检索结果-南通市图书馆

High-Value-Added Utilization of Turpentine:Screening of Anti-Influenza Virus Agents fromβ-Pinene Derivatives

Journal of Renewable Materials 2024年第1期12卷 45-56页

作者： Yiwen Li hongyan si Peng Wang Hai Luo Minggui Shen Xiaoping Rao Zhanqian Song Shibin Shang Zongde Wang Shengliang Liao East China Woody Fragrance and Flavor Engineering Research Center of National Forestry and Grassland Administration Camphor Engineering Research Center of National Forestry and Grassland AdministrationCollege of ForestryJiangxi Agricultural UniversityNanchang330045China Institute of Chemical Industry of Forestry Products China Academy of ForestryNational Engineering Laboratory for Biomass Chemical UtilizationKey and Open Laboratory of Forest Chemical EngineeringState Forestry AdministrationKey Laboratory of Biomass Energy and MaterialJiangsu ProvinceNanjing210042China College of Chemical Engineering Huaqiao UniversityXiamen361021China

Turpentine is a renewable and resourceful forest *** deep processing and utilization of turpentine,particularly its primary componentβ-pinene,has garnered widespread *** study aimed to synthesize 40 derivatives ofβ-pinene,including nopinone,3-cyanopyridines of nopinone,myrtanyl acid,myrtanyl acylthioureas,and myrtanyl *** assessed the antiviral activities of theseβ-pinene derivatives against influenza virus A/Puerto Rico/8/34(H1N1)using the 3-(4,5-dimetylthiazol-2-yl)-2,5-diphenyltetrazolium bromide ***β-pinene derivatives were used before and after cellular infection with the influenza virus to evaluate their preventive and therapeutic effects against the H1N1 *** results showed that only compound 10o exhibited a preventive effect against the H1N1 virus with a half-maximal inhibitory concentration(IC50)value of 47.6μmol/*** the compounds,4e,4i,and 4l demonstrated therapeutic effects against cellular infection,with compound 4e displaying the most potent therapeutic effect(IC50=17.5μmol/L),comparable to the positive control *** findings indicated that certainβ-pinene derivatives exhibited in vitro antiviral activity against the H1N1 influenza A virus,warranting further investigation as potential anti-influenza agents.

关键词： Antiviral activity β-pinene derivative 3-cyanopyridine influenza virus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preparation of Amide-Containing Insecticidal Derivatives from the Renewable Natural Productβ-Pinene

引用

Journal of Renewable Materials 2023年第5期11卷 2368-2380页

作者： Jiulong Wang Yanqing Gao Xiaoping Rao Zongde Wang Shibin Shang Zhanqian Song hongyan si Shengliang Liao East China Woody Fragrance and Flavor Engineering Research Center of National Forestry and Grassland Administration Camphor Engineering Research Center of National Forestry and Grassland AdministrationCollege of ForestryJiangxi Agricultural UniversityNanchang330045China College of Plant Protection Northwest Agriculture and Forestry UniversityYangling712100China College of Chemical Engineering Huaqiao UniversityXiamen361021China Institute of Chemical Industry of Forest Products China Academy of ForestryNational Engineering Laboratory for Biomass Chemical UtilizationState Forestry Administration’s Key and Open Laboratory for Forest Chemical EngineeringJiangsu Provincial Key Laboratory for Biomass Energy and MaterialNanjing210042China

The preparation of bioactive derivatives from the renewable natural product pinene is a hot research topic in the deep processing and utilization of *** this study,β-pinene was used to develop novel molecules as a promising new precursor of insecticide.A series of amide-containing derivatives ofβ-pinene were synthesized and *** insecticidal activities of these derivatives against Mythimna separate and Semiaphis heraclei were *** structure characterization results showed that the characterization data of amide-containing derivatives were in full agreement with their proposed *** insecticidal activities evaluation results indicated that amide-containing derivatives exhibited weak insecticidal activity against Mythimna separate,but exhibited moderate to good insecticidal activity against Semiaphis *** testing for 72 h,the corrected mortality against Semiaphis heraclei of compounds 5c,5e,5f,5 h,5j,and 5 m was 100%at 1000 mg/*** structure-activity relationship analysis results showed that the introduction of an amide group into the structure of derivatives improved their insecticidal activity against Semiaphis ***,the amide-containing derivatives containing the F and NO_(2) substituted benzene ring might improve their insecticidal activity against Semiaphis *** study will be helpful for the high value-added utilization of the natural renewable resourceβ-pinene and the development of novel insecticides.

