检索结果-南通市图书馆

Agricultural Sciences 2021年第7期12卷 769-782页

作者： Juventine B. Odoi Thomas l. Odong Clement A. Okia john Bosco lomoris Okulo Moses Okao Harriet Kabasindi Alice Mucugi Samson Gwali National Forestry Resources Research Institute (NaFORRI) National Agricultural Research Organization (NARO) Kampala Uganda Department of Crop Production College of Agricultural and Environmental Sciences Makerere University Kampala Uganda World Agroforestry (ICRAF) Nairobi Kenya Muni University Arua Uganda Ngetta Zonal Agricultural Research and Development Institute (NettaZARDI) Lira Uganda Faculty of Natural Resources and Environmental Sciences Busitema University Busia Uganda

We studied seed germination and seedling growth performance in an economically and socially important fruit tree species Vitellaria paradoxa C.F. Gaertn. subsp. nilotica (shea tree) in Uganda. The study aimed at determining variations in germination among five shea tree seed provenances and seedling growth performance based on five growth traits (total height, root collar diameter, leaf length, leaf width and leaf petiole length). Five populations were considered from four agroecological zones comprising of 180 candidate “plus” trees. The seed trees consisted of 16 ethnovarieties selected based on their traits for fast growth and high oil yield. A total of 1,204 biological seeds were collected and sown in a tree nursery at Ngetta Zonal Agricultural Research and Development Institute during the month of June 2018 in a randomized incomplete block design with three replications. Significant variation (χ = 708;p ling phenotypic traits within and between populations. Regression equation for height growth and leaf size index were given as y = 0.3787 + 12.671x and y = 0.6483 + 15.413x respectively. Root collar diameter was more correlated to leaf size index (0.425) than to height growth (0.30). Clustering of shea tree seedlings based on phenotypic growth traits revealed one aggregated cluster indicating that most of the seedlings from the five populations were similar (Jaccard index 0.92, p lustering based on SNP markers revealed three different populations. We recorded higher growth (χ = 708;p lation. Red seeded;thin pulped and hairy fruited shea tree ethnovarieties recorded faster growth than the rest. The results reveal useful traits in selection for tree growth and further identified shea tree ethnovarieties that could be selected for fast growth.

关键词： Ethnovarieties Plantlets Root Collar Diameter leaf Size Index Population Cluster

Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2022年第7期19卷 834-847页

作者： Wenshu Tang Jingying Zhou Weiqin yang yu Feng Haoran Wu Myth T.S.Mok lingyun Zhang Zhixian liang Xiaoyu liu Zhewen Xiong Xuezhen Zeng Jing Wang Jiahuan lu Jingqing li Hanyong Sun Xiaoyu Tian Philip Chun yeung yong Hou Heung Man lee Candice C.H.lam Howard H.W.leung Anthony W.H.Chan Ka Fai To john Wong Paul B.S.lai Kelvin K.C.Ng Simon K.H.Wong Vincent W.S.Wong Alice P.S.Kong Joseph J.y.Sung Alfred S.l.Cheng school of Biomedical Sciences The Chinese University of Hong KongHong Kong SAR 999077China Department of Anatomical and Cellular Pathology The Chinese University of Hong KongHong Kong SAR 999077China Department of liver Surgery Ren Ji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of Surgery The Chinese University of Hong KongHong Kong SAR 999077China Department of Medicine and Therapeutics The Chinese University of Hong Kong.Hong Kong SAR 999077China State Key laboratory of Digestive Disease The Chinese University of Hong KongHong Kong SAR 999077China lee Kong Chian School of Medicine Nanyang Technological UniversitySingapore 639798Singapore Institute of Precision Medicine The First Affliated HospitalSun Yat-sen UniversityGuangzhou 510080China

Obesity is a major risk factor for cancers including hepatocellular carcinoma(HCC)that develops from a background of non-alcoholic fatty liver disease(NAFlD).Hypercholesterolemia is a common comorbidity of *** cholesterol biosynthesis mainly occurs in the liver,its role in HCC development of obese people remains *** high-fat high-carbohydrate diet-associated orthotopic and spontaneous NAFlD-HCC mouse models,we found that hepatic cholesterol accumulation in obesity selectively suppressed natural killer T(NKT)cell-mediated antitumor *** analysis of human liver revealed aberrant cholesterol metabolism and NKT cell dysfunction in NAFlD ***,cholesterol-lowering rosuvastatin restored NKT expansion and cytotoxicity to prevent obesogenic diet-promoted HCC ***,suppression of hepatic cholesterol biosynthesis by a mammalian target of rapamycin(mTOR)inhibitor vistusertib preceded tumor regression,which was abolished by NKT inactivation but not CD8^(+)T cell ***,sterol regulatory element-binding protein 2(SREBP2)-driven excessive cholesterol production from hepatocytes induced lipid peroxide accumulation and deficient cytotoxicity in NKT cells,which were supported by findings in people with obesity,NAFlD and *** study highlights mTORC1/SREBP2/cholesterol-mediated NKT dysfunction in the tumor-promoting NAFlD liver microenvironment,providing intervention strategies that invigorating NKT cells to control HCC in the obesity epidemic.

