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Study on Age and Education Level and Their Relationship with Fall-Related Injuries in Shanghai, China

Biomedical and Environmental Sciences 2013年第2期26卷 79-86页

作者： LI Yan Hong song gui xiang YU Yan ZHOU De Ding ZHANG Hong Wei Department of Injury Prevention and Control Shanghai Municipal Center for Disease Control&Prevention Department of Vital Statistics Shanghai Municipal Center for Disease Control&Prevention Department of Epidemiology Second Military Medical University

Objective To study age and educational level and their relationship with fall-related injuries in Shanghai and to analyze the relevant costs. Methods Multistage cluster sampling was used for the selection of participants and standardized questionnaires were used for the information collection in 2006. Information on cases and deaths caused by fall-related injuries were obtained from 494 hospitals as well as from the mortality registry systems from 2001 till 2010. Results Of 45 857 participates, 674 suffered from fall-related injuries with the largest proportion among all injuries. The fall-related mortality increased from 10.63 per 100 000 in 2001 to 14.11 per 100 000 in 2010. The under-five mortality rate was the highest among children aged 0-14 years. Mortality increased dramatically among those aged 55 or above for the female and aged 60 or older for the male. Individuals with an educational level under the primary school were more likely to suffer fall-related injuries, accounting for 72.66% of all deaths and 49.24% of nonfatal cases respectively. The annual burden of fall-related injuries equated to 25.90% of the share of GDP for the healthcare, social security and welfare industries in 2006. Conclusion Fall-related injuries were inversely related to victims＇ educational level. Children under the age of 5, women over 55 years old and men over 60 years old with an educational level lower than the primary school are the most risky groups of populations for intervention measures.

关键词： Fall Injury Education Costs Mortality

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Mechanism of Ta on the microstructure and properties of Fe-Mn damping alloys

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Tungsten 2024年第4期6卷 767-777页

作者： gui-xiang Liu Kun Zhang Chao Han Xiao-Lin Shao Jun Lu Lin Zhang Xiao-song Jiang Zi-Xuan Wu Liu Yang The Second Sub-Institute Nuclear Power Institute of China Key Laboratory of Advanced Technologies of Materials Ministry of Education School of Materials Science and Engineering Southwest Jiao tong University School of Engineering and Materials Science Queen Mary University of London Institute for Applied Materials (IAM-WK) Karlsruhe Institute of Technology (KIT)

Fe-Mn-Co-xTa alloys（x=0,1,2,3 wt.%） were fabricated using spark plasma sintering to explore the influence of Ta content on the microstructure,mechanical properties,and damping characteristics of Fe-17Mn-3Co damping *** micro structural analysis reveals the dominant presence of γ-austenite,ε-martensite,α'-martensite,and Co3Ta precipitates within the *** increments in Ta content exhibit proportional enhancements in hardness,tensile strength,and fracture elongation of the ***,these improvements in mechanical attributes are closely correlated with the generated second-phase *** the Ta content increases,there is a gradual augmentation in the formation of Co3Ta within the ***,the damping property initially experiences an ascent followed by a subsequent decline with rising Ta *** damping behavior finds its origins in multiple mechanisms,including grain boundary damping stemming from reduced grain size,interfacial damping induced by the generated Co3Ta,and dislocation *** is noteworthy that the emergence of the secondary phase wields a dual impact on damping *** the one hand,the proliferation of the second phase fosters increased interfaces for energy *** the other hand,these interfaces give rise to compressive stresses,constraining interface movement and thus impeding damping property enhancement.

关键词： Damping Fe–Mn–Co Mechanical properties Spark plasma sintering Ta

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GATiT:An Intelligent Diagnosis Model Based on Graph Attention Network Incorporating Text Representation in Knowledge Reasoning

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Computers, Materials & Continua 2024年第9期80卷 4767-4790页

作者： Yu song Pengcheng Wu Dongming Dai Mingyu gui Kunli Zhang School of Computer and Artificial Intelligence Zhengzhou UniversityZhengzhou450001China

