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Feeding behavior and hormoligosis associated with imidacloprid resistance in Asian citrus psyllid,Diaphorina citri

Insect Science 2024年第4期31卷 1211-1221页

作者： Xue Dong chen justin George Lauren M.Diepenbrock Hunter Gossett Guoping liu Jawwad A.Qureshi Lukasz L.Stelinski Entomology and Nematology Department University of FloridaCitrus Research and Education CenterLake AlfredFloridaUSA Southern Insect Management Research Unit USDA-ARSStonevilleMississippiUSA Entomology and Nematology Department University of FloridaSouthwest Florida Research and Education CenterImmokaleeFloridaUSA

Imidacloprid is a neonicotinoid insecticide used for managing the Asian citrus psyllid,Diaphorina citri Kuwayama,which serves as vector of phytopathogens causing citrus ***,development of resistance to neonicotinoids among populations of *** has coincided with occasional control failures in the *** objectives of this research were to(1)survey current levels of imidacloprid resistance in Florida citrus;(2)compare feeding behavior between imidacloprid-resistant and susceptible *** using electrical penetration graph recordings,and(3)investigate the possible amplification of insecticide hormoligosis associated with *** surveys confirmed that the susceptibility of *** populations to imidacloprid has decreased in commercial Florida citrus groves compared with a laboratory-susceptible *** 12 generations of selection,resistance to imidacloprid increased by 438 fold compared with the susceptible ***-susceptible *** feeding on citrus exhibited significantly more bouts associated with intercellular pathway(c),phloem penetration(D),phloem salivation(E1),and nonprobing(Np)activities than imidacloprid-resistant ***,there were no differences observed in the frequency or duration of phloem ingestion or xylem feeding between susceptible and resistant *** was no statistical difference in fecundity between resistant and susceptible ***,the fecundity of imidacloprid-susceptible female *** treated with a sublethal concentration of imidacloprid(Lc_(25))increased significantly compared with controls,while such hormoligosis was less pronounced among imidacloprid-resistant *** results suggest that imidacloprid-resistant psyllids may cease feeding sooner than susceptible counterparts following sublethal exposure to this insecticide,indicative of a behavioral resistance mechanism.

关键词： artificial selection electrical penetration graph feeding behavior hormoligosis insecticide resistance sublethal exposure

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Fu-Zheng-Yi-liu Formula inhibits the stem cells and metastasis of prostate cancer via tumor-associated macrophages/c-c motif chemokine ligand 5 pathway in tumor microenvironment

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chinese Journal of Natural Medicines 2024年第6期22卷 501-514页

作者： cHEN chiwei HUANG Renlun WANG Neng ZHENG Yifeng ZHOU Jianfu YANG Bowen WANG Xuan ZHANG Juping PAN Bo cHEN Zhiqiang WANG Shengqi WANG Zhiyu XIANG songtao The Research center of Integrative cancer Medicine Discipline of Integrated Chinese and Western Medicinethe Second Clinical College of Guangzhou University of Chinese MedicineGuangzhou 510000China The First clinical college of Guangzhou University of chinese Medicine Guangzhou 510000China Guangdong Provincial Key Laboratory of clinical Research on Traditional chinese Medicine Syndrome Guangdong Provincial Academy of Chinese Medical SciencesGuangdong Provincial Hospital of Chinese MedicineGuangzhou 510000China Guangdong-Hong Kong-Macao Joint Lab on chinese Medicine and Immune Disease Research Guangzhou University of Chinese MedicineGuangzhou 510000China The Research center for Integrative Medicine School of Basic Medical SciencesGuangzhou University of Chinese MedicineGuangzhou 510000China State Key Laboratory of Dampness Syndrome of chinese Medicine The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510000China

