检索结果-南通市图书馆

Cork冠状动脉疾病病例对照研究中急性冠状动脉综合征和慢性感染的关系

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（心脏病学分册） 2005年第5期1卷 50-51页

作者： Sheehan J. Kearney P.m. Sullivan S.O. 陶蕾 Dept. of Epidem.ol. and Pub. Health University College Cork Cork Ireland Dr.

Objective: To exam.ne the association between chronic infection and cum.lative burden of infection and acute coronary syndrom.. Design: The 5C(Cork coronary care case-control)-study was a com.unity based case-control study. Patients and controls underwent a standard physical exam.nation and had blood sam.les taken for serological analysis for Helicobacter pylori(IgG), Chlam.dia pneum.niae(IgA, Igm. and IgG), cytom.galovirus(IgG), and herpes sim.lex virus types 1 and 2(IgG). Setting: Patients were recruited from.four hospitals in Cork City and mal lowTown, Controls, individually m.tched on age and sex, were selected by incident density sam.ling from.the sam. general practices as the referent case. m.in outcom. m.asures: Age and sex adjusted and fully adjusted odds ratios for acute coronary syndrom. by seropositivity and by increasing num.er of infections. Results: Cases and controls did not differ significantly in seropositivity to C pneum.niae, cytom.galovirus, herpes sim.lex viruses, and H pylori. In unconditional logistic regression analysis adjusted for age, sex, waist to hip ratio, sm.king, physical activity, alcohol consum.tion, and social class there was no evidence of an increasing risk for acute coronary syndrom. with increasing burden of infection. Conclusions: The findings do not support an association between specific infectious agents and acute coronary syndrom. and do not provide evidence of a burden of infection effect.

关键词： Cork 病例对照研究肺炎衣原体感染数血清学阳性综合医疗机构 IgG 巨细胞病毒体格检查单纯疱疹病毒

量热滴定法研究TOPO与Ln（Pm.P）3三元络合反应

在线全文

学校读者我要写书评

暂无评论

中国稀土学报 1984年第2期 1-8页

作者：王文清,刘清亮,m.S.Caceci,G.R.Choppin 北京大学中国科技大学美国佛罗里达州立大学美国佛罗里达州立大学

本文使用微型计算机控制的量热滴定仪直接测定了25℃下,TOPO（三辛基氧化膦）与镧系13个元素（除Ce和P m.）的Pm.P（1-苯基3-甲基-4苯甲酰基吡唑啉酮-5）的络合物在三元络合反应过程中产生的热量。实验发现生成两种三元络合物Ln（Pm.P... 详细信息

本文使用微型计算机控制的量热滴定仪直接测定了25℃下,TOPO（三辛基氧化膦）与镧系13个元素（除Ce和P m.）的Pm.P（1-苯基3-甲基-4苯甲酰基吡唑啉酮-5）的络合物在三元络合反应过程中产生的热量。实验发现生成两种三元络合物Ln（Pm.P）3·TOPO和Ln（Pm.BP）3（TOPO）2。使用*** 的机算机程序和最小二乘分析的反复运算技术,进行了500或1000次拟合,使标准偏差达到指定要求,求出三元络合反应的 △H2、△H1、lgβ1、lgβ2,并算得了络合反应的熵变 △S1和△S2。实验还发现,以 lgβ1、lgβ2,lgK2对镧系元素的原子序数作图,存在四分组效应。

关键词： Pm.P 络合物配位化合物 Ln 络合反应 TOPO 三元

瘦素逆转严重脂质营养不良患者的非酒精性脂肪肝

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（胃肠病学分册） 2005年第8期1卷 49-50页

作者： Javor E.D Ghany m.G Cochran E.K 王铮 m.C 1612 10 Center Dr. Bethesda MD 20892United States Dr