The growing prevalence of knowledge reasoning using knowledge graphs(KGs)has substantially improved the accuracy and efficiency of intelligent medical ***,current models primarily integrate electronic medical records(EMRs)and KGs into the knowledge reasoning process,ignoring the differing significance of various types of knowledge in EMRs and the diverse data types present in the *** better integrate EMR text information,we propose a novel intelligent diagnostic model named the Graph ATtention network incorporating Text representation in knowledge reasoning(GATiT),which comprises text representation,subgraph construction,knowledge reasoning,and diagnostic *** the text representation process,GATiT uses a pre-trained model to obtain text representations of the EMRs and additionally enhances embeddings by including chief complaint information and numerical information in the *** the subgraph construction process,GATiT constructs text subgraphs and disease subgraphs from the KG,utilizing EMR text and the disease to be *** differentiate the varying importance of nodes within the subgraphs features such as node categories,relevance scores,and other relevant factors are introduced into the text ***-passing strategy and attention weight calculation of the graph attention network are adjusted to learn these features in the knowledge reasoning ***,in the diagnostic classification process,the interactive attention-based fusion method integrates the results of knowledge reasoning with text representations to produce the final diagnosis *** results on multi-label and single-label EMR datasets demonstrate the model’s superiority over several state-of-theart methods.

关键词： Intelligent diagnosis knowledge graph graph attention network knowledge reasoning

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Evaluating the influence of sarcopenia and myosteatosis on clinical outcomes in gastric cancer patients undergoing immune checkpoint inhibitor

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World Journal of Gastroenterology 2024年第8期30卷 863-880页

作者： gui-Ming Deng Hai-Bin song Zhong-Ze Du Ying-Wei Xue Hong-Jiang song Yuan-Zhou Li Department of Gastrointestinal Surgery Harbin Medical University Cancer HospitalHarbin 150081Heilongjiang ProvinceChina Department of Radiology Harbin Medical University Cancer HospitalHarbin 150081Heilongjiang ProvinceChina

BACKGROUND The development and progression of gastric cancer(GC)are closely linked to the nutritional status of *** immunotherapy has been demonstrated to be clinically effective,the relationships of sarcopenia and myosteatosis with the use of immune checkpoint inhibitors(ICIs)in patients with gastric cancer remain to be *** We performed a retrospective study of patients who were undergoing immuno-therapy for *** the evaluation of sarcopenia,the optimal cut-off value for the skeletal muscle index was established using receiver operating characteristic analysis of data obtained from pre-treatment computed tomography images at the L3 vertebral *** was defined using the mean skeletal muscle density(SMD),with a threshold value of<41 Hounsfield units(HU)for patients with a body mass index(BMI)<25 kg/m^(2)and<33 HU for those with a BMI≥25 kg/m^(2).The log-rank test was used to compare progression-free survival(PFS)and overall survival(OS),and a Cox proportional hazard model was used to identify prognostic *** were developed to predict the PFS and OS of patients on the basis of the results of multivariate *** We studied 115 patients who were undergoing ICI therapy for GC,of whom 27.4%had sarcopenia and 29.8%had *** with sarcopenia or myosteatosis had significantly shorter PFS and OS than those without these ***,both sarcopenia and myosteatosis were found to be independent predictors of PFS and OS in patients with GC administering an *** prediction models created for PFS and OS were associated with C-indexes of 0.758 and 0.781,*** The presence of sarcopenia or myosteatosis is a reliable predictor of the clinical outcomes of patients with GC who are undergoing treatment with an ICI.

关键词： Gastric cancer Sarcopenia Myosteatosis,Immune checkpoint inhibitor Prognostic factor Overall survival Progression-free survival

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Application of CFD and FEA Coupling to Predict Structural Dynamic Responses of A Trimaran in Uni-and Bi-Directional Waves

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China Ocean Engineering 2024年第1期38卷 81-92页

作者： LIAO Xi-yu XIA Jin-song CHEN Zhan-yang TANG Qin ZHAO Nan ZHAO Wei-dong gui Hong-bin Marine Design&Research Institute of China Shanghai 200011China Ship Structure Division China Ship Scientific Research CenterWuxi 214082China College of Ocean Engineering Harbin Institute of TechnologyWeihaiWeihai 264209China State Key Laboratory of Structural Analysis Optimization and CAE Software for Industrial EquipmentDalian University of TechnologyDalian 116024China School of Foreign Studies Jiangnan UniversityWuxi 214122China

To predict the wave loads of a flexible trimaran in different wave fields,a one-way interaction numerical simulation method is proposed by integrating the fluid solver(Star-CCM+)and structural solver(Abaqus).Differing from the existing coupled CFD-FEA method for monohull ships in head waves,the presented method equates the mass and stiffness of the whole ship to the hull shell so that any transverse and longitudinal section stress of the hull in oblique waves can be ***,verification study and sensitivity analysis are carried out by comparing the trimaran motions using different mesh sizes and time step *** on the wave elevation of uni-and bi-directional waves is also carried *** a comprehensive analysis on the structural responses of the trimaran in different uni-directional regular wave and bi-directional cross sea conditions is carried out,***,the differences in structural response characteristics of trimaran in different wave fields are *** results show that the present method can reduce the computational burden of the two-way fluid-structure interaction simulations.

