检索结果-南通市图书馆

Increased long-distance and homo-trans interactions related to H3K27me3 in Arabidopsis hybrids

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2024年第2期66卷 208-227页

作者： Zhaoxu Gao Yanning su Le Chang Guanzhong jiao Yang Ou Mei Yang Chao Xu Pengtao Liu Zejia Wang Zewen Qi Wenwen Liu Linhua sun Guangming He Xing Wang Deng Hang He School of Advanced Agriculture Sciences and School of Life Sciences State Key Laboratory of Protein and Plant Gene ResearchPeking UniversityBeijing 100871China College of Grassland Science Beijing Forestry UniversityBeijing 100083China Peking University Institute of Advanced Agricultural Sciences Shandong Laboratory of Advanced Agricultural Sciences in WeifangWeifang 261325China

In plants,the genome structure of hybrids changes compared with their parents,but the effects of these changes in hybrids remain *** reciprocal crosses between Col×C24 and C24×Col in Arabidopsis using high-throughput chromosome conformation capture assay(Hi-C)analysis,we found that hybrid three-dimensional(3D)chromatin organization had more long-distance interactions relative to parents,and this was mainly located in promoter regions and enriched in genes with heterosis-related *** interactions between euchromatin and heterochromatin were increased,and the compartment strength decreased in *** compartment domain(CD)boundaries,the distal interactions were more in hybrids than their *** the hybrids of CURLY LEAF(clf)mutants clfCol×clfC24and clfC24×clfCol,the heterosis phenotype was damaged,and the long-distance interactions in hybrids were fewer than in their parents with lower ***-seq data revealed higher levels of H3K27me3 in the region adjacent to the CD boundary and the same interactional homo-trans sites in the wild-type(WT)hybrids,which may have led to more long-distance *** addition,the differentially expressed genes(DEGs)located in the boundaries of CDs and loop regions changed obviously in WT,and the functional enrichment for DEGs was different between WT and clf in the longdistance interactions and loop *** findings may therefore propose a new epigenetic explanation of heterosis in the Arabidopsis hybrids and provide new insights into crop breeding and yield increase.

关键词： 3D chromatin organization H3K27me3 homo-trans hybrids long-distanceinteractions

在线全文

学校读者我要写书评

暂无评论

“非和谐”设计形态与审美要素分析

包装工程 2020年第22期41卷 201-206页

作者：叶莉矫苏平中国矿业大学徐州221116

目的选取当代西方具有代表性的“非和谐”设计实践,从形式分析的角度出发,重点对视觉设计领域中的“非和谐”形态进行分类研究与归纳总结。方法在设计学和美学的视角下,对和谐与“非和谐”交互式的发展历程进行文脉梳理,归纳了在审美观... 详细信息

目的选取当代西方具有代表性的“非和谐”设计实践,从形式分析的角度出发,重点对视觉设计领域中的“非和谐”形态进行分类研究与归纳总结。方法在设计学和美学的视角下,对和谐与“非和谐”交互式的发展历程进行文脉梳理,归纳了在审美观念多元化的当代,视觉形式语言非常规表达下的几类常见形态,并深入分析了此类“非和谐”设计形态的特征和审美要素,详细解析“非和谐”作为非常态设计形式运用的背景、表象与审美意味,继续深化对此类设计试验的认识。结论“非和谐”形态本身复杂与模糊的特征,都使其具有不稳定性和争议性,但不可否认“非和谐”设计实践获得了丰富的视觉词汇,扩张了和谐自身的形式语言和种类,是对设计观念的意义深化,对和谐自身的必要补充。

关键词：非和谐形式语言设计实践审美要素

在线全文

学校读者我要写书评

暂无评论

冲击载荷作用下液压支架的力传递分析

煤炭学报 2015年第11期40卷 2522-2527页

作者：梁利闯田嘉劲郑辉焦素娟上海交通大学机械系统与振动国家重点实验室上海200240

为研究冲击载荷作用下液压支架的力传递特性,利用ADAMS仿真软件建立了液压支架的多体动力学模型。模型中将液压支架的立柱液压缸、平衡液压缸、顶梁、前连杆、后连杆以及掩护梁等效为弹性体,用预载荷模拟正常工作条件下的静载荷,用阶跃... 详细信息

