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Interaction and Relationship Between Angiotensin ConvertingEnzyme Gene and Environmental Factors Predisposing toEssential Hypertension in MongolianPopulation of China

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Biomedical and Environmental Sciences 2004年第2期17卷 177-186页

作者： QUNXU YAN-HUAWANG WEI-JUNTONG MING-LIANGGU GANGWU BATUBUREN YONG-YUELIU JIANWANG YONG-SHANLI HUAFENG shuang-lianbai HAI-HUAPANG GUI-RONGHUANG MING-WUFANG YONG-HONGZHANG ZHENG-LAIWU CHANG-CHUNQIU NationalLaboratoryofMedicalMolecularBiology SchoolofBasicMedicinePekingCollegeInstituteofBasicMedicalSciencesChineseAcademyofMedicalSciencesBeijing100005China DepartmentofEpidemiology SchoolofBasicMedicinePekingUnionMedicalCollegeInstituteofBasicMedicalSciencesChineseAcademyofMedicalSciencesBeijing100005China DepartmentofEpidemiology PublicHealthSchoolHarbinMedicalUniversityHarbin150001HeilongjiangChina CenterforDiseaseControlandPreventionofTongliao Tongliao028000InnerMongoliaChina CenterHospitalofTongliao Tongliao028000InnerMongoliaChina CenterforDiseaseControlandPreventionofKezuohouqi Kezuohouqi028100InnerMongoliaChina

Objective To investigate the association of specific functional gene ACE (I/D) variants of the renin-angiotensin system with essential hypertension (EH) and interaction between ACE (I/D) gene and risk factors for EH in a genetically homogenous Mongolia rural population of China. Methods Individuals (n=1099) were recruited from general population of Kezuohouqi Banner in Inner Mongolian Autonomous Region. Results The association was found between ACE genotype DD plus ID and EH, with an interaction between ACE genotype DD plus ID and cigarette smoking in an additive model. Cigarette smoking index and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 7.10 to 1.16. Interaction between ACE genotype DD plus ID and alcohol drinking on EH appeared an additive model. Alcohol drinking index and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 1.66 to 1.09. BMI and ACE gene showed a low exposure-gene (LEG) effect on EH, with interaction indices from 6.15 to 2.49. Interactions between ACE genotype and WHR on EH showed a multiplicative model. In a short, there was an interaction between ACE gene and cigarette smoking, alcohol drinking and BMI on EH, especially in a low dose-exposure effect Conclusion It is important for individuals who carry ACE D allele gene to prevent EH, and furthermore, to prevent and control coronary heart disease, in a view of population-based prevention.

关键词： Angiotensin-converting enzyme Hypertension Genetic Risk factors Interaction Exposure-gene effect

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Engineering atomic Rb-N configurations to tune radical pathways for highly selective photocatalytic H2O2 synthesis coupled with biomass valorization

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Journal of Energy Chemistry 2025年第1期100卷 215-225页

作者： Jiaye Li shuang Pan Yihuang Chen Qiong Liu College of Chemistry and Materials Engineering Wenzhou University Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology (China) Institute of Analysis Guangdong Academy of Sciences (China National Analytical CenterGuangzhou)

Photocatalytic oxygen reduction for hydrogen peroxide （H2O2） synthesis presents a green and costeffective production ***,achieving highly selective H2O2synthesis remains challenging,necessitating precise control over free radical reaction pathways and minimizing undesirable oxidative ***,we report for the visible light-driven simultaneous co-photocatalytic reduction of O2to H2O2and oxidation of biomass using the atomic rubidium-nitride modified carbon nitride（CNRb）.The optimized CNRb catalyst demonstrates a record photoreduction rate of 8.01 mM h-1for H2O2generation and photooxidation rate of 3.75 mM h-1for furfuryl alcohol to furoic acid,achieving a remarkable solar-to-chemical conversion （SCC） efficiency of up to 2.27%.Experimental characterizations and DFT calculation disclosed that the introducing atomic Rb–N configurations allows for the high-selective generation of superoxide radicals while suppressing hydroxyl free radical *** is because the Rb–N serves as the new alternative site to perceive a stronger connection position for O2adsorption and reinforce the capability to extract protons,thereby triggering a high selective redox product *** study holds great potential in precisely regulating reactive radical processes at the atomic level,thereby paving the way for efficient synthesis of H2O2coupled with biomass valorization.