关键词： CFD-FEA fluid-structure coupling structural responses trimaran bi-directional cross sea

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Earth-abundant Zn-dipyrrin chromophores for efficient CO2 photoreduction

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National Science Review 2024年第6期11卷 214-222页

作者： song Guo Fu-gui Zeng Xiao-Di Li Kai-Kai Chen Ping Wang Tong-Bu Lu Zhi-Ming Zhang Institute for New Energy Materials and Low Carbon Technologies School of Materials Science& Engineering Tianjin University of Technology

The development of strong sensitizing and Earth-abundant antenna molecules is highly desirable for CO2reduction through artificial photosynthesis. Herein, a library of Zn–dipyrrin complexes（Z-1-Z-6） are rationally designed via precisely controlling their molecular configuration to optimize strong sensitizing Earth-abundant photosensitizers. Upon visible-light excitation, their special geometry enables intramolecular charge transfer to induce a charge-transfer state, which was first demonstrated to accept electrons from electron donors. The resulting long-lived reduced photosensitizer was confirmed to trigger consecutive intermolecular electron transfers for boosting CO2-to-CO conversion. Remarkably, the Earth-abundant catalytic system with Z-6 and Fe-catalyst exhibits outstanding performance with a turnover number of >20 000 and 29.7% quantum yield, representing excellent catalytic performance among the molecular catalytic systems and highly superior to that of noble-metal photosensitizer Ir（ppy）2（bpy）+under similar conditions. Experimental and theoretical investigations comprehensively unveil the structure–activity relationship, opening up a new horizon for the development of Earth-abundant strong sensitizing chromophores for boosting artificial photosynthesis.

关键词： Zn complex photocatalysis CO2 reduction charge transfer photosensitizer

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Vertebral Artery Stenting for Acute Multiple Cerebral Infarctions Caused by Vertebral Artery Dissection After Massage:A Case Report

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Chinese Medical Sciences Journal 2024年第2期39卷 149-154页

作者： Ying-Xue Cui Chuan-Jin song Xue-Si Hou gui-Lin Liu Xu Ji Shao-song Wang Department of Neurology Beijing Hospital of Traditional Chinese MedicineCapital Medical UniversityBeijing 100010China

Vertebral artery dissection is a rare pathology that can cause ischemic stroke in young *** massage,especially improper pulling manipulation,is a cause of vertebral artery *** present a case of 32-year old woman who developed acute multiple posterior circulation ischemic cerebral infarctions as a result of left vertebral artery V4 segment dissection after receiving neck *** underwent emergency vertebral artery stent implantation at the site of the *** were relieved the day after *** patient recovered without adverse complications or endovascular restenosis in the following year.

关键词： vertebral artery dissection acute ischemic stroke stent implantation endovascular therapy

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Constructing high-capacity and flexible aqueous zinc-ion batteries with air-recharging capability using organic cathodes

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Chinese Chemical Letters 2024年第3期35卷 468-472页

作者： Xiaojuan Chen Haoqi Su Baozhu Yang Xiaocen Liu Xiuting song Lixin Su gui Yin Qi Liu Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology Advanced Catalysis Green Manufacturing Collaborative Innovation Center and School of Petrochemical EngineeringChangzhou UniversityChangzhou 213164China State Key Laboratory of Coordination Chemistry Nanjing UniversityNanjing 210093China

Flexible aqueous zinc-ion batteries(AZIBs)with air-recharging capability are a promising self-powered system applied in future wearable *** is desired to develop high-capacity air-rechargeable ***,we developed a flexible AZIB with air-recharging capability based on trinitrohexaazatrinaphthylene(TNHATN)cathode and a ZnSO_(4)*** flexible Zn//TNHATN battery exhibits high volumetric energy density(21.36 mWh/cm^3)and excellent mechanical ***,the discharged flexible Zn//TNHATN battery can be chemical self-charged via the redox reaction between TNHATN cathode and O_(2)from the *** oxidation in air for 15 h,such flexible Zn//TNHATN battery can deliver a high specific capacity of 320 mAh/g at 0.5 A/g,displaying excellent air-recharging ***,this flexible Zn//TNHATN battery also works well in chemical or/and galvanostatic charging mixed modes,showing *** work provides a new insight for designing flexible aqueous self-powered systems.

