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The Research of Drug Risk Associated with supraventricular Tachycardia Based on the Openvigil Database

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The Research of Drug Risk Associated with Supraventricular T...

2023年度全国临床药理学学术论坛

作者： Weihong Chen Dongqin Huang Shaobin Li yuchao su Department of Anxi County Hospital

Objective:Through the openvigil database,assess medications that can cause supraventricular tachycardia（SVT） in order to offer a reference for their safety in clinical ***:Using the keyword "supraventricular tachycardia" in the openvigil database,the data from the first quarters of 2004 and 2023 were *** trade names and generic names were then queried in the RxNav database,and the proportions were *** diagrams were made,the proportional reporting ratios（PRR）,reporting odds ratios（ROR）,and Chiquared values were summarized for screening with DE≥30,PRR>2,and Chiquared>4 as *** hangzhou yiyao rational medication system,the SIDER database,and the literature database were used to assess the ***:Between the first quarter of 2004 and 2023,a total of 2,435 different types of drugs caused SVT,with a cumulative total of 22,375 adverse events reported for *** detailed investigation determined that salbutamol,paroxetine,formoterol,paclitaxel,venlafaxine,and theophylline were the drugs most likely to cause ***:Signal mining of adverse drug events from the openvigil database,through rigorous medical evaluation of the six drugs most likely to cause SVT,the results of the study can be a excellent early warning for the clinic.

关键词： supraventricular tachycardia Adverse reactions Data mining Medical evaluation Pharmacovigilance

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燃料电池混合动力叉车能量控制策略研究

新疆大学学报（自然科学版） 2018年第2期35卷 137-142,202页

作者：贠海涛徐煜超苏俊龙青岛理工大学汽车与交通学院山东青岛266520

为了解决内燃机叉车工作效率低、对环境产生污染,电动叉车充电时间长、工作时间短的问题,在综合比较分析各种动力组合与驱动形式利弊的基础上,提出了一种燃料电池混合动力叉车结构.针对燃料电池混合动力叉车的驱动系统,分别阐述了电池SO... 详细信息

为了解决内燃机叉车工作效率低、对环境产生污染,电动叉车充电时间长、工作时间短的问题,在综合比较分析各种动力组合与驱动形式利弊的基础上,提出了一种燃料电池混合动力叉车结构.针对燃料电池混合动力叉车的驱动系统,分别阐述了电池SOC控制和电池电压控制的能量管理策略,并通过仿真对控制方案进行了解释和验证.仿真结果表明:在不同的操作环境和电池状态下电池电压控制更好的满足叉车驱动系统的控制要求,可以更有效地抑制直流总线电压过冲.

关键词：燃料电池电池叉车转换器控制

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铁死亡诱导剂在结直肠癌中的研究进展

中国医学创新 2023年第34期20卷 180-184页

作者：陈伟鸿苏小苹苏宇超黄栋钦许永鹏福建省安溪县医院福建安溪362400

结直肠癌(colorectal cancer,CRC)是全球第三大常见癌症,传统治疗方案对CRC晚期患者的疗效不佳,因此,发现新的治疗策略可能有助于改善CRC患者的治疗和预后。铁死亡是一种铁依赖型调节性细胞死亡,其特征是铁水平和活性氧(reactive oxygen... 详细信息

结直肠癌(colorectal cancer,CRC)是全球第三大常见癌症,传统治疗方案对CRC晚期患者的疗效不佳,因此,发现新的治疗策略可能有助于改善CRC患者的治疗和预后。铁死亡是一种铁依赖型调节性细胞死亡,其特征是铁水平和活性氧(reactive oxygen species,ROS)的增加。CRC细胞存在高铁水平和高ROS水平,诱导发生铁死亡可能成为CRC新的治疗方法。本文综述了目前关于铁死亡机制的研究进展,介绍目前最新铁死亡诱导剂,包括小分子化合物以及纳米颗粒,为CRC开发新的治疗方案提供思路。

关键词：结直肠癌铁死亡小分子化合物纳米颗粒

Values of binary linear forms at prime arguments

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Frontiers of Mathematics in China 2015年第6期10卷 1449-1459页

作者： yuchao WANG Department of Mathematics Shanghai University Shanghai 200444 China

We investigate the exceptional set of real numbers not close to some value of a given binary linear form at prime arguments. Let λ1 and λ2 be positive real numbers such that λ1/λ2 is irrational and algebraic. For any （C, c） well-spaced sequence v and δ 〉 0, let E（v, X,δ ） denote the number of ν∈v with v ≤ X for which the inequality ｜λ1P1 ＋ λ2P2 - v｜〈 v-δ has no solution in primes P1,P2. It is shown that for any ε 〉 0, we have E（V, X, δ）〈〈 max（X3/5＋2δ＋ε, X1/3＋4/3δ＋ε）.

