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(Bio)electrochemistry for the environment,ready for ignition?

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Environmental Science and Ecotechnology 2024年第1期17卷 1-3页

作者： Xiaofei Wang Kun Guo Korneel Rabaey Antonin prévoteau Center for Microbial Ecology and Technology Ghent UniversityBelgium CAPTUREFrieda Saeysstraat 19000 GhentBelgium Department of Chemical Engineering Xi'an Jiaotong UniversityChina Department of Biotechnology Ghent UniversityBelgium CAPTUREFrieda Saeysstraat 19000 GhentBelgium

We are facing multiple environmental challenges and a degrading ecosystem due to ever-increasing anthropogenic activities and the release of unwanted chemicals into the *** pollutants remain in the environment due to a lack of an appropriate electron donor or *** processes can provide this need through the supply and uptake of electrons in a very versatile and environmentally compatible *** two decades,we know that bacteria can also perform the role of electrocatalysts,coupling electrons to complex *** the framework of the electrification of the world,electrochemistry stands up as one of the most relevant and rapidly growing vectors to make use of renewable energy sources to carry on useful,“chemical-free”*** such,a diversity of new concepts involving electrodes have been developed and proposed for environmental remediation,waste treatment,resource recovery(water,metals,nutrients,electric power),environmental sensing,and sustainable production of commodity chemicals.

关键词： versatile carry chemicals

The g-factor measurement as an ultimate test for nuclear chirality

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Frontiers of physics 2024年第3期19卷 1-10页

作者： Ernest Grodner Michał Kowalczyk Julian Srebrny Leszek próchniak Chrystian Droste Jan Kownacki Maciej Kisieliński Krzysztof Starosta Takeshi Koike National Centre for Nuclear Research 05-540ŚwierkPoland Heavy ion Laboratory University of WarsawPasteura 5a02-093 WarsawPoland Faculty of Physics University of WarsawPasteura 502-093 WarsawPoland Simon Fraser University 8888 University Drive BurnabyB.C.Canada V5A 1S6 Department of Physics Tohoku UniversitySendaiMiyagi 980-8577Japan

We present results of a series of experiments aimed at finding the most direct fingerprints of a phenomenon of nuclear chirality. These experiments brought a detailed knowledge of the so called partner bands in 132La, 128Cs and 126Cs including absolute values of E2 and M1 transition probabilities obtained through the DSA (Doppler Shift Attenuation) method. Considering the indirect character of observables such as energies and transition rates we proposed measurement of the g-factor of a chosen state as a direct, ultimate test of chirality. Our experiment on the bandhead of partner bands in 128Cs showed feasibility of this approach. Measured value of the g-factor which suggests non-chiral character of this state leads to another puzzle in the chirality studies — how the chirality emerges with increasing spin of levels along a partner band.

关键词： nuclear chirality electromagnetic transitions electromagnetic moments level lifetimes

Data-driven modeling on anisotropic mechanical behavior of brain tissue with internal pressure

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Defence Technology（防务技术） 2024年第3期33卷 55-65页

作者： Zhiyuan Tang Yu Wang Khalil i.Elkhodary Zefeng Yu Shan Tang Dan Peng State Key Laboratory of Structural Analysis Optimization and CAE Software for Industrial EquipmentDalian University of Technology116023DalianPR China The Department of Mechanical Engineering The American University in CairoNew Cairo11835Egypt Department of Neurology The Second Hospital of Dalian Medical UniversityDalian116023PR China

Brain tissue is one of the softest parts of the human body,composed of white matter and grey *** mechanical behavior of the brain tissue plays an essential role in regulating brain morphology and brain ***,traumatic brain injury(TBi)and various brain diseases are also greatly influenced by the brain's mechanical *** white matter or grey matter,brain tissue contains multiscale structures composed of neurons,glial cells,fibers,blood vessels,etc.,each with different mechanical *** such,brain tissue exhibits complex mechanical behavior,usually with strong nonlinearity,heterogeneity,and directional *** a constitutive law for multiscale brain tissue using traditional function-based approaches can be very ***,this paper proposes a data-driven approach to establish the desired mechanical model of brain *** focus on blood vessels with internal pressure embedded in a white or grey matter matrix material to demonstrate our *** matrix is described by an isotropic or anisotropic nonlinear elastic model.A representative unit cell(RUC)with blood vessels is built,which is used to generate the stress-strain data under different internal blood pressure and various proportional displacement loading *** generated stress-strain data is then used to train a mechanical law using artificial neural networks to predict the macroscopic mechanical response of brain tissue under different internal ***,the trained material model is implemented into finite element software to predict the mechanical behavior of a whole brain under intracranial pressure and distributed body *** with a direct numerical simulation that employs a reference material model,our proposed approach greatly reduces the computational cost and improves modeling *** predictions made by our trained model demonstrate sufficient ***,we find that the level of internal blood pressur

