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Statistical distribution of nonlinear random wave height in shallow water

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Science china Earth Sciences 2010年第12期53卷 267-273页

作者： hou {{1.,DUAN YongLiang{2.CHEN GengXin{2.qi Peng1.song guiting1.& SI GuangCheng{1.1.institute of oceanology,Chinese Academy of Sciences,qingdao 2.6071.china 2.Graduate University of Chinese Academy of Sciences,Beijing 1.0049,china institute of {1. Chinese Academy of Sciences Qingdao China Graduate University of Chinese Academy of Sciences Beijing China

Here we present a statistical model of random wave,using Stokes wave theory of water wave dynamics,as well as a new nonlinear probability distribution function of wave height in shallow *** is more physically logical to use the wave steepness of shallow water and the factor of shallow water as the parameters in the wave height *** results indicate that the two parameters not only could be parameters of the distribution function of wave height but also could reflect the degree of wave height distribution deviation from the Rayleigh *** new wave height distribution overcomes the problem of Rayleigh distribution that the prediction of big wave is overestimated and the general wave is *** prediction of small probability wave height value of new distribution is also smaller than that of Rayleigh *** effect of wave steepness in shallow water is similar to that in deep water;but the factor of shallow water lowers the wave height distribution of the general wave with the reduced factor of wave *** also makes the wave height distribution of shallow water more *** results indicate that the new distribution fits the in situ measurements much better than other distributions.

关键词： wave height distribution nonlinearity the wave steepness of shallow water the factor of shallow water

Structural Features and Molecular Evolution of Bowman-Birk Protease Inhibitors and Their Potential Application

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Acta Biochimica et Biophysica Sinica 2005年第5期37卷 283-292页

作者： Rui-Feng qi~(1.2. Zhan-Wu {{2.~{2.Cheng-Wu CHI~(2.3). {2.College of Life Science, Northwest Normal University, Lanzhou 730070,{2.: 2.institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 2.003{2.{2. 3 institute of Protein Research, Tongji University, Shanghai 2.0092.{2. College of Life Science Northwest Normal UniversityLanzhou 730070 China institute of Biochemistry and Cell Biology Chinese Academy of SciencesShanghai 200031 China institute of Protein Research Tongji UniversityShanghai 200092 China

The Bowman-Birk inhibitors(BBIs)are well-studied serine protease inhibitors that areabundant in dicotyledonous and monocotyledonous *** from dicots usually have a molecular weightof 8k and are double-headed with two reactive sites,whereas those from monocots can be divided into twoclasses,one approximately 8 kDa in size with one reactive site(another reactive site was lost)and the otherapproximately 1. kDa in size with two reactive *** reactive site is located at unique exposed surfacesformed by a disulfide-linked β-sheet loop that is highly conserved,rigid and mostly composed of *** structural features and molecular evolution of inhibitors are described,focusing on the conserveddisulfide *** sunflower trypsin inhibitor-1.SFTI-1.,with 1. amino acid residues,is a recentlydiscovered bicyclic inhibitor,and is the most small and potent naturally occurring Bowman-Birk ***,BBIs have become a hot topic because of their potential *** are now used fordefense against pathogens and insects in transgenic plants,which has advantages over using toxic andpolluting *** could also be applied in the prevention of cancer,Dengue fever,and inflammatoryand allergic disorders,because of their inhibitory activity with respect to the serine proteases that play apivotal role in the development and pathogenesis of these *** canonical nine-residue loop of BBIs/STFI-1.provides an ideal template for drug design of specific inhibitors to target their respective proteases.

关键词： Bowman-Birk protease inhibitor sunflower trypsin inhibitor-1.SFTI-1. molecular evolution drug design

稳定同位素标记-高效液相色谱-串联质谱法测定动物源性食品中1.种利尿剂

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化学研究与应用 2024年第8期36卷 1941-1949页

作者：吴恋戴琴姚静唐柏杨廖梅杨小琪石培育陈世奇宋娟成都市食品检验研究院四川成都611130 国家市场监管重点实验室(营养与健康化学计量及应用) 北京100029 国家市场监管重点实验室(调味品监管技术) 重庆401102