关键词： Circle method Diophantine inequality

Traffic prediction enabled dynamic access points switching for energy saving in dense networks

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Digital Communications and Networks 2023年第4期9卷 1023-1031页

作者： yuchao Zhu Shaowei Wang School of Electronic Science and Engineering Nanjing UniversityNanjing210000China

To meet the ever-increasing traffic demand and enhance the coverage of cellular networks,network densification is one of the crucial paradigms of 5G and beyond mobile networks,which can improve system capacity by deploying a large number of Access Points(APs)in the service ***,since the energy consumption of APs generally accounts for a substantial part of the communication system,how to deal with the consequent energy issue is a challenging task for a mobile network with densely deployed *** this paper,we propose an intelligent AP switching on/off scheme to reduce the system energy consumption with the prerequisite of guaranteeing the quality of service,where the signaling overhead is also taken into consideration to ensure the stability of the ***,based on historical traffic data,a long short-term memory method is introduced to predict the future traffic distribution,by which we can roughly determine when the AP switching operation should be triggered;second,we present an efficient three-step AP selection strategy to determine which of the APs would be switched on or off;third,an AP switching scheme with a threshold is proposed to adjust the switching frequency so as to improve the stability of the *** results indicate that our proposed traffic forecasting method performs well in practical scenarios,where the normalized root mean square error is within 10%.Furthermore,the achieved energy-saving is more than 28% on average with a reasonable outage probability and switching frequency for an area served by 40 APs in a commercial mobile network.

关键词： Access points switching on/off Energy-saving Green network Long short-term memory Traffic prediction

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苏北不同林龄杨树人工林碳储量时空分配格局

水土保持研究 2025年第1期32卷 243-248页

作者：顾宇晨张茜安宇超王国兵南京林业大学生态与环境学院南方现代林业协同创新中心

[目的]探讨不同林龄对苏北杨树人工林生产力形成及林分碳储量地上、地下空间分配格局的影响及机理，为提高杨树人工林生态系统碳汇功能以及为杨树人工林经营和管理等提供科学依据。[方法]基于江苏省宿迁市泗洪林场，选取10个不同林龄分... 详细信息

[目的]探讨不同林龄对苏北杨树人工林生产力形成及林分碳储量地上、地下空间分配格局的影响及机理，为提高杨树人工林生态系统碳汇功能以及为杨树人工林经营和管理等提供科学依据。[方法]基于江苏省宿迁市泗洪林场，选取10个不同林龄分别为2,5,6,7,8,10,14,16,17,26 a生，林分密度为6 m×6 m的杨树人工林作为试验调查样地。分析了杨树人工林乔木层、草本层及土壤层碳储量净积累随林龄的变化规律及杨树人工林不同层次碳储量变化与土壤理化性质的相关关系。[结果]（1）乔木层碳储量在林分发展过程中呈现快速净积累特征，拟合其年平均积累速率、连年积累速率两条曲线，表明杨树人工林最佳轮伐期为15～20 a;（2）土壤有机碳在林分发展过程中呈现出缓慢的净积累，林下草本层碳储量随林分发展呈降低趋势；（3）杨树人工林土壤层和乔木层碳储量与土壤中SOC,TN,NO-3-N,N/P呈显著正相关，与AP,C/N,pH呈负相关。[结论]在杨树人工林生长过程中施N肥以及在土壤固碳水平最佳时期15～20 a进行轮作，有助于林分碳储量增加。

关键词：碳储量杨树人工林不同林龄苏北地区

Constrained LQ Problem with a Random Jump and Application to Portfolio Selection

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Chinese Annals of Mathematics,Series B 2018年第5期39卷 829-848页

作者： yuchao DONG Department of Mathematics Fudan University

This paper deals with a constrained stochastic linear-quadratic（LQ for short）optimal control problem where the control is constrained in a closed cone. The state process is governed by a controlled SDE with random coefficients. Moreover, there is a random jump of the state process. In mathematical finance, the random jump often represents the default of a counter party. Thanks to the Ito-Tanaka formula, optimal control and optimal value can be obtained by solutions of a system of backward stochastic differential equations（BSDEs for short）. The solvability of the BSDEs is obtained by solving a recursive system of BSDEs driven by the Brownian motions. The author also applies the result to the mean variance portfolio selection problem in which the stock price can be affected by the default of a counterparty.

关键词： Backward stochastic Riccati equation Default time Mean-varianceproblem

On the saturation number for singular cubic surfaces

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Science China Mathematics 2023年第12期66卷 2803-2818页

作者： yuchao Wang Weili Yao Department of Mathematics Shanghai UniversityShanghai 200444China

We investigate the distribution of rational points on singular cubic surfaces,whose coordinates have few prime *** key tools used are universal torors,the circle method and results on linear equations in primes.

关键词： circle method universal torsors cubic surfaces prime

Decreasing ruminal methane production through enhancing the sulfate reduction pathway

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Animal Nutrition 2022年第2期9卷 320-326页

作者： yuchao Zhao Guangyong Zhao State Key Laboratory of Animal Nutrition College of Animal Science and TechnologyChina Agricultural University100193 BeijingChina

Methane(CH4)production from ruminants accounts for 16%of the global greenhouse gas emissions and represents 2%to 12%of feed *** CH_(4) production from ruminants is of great importance for sustainable development of the ruminant industry.H_(2) is the primary substrate for CH_(4) production in the processes of ruminal *** reducing bacteria are able to compete with methanogens for H_(2) in the rumen,and consequently inhibit the *** the ruminal sulfate reducing pathway is an important approach to mitigate CH_(4) emissions in *** review summarized the effects of sulfate and elemental S on ruminal methanogenesis,and clarified the related mechanisms through the impacts of sulfate and elemental S on major ruminal sulfate reducing *** the activities of the major ruminal sulfate reducing bacteria including Desulfovibrio,Desulfohalobium and sulfolobus through dietary sulfate addition,elemental S and dried distillers grains with solubles can effectively decrease the ruminal CH_(4) *** levels of dietary addition with different S sources for reducing the ruminal CH_(4) production,as well as maintaining the performance and health of ruminants,need to be investigated in the future.

关键词： Methane Rumen sulfur sulfate reduction pathway