关键词： Atomic economy Radical pathway regulation Rubidium atom coordination Biomass valorization

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Synergistically enhanced ORR and HER performance on Co-N-C coupled in-situ generated PtCo intermetallic

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Journal of Energy Chemistry 2025年第1期100卷 721-729页

作者： Guanyu Luo Min Song Lulu An Xiao Huang Qian Zhang Chenhao Zhang Tao Shen shuang Wang Deli Wang Key Laboratory of Material Chemistry for Energy Conversion and Storage (Huazhong University of Science and Technology) Ministry of Education School of Chemistry and Chemical Engineering Huazhong University of Science and Technology

Integrating multi-scale sites in a composite catalyst is vital to realize efficient ***,a synergistic composite catalyst consisting of Co atomic sites and in-situ generated PtCo intermetallic compounds （IMCs）(o-PtCo@CoNC) is proposed through Co pre-anchoring and subsequent impregnation-reduction *** loading of Co atoms provides a chance for in-situ generating PtCo ordered intermetallic *** remaining Co single atoms and PtCo IMCs construct synergistic electrocatalytic *** from the ordered structure,synergistic effect of Pt Co IMCs and Co single atoms,o-PtCo@CoNC exhibits excellent electrocatalytic performance for oxygen reduction reaction （ORR） and hydrogen evolution reaction （HER） with mass activity of 1.21 A mgPt-1（at 0.9 V） and5.70 A mgPt-1（at an overpotential of 100 mV）,***,o-PtCo@CoNC delivers negligible loss of half-wave potential and overpotential during long-term stability test in acid solutions,with 13 mV decay after 50,000 potential cycles for ORR and a 2.7 mV decay after 20,000 potential cycles for *** integration strategy of single-atomic sites coupled IMCs paves the way for enhancing the activity and durability of Pt-based electrocatalysts.

关键词： Electrolytic reduction

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新质生产力、科技金融发展与投融资体制变革

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新疆师范大学学报（哲学社会科学版） 2025年第2期46卷 30-38,F0002页

作者：王曙光梁爽北京大学经济学院北京100871 北京大学产业与文化研究所北京100871

培育新质生产力需要形成与之相适应的新型生产关系,深化金融体制改革,形成与科技创新相适应的科技金融体系尤为关键。当前,中国科技金融发展面临诸多挑战,存在金融资源分配不均、耐心资本短缺、金融服务创新不足等问题。要充分发挥我国... 详细信息

培育新质生产力需要形成与之相适应的新型生产关系,深化金融体制改革,形成与科技创新相适应的科技金融体系尤为关键。当前,中国科技金融发展面临诸多挑战,存在金融资源分配不均、耐心资本短缺、金融服务创新不足等问题。要充分发挥我国社会主义制度优势,寻找政府引导、市场运作与科技型企业创新之间的最佳契合点,以壮大耐心资本为核心,服务初创期及中小规模科技型企业为重点,依托新型举国体制和社会主义市场经济体制,深化科技型企业的投融资体制变革。未来,要着力构建“股贷债保”联动、覆盖全生命周期、全链条、接力式的科技金融体系,为发展新质生产力提供坚实的金融支撑。

关键词：新质生产力科技金融投融资体制耐心资本新型举国体制

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初中生认知控制对替代性攻击行为的影响:激惹和触发的情境边界条件

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心理学报 2025年第1期57卷 36-57页

作者：林爽程塨渌刘文白学军天津师范大学心理学部天津300387 辽宁师范大学心理学院大连116029 广西师范大学教育学部桂林541004

本研究通过3个实验探索了初中生认知控制对替代性攻击行为的影响以及认知控制影响替代性攻击行为的激惹和触发情境边界条件。实验1考察了一般性认知控制对替代性攻击行为的影响,结果发现一般性认知控制不能有效降低替代性攻击行为的攻... 详细信息