本研究建立了稳定同位素标记-高效液相色谱串联质谱法测定动物源性食品中1.种利尿剂的方法。试样经5%甲酸乙腈提取,通过式固相萃取柱净化,采用液相色谱-质谱/质谱仪测定,同位素内标法定量。1.种利尿剂在各自浓度范围内线性关系良好,平... 详细信息

本研究建立了稳定同位素标记-高效液相色谱串联质谱法测定动物源性食品中12.利尿剂的方法。试样经5%甲酸乙腈提取,通过式固相萃取柱净化,采用液相色谱-质谱/质谱仪测定,同位素内标法定量。12.利尿剂在各自浓度范围内线性关系良好,平均回收率介于71.3%~104.7%,相对标准偏差介于1.2.~1.1}(n=6)。该方法具有灵敏度高、准确性好、操作简单、检测效率高等特点,能够满足多种动物源性食品中12.利尿剂的检测需求。

关键词：高效液相色谱-串联质谱动物源性食品利尿剂稳定同位素标记

Ⅲ期Kümmell病后柱截骨长节段椎弓钉固定

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中国矫形外科杂志 2024年第18期32卷 1708-1711页

作者：梁晓松张伟李大伟任帅孙其志中国融通医疗集团泰安八十八医院脊柱外科山东泰安271000

[目的]探讨后柱截骨术(posterior column osteotomy,PCO)和长节段椎弓根钉固定治疗Ⅲ期Kümmell病的疗效。[方法]回顾性分析2.1.年1.月—2.2.年1.月采用PCO截骨和长节段椎弓钉固定治疗Ⅲ期Kümmell病的1.例患者的临床资料。评估临床和... 详细信息

[目的]探讨后柱截骨术(posterior column osteotomy,PCO)和长节段椎弓根钉固定治疗Ⅲ期Kümmell病的疗效。[方法]回顾性分析2.1.年1.月—2.2.年1.月采用PCO截骨和长节段椎弓钉固定治疗Ⅲ期Kümmell病的1.例患者的临床资料。评估临床和影像结果。[结果]1.例患者均顺利手术,无死亡,无神经损伤加重等严重并发症,手术时间(1.3.6±37.3)min,术中出血量(335.2.67.8)ml,切口长度(2..6±3.2.cm。其中,2.患者出现谵妄,1.患者术后出现脑脊液漏,经相应处理,均无不良后果。随着术前、术后3个月及术后1.个月的时间推移,VAS评分[(8.7±1.2.,(2.{{1.),(1.9±0.8),P1.、ODI评分[(75.7±5.5),(2..7±4.8),(2..4±3.6),P1.和ASIA神经功能评级[C/D/E,(2.1./0),(1.5/6),(1.5/6),P1.均显著改善。影像方面,随时间推移,局部后凸Cobb角[(35.7±5.5)°,(7.1.3.9)°,(7.1.3.5)°,P1.和椎体前缘高度[(1..5±1.3)mm,(2..8±1.2.mm,(2..7±1.3)mm,P1.均有显著改善。[结论]PCO截骨长节段椎弓根钉固定治疗Ⅲ期Kümmell病是一种有效的手术方式。

关键词：骨质疏松症 Kümmell病后柱截骨长节段椎弓钉固定

Effect of increasing Arctic river runoff on the Atlantic meridional overturning circulation:a model study

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Acta Oceanologica Sinica 2017年第8期36卷 59-65页

作者： SHU qi qiAO Fangli {2. Zhenya XIAO Bin The First institute of Oceanography State Oceanic AdministrationQingdao 266061China Laboratory for Regional Oceanography and Numerical Modeling Qingdao National Laboratory for Marine Science and TechnologyQingdao 266237China Key Laboratory of Marine Science and Numerical Modeling State Oceanic AdministrationQingdao 266061China