为研究冲击载荷作用下液压支架的力传递特性,利用ADAMS仿真软件建立了液压支架的多体动力学模型。模型中将液压支架的立柱液压缸、平衡液压缸、顶梁、前连杆、后连杆以及掩护梁等效为弹性体,用预载荷模拟正常工作条件下的静载荷,用阶跃载荷模拟基本顶断裂或垮塌时对支架的冲击力。基于此数值仿真模型,计算分析了冲击载荷作用于顶梁不同位置时液压支架各铰接点的力传递系数和各铰接点力对冲击载荷作用位置的敏感度。结果表明:冲击载荷作用位置对液压支架各铰接点力传递特性的影响不同,各铰接点对冲击载荷作用位置的敏感度也不相同。这些计算结果对于液压支架的自适应控制和等强度设计具有重要意义。

关键词：液压支架动力学模型冲击响应力传递特性

A real-world study of the differences in Traditional Chinese Medicine diagnosis and treatment rules for coronavirus disease 2019 between Northern and Southern China

在线全文

学校读者我要写书评

暂无评论

Journal of Traditional Chinese Medicine 2024年第4期44卷 822-829页

作者： su Rui su Youzhu WANG Shuo FAN Jie LIU Qingquan LIU Mifeng Department of infectious diseases Capital Medical University Beijing Hospital of Traditional Chinese MedicineBeijing 100010China

OBJECTIVE:To explore the differences in Traditional Chinese Medicine(TCM)diagnosis and treatment rules for coronavirus disease 2019(COVID-19)between Northern and Southern China based on the real-world data from 982 COVID-19 ***:All consecutive cases of COVID-19 admitted to the TCM department of designated COVID-19 hospitals in eight provinces and cities were retrospectively *** were divided into a Northern and a Southern group according to the location of the admitting *** symptoms,syndrome elements,syndrome distribution and herbal treatments were *** core prescriptions were extracted using the multiscale backbone-based network comparison algorithm(msbNC).REsuLTS:The distribution of syndrome elements showed that dampness was common in Northern and Southern China,wind and heat were more often present in the South,while fire toxin and spleen deficiency were more often encountered in the *** distribution of syndromes showed that the South was dominated by heat dampness accumulating in the lung(55.69%),while the North was dominated by dampness-toxin stagnating in the lung(44.90%).The results of core prescription mining showed that dispelling dampness,dispersing wind,clearing heat and strengthening spleen were the common treatment methods in Northern and Southern *** mild cases,Jinyinhua(Flos Lonicerae)and Lianqiao(Fructus Forsythiae suspensae)were often used in the South to clear heat and relieve exterior symptoms,while Chaihu(Radix Bupleuri Chinensis)and Huangqin(Radix Scutellariae Baicalensis)were often used in the North to relieve muscles by expelling *** moderate cases,Chaihu(Radix Bupleuri Chinensis),Qinghao(Herba Artemisiae Annuae),and Shigao(Gypsum Fibrosum)were often used to clear heat of Tri-jiao Channel and stomach in the South,while Fuling(Poria),Chenpi(Pericarpium Citri Reticulatae),and Dangshen(Radix Codonopsis)were often used to invigorate spleen and remove dampness in the *** severe cases

关键词： COVID-19 medicine,Chinese traditional North-South difference core prescription syndrome retrospective studies

Ultra-Wideband Low-Noise Amplifier

在线全文

学校读者我要写书评

暂无评论

Ultra-Wideband Low-Noise Amplifier

Clinical significance of the detection of Rh blood group antigens and irregular antibodies in pregnant women with a second pregnancy

2010 International Conference on Test and Measurement (ICTM2010)

作者： Kaizhuo Lei jiao su Jintao Shang Quanshun Cui and Haibo Yang College of Marine Engineering Northwestern Polytechnical University Xi’an Shaanxi Province China 710072

Ultra-Wideband （UWB） Low-Noise Amplifier （LNA） is an essential part of the digital TV and UWB signal processor,but what makes it hard to design is the comprehensive consideration of bandwidth,noise and gain control performance.A new solution of high performance amplifier with low-noise,UWB and direct current （DC） is presented （Fig.1）,which is composed of a precision pre-amplifier with AD797,a stepped gain controller with VCA810 and a digital potentiometer,an eight-order Bessel low-pass filter with LC network,a zero-drift corrector with the digital compensation *** test results （Tab 1-3 ＆ Fig.6） show that the gain of amplifier can be adjusted from 0 to 80dB by step,the fluctuation of the pass band from DC to 10MHz is less than 0.87dB,stop-band attenuation reaches -42dB/2fc,the equivalent input noise voltage is less than 7.2μ*** design successfully solves some high challenging contradictions,such as ultra-wideband and low-noise,stop-band attenuation and pass-band fluctuation,precise gain control and DC zero-drift correction.

