phase,and spinel phase are identified in grain *** the doped LCO,Mg-doped surface shell can suppress the interfacial degradations,which not only stabilizes the surface structure by forming a thin rock-salt layer but also significantly improves the electronic conductivity,thus enabling superior rate *** Al-doping can suppress the lattice"breathing"effect and the detrimental H3 to H1-3 phase transition,which minimizes the internal strain and defects growth,maintaining the layered structure after prolonged *** theoretical calculations,this work deepens our understanding of the doping effects of Mg and Al,which is valuable in guiding the future material design of high voltage LCO.

关键词： Lithium-ion battery Doping effect Failure mechanism High-voltage LiCoO_(2) Electron microscopy