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Evaluation of ICUs and weight of quality control indicators:an exploratory study based on chinese ICU quality data from 2.15 to 2.2.

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Frontiers of Medicine 2023年第4期17卷 675-684页

作者： Longxiang su Xudong Ma Sifa Gao Zhi Yin Yujie Chen Wenhu wang Huaiwu He Wei Du Yaoda Hu Dandan Ma Feng Zhang Wen {2. Xiaoyang Meng Guoqiang sun Lian Ma Huizhen Jiang Guangliang Shan Dawei Liu Xiang Zhou china-NCCQC Department of Critical Care Medicine State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalPeking Union Medical College and Chinese Academy of Medical SciencesBeijing 100730China Department of Medical Administration National Health Commission of the People’s Republic of ChinaBeijing 100044China Intensive Care Unit The People’s Hospital of ZizhongNeijiang 641000China Department of Epidemiology and Biostatistics Institute of Basic Medicine SciencesChinese Academy of Medical Sciences&School of Basic MedicinePeking Union Medical CollegeBeijing 100730China Information center State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China 不详

This study aimed to explore key quality control factors that affected the prognosis of intensive care unit(ICU)patients in chinese mainland over six years(2.15–2.2.).The data for this study were from 31 provincial and municipal hospitals(342. hospital ICUs)and included 2.10685 ICU patients,for a total of 2.607376 ICU hospitalization *** found that 15 initially established quality control indicators were good predictors of patient prognosis,including percentage of ICU patients out of all inpatients(%),percentage of ICU bed occupancy of total inpatient bed occupancy(%),percentage of all ICU inpatients with an APACHE II score≥15(%),three-hour(surviving sepsis campaign)SSC bundle compliance(%),six-hour SSC bundle compliance(%),rate of microbe detection before antibiotics(%),percentage of drug deep venous thrombosis(DVT)prophylaxis(%),percentage of unplanned endotracheal extubations(%),percentage of patients reintubated within 48 hours(%),unplanned transfers to the ICU(%),48-h ICU readmission rate(%),ventilator associated pneumonia(VAP)(per 1000 ventilator days),catheter related blood stream infection(CRBSI)(per 1000 catheter days),catheter-associated urinary tract infections(CAUTI)(per 1000 catheter days),in-hospital mortality(%).When exploratory factor analysis was applied,the 15 indicators were divided into 6 core elements that varied in weight regarding quality evaluation:nosocomial infection management(2..35%),compliance with the surviving Sepsis Campaign guidelines(17.97%),ICU resources(17.46%),airway management(15.53%),prevention of deep-vein thrombosis(14.07%),and severity of patient condition(13.61%).Based on the different weights of the core elements associated with the 15 indicators,we developed an integrated quality scoring system defined as F score=2..35%xnosocomial infection management+17.97%xcompliance with SSC guidelines+17.46%×ICU resources+15.53%×airway management+14.07%×DVT prevention+13.61%×severity of patient *** evidence-based quality

关键词： critical care medicine quality control evaluation exploratory factor analysis(EFA)model

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Climatic change features of fog and haze in winter over North china and Huang-Huai Area

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Science china Earth sciences 2015年第5期58卷 1370-1376页

作者： YIN ZhiCong wang huijun GUO WenLi Nansen-zhu international {2. center Institute of Atmospheric Physics Chinese Academy of Sciences beijing Meteorology Bureau Climate Change research center Chinese Academy of Sciences

This paper revealed the climatic change characteristics of fog and haze of different levels over North china and Huang-Huai area(NCHH).It was found that the haze-prone period has changed from winter into a whole year,and the haze days(HD)in winter have increased *** foggy days(FD)are half of *** are little difference on the number of days and trends of fog at various *** HD and FD show no obvious positive correlation until the *** has larger spatial scale,showing more in the south than in the *** occurs mainly around large cities with a discrete *** the background of weakened East Asian Winter Monsoon(EAWM)and sufficient particulate matter,the negative correlation between haze and wind speed is weakened,but the positive correlation between haze and moisture conditions(precipitation and humidity)is significantly *** recent years,small wind and variability appear ***,as the stable source and strong moisture absorption of the aerosol particles,the moisture condition becomes one key control factor in the haze,especially wet haze with less *** contrast,the FD presents a stable positive correlation with precipitation and relative humidity,but has no obvious negative correlation with wind speed.