关键词： amplifier ultra-wideband low-noise gain control zero-drift correction

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Journal of Hainan Medical University 2022年第8期28卷 23-28页

作者： Xiao-Ling Fu Xing-Dan Zhao Ai-Han Weng su-jiao Li Xue-Yu Wang Kai-Nian Yang Department of Blood Transfusion Hainan Women and Children’s Medical CenterHaikou 570311China Linze County People's Hospital Zhangye 734200.China

Objective:To investigate the phenotype distribution of five antigens of Rh blood group system and the specificity of Rh blood group irregular antibodies in pregnant women with second *** analyze the relationship between Rh blood group antibody and hemolytic disease of the newborn(HDN)in second-child pregnant women,and to provide laboratory basis for the diagnosis and treatment of hemolytic disease of the newborn(Rh-HDN).Methods:500 pregnant women with second child were collected as the study group and 500 pregnant women with first pregnancy as the control group(all pregnant women underwent obstetric examination in the integrated obsteric clinic of our hospital from January 2020 to January 2021).To detectethe Rh blood group antigens(D,C,c,E,e)of the two groups of samples,screene the irregular antibodies,identify the specificity of irregular antibodies,determine the titer and record the hemolytic disease of the newborn of pregnant women with positive Rh blood group ***:There were 11 Rh phenotypes in the pregnant women with second child in the study group:CCDee(152cases,30.4%),CcDEe(136cases,27.2%)CcDee(84cases,16.8%),ccDEE(30cases,6%),ccDee(31cases,6.2%),CCDEe(14cases,2.8%),ccDEe(9cases,1.8%),cc dee(18cases,3.6%),CCDEE(2cases,0.4%),CcdEe(12cases,2.4%),Ccdee(6cases,1.2%),CCd ee(6cases,1.2%).A total of 42 cases(8.4%)in the pregnant women with second child were negative for *** were 10 Rh phenotypes in the pregnant women with first pregnancy in the control group:CCDee(144cases,28.8%),CcDEe(138cases,27.6%),CcDee(90cases,18%),ccDEE(42cases,8.4%),ccDee(28cases,5.6%),CCDEe(10cases,2%),ccDEe(8cases,1.6%),cc dee(19cases,3.8%),CCDEE(1cases,0.2%),CcdEe(11cases,2.2%),Ccdee(9cases,1.8%).A total of 39 cases(7.8%)in the pregnant women with first pregnancy were negative for *** the pregnant women with second child in the study group,the positive rate of irregular antibody screening was 4.0%(20/500),and the specificity of Rh blood group antibodies was foun

关键词： Rh blood group antigen Pregnant woman Irregular antibody detection HDN

2010-2012年宁波市乙型流行性感冒病毒血凝素及神经氨酸酶基因差异分析

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华预防医学杂志 2013年第12期47卷 1100-1104页

作者：胡逢蛟李永东焦素黎张姝宁波市疾病预防控制中心病毒研究所 315010

目的分析2010-2012年宁波市乙型流行性感冒（简称流感）病毒的流行状态及表面抗原基因血凝素（HA）和神经氨酸酶（NA）进化情况.方法收集宁波市2010-2012年流感样患者的咽拭子和含漱液标本3440份,进行流感病毒分离鉴定;同时采集2010... 详细信息

目的分析2010-2012年宁波市乙型流行性感冒（简称流感）病毒的流行状态及表面抗原基因血凝素（HA）和神经氨酸酶（NA）进化情况.方法收集宁波市2010-2012年流感样患者的咽拭子和含漱液标本3440份,进行流感病毒分离鉴定;同时采集2010年正常人群血清628份,进行抗体滴度测定.选择不同时期乙型流感分离株进行HA和NA基因序列测定,分析病毒表面抗原基因的进化方向与流行规律的关系.结果共计109份临床样本分离出乙型流感病毒,其中Victoria系102份（93.6％）,Yamagata系7份（6.4％）;在628份正常人群血清中,Victoria和Yamagata系乙型流感病毒抗体阳性率分别为321 （51.1％）和300 （47.8％）,差异无统计学意义（x2=1.405,P＞0.05）.进化分析显示,2010-2012年Victoria系HA基因均聚集在疫苗株Malaysia/2506/2004分支中,而NA基因则出现了不同方向的进化分支.Victoria系流行株与Brisbane/60/2008在HA基因中仅1～5个氨基酸位点的差异,而NA基因上有6～16个位点的差异.相比HA基因,Victoria系NA的进化速度更快.结论 2010-2012年宁波市Victoria系乙型流感的NA基因进化速度比HA基因快;综合HA与NA基因序列分析对观察流感病毒的基因变异更为灵敏可靠.