本研究通过3个实验探索了初中生认知控制对替代性攻击行为的影响以及认知控制影响替代性攻击行为的激惹和触发情境边界条件。实验1考察了一般性认知控制对替代性攻击行为的影响,结果发现一般性认知控制不能有效降低替代性攻击行为的攻击比例。实验2探讨了特异性认知控制对替代性攻击行为的有效抑制作用,结果发现无论在高激惹情境还是低激惹情境,主动控制和反应性控制启动条件下的替代性攻击行为均显著低于基线水平。实验3则探究了特异性认知控制抑制替代性攻击行为的激惹和触发情境边界条件,结果发现特异性认知控制、激惹情境、触发情境三者的交互作用显著,激惹和触发情境能够有效调节特异性认知控制对替代性攻击行为的影响。而且,在高激惹高触发和高激惹低触发情境下,主动性控制减基线的攻击比例显著高于反应性控制减基线,但在低激惹高触发和低激惹低触发情境下主动性控制减基线的攻击比例与反应性控制减基线不存在显著差异。此外,高激惹高触发情境下主动性控制减基线的攻击比例是所有条件下最高的。以上结果说明,特异性认知控制能够有效抑制初中生的替代性攻击行为,其中主动性控制的情境边界出现在高激惹高触发情境。

关键词：认知控制替代性攻击行为激惹情境触发情境情境边界条件

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Protective effect of Weikang decoction and partial ingredients on model rat with gastric mucosa ulcer

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World Journal of Gastroenterology 2005年第8期11卷 1204-1209页

作者： Tuo-YingFan Qing-QingFeng Chun-RongJia QunFan Chun-AnLi Xue-lianbai 94HospitalofPLA Nanchang330002JiangxiProvinceChina People'sHospitalofWuhanUniversity Wuhan430060HubeiProvinceChina ShenzhenDonghuHospital Shenzhen518020GuangdongProvinceChina

AIM: To investigate the protective mechanisms of Weikang (WK) decoction on gastric mucosae. METHODS: Ninety rats were randomly divided into nine groups of 10 each, namely group, model group, group with large WK dosage, group with medium WK dosage, group with small WK dosage, group with herbs of jianpiyiqi (strengthening the spleen and replenishing qi), group with herbs of yangxuehuoxue (invigorating the circulation of and nourishing the blood), group with herbs of qingrejiedu (clearing away the heat-evils and toxic materials), group with colloidal bismuth pectin (CBP) capsules. According to the method adopted by Yang Xuesong, except normal control group, chronic gastric ulcer was induced with 100% acetic acid. On the sixth day after moldmaking, WK decoction was administered, respectively at doses of 20, 10 and 5 g/kg to rats of the WK groups, or the groups with herbs of jianpiyiqi, yangxuehuoxue and qingrejiedu, 10 ml/kg was separately administered to each group every day. For the group with CBP capsules, medicine was dissolved with water and doses 15 times of human therapeutic dose were administered (10 mL/kg solution containing 0.35% CBP). Rats of other groups were fed with physiological saline (10 ml/kg every day). Administration lasted for 16 d. Rats were killed on d 22 after mold making to observe changes of gastric mucosa. The mucus thickness of gastric mucosa surface was measured. Levels of epidermal growth factor (EGF) in gastric juice, nitric oxide (NO) in gastric tissue, endothelin (ET) in plasma, superoxide dismutase (SOD) in plasma, malondialdehyde (MDA) in plasma and prostaglandin I2 (PGI2) were examined. RESULTS: Compared with control group, ulceration was found in gastric mucosa of model group rats. The mucus thickness of gastric mucosa surface, the levels of EGF, NO, 6-K-PGF1α and SOD decreased significantly in the model group (EGF: 0.818±0.18 vs 2.168±0.375, NO: 0.213±0.049 vs 0.601±0.081, 6-K-PGF1α 59.7±6.3 vs 96.6±8.30, SOD: 128.6±15.0 vs 196.6±35

关键词： Gastric mucosa/drug effects Gastric ulcer Epidermal growth factor Nitric oxide

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Partially-Observed Maximum Principle for Backward Stochastic Differential Delay Equations

