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Healing property of the Piper betel phenol, allylpyrocatechol against indomethacin-induced stomach ulceration and mechanism of action

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World Journal of Gastroenterology 2007年第27期13卷 3705-3713页

作者： S Bhattacharya D Banerjee AK Bauri S Chattopadhyay sk bandyopadhyay Department of Biochemistry Dr. B.C. Roy Post Graduate Institute of Basic Medical Sciences IPGME&R 244B Acharya Jagadish Chandra Bose Road Kolkata-700020 India Bio-Organic Division Bhabha Atomic Research Centre Mumbai-400085 India

AIM：To evaluate the protective activity of allylpyrocatechol （APC）, the major antioxidant constituent of Piper betel, against the indomethacin-induced stomach ulceration in the rat model and correlates with its antioxidative and mucin protecting properties.METHODS： Male Sprague-Dawley rats were divided into five groups. Normal control rats （group Ⅰ ） were given the vehicle oral dose of gum acacia in distilled water （1 mL per rat）; ulcerated control and treated rats （groups Ⅱ-V） were given a single dose of indomethacin （30 mg/kg body wt.）; group Ⅱ rats were sacrificed 4 h after indomethacin administration; groups Ⅲ-Ⅴ rats were given the vehicle （1 mL per rat） or APC （2 mg/kg body wt.） or misoprostol （1.43 μg/kg body wt.） once daily by oral intubation for 7 d starting from 4 h after the indomethacin administration. After 7 d, the stomach tissues were excised for histological examination and biochemical analysis. RESULTS： Treatment with APC （2 mg/kg body wt per day） and misoprostol （1.43 μg/kg body wt per day） for 7 d could effectively heal the stomach ulceration as revealed from the ulcer index and histopathological studies. Compared to the zero day ulcerated group, treatment with APC and misoprostol reduced the ulcer index by 93.4% and 85.4% respectively （P 〈 0.05）. Both APC and misoprostol accelerated ulcer healing observed in natural recovery （P 〈 0.05）, their respective healing capacities not being significantly different. The healing capacities of APC and misoprostol could be attributed to their antioxidant activity as well as the ability to enhance the rnucin content of the gastric tissues. Compared to the ulcerated untreated rats, those treated with APC and rnisoprostol showed near normal MDA levels, while the protein levels were 86% and 78% of the normal value respectively （P 〈 0.05）. Likewise, both APC and rnisoprostol increased the SOD, catalase, and rnucin levels significantly （P 〈 0.05）, the effect of APC being better. CONCLUSION： APC can protect ind

关键词： Allylpyrocatechol Antioxidant Histopathology Indornethacin Mucin Piper betel Stomach ulcer

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Detection of canine echinococcosis by coproantigen ELISA

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Asian Pacific Journal of Tropical Medicine 2010年第7期3卷 519-522页

作者： De S Pan D Bera AK Sreevatsava V Das sk Das S Rana T bandyopadhyay S Bhattacharya D Indian Veterinary Research Institute Eastern Regional Station37 Belgachia Road.Kolkata-700037India NRC on Yak DirangArunachal PradeshIndia Indian Veterinary Research Institute.Eastern Regional Station.37 Belgachia Road Kolkata-700037India

Objective:To study the canine echinococcosis by coproantigen ELISA ***:During the present investigation experimental infection was established using evaginated worms of Echinococcus granulosus(***).To check cross reactivity two pups were infected with Taenia hydatigena(***).In order to detect the presence of antigen,hyperimmune sera were raised against excretory-secretory products of adult worms *** granulosus. Faecal sample collected either from experimentally infected pups or from other sources were heated at 70℃to detect heat stable soluble ***:Pups harbouring less than 104 worms showed negative *** collected from 14 days onwards from experimentally infected animals harbouring more than 104 worms showed positive *** maximum positive samples were detected in samples collected from in and around slaughter house and the least number of samples were detected positive maintained by dog ***:The affinity purified IgG exhibited promising results for detection of canine echinococcosis by indirect ELISA.