关键词： haze fog visibility east asian winter monsoon weather conditions

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Widespread glacier advances across the Tian Shan during Marine Isotope Stage 3 not supported by climate-glaciation simulations

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Fundamental research 2023年第1期3卷 102-110页

作者： Qing Yan Lewis A.Owen Chuncheng Guo Zhongshi Zhang Jinzhe Zhang huijun wang Nansen-zhu international {2. Centre Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Key Laboratory of Meteorological Disaster/Collaborative Innovation center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and TechnologyNanjing 210044China Department of Marine Earthand Atmospheric ScienceNorth Carolina State UniversityRaleighNC 27695United States NORCE Norwegian research Centre Bjerknes Centre for Climate ResearchBergenNorway Department of atmospheric Science School of Environmental StudiesChina University of GeosciencesWuhan 430074China

Whether there were more extensive glaciations during the Marine Isotope Stage(MIS)3 relative to MIS 2.across the Tian Shan in Central Asia is intensely debated because of the uncertainty in chronological data and fully understanding the driving *** help resolve the ongoing debate,we assess the climate sensitivity of the glaciers and reconstruct the extent of glaciation during MIS 2.and 3 across the Tian Shan,using a glacier-resolving(2.0×2.0 m)ice sheet model asynchronously coupled with a global climate *** results demonstrate that the equilibrium-line altitude(ELA)over the Tian Shan decreases by∼180 m for every 1°C cooling under a modern precipitation regime,but precipitation reduction greatly lowers the sensitivity of the glaciers to temperature decrease(e.g.,the effect of 2.C cooling is broadly offset by a 50%decrease in precipitation).Under the modeled colder/drier-than-present climate,the model predicts an ELA depression(∆ELA)of∼75 m(162.m)over the Tian Shan during MIS 3 interstadials(stadials).The extent of MIS 3 glaciation is much smaller than that during MIS 2.i.e.,∆ELA=∼72. m).The more extensive glaciation during MIS 2.is largely attributed to the enhanced summer ***,through a site-to-site model-data comparison,we find that the closest match between the modeled glacier margin and the locations of the glacial deposits previously argued to be MIS 3 is generally achieved under MIS 2.climatic *** results suggest more extensive glacier advances over the Tian Shan during MIS 2.than MIS 3 on a regional scale,although MIS 3 glaciation may still occur in individual glacier *** pattern suggests general synchronicity with the timing of maximum Northern Hemisphere ice sheets during the last glacial,which should be further tested in a multimodel framework in the future.

关键词： Glacier modeling Glacier sensitivity MIS 3 MIS 2 Tian Shan Paleoclimate modeling

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Influence of Strong Tropical Volcanic Eruptions on Daily Temperature and Precipitation Extremes Across the Globe

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Journal of Meteorological research 2021年第3期35卷 428-443页

作者： Tao wang Jiapeng MIAO huijun wang Jianqi suN Climate Change research center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029 Collaborative Innovation center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science&TechnologyNanjing 210044 Nansen-zhu international {2. center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029 Key Laboratory of Meteorological Disaster Nanjing University of Information Science&TechnologyNanjing 210044

This study investigates the influences of strong tropical volcanic eruptions(SVEs) on daily temperature and precipitation extreme events using long-term simulations from the Hadley Centre Coupled Model version 3(HadCM3) and the Community Earth System Model version 1.1(CESM1). The results indicate that the occurrences of daily hot extremes and daily heavy precipitation extremes decrease over most parts of the world in the peak forcing years of SVEs. Due to the volcanic cooling effect, the average probability of daily hot extremes decreases by approximately 50% across the globe. The decrease in intensity is stronger for midlatitude land regions and tropical South *** contrast, daily cold extremes occur more frequently over most parts of continental regions. Globally, a cold extreme event expected once every 3 years under non-volcanic conditions can be expected every 1.5 years on average in the peak forcing years. Overall, the SVE-induced cooling effect plays a dominant role in regulating daily cold and hot extremes. Over high-latitude Eurasian regions, in contrast to other continental regions, the probability and intensity of daily cold extremes decrease due to an SVE-strengthened polar vortex and the associated temperature advection anomalies. With regard to daily heavy precipitation extremes, the probability and intensity both decrease over most monsoon areas. Further analysis suggests that the reduced probability and intensity of daily heavy precipitation extremes are mainly due to the SVE-induced global decrease in the water-holding capacity.

关键词： strong tropical volcanic eruption(SVE) daily extremes temperature precipitation

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Preface to the Special Issue on the"Forecast and Evaluation of Meteorological Disasters"(FEMD)

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Advances in atmospheric sciences 2017年第2期34卷 127-127页

作者： huijun wang Collaborative Innovation center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and Technology Nanjing 210044China Nansen-zhu international {2. Centre Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China

Meteorological disasters usually exert huge impacts on the development of both human society and the economy. According to statistics from the United Nations international Strategy for Disaster Reduction, the annual mean economic loss caused by meteorological disasters accounts for 3%-6% of the total amount of global GDP.{2. is a country that has been one of the most severely influenced by natural disasters.