关键词： Cancer microenvironment Cancer models Tumour immunology

SHui, an EU-Chinese cooperative project to optimize soil and water management in agricultural areas in the ⅩⅪ century

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Soil and Water Conservation Research 2020年第1期8卷 1-14页

作者： José A.Gómez Alon Ben-Gal Juan J.Alarcón Gabrielle De lannoy Shannon de Roos Tomá(s)Dostál Elias Fereres Diego S.Intrigliolo Josef Krása Andreas Klik Gunther liebhard Reinhard Nolz Aviva Peeters Elke Plaas john N.Quinton Rui Miao Peter Strauss Weifeng Xu Zhiqiang Zhang Funing Zhong David Zumr Ian C.Dodd Institute for Sustainable Agriculture IASCSICAvda Menendez Pidal S/NCordobaSpain Agricultural Research Organization Gilat Research CenterIsrael Centro de Edafología y Biología Aplicada Del Segura(CSIC) Dept.RiegoMurciaSpain Department of Earth and Environmental Sciences KU LeuvenHeverleeBelgium Czech Technical University in Prague Faculty of Civil Engineering.CVUTPragueCzech Republic Agronomy Department University of CordobaCordobaSpain University of Agricultural Sciences Vienna(BOKU) ViennaAustria TerraVision lab Midreshet Ben-GurionIsrael Georg-August-Universitat Gottingen Germany Centre for Sustainable Agriculture Lancaster Environment CentreLancaster UniversityUK Center for Plant Water-Use and Nutrition Regulation and College of life Sciences Joint International Research Laboratory of Water and Nutrient in CropsFujian Agriculture and Forestry UniversityFuzhouChina Institute for land and Water Management Research Federal Agency for Water ManagementPetzenkirchenAustria College of Soil and Water Conservation Beijing Forestry UniversityBeijingChina College of Economics and Management Nanjing Agricultural UniversityNAUNanjingChina

This article outlines the major scientific objectives of the SHui project that seeks to optimize soil and water use in agricultural systems in the EU and China,by considering major current scientific challenges in this ***(for Soil Hydrology research platform underpinning innovation to manage water scarcity in European and Chinese cropping systems)is large cooperative project that aims to provide significant advances through transdisciplinary research at multiple scales(plot,field,catchment and region).This paper explains our research platform of long-term experiments established at plot scale,approaches taken to integrate crop and hydrological models at field scale;coupled crop models and satellite-based observations at regional scales;decision support systems for specific farming situations;and the integration of these technologies to provide policy recommendations through socio-economic analysis of the impact of soil and water saving *** also outlines the training of stake-holders to develop a basic common curriculum despite the subject being distributed across different disciplines and *** such,this article provides a review of major challenges for improving soil and water use in EU and China as well as information about the potential to access information made available by SHui,and to allow others to engage with the project.

关键词： yield Sustainability Cropping Cooperation

黑胫病弱毒种leptosphaeria biglobosa通过不同的信号途径诱导油菜抗性

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

西北农林科技大学学报（自然科学版） 2005年第B8期33卷 257-257页

作者：刘胜毅刘仁虎 Akinwunmi O latunde-Dada Hans Cools Huang y J Bruce D l Fitt john A lucas 中国农业科学院油料作物研究所基因组与分子生物学研究室湖北武汉430062 Rothamsted Research HarpendenHertfordshire AL5 2JQUK

油菜黑胫病是由两种类型病原引起的,分别为A型强致病株(***)和B型弱致病株,B型现命名为一个新种***.本试验研究了弱致病株诱导的针对强致病株的抗性及其分子信号途径.

关键词：黑胫病诱导的系统抗性甘蓝型油菜病害防御反应基因

Clinical Evaluation of an Oral Electrolyte Solution Formulated Based on Strong Ion Difference (SID) and Using Propionate as the Organic Anion in the Treatment of Neonatal Diarrheic Calves with Strong Ion Acidosis

在线全文

学校读者我要写书评

暂无评论

Open Journal of Veterinary Medicine 2012年第1期2卷 34-39页

作者： Henry Stampfli Olimpo Oliver john K. Pringle Department of Clinical Studies Ontario Veterinary College University of Guelph Guelph Canada Facultad de MedicinaVeterinaria y de Zootecnia Universidad Nacional de Colombia Bogota Colombia