关键词： Echinococcus granulosus Coproantigen ELISA Canine

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Internal States of Temperature Hysteresis in Shape Memory Alloys

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Journal of Materials Science & Technology 1997年第3期13卷 206-210页

作者： Xu, HB Gong, sk Dept. of Materials Science and Engineering Beijing University of Aeronautics and Astronautics Beijing 100083 China

We propose a thermodynamic theory that permits us to connect the size of the temperature hysteresis loop to the interfacial energy between martensite and austenite. The free energy is a function of four variables, viz. deformation of austenite, deformation of martensite, phase fraction and temperature. A diagonal line inside the hysteresis loop in the deformation-temperature diagram is identified as the line of unstable phase equilibrium. Upon reaching this line the phase mixture loses its (meta-)stability, and the transformation from one phase to the other should occur. The theoretical results are supported by experiments on NiTi and CuAlNi specimens.

关键词： Shape memory effect

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Radial basis function‐based exoskeleton robot controller development

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IET Cyber-Systems and Robotics 2022年第3期4卷 228-250页

作者： sk Hasan Department of Mechanical and Manufacturing Engineering Miami UniversityOxfordOhioUSA

The realisation of a model‐based controller for a robot with a higher degree of freedom requires a substantial amount of computational power.A high‐speed CPU is required to maintain a higher sampling *** processors cannot boost the performance or reduce the execution time as the programs are sequentially *** neural network is a great tool to convert a sequentially structured program to an equivalent parallel architecture *** this study,a radial basis function(RBF)neural network is developed for controlling 7 degrees of freedom of the human lower extremity exoskel-eton robot.A realistic friction model is used for modelling joint *** trajectory tracking accuracies have been *** of computational efficiency has been *** stability analysis of the developed controller is *** of variance is used to assess the controller's resilience to parameter *** show the effectiveness of the developed controller,a comparative study was performe between the developed RBF network‐based controller and Sliding Mode Controller,Computed Tor-que Controller,Adaptive controller,Linear Quadratic Regulator and Model Reference Computed Torque Controller.

关键词： exoskeleton robot dynamic modelling lower extremity exoskeleton robot control radial basis function(RBF)controller

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Electrochemical characterization of Ni-Co and Ni-Co-Fe for oxidation of methyl alcohol fuel with high energetic catalytic surface

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燃料化学学报 2014年第1期42卷 87-95页

作者： Subir Paul sk Naimuddin Asmita Ghosh Department of Metallurgical and Material Engineering Jadavpur University

Non Pt based metals and alloys as electrode materials for methyl alcohol fuel cells have been investigated w ith an aim of finding high electrocatalytic surface property for the faster electrode *** w ere fabricated by electrodeposition on pure Al foil,from an electrolyte of Ni,Co,Fe *** optimum condition of electrodeposition w ere found out by a series of experiments,varying the chemistry of the electrolyte,pH valve,temperature,current and cell *** study of the coated Ni-Co or Ni-CoFe alloy on pure Al w as found to exhibit high exchange current density,indicating an improved electro catalytic surface w ith faster charge-discharge reactions at anode and cathode and low *** impedance studies on coated and uncoated surface clearly show ed that the polarization resistance and impedance w ere decreased by Ni-Co or Ni-Co-Fe coating.X-ray diffraction(XRD),energy dispersive X-ray spectroscopy(EDX)and atomic absorption spectroscopy(AAS)studies confirmed the presence of alloying elements and constituents of the *** morphology of the deposits from scanning electron microscope(SEM)images indicated that the electrode surface w as a three dimensional space w hich increased the effective surface area for the electrode reactions to take place.

关键词： electrodeposition Ni-Co alloy electrocatalytic exchange current density impedance X-ray diffraction(XRD) scanning electron microscope(SEM)

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A New Route to S-(-)Zearalenone

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Chinese Chemical Letters 1997年第7期8卷 591-594页

作者： Wang, ZQ Tian, sk CHINESE ACAD SCI SHANGHAI INST ORGAN CHEMSHANGHAI 200032PEOPLES R CHINA

A concise synthesis of naturally occurring S-(-)-zearalenone has been described.