Severe lipodystrophy is characterized by dim.nished adipose tissue and hypolep tinem.a, leading to ectopic triglyceride *** the liver, this is asso ciated with steatosis,potentially leading to nonalcoholic steatohepatitis (NASH) . We investigated the prevalence of NASH and the effect of leptin replacem.nt in these patients. Ten patients with either generalized lipody strophy (8 patients ) or Dunnigan’s partial lipody strophy(2 patients) were included in this analys is. Paired liver biopsy specim.ns were obtained at baseline and after treatm.nt with recom.inant m.thionyl hum.n leptin (r-m.tHuLeptin), m.an duration 6.6 m.nt hs. The extents of portal and parenchymal in-flam.ation, steatosis, ballooning, presence of mallory bodies,and fibrosis in liver biopsy specim.ns were scored u sing a previously validated system.developed to assess NASH *** l disease activity was defined as the sum.of ballooning, steatosis, and parenchy mal inflam.ation scores. We concurrently tested serum.triglycerides and am.notra nsferases and estim.tions of liver volum. and fat content by m.gnetic resonance im.ging. Eight of 10 patients m.t histological criteria for NASH at baseline. Af ter treatm.nt with r-m.tHuLeptin,repeat histological exam.nations showed signif icant im.rovem.nts in steatosis (P = .006) and ballooning injury (P = .005),with a reduction of m.an NASH activity by 60%(P = .002).Fibrosis was unchanged. Significant re ductions were seen in m.an seru- m.triglycerides (1206→226m./dL, P = .002),glucose(220→144 m./dL, P = .02), i nsulin (46.4→24.8 μIU/m., P =.004), ALT (54→24U/L, P = .02), AST (47→22 U/L, P = .046),liver volum. (3209→2391 cm., P = .007), and liver fat content(31→11 %, P = .006). In conclusion, r-m.tHuLeptin therapy significantly reduced trigl ycerides, transam.nases, hepatom. egaly,and liver fat content. These reductions were associated with significant reductions in steatosis and the hepatocellular ballooning injury seen in NASH.

关键词：脂质营养不良酒精性脂肪肝脂肪变性 NASH 气球样变肝脏脂肪肝脏体积肝组织标本脂肪组织肝实质

宫颈鳞状上皮内病变与HIV血清学、CD4细胞计数及人乳头瘤病毒检测结果的关系

在线全文

学校读者我要写书评

暂无评论

世界核心医学期刊文摘（妇产科学分册） 2005年第8期1卷 1-2页

作者： Harris T.G. Burk R.D. Palefsky J.m. 张剑萍 Dr.Dept. of Epidem.ol. and Pop. Health Albert Einstein College of Medicine Belfer 1308A 1300 Morris Park Ave Bronx NY 10461 United States

Context: Recent cervical cancer screening guidelines state that the interval between screenings can be safely extended to 3 years in healthy wom.n 30 years or older who have normal cytology results and have negative test results for oncogenic hum.n papillom.virus (HPV)-DNA. Objective: To determ.ne the incidence of squam.us intraepithelial lesions (SILs) in HIV-seropositive wom.n with nor mal cytology results, by baseline HPV DNA results. Design, Setting, and Patients: Participants were HIV-seropositive (n = 855; m.an age, 36 years) and HIV-seronegative (n = 343; m.an age, 34 years) US wom.n with normal baseline cervical cytology who were enrolled in the Wom.ns Interagency HIV Study (WIHS), a large, m.lti-institutional prospective cohort study. Since their recruitm.nt during 1994-1995, WIHS participants have been followed up sem.-annually with repeated Pap sm.ars for a m.dian of 7 years. m.in Outcom. m.asure: The cum.lative incidence of any SIL and high-grade SIL or cancer (HSIL+) was estim.ted according to baseline HPV DNA results, stratified by HIV serostatus and CD4 T-cell count. Results: Developm.nt of any SIL in wom.n with negative HPV results (both oncogenic and nononcogenic) at 2 years was as follows: in HIV-seropositive wom.n with CD4 counts less than 200/μL, 9%(95%CI, 1%-18%); with CD4 counts between 200/μL and 500/μL, 9%(95%CI, 4%-13%); and with CD4 counts greater than 500/μL, 4%(95%CI, 1%-7%). The CIs for these estim.tes overlapped with those for HIV-seronegative wom.n with normal baseline cytology who were HPV-negative (3%; 95%CI, 1%-5%), indicating that at 2 years, there were no large absolute differences in the cum.lative incidence of any SIL between groups. Furtherm.re, no HPV-negative participants in any group developed HSIL+lesions within 3 years. m.ltivariate Cox m.dels showed that on a relative scale, the incidence of any SIL am.ng HIV-seropositive wom.n with CD4 counts greater than 500/μL (hazard ratio [HR], 1.2; 95%CI, 0.5-3.0), but not those w