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1524-1526页

作者： shuang Wu Department of Applied Mathematics China University of PetroleumQingdao 266580China

Dear Editor,This letter investigates a partially-observed optimal control problem for backward stochastic differential delay equations(BSDDEs).By utilizing Girsanov’s theory and convex variational method,we obtain a maximum principle on the assumption that the state equation contains time delay and the control domain is *** adjoint processes can be represented as the solutions of certain time-advanced stochastic differential equations in finite-dimensional *** backward stochastic differential equation(BSDE)was first introduced by Bismut in[1],while general BSDE was given by Pardoux and Peng[2].Since then,the theory of BSDEs developed *** corresponding optimal control problems,whose states are driven by BSDEs,have also been widely studied by some authors,see[3]-[5].

关键词： stochastic backward convex

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Intelligent metasurfaces:digitalized,programmable,and intelligent platforms

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Light(Science & Applications) 2022年第9期11卷 1958-1959页

作者： shuang Zhang Department of Physics University of Hong KongHong Kong 999077China Department of Electrical and Electronic Engineering University of Hong KongHong Kong 999077China

Distinguished from conventional ones,intelligent metasurfaces are endowed with three important characteristics:digitalization,programmability,and intelligence,which can be further integrated with detection,artificial neural networks,and feedback systems into a smart ***-based smart systems are expected to play an important role in wireless communications,advanced sensing technologies and artificial intelligence.

关键词： smart artificial wireless

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基于耦合映像格子的明文关联图像加密方案

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聊城大学学报（自然科学版） 2025年第1期38卷 14-22页

作者：张爽李震贵阳人文科技学院大数据与信息工程学院贵州贵阳550025 贵州大学大数据与信息工程学院贵州贵阳550025

明文敏感性是图像加密系统重要的性能指标,用来评估加密系统抵抗差分攻击能力,而明文关联是提高明文敏感性的主要手段。针对明文关联问题,提出一种基于耦合映像格子(CML)的明文关联图像加密方案。该方案首先构建明文关联内部密钥生成模... 详细信息

明文敏感性是图像加密系统重要的性能指标,用来评估加密系统抵抗差分攻击能力,而明文关联是提高明文敏感性的主要手段。针对明文关联问题,提出一种基于耦合映像格子(CML)的明文关联图像加密方案。该方案首先构建明文关联内部密钥生成模型生成明文关联密钥流,然后在密钥流控制下完成加密操作。加密算法首先采用一轮Zigzag置乱和XOR掩码,然后进行Zigzag-CBC扩散,最后再进行一轮Zigzag置乱和XOR掩码输出密文图像。随后采用直方图、相关性分析、差分攻击、信息熵等方法对密码系统进行安全性能分析,实验结果表明,基于耦合映像格子的明文关联图像加密方案具有良好的安全性能,可以满足绝大多数应用场景下的图像加密需求。

关键词：图像加密安全性分析耦合映像格子

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Conformation and Counterion Distribution of Polyelectrolyte in Solution as Viewed from Dielectric Approach

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Chinese Journal of Polymer Science 2024年第9期42卷 1278-1301,I0005页

作者： Kong-shuang Zhao College of Chemistry Beijing Normal UniversityBeijing 100875China

Polyelectrolyte solutions are more variable than uncharged macromolecule due to electrical interaction between charged molecules and surrounding ***,the subject of polyelectrolyte solutions has attracted a wide range of interests in both basic and applied research,and has also been extensively ***,the understanding of the molecular dynamics and conformation of polyelectrolytes in solution remains to be deepened,and universal consensus on some key issues have not been *** methods have contributed to solving the above problems in different ways,including dielectric relaxation spectroscopy(DRS).In this perspective,we briefly reviewed the history of dielectric spectroscopic research on polyelectrolyte solution,with emphasis on summarizing our *** particular,we expound the characteristics of DRS and its ability to obtain the internal information of the system of ***,we evaluate the advantages and limitations of the dielectric method and discussed future prospects of this field.

关键词： Polyelectrolyte Dielectric relaxation spectroscopy Chain conformation Thermosensitive microgel PNIPAM microgel Spherical polyelectrolyte brushes

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