关键词： THF A New Route to S Zearalenone

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Characterization of Oxygen Species on MgO(100) Surface by XPS andSRPES

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Chinese Chemical Letters 1996年第11期7卷 1059-1060页

作者： Da, JW Shen, sk QILU PETROCHEM CO RES INSTZIBO SHANDONG 245400PEOPLES R CHINA

The present work reported the results of the characterization of the surface oxygen species on single crystal MgO(100) using surface sensitive analyzing methods ARXPS(angular resolved X-ray photoelectron spectroscopy)... 详细信息

关键词： XPS Characterization of Oxygen Species on MgO Surface by XPS andSRPES

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Microstructure, Impact Toughness and TEM Analysis in the CGHAZ of HQ130 High Strength Steel

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Journal of Materials Science & Technology 1999年第6期15卷 555-558页

作者： Zou, ZD Li, YJ Yin, sk Shandong Univ Technol Jinan 250061 Peoples R China

Microstructure and impact toughness in the coarse grain heat-affected zone (CGHAZ) of HQ130 high strength steel were studied by using the weld thermo-simulation test. Fracture morphology and fine structure in the CGHAZ were analyzed by means of SEM, TEM and electron diffraction. Experimental results indicated that the impact toughness and hardness in the CGHAZ (T-m = 1350 degrees C) decreased with increasing cooling time (t(8/5)), and fracture morphology changed from dimple fracture into cleavage fracture. The reason for the toughness decrease is the formation of upper bainite. During application, the welding heat input should be strictly limited, to reduce brittleness in the CGHAZ of HQ130 steel.

关键词： Steel

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Revisiting Conserved Currents in the F(R)Theory of Gravity via Noether Symmetry

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Chinese Physics Letters 2013年第2期30卷 41-45页

作者： Nayem sk. Abhik Kumar Sanyal Deptment of Physics University of KalyaniNadia 741235India Deptment of Physics Jangipur CollegeMurshidabad 742213India

Noether symmetry of the F(R)theory of gravity in a vacuum and in the presence of pressureless dust yields F(R)∝R^(3/2) along with the conserved current d/dt(a√R)in the Robertson-Walker metric and nothing ***,some authors recently claimed to have obtained four conserved currents setting F(R)∝R^(3/2) a-priori,taking time translation along with a gauge *** show that the first one of these does not satisfy the field equations and the second one is the Hamiltonian which is constrained to vanish in gravity and thus a part and parcel of the field *** also show that the other two conserved currents,which do not contain time translation,are the same in disguise and identical to the one mentioned *** the claim is wrong.

关键词： conserved satisfy mentioned

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Interfacial instability of sand patterns induced by turbulent shear flow

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International Journal of Sediment Research 2021年第4期36卷 449-456页

作者： sk Zeeshan Ali Subhasish Dey Department of Civil Engineering Indian Institute of Technology Hyderabad Department of Civil Engineering Indian Institute of Technology Kharagpur Department of Hydraulic Engineering State Key Laboratory of Hydro-Science and Engineering Tsinghua University

When a turbulent shear flow above a plane sand surface entrains sand grains, it generates a variety of sand patterns. Fluvial sand forms two major interfacial patterns: meso-scale dunes and antidunes, and large-scale bars. Measurements have evidenced that under erosive conditions, meso-scale patterns either change to or coexist with large-scale patterns. However, it remains elusive what exactly drives the switching of interfacial patterns and how the switching occurs. Here, we showdcombing a flow model with a grain transport model, allowing for both the surface and suspended sand fluxes dthat the switching of patterns emerges from the shear-driven complex feedback between grain transport and topographic perturbations. The switching predominantly depends on the magnitudes of the Rouse number and the grain size to undisturbed flow depth ratio. The model offers quantitative predictions of the maximum amplification of sand patterns and unveils a new attraction erepulsion phenomenon.

关键词： Instability Sand patterns Turbulent flow Sediment transport

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