关键词： CD4细胞计数人乳头瘤病毒 HIV 鳞状上皮内病变血清学巴氏涂片血清阳性致癌性累计发病率基线值

血小板活化状态与原发性肾病综合征患儿高凝状态的研究

在线全文

学校读者我要写书评

暂无评论

肾脏病与透析肾移植杂志 1999年第1期8卷 34-35页

作者：白晓玲郭卫民段晓辉许波孙晓明尹格平济南军区总医院儿科济南250031 首都医科大学附属北京友谊医院肾内科北京100050

目的：探讨原发性肾病综合征（ＮＳ）患儿血小板活化程度在诊断高凝状态中的价值。　方法：采用流式细胞仪检测３８例ＮＳ患儿外周血血小板颗粒膜蛋白（ＣＤ６２Ｐ）、溶酶体颗粒膜蛋白（ＣＤ６３）及凝血酶敏感蛋白（ＴＳＰ）... 详细信息

目的：探讨原发性肾病综合征（ＮＳ）患儿血小板活化程度在诊断高凝状态中的价值。　方法：采用流式细胞仪检测３８例ＮＳ患儿外周血血小板颗粒膜蛋白（ＣＤ６２Ｐ）、溶酶体颗粒膜蛋白（ＣＤ６３）及凝血酶敏感蛋白（ＴＳＰ），同时检测了血管内皮细胞标志、凝血、抗凝及纤溶指标。　结果：　与对照组比较，ＮＳ患儿肾病期血小板ＣＤ６２Ｐ、ＣＤ６３及ＴＳＰ表达率明显增高，缓解期接近正常，ＣＤ６２Ｐ、ＣＤ６３与ＰＡｇＴ、ＶＷＦ、ＰＡＩ及ＦＤＰ呈明显正相关，与ＡＴⅢ：Ａｇ、ＡＴⅢ：ａｃ呈明显负相关；ＴＳＰ与ＶＷＦ、ＰＡＩ正相关。结论：提示血小板活化与ＮＳ高凝状态的发生有关，ＣＤ６２Ｐ及ＣＤ６３为早期诊断高凝状态的敏感指标。

关键词：血小板肾病综合征高凝状态儿童

针刺对恶性肿瘤患者外周血T细胞及其亚群的影响

在线全文

学校读者我要写书评

暂无评论

针刺研究 1993年第3期18卷 174-177页

作者：元建国周荣兴周呜生龚其美华西医科大学附属第一医院针灸科成都610041 华西医科大学微生物及免疫教研室

本研究采用单克隆抗体技术对51例恶性肿瘤患者外周血T 细胞及其亚群进行了针刺前后的观察。实验设计了三个组:恶性肿瘤患者的针刺组和对照组,及正常人对照组。以 OKT_3、OKT_4,OKT_8及OKT_4/OKT_8为观察指标。结果表明,针刺治疗能够提... 详细信息

本研究采用单克隆抗体技术对51例恶性肿瘤患者外周血T 细胞及其亚群进行了针刺前后的观察。实验设计了三个组:恶性肿瘤患者的针刺组和对照组,及正常人对照组。以 OKT_3、OKT_4,OKT_8及OKT_4/OKT_8为观察指标。结果表明,针刺治疗能够提高恶性肿瘤患者外周血 T 细胞及其亚群的百分率,尤以 OKT_4^+细胞受针刺影响最明显。

关键词：针刺 T细胞亚群免疫 OKT 肿瘤

ASTUDY OF VALENCE OF YTTRIUm.IN Y_2O_3 m. CATHODE

在线全文

学校读者我要写书评

暂无评论

Acta m.tallurgica Sinica(English Letters) 1999年第4期12卷 602-606页

作者： J.S.Wang1,2) ,m.L.Zhou2) ,J.X.Zhang2) ,Z.R.Nie2) T.Y.Zuo2) and G.J.Zhang2) 1) State Key Laboratory of m.terials Chem.stry and Applications,Peking University ,Beijing 100871 ,China2) Schoolof m.terials Science and Engineering ,Beijing Polytechnic Univers

The valenceofelem.ntyttrium.of Y2 O3 m.cathode m.terialhasbeenstudied by usingther mal weight analysis, X ray diffraction analysis, Scanning electron m.croscopy and X rayphotoelectronspectrum.. It hasbeen provedthatyttrium.oxidecan bereduced by m.lybdenum. carbide. Thereaction between powdered Y2 O3 and m.2 Ccan happen at 1173 , and Y2 O3m.y bereduced to m.tallicyttrium.. Afterthepowder m.xtureof Y2 O3 and m.2 Cwasheat treated at1873 K, Yttrium.existsin two kinds of chem.calstate- yttrium.of zero valence and yttrium.ofthreevalences.

关键词： valence,yttrium Y2 O3 m.,cathode

在线全文

学校读者我要写书评

暂无评论

高能Pb离子在β-Sn中引起的辐照效应

高能Pb离子在β-Sn中引起的辐照效应