Background: It is postulated that the concentrations of the major strong ions (Na, K, and Cl) in oral electrolyte solutions play a major role in clinical efficacy of these solutions for rehydration and corrections of metabolic acid base derangements. Objectives: The purpose of this study was to test prospectively the efficacy of an OES (OESexp) formulated based on concentration of strong ion difference (SID) and propionate in a group of calves with naturally occurring neonatal diarrhea and clinically detectable dehydration and acid base abnormalities. Animals: Ten client owned calves of varying breeds, 2 - 22 days old, presented to a veterinary teaching hospital with a history of naturally occurring acute undifferentiated diarrhea, progressive depression and dehydration for treatment. Methods: Clinical and laboratory parameters were measured pre and post two oral electrolyte treatments to assess efficacy of the experimental OES to correct clinical and clinico pathological parameters. For the clinical trial the calves served as their own controls. For control of safety of medication 4 normal calves were force fed 4 l of OESexp and followed over a 24 hour period. Results: All calves had severe diarrhea and metabolic acidosis. The metabolic acidosis observed in the plasma of these calves and reflected by pH, HCO3- SID and base deficit was corrected significantly towards reference ranges (p l feedings 12 hours apart. Dehydration was significantly corrected and all calves were discharged 1 - 3 days post admission. Conclusion and Clinical Importance: The use of SID is a valid approach when formulating oral electrolytes solutions for use in calves with acute diarrhea and metabolic derangement. Sodium propionate is valid substitute for commonly used sodium base equivalents in North America in oral electrolyte solutions.

关键词： Propionate Acid-Base Rehydration Strong Ions

From molecules to networks 2nd ed.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Inhibition of Rgs10 Expression Prevents Immune Cell Infiltration in Bacteria-induced Inflammatory lesions and Osteoclast-mediated Bone Destruction

丛书名：科爱传播.生命科学

2010年

作者： Byrne john H. Roberts James lewis

Includes bibliographical references and index.

ISBN: (纸本)9787030273932

Includes bibliographical references and index.

关键词： Molecular neurobiology. Cytology. Neurons.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Bone Research 2013年第3期1卷 267-281页

作者： Sen yang liang Hao Matthew McConnell Xuedong Zhou Min Wang yan Zhang john D Mountz Michael Reddy Paul D. Eleazer yi-Ping li Wei Chen Department of Pathology University of Alabama at BirminghamBirmingham Alabama USA The State Key laboratory of Oral Diseases West China College of Stomatology Sichuan University Department of Medicine University of Alabama at BirminghamBirmingham Alabama USA Department of Periodontology University of Alabama at Birmingham School of DentistryBirmingham Alabama USA Department of Endodontics University of Alabama at BirminghamBirmingham Alabama USA

Regulator of G-protein Signaling 10 （Rgsl0） plays an important function in osteoclast differentiation. However, the role of Rgsl0 in immune cells and inflammatory responses, which activate osteoclasts in inflam- matory lesions, such as bacteria-induced periodontal disease lesions, remains largely unknown. In this study, we used an adeno-associated virus （AAV-） mediated RNAi （AAV-shRNA-Rgs10） knockdown approach to study Rgsl0＇s function in immune cells and osteoclasts in bacteria-induced inflammatory lesions in a mouse model of periodontal disease. We found that AAV-shRNA-Rgs10 mediated Rgs10 knockdown impaired osteoclastogenesis and osteoclast-mediated bone resorption, in vitro and in vivo. Interestingly, local injection of AAV-shRNA-Rgs10 into the periodontal tissues in the bacteria-induced inflammatory lesion greatly decreased the number of dendritic cells, T-cells and osteoclasts, and protected the periodontal tissues from local inflammatory damage and bone destruction. Importantly, AAV-mediated Rgs10 knockdown also reduced local expression of osteoclast markers and pro-inflammatory cytokines. Our results demonstrate that AAV- shRNA-Rgs10 knockdown in periodontal disease tissues can prevent bone resorption and inflammation simultaneously. Our data indicate that Rgsl0 may regulate dendritic cell proliferation and maturation, as well as the subsequent stimulation of T-cell proliferation and maturation, and osteoclast differentiation and acti- vation. Our study suggests that AAV-shRNA-Rgs10 can be useful as a therapeutic treatment of periodontal disease.