关键词： Turpentine pinene derivative amide insecticidal activity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Synthesis and anticancer activity of(+)-nopinone-based 2-amino-3-cyanopyridines

引用

Frontiers of Agricultural Science and Engineering 2015年第4期2卷 335-340页

作者： Shengliang LIAO Shibin SHANG Minggui SHEN Xiaoping RAO hongyan si Jie SONG Zhanqian SONG Institute of Chemical Industry of Forest Products China Academy of ForestryNational Engineering Laboratory for Biomass Chemical UtilizationState Forestry Administration’s Key and Open Laboratory for Forest Chemical EngineeringJiangsu Provincial Key Laboratory for Biomass Energy and MaterialNanjing 210042China Department of Chemistry and Biochemistry University of Michigan-FlintFlint MI 48502USA

Twelve(+)-nopinone-based 2-amino-3-cyanopyridines 4a-1 were synthesized from(–)-β-*** structures of these compounds were characterized by FT-IR,1H NMR,and *** the compounds were tested for their anticancer activity against lung cancer cell line A549,gastric cancer cell line MKN45 and breast cancer cell line MCF7 by MTT method,*** results showed that compounds 4f,4j and 4k had promising anticancer activity against these cancer cell lines,in particular,compound 4f exhibited broad-spectrum and highly efficient anticancer activity against cell lines A549,MKN45 and MCF7 with IC50 of 23.78,67.61 and 53.87μmol·L^(-1),*** preliminary analysis of the structure activity relationship implied that the Br or Cl substituted group of the benzene ring in these derivatives significantly contributed to the anticancer activity.

关键词： β-pinene nopinone synthesis 2-amino-3-cyanopyridine anticancer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

THE CONTROL OF JUNCTURE AND PROSODY IN CHINESE TTS SYSTEM

THE CONTROL OF JUNCTURE AND PROSODY IN CHINESE TTS SYSTEM

引用

1996 3rd International Conference on signal Processing(ICSP’96)

作者： CHU Min LU Shinan si hongyan HE Lin GUAN Dinghua Institute of Acoustics Academia Sinica

ISBN: (纸本)0780329120

＜正＞In a Chinese TTS system that is based on syllabic waveform concatenation,proper control of juncture between syllables and prosody of sentences is essential to improving the naturalness of the synthetic *** this paper, a perception experiment on fonnant transitions between syllables and a prosody model designed for Chinese TTS system are presented.

关键词： speech synthesis speech intelligibility natural languages juncture control prosody control Chinese TTS system syllabic waveform concatenation synthetic speech perception experiment formant transitions prosody model text to speech system

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

甘肃省初治肺结核患者耐药现状及耐多药影响因素分析

引用

中华流行病学杂志 2022年第7期43卷 1093-1098页

作者：马玲辜吉秀李晴李银花王冬冬何健司红艳甘肃省疾病预防控制中心结核病防治所兰州730020 甘肃省红十字血液中心兰州730000

目的:分析甘肃省初治肺结核患者耐药现状及其影响因素,为精准防控提供参考依据。方法:纳入2014年9月至2017年8月甘肃省30家结核病定点医疗机构(耐药监测点)初治肺结核患者,并进行问卷调查。临床分离的结核分枝杆菌进行异烟肼、利福平、... 详细信息