Prostate cancer(Pca)is the second most common malignancy among men *** Fu-Zheng-Yi-liu(FZYL)Formula has been widely utilized in the treatment of *** study investigates whether the FZYL Formula can inhibit Pca by tar-geting the TAMs/ccL5 *** conducted in vitro co-cultures and in vivo co-injections of Pca cells and TAMs to mimic their *** showed that the FZYL Formula significantly reduced the proliferation,colony formation,subpopulations of PcScs,and sphere-formation efficacy of Pca cells,even in the presence of TAM ***,the Formula markedly decreased the migration,invasion,and epithelial-mesenchymal transition(EMT)of Pca cells induced by *** FZYL Formula also reversed M2 phenotype polarization in TAMs and dose-dependently reduced their ccL5 expression and secretion,with minimal cytotoxicity *** studies confirmed that the TAMs/ccL5 axis is a critical target of the FZYL Formula,as the addition of exogen-ous ccL5 partially reversed the formula’s inhibitory effects on PcScs self-renewal in the co-culture ***,the Formula also significantly inhibited the growth of Pca xenografts,bone metastasis,and PcScs activity in vivo by targeting the TAMs/ccL5 ***,this study not only elucidates the immunomodulatory mechanism of the FZYL Formula in Pca therapy but also highlights the TAMs/ccL5 axis as a promising therapeutic target.

关键词： Traditional chinese medicine Tumor-associated macrophages Prostate cancer stem cells ccL5 Tumor microenvironment

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Four-wave mixing in 1.3 μm epitaxial quantum dot lasers directly grown on silicon

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Photonics Research 2022年第5期10卷 1264-1270页

作者： JIANAN DUAN BOZHANG DONG WENG W.cHOW HEMING HUANG SHIHAO DING songtao liu.justin c.norman JOHN E.BOWERS FREDEIc GRILLOT LTcI Telecom ParisInstitut Polytechnique de Pahs91120 PalaiseauFrance Sandia National Laboratories AlbuquerqueNew Mexico 87185USA Institute for Energy Efficiency University of California Santa BarbaraSanta BarbaraCalifornia 93106USA center for High Technology Materials University of New-MexicoAlbuquerqueNew Mexico 87106USA State Key Laboratory on Tunable Laser Technology School of Electronic and Information EngineeringHarbin Institute of TechnologyShenzhen 518055China Ayar Labs Santa ClaraCalifornia 95054USA Quintessent Inc.GoletaCalifornia 93117USA

This work compares the four-wave mixing(FWM)effect in epitaxial quantum dot(QD)lasers grown on silicon with quantum well(QW)lasers.A comparison of theory and experiment results shows that the measured FWM coefficient is in good agreement with theoretical *** gain in signal power is higher for p-doped QD lasers than for undoped lasers,despite the same FWM *** to the near-zero linewidth enhancement factor,QD lasers exhibit FWM coefficients and conversion efficiency that are more than one order of magnitude higher than those of QW ***,this leads to self-mode locking in QD *** findings are useful for developing on-chip sources for photonic integrated circuits on silicon.

关键词： lasers quantum mixing

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复合型抗盐剂对Nacl胁迫下小麦种子萌发和生长的影响

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干旱地区农业研究 2024年第2期42卷 199-209页

作者：刘晓晨王树凤寿松涛张建锋中国林业科学研究院亚热带林业研究所浙江杭州311400 南京林业大学江苏南京210037 杭州市富阳区乡村振兴服务中心浙江杭州311400

将KNO_(3)、cacl_(2)、DA-6、KH_(2) PO_(4)、FeSO_(4)·7H_(2) O、MgSO_(4)·7H_(2) O和蔗糖7种物质组合配制复合型抗盐剂,以‘济麦22’为研究材料,采用水培法,探讨了不同浓度(0.2%、0.4%和0.6%)盐(Nacl)胁迫下,施加不同浓度(10%、20%和30%)抗盐剂对种子萌发及后续幼苗生长的影响,并提出了适合小麦的抗盐剂配方。结果表明:(1)30%、20%、10%抗盐剂分别对0.2%、0.4%、0.6%Nacl胁迫下小麦种子萌发的促进效果最好,发芽率分别提高了6.4%、12.0%、26.5%。(2)0.6%Nacl胁迫下添加抗盐剂,根干质量显著增加了29.7%~35.9%;在抗盐剂作用下,光合速率分别提高了67.5%~90.0%(0.2%Nacl胁迫)、13.3%~51.5%(0.4%Nacl胁迫)和0.4%~25.5%(0.6%Nacl胁迫),且30%抗盐剂显著增强了0.2%Nacl胁迫下小麦的光合作用,增幅达90.0%。添加抗盐剂使小麦的光合色素含量升高,其中叶绿素a在0.2%和0.4%Nacl胁迫下分别升高了22.5%~39.0%和41.7%~43.2%,叶绿素b分别升高了22.1%~31.0%和14.7%~22.5%,类胡萝卜素分别升高了12.2%~28.6%和24.4%~32.3%。此外,其他各项生理指标也有相应改善。(3)主成分分析结果显示,盐胁迫下30%抗盐剂处理后小麦的得分均为最高,为最适浓度配比。