An increasing amount of freshwater has been observed to enter the Arctic Ocean from the six largest Eurasian rivers over the past several decades. The increasing trend is projected to continue in the twenty-first century according to Coupled Model Intercomparison Project Phase 5 （CMIP5） coupled models. The present study found that water flux from rivers to the Arctic Ocean at the end of the century will be 1.4 times that in 1.50 according to CMIP5 projection results under Representative Concentration Pathway 8.5. The effect of increasing Arctic river runoff on the Atlantic meridional overturning circulation （AMOC） was investigated using an ocean-ice coupled model. Results obtained from two numerical experiments show that 1.0, 1.0 and 2.0 years after the start of an increase in the Arctic river runoff at a rate of 0.2.%/a, the AMOC will weaken by 0.6 （3%）, 1.2.（7%） and 1.8 （1.%） Sv. AMOC weakening is mainly caused by freshwater transported from increasing Arctic river runoff inhibiting the formation of North Atlantic Deep Water （NADW）. As the AMOC weakens, the deep seawater age will become older throug{1.t the Atlantic Basin owing to the increasing of Arctic runoff.

关键词： climate change Arctic river runoff Atlantic meridional overturning circulation

Highly Efficient Heavy-Metal-Ion Removal from Shellfish Processing Liquid with Low Protein and Polysaccharide Loss by Hybrid Mesoporous Silica Diol-APDC-SBA1.

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Journal of Ocean University of china 2023年第1期22卷 221-228页

作者： qi Yanxia song Yang LIU Chang qi Shizhe WANG Haibo CAO Jijuan ZHAO qiancheng College of Food Science and Engineering Dalian Ocean UniversityDalian 116023China Liaoning Provincial Aquatic Products Analyzing Testing and Processing Technology Scientific Service CenterDalian 116023China Key Laboratory of Biotechnology and Bioresources Utilization of Ministry of Education Dalian Minzu UniversityDalian 116600China Collaborative Innovation Center of Seafood Deep Processing Dalian Polytechnic UniversityDalian 116034China Dalian Key Laboratory of Marine Bioactive Substances Development and High Value Utilization Dalian 116034China

Heavy metal ions in shellfish products are harmful to human health,and their removal with low nutrient loss remains ***,a new type of mesoporous silica(SBA1.),modified internally with ammonium pyrrolidine dithiocarbamate(APDC)and externally with alkyl-diol groups,which was named as Diol-APDC-SBA1.,was successfully developed and characterized by powder X-ray diffraction patterns,nitrogen adsorption,and Fourier transform infrared *** solutions with lead,chromium,cadmium,and copper were used to investigate the adsorption capacity of ***-APDC-SBA1. was adopted to remove heavy metals from cooking liquids of clams(Ruditapes philippinarum),hydrolysate liquids of oysters(Ostrea gigas Thunberg),and polysaccharide solution from the cooking liquid of *** efficiencies of removing heavy metal ions and the loss rates of proteins and polysaccharides were *** results showed that the adsorption capacities of Diol-APDCSBA1. for Pb,Cr,Cd,and Cu in standard heavy-metal solutions were 1.1.4,1.6.{1..6,and 60.2.gg^(−1.,*** removal efficiency of Diol-APDC-SBA1. for Pb in the three shellfish processing liquids ranged from 60.5%to 99.6%.The Cr removal efficiency was above 99.9%in the oyster hydrolysate ***,the percentages of polysaccharide loss were 5.5%and 3.7%in the cooking liquid of clam and polysaccharide solution,respectively,and the protein loss was {1.in the oyster hydrolysate ***,the Diol-APDC-SBA1. material exhibits a great potential application in the removal of heavy metals from shellfish processing liquids with low losses of proteins and polysaccharides.

关键词： heavy-metal removal modified mesoporous silica shellfish processing liquid protein polysaccharide

Phycocyanin attenuates X-ray-induced pulmonary inflammation via the TLR2.MyD88-NF-κB signaling pathway

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Journal of oceanology and Limnology 2019年第5期37卷 1678-1685页

作者： LIU qi LI Wenjun LU Lina LIU Bin DU Zhenning qiN {2. Yantai institute of Coastal Zone Research Chinese Academy of SciencesYantai 264003China School of Pharmacy Yantai UniversityYantai 264005China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China