目的:分析甘肃省初治肺结核患者耐药现状及其影响因素,为精准防控提供参考依据。方法:纳入2014年9月至2017年8月甘肃省30家结核病定点医疗机构(耐药监测点)初治肺结核患者,并进行问卷调查。临床分离的结核分枝杆菌进行异烟肼、利福平、乙胺丁醇、链霉素、卡那霉素、阿米卡星、氧氟沙星、卷曲霉素、丙硫异烟胺和对氨基水杨酸钠10种抗结核药物表型药敏(比例法)鉴定。采用logistic回归模型分析耐多药结核病产生的危险因素。结果:1815例初治患者中,1例患者对应1株结核分枝杆菌,其中总耐药率、单耐药、多耐药、耐多药和广泛耐药率及其95%CI分别为25.45%(23.45%~27.46%)、11.40%(9.94%~12.87%)、6.23%(5.11%~7.34%)、7.82%(6.59%~9.06%)、0.28%(0.03%~0.52%);142例耐多药患者中,农民、20~59岁青壮年及低收入者分别占90.85%、62.68%、31.69%。单因素及多因素分析结果显示,男性、少数民族、治疗<1个月且停药<2个月为耐多药结核病的危险因素。结论:与全国平均水平相比,甘肃省初治患者总耐药率低,但耐多药率高。对农村低收入结核病患者提供救助是甘肃省遏制耐多药传播的重要策略,重点关注并解决患者治疗不规范及依从性差等问题。

关键词：肺结核耐多药影响因素

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

柠檬腈的合成工艺研究

引用

林产化学与工业 2022年第6期42卷 77-83页

作者：王九龙司红燕陈尚钘饶小平王宗德廖圣良江西农业大学林学院/国家林业草原木本香料(华东)工程技术研究中心江西南昌330045 华侨大学化工学院福建厦门361021

对柠檬醛催化氨氧化法制备柠檬腈的工艺进行优化,探讨了氨水(NH_(3)·H_(2)O)用量、过氧化氢(H_(2)O_(2))用量、反应时间、反应温度、催化剂的类型和用量以及溶剂的类型等因素对柠檬醛转化率和柠檬腈产率的影响。通过单因素试验和正交... 详细信息

对柠檬醛催化氨氧化法制备柠檬腈的工艺进行优化,探讨了氨水(NH_(3)·H_(2)O)用量、过氧化氢(H_(2)O_(2))用量、反应时间、反应温度、催化剂的类型和用量以及溶剂的类型等因素对柠檬醛转化率和柠檬腈产率的影响。通过单因素试验和正交试验优化得到柠檬腈的最佳合成工艺条件:柠檬醛35 mmol,n(柠檬醛)∶n(NH_(3)·H_(2)O)∶n(H2O2)∶n(CuCl)=1∶2.7∶5.5∶0.045,H_(2)O_(2)为氧化剂,CuCl为催化剂,36 mL异丙醇为溶剂,反应时间为5 h,反应温度为10~15℃。在该条件下,柠檬醛的平均转化率可达97.50%,柠檬腈的平均产率可达94.59%。对工艺条件分别放大2、3和5倍进行试验,柠檬醛的转化率分别为95.75%、95.05%和95.00%,柠檬腈的产率分别为92.88%、92.20%和92.15%。

关键词：柠檬醛柠檬腈氨化氧化工艺优化

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

淹水胁迫下6种北方花灌木光合特性及耐涝性评价

引用

植物生理学报 2024年第4期60卷 725-738页

作者：朱婧杨城刘思王茂良丛日晨孙宏彦北京市园林绿化科学研究院绿化植物育种北京市重点实验室城乡生态环境北京实验室北京100102 河北农业大学河北保定071001 涉县住房和城乡建设局城镇园林管理所河北邯郸056400 北京农学院北京102206

本研究以淹水胁迫0~15 d的重瓣榆叶梅、金钟花、水栒子、小花溲疏、圆锥绣球、欧洲荚蒾6种北方花灌木为试材,测定其根系生长、植株形态、光合气体交换和叶绿素荧光参数等变化。结果显示,重瓣榆叶梅、金钟花、水栒子、小花溲疏、圆锥绣球... 详细信息