关键词： Data driven Constitutive law Anisotropy Brain tissue internal pressure

Design,simulation,and testing of a tunable MEMS multi-threshold inertial switch

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Microsystems & Nanoengineering 2024年第2期10卷 37-46页

作者： Qiu Xu Rodrigo T.Rocha Yousef Algoos Eric Feron Mohammad i.Younis Faculty of Electronic information Engineering Huaiyin Institute of TechnologyHuai’an223003PR China Computer Electrical and Mathematical Science and Engineering DivisionKing Abdullah University of Science and TechnologyThuwal23955-6900Saudi Arabia Piezoelectric Microsystem Technologies Silicon Austria LabsVillach9524Austria Physical Sciences and Engineering Division King Abdullah University of Science and TechnologyThuwal23955Saudi Arabia Mechanical Engineering Department State University of New YorkBinghamtonNY13902USA

This paper presents a tunable multi-threshold micro-electromechanical inertial switch with adjustable threshold *** demonstrated device combines the advantages of accelerometers in providing quantitative acceleration measurements and g-threshold switches in saving power when in the inactive state upon experiencing acceleration below the *** designed proof-of-concept device with two thresholds consists of a cantilever microbeam and two stationary electrodes placed at different positions in the sensing *** adjustable threshold capability and the effect of the shock duration on the threshold acceleration are analytically investigated using a nonlinear beam *** are shown for the relationships among the applied bias voltage,the duration of shock impact,and the tunable *** fabricated prototypes are tested using a shock-table *** analytical results agree with the experimental *** designed device concept is very promising for the classification of the shock and impact loads in transportation and healthcare applications.

关键词： tunable acceleration testing

Antibacterial HA-coatings on bioresorbable Mg alloy

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Journal of Magnesium and Alloys 2024年第5期12卷 1965-1985页

作者： K.V.Nadaraia D.V.Mashtalyar M.A.Piatkova A.i.Pleshkova i.M.imshinetskiy M.S.Gerasimenko E.A.Belov V.V.Kumeiko D.N.Kozyrev K.A.Fomenko V.V.Mostovaya B.R.Torpanov A.R.Biktimirov i.S.Osmushko S.L.Sinebryukhov S.V.Gnedenkov institute of Chemistry FEB RAS 159 Pr.100-letiya VladivostokaVladivostok 690022Russia Far Eastern Federal University 10 Ajax BayRussky IslandVladivostok 690922Russia A.V.Zhirmunsky National Scientific Center of Marine Biology FEB RAS 17 St.PalchevskogoVladivostok 690041Russia Regional Clinical Dermatovenerological Dispensary 18 V St.GamarnikaVladivostok 690033Russia NMiC“Treatment and Rehabilitation Center” 3 Ivankovskoe highwayMoscow 125367Russia

in this study,a calcium-phosphate coating was formed on a Mg-Mn-Ce alloy by the plasma electrolytic oxidation(PEO).The antibiotic vancomycin,widely used in the treatment of infections caused by Staphylococcus aureus(***),was impregnated into the *** with vancomycin showed high bactericidal activity against *** mechanical and electrochemical properties of the formed coatings were studied,as well as in vitro cytotoxicity tests and in vivo tests on mature male rats were *** to SEM,EDS,XRD and XPS data,coatings had a developed morphology and contained hydroxyapatite,which indicates high *** analysis of roughness of coatings without and with vancomycin did not reveal any differences,confirming the high roughness of the *** electrochemical tests,an increase in corrosion resistance by more than two times after the application of PEO coatings was *** to the results of an in vivo study,after 28 days of the implantation of samples with calcium phosphate PEO coating and vancomycin,no signs of inflammation were observed,while an inflammatory reaction developed in the area of implantation of bare alloy,followed by *** release tests from the coatings show a sharp decrease in the concentration of the released antibiotic on day 7 and then a gradual decrease until day *** the experiment,no significant deviations in the condition and behavior of the animals were observed;clinical tests did not reveal a systemic toxic reaction.

关键词： Bioactive coatings Biocompatibility Mg alloy Plasma electrolytic oxidation Hydroxyapatite Vancomycin

Across two phylogeographic breaks: Quaternary evolutionary history of a mountain aspen (Populus rotundifolia) in the Hengduan Mountains

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Plant Diversity 2024年第3期46卷 321-332页

作者： Jieshi Tang Xiaoyan Fan Richard i.Milne Heng Yang Wenjing Tao Xinran Zhang Mengyun Guo Jialiang Li Kangshan Mao Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education College of Life SciencesState Key Laboratory of Hydraulics and Mountain River EngineeringSichuan UniversityChengdu 610065PR China institute of Molecular Plant Sciences University of EdinburghEdinburgh EH93JHUK School of Ecology and Environment Tibet UniversityLhasa 850000PR China