关键词：复合抗盐剂小麦盐胁迫种子萌发抗性生理

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PDR复杂度及手术预后全身影响因素分析

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中华实验眼科杂志 2024年第8期42卷 729-735页

作者：浦利军刘锦牟朝霞袁松涛谢平刘庆淮胡仔仲张家港市第一人民医院眼科张家港215600 南京医科大学第一附属医院眼科南京210029

目的评估增生性糖尿病视网膜病变(PDR)的复杂度及手术预后的影响因素。方法本研究为cONcEPT临床试验的历史性队列研究,纳入2017年6月至2018年1月于南京医科大学第一附属医院诊断为PDR且接受23G经睫状体扁平部三通道玻璃体切割术治疗的患... 详细信息

目的评估增生性糖尿病视网膜病变(PDR)的复杂度及手术预后的影响因素。方法本研究为cONcEPT临床试验的历史性队列研究,纳入2017年6月至2018年1月于南京医科大学第一附属医院诊断为PDR且接受23G经睫状体扁平部三通道玻璃体切割术治疗的患者97例97眼,所有患者术前接受0.5 mg康柏西普玻璃体腔注射。根据PDR复杂度评分分为>3分组和≤3分组,比较2个组间全身因素的差异;采用多因素Logistic回归分析评估性别、年龄、高血压病史、肾功能不全、糖尿病病程、糖化血红蛋白水平对PDR病变程度及手术预后的影响;根据年龄分为3分组患者年龄为46.5(36.0,51.8)岁,小于PDR复杂度≤3分组的54.0(45.5,61.5)岁,差异有统计学意义(Z=1.835,P=0.002)。Logistic回归分析显示,在预测PDR复杂度评分>3分的模型中,仅年龄因素有统计学意义(P=0.005),年龄每下降1岁,PDR复杂度>3分的发生风险增加7.4%(OR:0.929,95%cI:0.883~0.977);全身因素中,3分患者比例总体比较差异均有统计学意义(均P3分患者比例明显高于45~<60岁组和≥60岁组,差异均有统计学意义(均P<0.017)。<45岁组、45~<60岁组和≥60岁组术中出血和硅油填充患者比例总体比较差异均有统计学意义(均P<0.05),其中<45岁组术中出血和硅油填充患者比例明显高于45~<60岁组和≥60岁组,差异均有统计学意义(均P<0.017)。<45岁组术后1个月出现黄斑水肿比例明显高于45~<60岁组和≥60岁组,差异均有统计学意义(均P<0.05)。结论在全身因素中,年龄是PDR复杂度升高以及导致患者预后不佳的主要影响因素;与高龄组相比,低龄组患者术中并发症及术后早期黄斑水肿的比例较高。

关键词：糖尿病视网膜病变玻璃体切割术并发症年龄出血影响因素

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cr12MoV钢铸坯碳化物解析

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中国冶金 2024年第9期34卷 45-54页

作者：郑鹏刘松涛徐翔宇刘斌付建勋上海大学材料科学与工程学院先进凝固技术中心省部共建高品质特殊钢冶金与制备国家重点实验室鞍钢集团北京研究院有限公司

cr12MoV钢是应用最广泛的冷作模具钢，属于高铬高碳莱氏体钢，钢中碳化物的形态、数量、大小和分布对cr12MoV钢的性能有重要影响。采用金相显微镜、扫描电镜、夹杂物三维腐刻装置、X射线衍射仪和能谱分析仪对某厂生产的cr12MoV模铸坯中... 详细信息