关键词： Forecast and Evaluation of Meteorological Disasters Preface to the Special Issue on the FEMD

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地学领域科学数据处理与分析软件自主性分析

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农业大数据学报 2024年第2期6卷 230-240页

作者：王卷乐李凯段博文苏娜中国科学院地理科学与资源研究所资源与环境信息系统国家重点实验室北京100101 中国科学院大学北京100049 江苏省地理信息资源开发与利用协同创新中心南京210023 中国科学院科技战略咨询研究院北京100190

科学数据的重要性已得到广泛共识,随着科学数据的不断积累,其数据处理分析软件的能力水平将成为科学数据能否高效发挥作用的关键和瓶颈。地球科学领域研究涉及多尺度、多类型、多来源的数据,其数据处理与分析软件的需求极为强烈。本研... 详细信息

科学数据的重要性已得到广泛共识,随着科学数据的不断积累,其数据处理分析软件的能力水平将成为科学数据能否高效发挥作用的关键和瓶颈。地球科学领域研究涉及多尺度、多类型、多来源的数据,其数据处理与分析软件的需求极为强烈。本研究针对地球科学领域的特点,分析其主要数据处理和分析软件的现况,辨识我国的软件自主程度。调研分析涉及地理、海洋、地质、大气、生态、灾害、农业等16个专题,选取了177个主流软件/工具,重点获取其软件/工具名称、概况、主要功能、应用服务/典型案例、优缺点、对标产品等指标。分析发现地学科学数据处理与分析领域软件/工具完全开放(开源)的占三分之二,商业的、限制性的或开放程度不明确的占三分之一。主要软件/工具开发国家有美国、中国、加拿大、英国等以及一些国际组织。从专题分布看,主要体现在土地退化、人口社会经济、知识图谱、遥感处理等。自主保障风险较高的软件主要在空间化、大气、野火、冻土等专题。约三分之一的专业软件/工具可以直接应用到国家科学数据中心,且可与云平台结合。结合人工智能时代和“数据要素×”的发展,从五个方面提出加强我国自主科学数据处理软件/工具的开发应用建议。

关键词：地球科学科学数据软件/工具自主性国家科学数据中心

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Role of land-atmosphere coupling in persistent extreme climate events in eastern china in summer 2.2.

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atmospheric and Oceanic Science Letters 2024年第2期17卷 19-26页

作者： Yue Chen Aihui wang Nansen-zhu international {2. Centre Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Collaborative Innovation center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD) Nanjing University of Information Science&TechnologyNanjingChina

2.2.年暖季,中国东部地区遭受持续性高温,少雨和土壤干旱的复合极端事件.特征分析指出,在研究时段内,中国东部地区的气温,降水和土壤湿度呈现明显的季节内变化和南北差异。由1940-2.2.年的气候态可知,长江流域和东南地区的土壤含水充足... 详细信息

2.2.年暖季,中国东部地区遭受持续性高温,少雨和土壤干旱的复合极端事件.特征分析指出,在研究时段内,中国东部地区的气温,降水和土壤湿度呈现明显的季节内变化和南北差异。由1940-2.2.年的气候态可知,长江流域和东南地区的土壤含水充足,蒸散主要受限于陆面有效能量.然而,潜在机制研究指出,2.2.年土壤湿度对蒸散的限制作用在上述区域异常偏强,土壤湿度与气候要素之间的强反馈可能在2.2.年复合极端事件的演变和持续中发挥了关键作用。

关键词：复合极端事件陆气耦合土壤湿度干旱中国东部

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Validation and correction of sea surface salinity retrieval from SMAP

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Acta Oceanologica Sinica 2020年第3期39卷 148-158页

作者： Sisi Qin Hui wang Jiang zhu Liying Wan Yu Zhang Haoyun wang National Meteorological center Beijing 100081China Numerical Weather Prediction center of china Meteorological Administration Beijing 100081China Key Laboratory of research on Marine Hazards Forecasting National Marine Environmental Forecasting CenterBeijing 100081China international center for Climate and Environment {2. Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China University of the chinese academy of sciences Beijing 100049China

In this study, sea surface salinity(SSS) Level 3(L3) daily product derived from soil moisture active passive(SMAP)during the year 2.16, was validated and compared with SSS daily products derived from soil Moisture and ocean salinity(SMOS) and in-situ measurements. Generally, the root mean square error(RMSE) of the daily SSS products is larger along the coastal areas and at high latitudes and is smaller in the tropical regions and open oceans. Comparisons between the two types of daily satellite SSS product revealed that the RMSE was higher in the daily SMOS product than in the SMAP, whereas the bias of the daily SMOS was observed to be less than that of the SMAP when compared with Argo floats data. In addition, the latitude-dependent bias and RMSE of the SMAP SSS were found to be primarily influenced by the precipitation and the sea surface temperature(SST). Then, a regression analysis method which has adopted the precipitation and SST data was used to correct the larger bias of the daily SMAP product. It was confirmed that the corrected daily SMAP product could be used for assimilation in high-resolution forecast models, due to the fact that it was demonstrated to be unbiased and much closer to the in-situ measurements than the original uncorrected SMAP product.