Biogeographical barriers to gene flow are central to plant *** East Asia,plant distribution is greatly influenced by two phylogeographic breaks,the Mekong-Salween Divide and Tanaka-Kaiyong Line,however,few studies have investigated how these barriers affect the genetic diversity of species that are distributed across *** we used 14 microsatellite loci and four chloroplast DNA fragments to examine genetic diversity and distribution patterns of 49 populations of Populus rotundifolia,a species that spans both the Mekong-Salween Divide and the Tanaka-Kaiyong Line in southwestern *** and migration hypotheses were tested using coalescent-based *** historical gene flow was observed between the western and eastern groups of ***,but substantial flow occurred across both the Mekong-Salween Divide and Tanaka-Kaiyong Line,manifesting in clear admixture and high genetic diversity in the central ***-borne pollen and seeds may have facilitated the dispersal of *** following prevalent northwest winds in the *** also found that the Hengduan Mountains,where multiple genetic barriers were detected,acted on the whole as a barrier between the western and eastern groups of *** niche modeling suggested that *** has undergone range expansion since the last glacial maximum,and demographic reconstruction indicated an earlier population expansion around 600 *** phylogeographic pattern of *** reflects the interplay of biological traits,wind patterns,barriers,niche differentiation,and Quaternary climate *** study emphasizes the need for multiple lines of evidence in understanding the Quaternary evolution of plants in topographically complex areas.

关键词： Chloroplast DNA Microsatellite Phylogeographic break Populus rotundifolia Quaternary history Wind direction

impacts of interactions with low-mineralized water on permeability and pore behavior of carbonate reservoirs

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Energy Geoscience 2024年第4期5卷 278-290页

作者： Dmitriy A.Martyushev inna N.Ponomareva Vasiliy i.Chernykh Shadfar Davoodi Yousef Kazemzadeh Tianshou Ma Department of Oil and Gas Technologies Perm National Research Polytechnic UniversityPermRussia School of Earth Sciences&Engineering Tomsk Polytechnic UniversityLenin AvenueTomskRussia Enhanced Oil Recovery(EOR)Research Center IOR/EOR Research InstituteShiraz UniversityShirazIran State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengduSichuanPR China

Laboratory filtration experiments are employed to investigate effective well killing while minimizing its impacts on surrounding *** novelty of this experimental study lies in the prolonged exposure of rock samples to the killing fluid for seven days,corresponding to the average duration of well workovers in the oilfields in Perm Krai,*** findings indicate that critical factors influencing the interactions between rocks and the killing fluid include the chemical composition of the killing fluid,the mineralogical composition of the carbonate rocks,reservoir pressure and temperature,and the contact *** analyses using multi-scale X-ray computed tomography,field emission scanning electron microscopy,and X-ray diffraction were conducted on samples both before and after the well killing *** experiments were performed using real samples of cores,crude oil,and the killing *** results from this study indicate that low-mineralized water(practically fresh water)is a carbonate rock *** water causes the dissolution of rock components,the formation of new calcite crystals and amoeba-like secretions,and the migration of small particles(clay,quartz,and carbonates).The formation of deep channels was also *** assessment reveals that the change in the pH of the killing fluid indicates that the observed mineral reactions were caused by carbonate *** combined phenomena led to a decrease in the total number of voids in the core samples,which was 25%on average,predominantly among voids measuring between 45 and 70μm in *** change in the pore distribution in the bulk of the samples resulted in decreases in porosity of 1.8%and permeability of 67.0%in the studied core *** results from this study indicate the unsuitability of low-mineralized water as a well killing fluid in carbonate *** composition of the killing fluid should be optimized,for example,in terms of the ionic composition of water,

关键词： Fine particle Clay mineral Low-mineralized water Geochemical dissolution Carbonate reservoir

Dysfunction of the adhesion G protein-coupled receptor latrophilin 1(ADGRL1/LPHN1)increases the risk of obesity

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Signal Transduction and Targeted Therapy 2024年第5期9卷 2298-2311页