cr12MoV钢是应用最广泛的冷作模具钢，属于高铬高碳莱氏体钢，钢中碳化物的形态、数量、大小和分布对cr12MoV钢的性能有重要影响。采用金相显微镜、扫描电镜、夹杂物三维腐刻装置、X射线衍射仪和能谱分析仪对某厂生产的cr12MoV模铸坯中碳化物类型、形态及分布情况进行解析，使用Thermo-calc 2020b计算cr12MoV冷作模具钢的相转变和碳化物析出行为。结果表明，cr12MoV冷作模具钢碳化物类型为富铬富铁的M7c3型碳化物和M23c6型碳化物，M7c3型碳化物所含主要元素为铬、铁、碳、钼，M23c6型碳化物所含主要元素为铁、铬、钼、碳。铸坯中碳化物形貌主要可以分为4类，颗粒状碳化物、块状碳化物、棒状碳化物、网状碳化物。颗粒状碳化物尺寸为2～5μm,块状碳化物尺寸为10～15μm,棒状碳化物尺寸为30～40μm,网状碳化物由颗粒状、块状、棒状碳化物聚集形成，其尺寸达80μm。从边部到芯部碳化物形态的演变规律为颗粒状→块状→棒状→网状，边部到芯部碳化物不均匀性逐渐增强，边部碳化物呈颗粒状弥散分布，1/4处碳化物呈长棒状，芯部碳化物偏聚成网状；铸坯从边部到芯部，碳化物的平均等效直径由边部的5.7μm增加到芯部的8.5μm,碳化物面积比例由边部的8.2%增长到芯部的9.5%,碳化物的密度由边部的2 961个/mm2下降到芯部的1 189个/mm2。通过解析cr12MoV钢铸坯中碳化物的类型、形态与分布，寻找碳化物在铸坯中的分布规律，为工厂调控钢中碳化物形态、优化钢的性能提供理论依据。

关键词： cr12MoV 冷作模具钢模铸坯碳化物三维腐刻

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Infrared image segmentation method based on 2D histogram shape modification and optimal objective function

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Journal of Systems Engineering and Electronics 2013年第3期24卷 528-536页

作者： songtao liu Donghua Gao Fuliang Yin Faculty of Electronic Information&Electrical Engineering Dalian University of Technology Department of Information&communication Engineering Dalian Naval Academy

In the methods of image thresholding segmentation, such methods based on two-dimensional （2D） histogram and optimal objective functions are important. However, when they are used for infrared image segmentation, they are weak in suppressing background noises and worse in segmenting targets with non-uniform gray level. The concept of 2D histogram shape modification is proposed, which is realized by target information prior restraint after enhancing target information using plateau histogram equalization. The formula of 2D minimum Renyi entropy is deduced for image segmentation, then the shape-modified 2D histogram is combined wfth four optimal objective functions （i.e., maximum between-class variance, maximum entropy, maximum correlation and minimum Renyi entropy） respectively for the appli- cation of infrared image segmentation. Simultaneously, F-measure is introduced to evaluate the segmentation effects objectively. The experimental results show that F-measure is an effective evaluation index for image segmentation since its value is fully consistent with the subjective evaluation, and after 2D histogram shape modification, the methods of optimal objective functions can overcome their original forms＇ deficiency and their segmentation effects are more or less improvements, where the best one is the maximum entropy method based on 2D histogram shape modification.

关键词： infrared image segmentation 2D histogram Otsu maximum entropy maximum correlation minimum Renyi entropy.

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Automatic detection of oceanic eddies in reanalyzed SST images and its application in the East china Sea

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Science china Earth Sciences 2015年第12期58卷 2249-2259页

作者： ZHANG chunHua LI HongLin liu songtao SHAO LianJun ZHAO Zhao liu HongWei No.107 Beiqing Road Haidian District Beijing 100094 China

Oceanic eddies may cause local sea surface temperature （SST）, height, and salinity anomalies in remote sensing （RS） images. Remote sensed SST imagery has proven to be an effective technique in oceanic eddy detection, because of its high temporal and spatial resolution. Various techniques have been used to identify eddies from SST images. However, mainly owing to the strong morphological variation of oceanic eddies, there is arguably no uniquely correct eddy detection method. A scheme of algorithm based on quasi-contour tracing and clustering of eddy detection from SST dataset is presented. The method does not impose fixed restrictions or limitations during the course of ＂suspected＂ eddy detection, and any eddy-like structures can be detected as ＂suspected＂ eddies. Then, ＂true＂ eddies can be identified based on the combination of intensity and spatial/temporal scale criteria. This approach has been applied to detect eddies in the East china Sea by using Operational SST ＆ Sea Ice Analysis （OSTIA） dataset. Experiments proved that oceanic eddies ranging in diameter from tens to hundreds of kilometers can be detected. Through investigation of the 2007-2011 OSTIA daily SST dataset from the Kuroshio region in the East china Sea, we found that the most active regions for oceanic eddies are those along the Kuroshio path, northeast of Taiwan Island, the Yangtze Estuary and the Ryukyu Islands. About 86% of the cyclonic eddies and 87% of the anticyclonic eddies have the size of 50-100 km in diameter. Only 25% of the anticyclonic eddy and 26% of the cyclonic eddy have the strength more than 0.4℃ in the sea surface layer.

