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Characteristics and failure mechanism of an ancient earthquake-induced landslide with an extremely wide distribution area

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Journal of Mountain Science 2018年第2期15卷 380-393页

作者： HUANG Chao LI Yu-sheng yi shu-jian LIU Kai WU Chun-hao State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of Technology Chengdu 610059 China Key Laboratory of Mountain Hazards and Surface Process Institute of Mountain Hazards and Environment Chinese Academy of Sciences Chengdu 610044 China University of Chinese Academy of Science Beijing 100049 China

The Lamuajue landslide is located in Lamuajue village on the tight bank of the Meigu River, Sichuan Province, China. This landslide is an ancient landslide with an extremely wide distribution area, covering an area of 19 km2 with a maximum width of 5-5 km and an estimated residual volume of 3 × 108 ma. The objectives of this study were to identify the characteristics and failure mechanism of this landslide. In this study, based on field investigations, aerial photography, and profile surveys, the boundary, lithology, structure of the strata, and characteristics of the landslide deposits were determined. A gently angled weak interlayer consisting of shale was the main factor contributing to the occurrence of the Lamuajue landslide. The deposition area can be divided into three zones： zone A is an avalanche deposition area mainly composed of blocks, fragments, and debris with diameters ranging from o.i m to 3 m; zone B is a residual integrated rock mass deposition area with large blocks, boulders and ＂fake bedrock＂; and zone C is a deposition zone of limestone blocks and fragments. Three types of failure mechanism were analyzed and combined to explain the Lamuajue landslide based on the features of the accumulation area. First, a shattering-sliding mechanism caused by earthquakes in zone A. Second, a sliding mechanism along the weak intercalation caused by gravity and water in zone B. Third, a shattering-ejection mechanism generated by earthquakes in zone C. The results provide a distinctive case for the study of gigantic landslides induced by earthquakes, which is very important for understanding and assessing ancient earthquakeinduced landslides.

关键词： Earthquake-induced landslide Lamuajue landslide Ancient landslide Geologicalfeature Failure mechanism

A Semiparametric Additive-multiplicative Rates Model for the Weighted Composite Endpoint of Recurrent and Terminal Events

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Acta Mathematica Sinica,English Series 2024年第4期40卷 985-999页

作者： yi DENG Qiang XIONG shu Wei LI School of Economics and Statistics Guangzhou UniversityGuangzhou 510006P.R.China

Recurrent event data are commonly encountered in many scientific fields,including biomedical studies,clinical trials and epidemiological surveys,and many statistical methods have been proposed for their *** this paper,we consider to use a weighted composite endpoint of recurrent and terminal events,which is weighted by the severity of each event,to assess the overall effects of covariates on the two types of events.A flexible additive-multiplicative model incorporating both multiplicative and additive effects on the rate function is proposed to analyze such weighted composite event process,and more importantly,the dependence structure among the recurrent and terminal events is left *** the estimation,we construct the unbiased estimating equations by virtue of the inverse probability weighting technique,and the resulting estimators are shown to be consistent and asymptotically normal under some mild regularity *** evaluate the finite-sample performance of the proposed method via simulation studies and apply the proposed method to a set of real data arising from a bladder cancer study.

关键词： Additive-multiplicative rates model estimating equation recurrent events terminal event weighted composite endpoint

马铃薯早疫病病原菌分离鉴定及不同植物提取物、茵陈二炔酮抑菌活性研究

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西南农业学报 2024年第4期37卷 714-721页

作者：廖仕梅俞舒谊杨态娇罗建梅李青闫晓慧西南林业大学生物多样性保护学院/云南省高校森林灾害预警与控制重点实验室昆明650224

[目的]明确曲靖市会泽县马铃薯早疫病的病原菌,并探究不同植物提取物和茵陈二炔酮对病原菌的抑菌活性,为马铃薯早疫病的生物防治提供科学依据。[方法]采用组织分离法分离纯化病原菌,通过形态学和分子生物学方法鉴定病原菌,利用菌丝生长... 详细信息

[目的]明确曲靖市会泽县马铃薯早疫病的病原菌,并探究不同植物提取物和茵陈二炔酮对病原菌的抑菌活性,为马铃薯早疫病的生物防治提供科学依据。[方法]采用组织分离法分离纯化病原菌,通过形态学和分子生物学方法鉴定病原菌,利用菌丝生长速率法筛选对病原菌有抑制效果的植物提取物,同时测定茵陈二炔酮抑菌毒力以及对菌丝形态、干重、还原糖、总蛋白含量的影响。[结果]曲靖市会泽县马铃薯病叶分离纯化的病原菌经鉴定为交链格孢菌(Alternaria alternata)。12种植物提取物(1 mg/mL)中椴叶鼠尾草和紫茎泽兰提取物的抑菌效果最好,抑菌率分别为55.19%和40.76%。茵陈二炔酮抑菌效果随着浓度升高而增强,经毒力测定其EC_(50)在16.418~46.576μg/mL。茵陈二炔酮使菌丝形态发生细微变化,干重显著减轻,还原糖、总蛋白含量显著降低。[结论]曲靖市会泽县马铃薯早疫病病原菌为交链格孢菌,椴叶鼠尾草和紫茎泽兰提取物对交链格孢菌有良好的抑菌效果,茵陈二炔酮通过阻碍菌丝细胞物质合成与能量代谢,影响菌丝正常生长以达到较好的抑菌效果。