本研究以淹水胁迫0~15 d的重瓣榆叶梅、金钟花、水栒子、小花溲疏、圆锥绣球、欧洲荚蒾6种北方花灌木为试材,测定其根系生长、植株形态、光合气体交换和叶绿素荧光参数等变化。结果显示,重瓣榆叶梅、金钟花、水栒子、小花溲疏、圆锥绣球5种花灌木根系干重、根总长、根表面积等根系指标随淹水时间的增加呈先增加后下降的趋势,欧洲荚蒾呈逐渐下降的趋势;6种花灌木的植物叶片的叶片含水率、比叶重、PsiI最大光合效率(Fv/Fm)、单位反应中心吸收的光能(RC/ABS)以及潜在光合转化和利用能力(PI)等叶绿素荧光指标及净光合速率(Pn)、气孔导度(Gs)、胞间CO_(2)浓度(Ci)等光合指标较对照均减小。根据测定的指标通过主成分分析等对其耐涝性进行评价,结果表明,淹水胁迫导致植物根系发褐、腐烂;植株出现萎蔫、落叶甚至死亡;随着淹水时间的增加,6种花灌木出现不同程度的光合系统受损。主成分分析结果表明,淹水胁迫主要影响植物的根系,进一步影响植物光和系统,最终评价得出6种花灌木的耐涝性排序为欧洲荚蒾>金钟花>小花溲疏>水栒子>圆锥绣球>重瓣榆叶梅。

关键词：淹水胁迫根系变化形态特征光合特性叶绿素荧光特性花灌木

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Research on perception of juncturebetween syllables in Chinese

引用

Chinese Journal of Acoustics 1998年第2期17卷 143-152页

作者： CHU Min TANG Difei si hongyan TIAN Xuqing LU Shinan (Institute of Acoustics, Academia sinica Beijing 100080) KONG Jiangping (The Institute of Nationality Studies, CASS Beijing 100081)

For Chinese synthesis systems that use syllables as basic units, the perception of between-syllable juncture is a matter of interest. In this paper, a two-step perception test to investigate the perception property of formani transition is presented. The first step is a set of exploring tests, from which it is found that subjects can not distinguish whether the formants of two successive syllables are transited smoothly. The second step perception test is disigned to investigate the perception of formant transitions on a more thorough environment. The stimuli of the test are disyllabic words, which cover various phonemic structures and tonal combinations. Both the average person and specialists on phonetics and speech technology are invested to be subjects. Results of the second step test are consistent with those of the flrst step. The results also show that listeners are in general not sensitive to formant ***, both segment structure and tonal variation will affect the perception of formant *** listeners with phonology knowledge tend to pay more attention to formant transition than others, they still have difficulty to distinguish synthetic disyllabic words with formant transition between syllables from those without

关键词： IR Research on perception of juncturebetween syllables in Chinese

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

应用化学专业实验与相关理论课程整体优化的探索

引用

山东化工 2018年第10期47卷 163-164,167页

作者：司红岩向天成许昌学院化学化工学院河南许昌461000

对应用化学专业实验及相关理论课程整体优化的必要性及可行性进行了探讨。在对课程的知识体系进行分解和整合基础上,重新优化教学内容,并以实际生产中的项目为载体,进行项目教学的探索与实践。

关键词：应用化学专业实验理论课整体优化

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dynamic Response of Tension Plate for UHVDC Transmission Lines Under Ice Shedding Loads

引用

CSEE Journal of Power and Energy Systems 2022年第3期8卷 952-962页

作者： Jiajun si Lixian Zhou Kuanjun Zhu hongyan Zhao Bin Liu Xiaoming Rui Shengchun Liu China Electric Power Research Institute Beijing 100192China North China Electric Power University Beijing 102206China Beijing Institute of Astronautical Systems Engineering Beijing 100075China Electric Power Research Institute Beijing 100192China

Ice shedding problems have severely threatened the safety of overhead transmission lines and caused enormous ruptures or failures of the conductors and their *** is of great importance to study the dynamic properties of the transmission lines under ice shedding *** perform such analysis,the dynamic behavior of two typical strain sections for UHVDC transmission lines under different ice shedding conditions were simulated in this ***,the dynamic response of the key tension plate as well as its buckling properties was analyzed based on the extacted ice shedding ***,laboratory tests were conducted at the China Electric Power Research Institute to assess the critical value of the buckling of the tension *** results show that the key tension plate studied in this paper is primarily influenced by the loads along the transmission lines after taking its dynamic response and buckling properties under synthetic ice shedding conditions into *** short-term fluctuation of the tension should be the major focus in tension plate designs.

关键词： Dynamic response ice shedding effect nonlinear buckling tension plate UHVDC transmission lines

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：