关键词： sea surface salinity(SSS) soil moisture active passive(SMAP) soil moisture and ocean salinity(SMOS) validation correction

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Aging weakens Th17 cell pathogenicity and ameliorates experimental autoimmune uveitis in mice

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Protein & Cell 2022年第6期13卷 422-445页

作者： He Li Lei zhu Rong wang Lihui Xie Jie Ren Shuai Ma Weiqi Zhang Xiuxing Liu Zhaohao Huang Binyao Chen Zhaohuai Li Huyi Feng Guang-Hui Liu Si wang Jing Qu Wenru su State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-Sen UniversityGuangzhou 510060China State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Advanced Innovation center for Human Brain Protection National Clinical Research Center for Geriatric DisordersXuanwu Hospital Capital Medical UniversityBeijing 100053China CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of SciencesBeijing 100101China institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijing 100101China Aging Translational Medicine center International Center for Aging and CancerXuanwu HospitalCapital Medical UniversityBeijing 100053China china National center for Bioinformation Beijing 100101China beijing institute for Stem Cell and Regenerative Medicine Beijing 100101China Chongqing Renji Hospital University of Chinese Academy of SciencesChongqing 400062China

Aging-induced changes in the immune system are associated with a higher incidence of infection and vaccination *** nodes,which filter the lymph to identify and fight infections,play a central role in this ***,careful characterization of the impact of aging on lymph nodes and associated autoimmune diseases is *** combined single-cell RNA sequencing(scRNA-seq)with flow cytometry to delineate the immune cell atlas of cervical draining lymph nodes(CDLNs)of both young and old mice with or without experimental autoimmune uveitis(EAU).We found extensive and complicated changes in the cellular constituents of CDLNs during *** confronted with autoimmune challenges,old mice developed milder EAU compared to young *** this EAU process,we highlighted that the pathogenicity of T helper 17 cells(Th17)was dampened,as shown by reduced GM-CSF secretion in old *** mitigated secretion of GMCSF contributed to alleviation of IL-2. secretion by antigen-presenting cells(APCs)and may,in turn,weaken APCs’effects on facilitating the pathogenicity of Th17 ***,our study further unveiled that aging downregulated GM-CSF secretion through reducing both the transcript and protein levels of IL-2.R in Th17 cells from ***,aging altered immune cell responses,especially through toning down Th17 cells,counteracting EAU challenge in old mice.

关键词： aging experimental autoimmune uveitis Th17 cell APCs single-cell sequencing

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临近空间大气风场温度场卫星遥感技术研究综述

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红外与激光工程 2024年第7期53卷 57-77页

作者：何微微宿家瑞冯玉涛王后茂李昊天武魁军李发泉烟台大学物理与电子信息学院山东烟台264005 中国科学院西安光学精密机械研究所陕西西安710119 中国科学院国家空间科学中心北京100190 中国科学院精密测量科学与技术创新研究院湖北武汉430071

研究临近空间的风场和温度场对大气圈层之间的动量及能量传输、大气成分的输运以及大气环流的非线性突变有重要的科学意义,然而此区域的大气风温数据稀缺是国际亟待解决的难题之一。卫星遥感技术是获取大气风温信息的重要手段,然而受工... 详细信息

研究临近空间的风场和温度场对大气圈层之间的动量及能量传输、大气成分的输运以及大气环流的非线性突变有重要的科学意义,然而此区域的大气风温数据稀缺是国际亟待解决的难题之一。卫星遥感技术是获取大气风温信息的重要手段,然而受工程难度的限制,目前国际上针对临近空间风温遥感的卫星载荷十分有限。首先,概述了国际上具有代表性的大气风温卫星遥感载荷的发展现状。然后,系统性地综述了针对临近空间区域的近红外、长波红外和中波红外三类典型的风温遥感技术的研究进展;包括各观测目标源的光谱特性、载荷仪器的研制进展、以及风温探测能力;并讨论了各技术方案的优劣性。最后,对多种技术方案进行了对比汇总,为后续临近空间探测技术提供了参考和启示。展望未来临近空间星载风温遥感技术的发展趋势,着眼于风温遥感载荷的空间覆盖能力、时间连续性及探测精度、同时讨论载荷研制的工程难度,为临近空间风温遥感卫星研发和应用提供有效思路。

关键词：临近空间卫星遥感风温探测气辉辐射

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