关键词： oceanic eddy detection sea surface temperature (SST) quasi-contour tracing quasi-contour clustering

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Integrated dispersion compensated mode-locked quantum dot laser

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Photonics Research 2020年第9期8卷 1428-1434页

作者： ZEYU ZHANG justin cnorman songtao liu ADITYA MALIK AND JOHN EBOWERS Electrical and computer Engineering Department University of California Santa BarbaraSanta BarbaraCalifornia 93106USA Materials Department University of California Santa BarbaraSanta BarbaraCalifornia 93106USA Institute for Energy Efficiency University of CaliforniaSanta BarbaraCalifornia 93106USA

Quantum dot lasers are excellent on-chip light sources,offering high defect tolerance,low threshold,low temperature variation,and high feedback *** a monolithic integration technique combining epitaxial quantum dot lasers with passive waveguides has not been demonstrated and is needed for complex photonic integrated *** present here,for the first time to our knowledge,a monolithc offset quantum dot integration platform that permits formation of a laser cavity utilizing both the robust quantum dot active region and the versatility of passive GaAs waveguide *** platform is substrate agnostic and therefore compatible with the quantum dot lasers directly grown on *** an illustration of the potential of this platform,we designed and fabricated a 20 GHz mode-locked laser with a dispersion-engineered on-chip waveguide *** to the dispersion compensation effect of the waveguide mirror,the pulse width of the mode-locked laser is reduced by a factor of 2.8.

关键词： waveguide passive quantum

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ce&F multifunctional modification improves the electrochemical performance of LicoO_(2)at 4.60 V

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Journal of Energy chemistry 2023年第10期85卷 324-334,I0010页

作者： Jiangli Feng chenhui Wang Hailin Lei songtao liu Jing liu You Han Jinli Zhang Wei Li School of chemical Engineering and Technology Tianjin UniversityTianjin 300072China Haihe Laboratory of Sustainable chemical Transformations Tianjin 300192China

Lithium cobalt oxide(LicoO_(2))is proverbially employed as cathode materials of lithium-ion batteries attributed to the high theoretical capacity,and currently,it is developing towards higher cut-off voltages in the pursuit of higher energy ***,it suffers from serious structural degradation and surface side reactions,in particular,at the voltage above 4.60 V,leading to rapid decay of the battery *** into account the desirable oxygen buffering property and the fast ion mobility characteristic of cerium oxide fluoride,in this work,we prepared ce&F co-modified LicoO_(2)by using the precursors of ce(NO_(3))_(3)·6H_(2)O and NH_(4)F,and evaluated the electrochemical performance under voltages exceeding 4.60 *** results indicated that the modified samples have multiphase heterostructure of surface ceO_(2-x)and unique ce-O-F solid solution *** 3.0–4.60 V and 25℃,the preferred sample LcO-0.5ce-0.3F has a high initial discharge specific capacity of 221.9 mA h g^(-1)at 0.1 c,with the retention of 80.3%and 89.6%after 300 cycles at 1 and 5 c,comparing with the pristine LcO(56.4%and 22.6%).And at 3.0–4.65 V,its retention is 64.0%after 300 cycles at 1 c,versus 8.5%of the pristine *** structural characterizations and DFT calculations,it suggests that ce^(4+)&F^(-)co-doping suppresses the H3 to H1/3 irreversible phase transition,stabilizes the lattice structure,and reduces the redox activity of the lattice oxygen by modulating the co 3d–O 2p energy band,consequently improving the electrochemical performance of LicoO_(2)at high voltages.

关键词： LicoO_(2) High-voltage electrochemical performance ce^(4+)&F^(-)co-doping Multiphase heterostructure DFT calculation

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