关键词：流感病毒属B型血凝素类神经氨酸酶基因突变

Plant regeneration in the new era:from molecular mechanisms to biotechnology applications

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第7期67卷 1338-1367页

作者： Chunli Chen Yuxin Hu Momoko Ikeuchi Yuling jiao Kalika Prasad Ying Hua su Jun Xiao Lin Xu Weibing Yang Zhong Zhao Wenkun Zhou Yun Zhou Jian Gao Jia-Wei Wang National Key Laboratory for Germplasm Innovation&Utilization of Horticultural Crops Hubei Hongshan LaboratoryHuazhong Agricultural UniversityWuhan 430070China College of Life Science and Technology Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Plant Molecular Physiology Institute of BotanyChinese Academy of Sciences(CAS)China National Botanical GardenBeijing 100093China Division of Biological Sciences Graduate School of Science and TechnologyNara Institute of Science and TechnologyNara 630-0192Japan State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871China Peking-Tsinghua Center for Life Sciences Center for Quantitative BiologyAcademy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Indian Institute of Science Education and Research Pune 411008IndiaThiruvananthapuram 695551India State Key Laboratory of Wheat Improvement College of Life SciencesShandong Agricultural UniversityTai’an 271018China Sino-German Joint Research Center on Agricultural Biology Shandong Agricultural UniversityTai’an 271018China Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental Biology(IGDB)CASBeijing 100101China CAS-JIC Centre of Excellence for Plant and Microbial Science(CEPAMS) IGDBCASBeijing 100101China National Key Laboratory of Plant Molecular Genetics CEMPSInstitute of Plant Physiology and Ecology(SIPPE)CASShanghai 200032China CEPAMS SIPPECASShanghai 200032China Hefei National Laboratory for Physical Sciences at the Microscale CEMPSSchool of Life SciencesDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230027China State Key Laboratory of Plant Environmental Resilience College of Biological SciencesChina Agricultural UniversityBeijing 100193China Department of Botany and Plant Pathology and Center for Plant Biology Purdue UniversityWest Lafayette 47907USA School of Life Science and Technology Shang

Plants or tissues can be regenerated through various *** animal regeneration,cell totipotency and pluripotency are the molecular basis of plant *** systematic studies on Arabidopsis thaliana gradually unravel the fundamental mechanisms and principles underlying plant ***,plant hormones,cell division,epigenetic remodeling,and transcription factors play crucial roles in reprogramming somatic cells and reestablishing meristematic *** research on basal non-vascular plants and monocot crops has revealed that plant regeneration differs among species,with various plant species using distinct mechanisms and displaying significant differences in regenerative *** multi-omics studies at the single-cell level,tracking plant regeneration processes in real-time,and deciphering the natural variation in regenerative capacity will ultimately help understand the essence of plant regeneration,improve crop regeneration efficiency,and contribute to future crop design.

关键词： apical meristem model species regeneration phytohormone plant cell reprogramming somatic embryogenesis

Mass-produced and uniformly luminescent photochromic fibers toward future interactive wearable displays

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第4期13卷 593-595页

作者： Yan Li Yikai su Department of Electronic Engineering Shanghai Jiao Tong University200240 ShanghaiChina

Enabling flexible fibers with light-emitting capabilities has the potential to revolutionize the design of smart wearable interactive devices.A recent publication in Light Science&Application,an interdisciplinary team of scientists led by ***-Qing Lu and *** Tao has realized a highly flexible,uniformly luminescent photochromic fiber based on a mass-produced thermal drawing *** overcomes the shortcomings of existing commercial lightdiffusing fibers,exhibiting outstanding one-dimensional linear illumination *** research team integrated controllable photochromic fibers into various wearable interaction interfaces,providing a novel approach and insights to enable human-computer interaction.

关键词： interaction fibers uniformly