作者： Heba ZabriTorsten Schöneberg AndréNguyen Dietzsch Hadi Al-Hasani Joachim Altschmied Katharina Bottermann Jana Brendler Judith Haendeler Susanne Horn isabell Kaczmarek Antje Körner Kerstin Krause Kathrin Landgraf Diana Le Duc Laura Lehmann Stefan Lehr Stephanie Pick Albert Ricken Rene Schnorr Angela Schulz Martina Strnadová Akhil Velluva Heba Zabri Torsten Schöneberg Doreen Thor Simone prömel Rudolf Schönheimer institute of Biochemistry Medical FacultyLeipzig UniversityLeipzigGermany institute for Clinical Biochemistry and Pathobiochemistry Medical FacultyGerman Diabetes CenterLeibniz Center for Diabetes Research at Heinrich Heine University DüsseldorfDüsseldorfGermany German Center for Diabetes Research(DZD e.V.) Munich-NeuherbergGermany Cardiovascular Degeneration Clinical Chemistry and Laboratory DiagnosticsMedical FacultyUniversity Hospital and Heinrich Heine University DüsseldorfDüsseldorfGermany Cardiovascular Research institute(CARiD) Medical FacultyUniversity Hospital and Heinrich Heine University DüsseldorfDüsseldorfGermany institute of Pharmacology Medical FacultyUniversity Hospital and Heinrich Heine University DüsseldorfDüsseldorfGermany institute of Anatomy Medical FacultyLeipzig UniversityLeipzigGermany Center for Pediatric Research Hospital for Children and AdolescentsMedical FacultyLeipzig UniversityLeipzigGermany Helmholtz institute for Metabolic Obesity and Vascular Research(HI-MAG)of the Helmholtz Zentrum München at the University of Leipzig and University Hospital LeipzigLeipzigGermany Department of Endocrinology NephrologyRheumatologyLeipzig University Medical CenterLeipzigGermany institute of Human Genetics Leipzig University Medical CenterLeipzigGermany institute of Cell Biology Department of BiologyHeinrich Heine University DüsseldorfDüsseldorfGermany School of Medicine University of Global Health EquityKigaliRwanda

Obesity is one of the diseases with severe health consequences and rapidly increasing worldwide *** the complex network of food intake and energy balance regulation is an essential prerequisite for pharmacological intervention with obesity.G protein-coupled receptors(GPCRs)are among the main modulators of metabolism and energy ***,for instance,regulate appetite and satiety in certain hypothalamic neurons,as well as glucose and lipid metabolism and hormone secretion from *** in some GPCRs,such as the melanocortin receptor type 4(MC4R),have been associated with early-onset ***,we identified the adhesion GPCR latrophilin 1(ADGRL1/LPHN1)as a member of the regulating network governing food intake and the maintenance of energy *** of the highly conserved receptor in mice results in increased food consumption and severe obesity,accompanied by dysregulation of glucose ***,we identified a partially inactivating mutation in human ADGRL1/LPHN1 in a patient suffering from ***,we propose that LPHN1 dysfunction is a risk factor for obesity development.

关键词： obesity metabolism intake

Knock-out of BnHva22c reduces the susceptibility of Brassica napus to infection with the fungal pathogen Verticillium longisporum

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The Crop Journal 2024年第2期12卷 503-514页

作者： Wanzhi Ye Roxana Hossain Michael prbsting Abdallah Abdelmegid Mohamed Ali Lingyue Han Ying Miao Steffen Rietz Daguang Cai Dirk Schenke Department of Molecular Phytopathology and Biotechnology Institute of PhytopathologyChristian-Albrechts-University of KielKielGermany institut für Zuckerrübenforschung GöttingenGermany Plant Pathology Department Faculty of Agriculture and Natural ResourcesAswan UniversityAswanEgypt Fujian provincial Key Laboratory of Plant Functional Biology College of Life SciencesFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Hohenlieth-Hof NPZ Innovation GmbHHoltseeGermany

Verticillium longisporum(Vl43)is a soilborne hemibiotrophic fungal pathogen causing stem striping on oilseed rape(OSR)and severe yield *** for resistant varieties is the most promising approach to control this ***,we report the identification of Hva22c as a novel susceptibility factor and its potential for improving OSR ***22c is a member of the Hva22 gene family,originally described for barley(Hordeum vulgare).Several Hva22 members have been located at the endoplasmic ***22c is up-regulated in response to Vl43 in both Arabidopsis and *** demonstrate that knock-out of Hva22c in OSR by CRiSpr/Cas9 and its homolog in Arabidopsis by T-DNA insertion reduced plants’susceptibility to Vl43 infection and impaired the development of disease *** understand the underlying mechanism,we analysed transcriptomic data from infected and non-infected roots of hva22c knock-out and wild type *** identified a homozygous mutant with frame-shifts in all four BnHva22c loci displaying a vastly altered transcriptional landscape at 6 ***,a large set of genes was suppressed under mock conditions including genes related to the endomembrane *** the up-regulated genes we found several defense-related and phytohormone-responsive genes when comparing mutant to the wild *** results demonstrate that Hva22c is functionally required for a fully compatible plant-fungus *** loss of function reduces plant susceptibility,most likely due to endoplasmatic reticulum and Golgi dysfunction accompanied by additionally activated defense *** findings can help improve OSR resistance to *** infection.

关键词： Hva22c Susceptibility factor CRiSpr/Cas9 Brassica napus Arabidopsis Verticillium longisporum Resistance breeding