关键词： Aqueous zinc-ion battery Trinitrohexaazatrinaphthylene Organic cathode materials Flexible air-rechargeable battery Self-powered system

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Pedestrian Injuries and the Relevant Burden in Shanghai, China: Implications for Control

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Biomedical and Environmental Sciences 2015年第2期28卷 127-135页

作者： LI Yan Hong WANG Chun Fang song gui xiang PENG Juan Juan ZHOU De Ding SU Hui Jia GAO Ning YU Yan ZHONG Wei Jian ZHANG Hong Wei Department of Injury Prevention and Control Shanghai Municipal Center for Disease Control & Prevention Department of Vital Statistics Shanghai Municipal Center for Disease Control &Prevention Department of Epidemiology Second Military Medical University

Objective To study the associations of pedestrian injuries with age, income and educational level in Shanghai and to analyze the relative disease burden. Methods Information on pedestrian-related cases and deaths were collected from 494 hospitals and mortality registry systems from 1992 to 2010, and a multistage cluster sampling survey conducted in 2006. Logistic regression model was used in the analyses. Results The age group of 5-9 had the highest mortality and morbidity among children. Mortality increased obviously among those aged 60 or above. Individuals with an educational level under the primary school and with the lower family average income were more likely to suffer pedestrian-related injuries. Multivariate Logistic analysis demonstrated that lower income and lower educational level increased the risk of pedestrian injuries with the odds ratio of 1.40 （95% Cl： 1.15-1.71） and 1.70 （95% Cl： 1.20-2-40）, respectively. About 13.54% of the share of GDP for the healthcare, social security and welfare industries in Shanghai was occupied by the burden of pedestrian-related injuries in 2006. Conclusion Pedestrian-related injury has inverse association with victims＇ income and educational level. Children of 5-9 years old and adults over 60 with lower educational level and lower monthly income are the target persons to be intervened.

关键词： Pedestrian Injury Mortality Education Costs

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circRNA3669 promotes goat endometrial epithelial cells proliferation via miR-26a/RCN2 to activate PI3K/AKT-mTOR and MAPK pathways

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Journal of Integrative Agriculture 2024年第3期23卷 960-974页

作者： Xiaorui Liu Jiuzeng Cui Mengyao Wei Xiaofei Wang Yuexia Liu Zhongshi Zhu Min Zhou gui Ba Langda Suo Yuxuan song Lei Zhang Division of Laboratory Safety and Services Northwest A&F UniversityYangling 712100China College of Animal Science and Technology Northwest A&F UniversityYangling 712100China Institute of Animal Sciences Tibet Academy of Agricultural and Animal Husbandry SciencesLhasa 850009China

The development of receptive endometrium(RE) from pre-receptive endometrium(PE) for successful embryo implantation is a complex dynamic process in which the morphology and physiological states of the endometrial epithelium undergo a series of significant changes, including cell proliferation and apoptosis. However, the molecular mechanisms are not yet fully understood. In this study, a higher circRNA3669 level was observed in PE than in RE of goats. Functional assays revealed that this overexpression promoted the proliferation of goat endometrial epithelial cells(GEECs) by activating the expression of genes related to the PI3K/AKT-mTOR and MAPK pathways,thereby inhibiting apoptosis in vitro. Furthermore, circRNA3669 functioned as a competing endogenous RNA(ceRNA) to upregulate Reticulocalbin-2(RCN2) expression at the post-transcriptional level by interacting with and downregulating miR-26a in GEECs. In addition, RCN2, which is highly expressed in the PE of goats, was found to be regulated by β-estradiol(E2) and progesterone(P4). Our results demonstrated that RCN2 also affected the key proteins PI3K, AKT, mTOR, JNK, and P38 in the PI3K/AKT-mTOR and MAPK pathways, thereby facilitating GEECs proliferation and suppressing their apoptosis in vitro. Collectively, we constructed a new circRNA3669-miR-26aRCN2 regulatory network in GEECs, which further provides strong evidence that circRNA could potentially play a crucial regulatory role in the development of RE in goats.

关键词： circRNA3669 RCN2 miR-26a goat endometrial epithelial cells(GEECs) proliferation

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