Phycocyanin (PC), a natural algal protein, is reported for having anti-oxidant and antiinfl ammatory properties. We investigated its ability to attenuate lung infl ammation in mice subjected to X-ray radiation. Male C57BL/6 mice were assigned to the control, total body irradiation, PC pretreatment, and PC treatment groups. Mice in the PC pretreatment group were gavaged with 2.0 mg/kg PC for 7 consecutive days before irradiation, and those in the PC treatment group were gavaged with 2.0 mg/kg PC for 7 consecutive days after irradiation. Lungs were collected on Day 7 after irradiation exposure. Hematoxylin and eosin staining of mouse lung sections showed considerable infl ammation damage 7 days after irradiation compared with the control lung but a reduction in pathological injury in the PC treatment group. Pretreatment or treatment with PC signifi cantly decreased levels of interleukin-6 and tumor necrosis factor-α in the lung, and also increased the relative mRNA expression of superoxide dismutase and glutathione. In vivo, PC signifi cantly reduced the expression of Toll-like receptor TLR2. myeloid diff erentiation primary response Myd88, and nuclear factor NF-κB, at both the transcriptional and translation level. Taken together, these data indicated that PC attenuated lung infl ammatory damage induced by radiation by blocking the TLR2. MyD88-NF-κB signaling pathway. Therefore, PC could be a protective agent against radiation-induced infl ammatory damage in normal tissues.

关键词： phycocyanin infl ammatory TLR2.MyD88-NF-κB signaling pathway

New Neuraminidase Inhibitory Alkaloids from the Mangrove Soil-Derived Fungus Arthrinium *** 41.05

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中国海洋大学学报:英文版 2023年第5期22卷 1446-1451页

作者： HU Yiwei ZHAO Kai ZHU Junheng qi Xin CHEN Weihao song Yingying PANG Xiaoyan LIU Yonghong WANG Junfeng CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology Guangdong Key Laboratory of Marine Materia MedicaInnovation Academy of South China Sea Ecology and Environmental EngineeringSouth China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 510301China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 511458China University of Chinese Academy of Sciences Beijing 100049China

New alkaloid,(E)-2.(hydroxyimino)-4-methylpentanamide(1.and a new cyclopentano[b]pyridine,4-hydroxy-7-methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-one(2.,together with ten known compounds(3–1.)were isolated from the mangrove soil-derived fungus Arthrinium *** *** spectroscopic analysis and X-Ray crystallographic analysis were used to elucidate the structure of(E)-2.(hydroxyimino)-4-methylpentanamide(1.,including its absolute *** the isolated compounds(1.1.)were evaluated for their antimicrobial and enzyme inhibitory activities against acetylcholinesterase(ACh E),neuraminidase(NAs),and phosphatidylinositol 3-kinase(PI3K).Among them,compounds 1.and 3 exhibited strong neuraminidase inhibitory activity with IC_(50)values of 1..04,1.92.mol L^(-1.(IC_(50)2.μmol L^(-1.for oseltamivir acid),while compounds 5,6,8,and 1.showed moderate neuraminidase inhibitory activity,and compounds 6–1. displayed weak enzyme inhibitory activities against PI3K.

关键词： Arthrinium alkaloid pyridine neuraminidase acetylcholinesterase

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正交设计法优化减振橡胶材料的配方

橡胶科技 2024年第10期22卷 565-569页

作者：田安伟庞松杨灵斌岳伟平何琪李恒荣建新赵氏科技股份有限公司浙江宁海315000 宁波大学博士后流动站浙江宁波315211

采用正交设计法研究硫黄用量、促进剂DPTT用量和填料体系对减振橡胶材料性能的影响。结果表明:填料体系对胶料压缩永久变形的影响较大;硫黄用量则是对胶料的拉伸强度、拉断伸长率和老化后拉断伸长率变化率影响最大的因素。满足兼具低压... 详细信息

采用正交设计法研究硫黄用量、促进剂DPTT用量和填料体系对减振橡胶材料性能的影响。结果表明:填料体系对胶料压缩永久变形的影响较大;硫黄用量则是对胶料的拉伸强度、拉断伸长率和老化后拉断伸长率变化率影响最大的因素。满足兼具低压缩永久变形、优异的物理性能和耐老化性能的减振橡胶材料配方优化方案如下:硫黄用量为1.2.,促进剂DPTT用量为0.3份,填料体系中炭黑N32.、炭黑N774和白炭黑用量分别为2.,3{1.份。

关键词：减振橡胶材料正交试验硫黄促进剂填料体系压缩永久变形