关键词： Rgs10 immune cell AAV-mediated RNAi knockdown gene therapy periodontal disease gingivalinflammation bone resorption

^(60)Co γ射线辐照改性As_2S_3玻璃的纳米压痕试验（英文）

在线全文

学校读者我要写书评

暂无评论

硅酸盐学报 2016年第11期44卷 1636-1640页

作者： Taras KAVETSKyy Jaroslaw BORC Andrey l STEPANOV Drohobych Ivan Franko State Pedagogical University 24 I.Franko Str. 82100 Drohobych ne The john Paul II Catholic University of lublin 14 A1. Raciawickie 20-950 Lublin Poland lublin University of Technology 38 Nadbystrzycka Str. 20-618 Lublin Poland Kazan Physical-Technical Institute Russian Academy of Sciences 10/7 Sibirskiy Trakt 420029 Kazan Russia Kazan National Research Technological University 68 Karl Marx Str. 420015 Kazan Russia Kazan Federal University 18 Kremlevskaya Str. 420008 Kazan Russia

采用纳米压痕技术对^(60)Coγ-射线辐照改性10年后As_2S_3玻璃的表面机械性能(即硬度和弹性模量)进行超纳硬度仪(UNHT)测试,压痕深度为200~1 600 nm。结果表明:经平均量子能1.25 Me V、累计剂量2.41 MGy的^(60)Coγ-射线辐照后,g-As_2S_... 详细信息

采用纳米压痕技术对^(60)Coγ-射线辐照改性10年后As_2S_3玻璃的表面机械性能(即硬度和弹性模量)进行超纳硬度仪(UNHT)测试,压痕深度为200~1 600 nm。结果表明:经平均量子能1.25 Me V、累计剂量2.41 MGy的^(60)Coγ-射线辐照后,g-As_2S_3(g-表示玻璃态)的表面硬度和弹性模量与辐照前相比得以提高。对于g-As_2S_3表面机械性能的长期辐照诱导改性,具有辐照诱导氧化层的辐照样品与经过清洗和抛光处理除去氧化层的辐照样品相比,其实验数据显示宽分布特性。

关键词：硫系玻璃机械性能纳米压痕辐照改性

在线全文

学校读者我要写书评

暂无评论

生态环境曲面建模基本定理及其应用

中国科学：地球科学 2020年第8期50卷 1083-1105页

作者：岳天祥赵娜刘羽王轶夫张斌杜正平范泽孟史文娇陈传法赵明伟宋敦江王世海宋印军闫长青李启权孙晓芳张丽丽田永中王薇王英安马胜男黄宏胜卢毅敏王情王晨亮王玉柱鹿明周伟刘熠尹笑哲王宗包正义赵苗苗赵亚鹏焦毅蒙 Ufra NASEER 范斌李赛博杨阳 john P.WIlSON 中国科学院地理科学与资源研究所资源与环境信息系统国家重点实验室北京100101 中国科学院大学资源与环境学院北京100149 江西农业大学国土资源与环境学院南昌330045 山东科技大学测绘科学与工程学院青岛266590 北京林业大学林学院北京100083 西华师范大学国土资源学院南充637002 滁州学院地理信息与旅游学院滁州239000 中国科学院科技战略咨询研究院北京100190 山东科技大学信息工程系青岛266590 四川农业大学资源学院成都611130 曲阜师范大学地理与旅游学院日照276828 中国科学院空天信息创新研究院北京100094 西南大学地理科学学院重庆400715 国家减灾中心卫星遥感部北京100721 中国人口与发展研究中心人口数据部北京100081 国家标准化管理委员会工业二部北京100088 福州大学数字中国研究院福州350002 中国疾病预防控制中心环境与健康相关产品安全所北京100021 中国地质大学(北京)信息工程学院北京100083 钱学森空间技术实验室北京100094 重庆交通大学建筑与城市规划学院重庆400074 江苏省地理信息资源开发与利用协同创新中心南京210023 Spatial Sciences Institute University of Southern CaliforniaLos AngelesCA 90089-0374USA

在高精度曲面建模方法和地球表层系统建模基本定理研究结果基础上,演绎提出了生态环境曲面建模基本定理.以京津冀地区为案例,对基于生态环境曲面建模基本定理的空间升尺度、空间降尺度、空间插值、数据融合和模型-数据同化等算法进行了... 详细信息

在高精度曲面建模方法和地球表层系统建模基本定理研究结果基础上,演绎提出了生态环境曲面建模基本定理.以京津冀地区为案例,对基于生态环境曲面建模基本定理的空间升尺度、空间降尺度、空间插值、数据融合和模型-数据同化等算法进行了实证研究,与传统算法精度进行了比较分析.结果表明,由于基于生态环境曲面建模基本定理的各种算法综合了外蕴量信息和内蕴量信息,同时运用了理论上完善的信息综合方法,使海拔高度曲面的升尺度均方根误差至少降低了9m,年平均气温未来情景的降尺度精度至少提高16%,年平均气温过去变化趋势的数据融合精度至少提高70%,年平均降雨量过去变化趋势的空间插值精度至少提高0.2%,碳储量的模型-数据同化精度提高了40%.文章最后讨论了生态曲面建模基本定理亟待解决的五大理论问题和四大应用基础问题.

关键词：高精度曲面建模生态环境曲面建模基本定理空间升尺度空间降尺度空间插值数据融合模型-数据同化模型耦合