关键词：马铃薯早疫病病原菌鉴定植物提取物茵陈二炔酮抑菌活性

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不同辣椒品种对细菌性斑点病抗病性鉴定与分析

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辽宁农业科学 2024年第4期 78-80页

作者：李柏宏刘丽于舒怡关天舒邹春蕾王辉辽宁省农业科学院植物保护研究所辽宁沈阳110161 辽宁省农业科学院蔬菜研究所辽宁沈阳110161

近年辽宁大型育苗企业辣椒细菌性斑点病发生严重,为有效利用辣椒抗病优质品种,试验采用人工接种的方法在辣椒8片真叶期对30份辽宁主栽辣椒品种进行室内抗病性鉴定工作。研究结果表明:神禾8819与韩国红峰平均病指13.92与14.42,为抗病品种... 详细信息

近年辽宁大型育苗企业辣椒细菌性斑点病发生严重,为有效利用辣椒抗病优质品种,试验采用人工接种的方法在辣椒8片真叶期对30份辽宁主栽辣椒品种进行室内抗病性鉴定工作。研究结果表明:神禾8819与韩国红峰平均病指13.92与14.42,为抗病品种(R);万金早椒与新品线椒玉平均病指17.17与15.25,为中抗品种(MR),4个品种均为线椒。其余3个甜椒、3个羊角椒、9个牛角椒、4个麻辣椒,7个螺丝椒平均病指在30.1~40.0,均为感病品种(S)。研究结果可为我省辣椒生产优选抗病品种与品种推广提供依据。

关键词：辣椒细菌性斑点病抗病性鉴定

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Prognostic factors for late mortality after liver transplantation for benign end-stage liver disease

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Chinese Medical Journal 2011年第24期124卷 4229-4235页

作者： ZHANG ying-cai ZHANG Qi LI Hua ZHANG Jian WANG Gen-shu XU Chi yi shu-hong yi Hui-min CAI Chang-jie LU Min-qiang YANG Yang CHEN Gui-hua Liver Transplantation Center Third Affiliated Hospital of SunYat-sen University Guangzhou Guangdong 510630 China Guangdong Provincial Key Laboratory of Liver Disease Guangzhou Guangdong 510630 China

Background There are increasing numbers of patients who survive more than one year after liver transplantation. Many studies have focused on the early mortality of these patients. However, the factors affecting long-term survival are not fully understood. This study aims to evaluate prognostic factors predicting long-term survival and to explore measures for improving the survival outcomes of patients who underwent liver transplantation for benign end-stage liver diseases. Methods The causes of late death after liver transplantation and potential prognostic factors were retrospectively analyzed for 221 consecutive patients who underwent liver transplantation from October 2003 to June 2008. Twenty-seven variables were assessed using the Kaplan-Meier method, and those variables found to be univariately significant at P〈0.10 were entered into a backward step-down Cox proportional hazard regression analysis to identify the independent prognostic factors influencing the recipients＇ long-term survival. Results Twenty-eight recipients died one year after liver transplantation. The major causes of late mortality were infectious complications, biliary complications, and Hepatitis B virus recurrence/reinfection. After Cox analysis, the five remaining co-variables were： age, ABO blood group, cold ischemia time, post-infection region, and biliary complications. Conclusions The major causes of late mortality were infection, biliary complications and Hepatitis B virus recurrence/reinfection. Five variables （Age, ABO blood group, cold ischemia time, infection, and biliary complications） had significant impacts on patient survival.

关键词： liver transplantation survival benign cause prognostic factor

谷胱甘肽促进Emericella sp. 1454中emestrin的产量提高

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药学学报 2024年第4期59卷 1087-1091页

作者：陈渝川肖同美苏冰洁闫璧滢余利岩司书毅陈明华中国医学科学院、北京协和医学院医药生物技术研究所北京100050

基于Emericella sp.1454的基因组信息,结合文献分析其次级代谢产物emestrin的生物合成前体,并通过在培养基中添加前体的方法,提高emestrin产量。本研究首次发现在培养基中添加emestrin的生物合成前体—还原型谷胱甘肽可显著提高其产量。... 详细信息

基于Emericella sp.1454的基因组信息,结合文献分析其次级代谢产物emestrin的生物合成前体,并通过在培养基中添加前体的方法,提高emestrin产量。本研究首次发现在培养基中添加emestrin的生物合成前体—还原型谷胱甘肽可显著提高其产量。每50 g大米培养基中加入1.5 g还原型谷胱甘肽,培养15天,可以得到30.82 mg的emestrin,相较于原始发酵培养方案提升了11.71倍。该方法既简单经济又高效,为后续高效制备emestrin类化合物奠定了坚实的基础,以及为其他类多硫代二酮哌嗪类化合物的产量提升提供了重要的借鉴。

关键词：前体物质谷胱甘肽 emestrin 产量提高培养基优化 Emericella sp 多硫代二酮哌嗪

Modeling the carbon dynamics of alpine grassland in the Qinghai-TibetanPlateau under scenarios of 1.5 and 2 ℃ global warming

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Advances in Climate Change Research 2019年第2期10卷 80-91页

作者： yi shu-Hua XIANG Bo MENG Bao-Ping WU Xiao-Dong DING Yong-Jian Instiute o f Fragile Ecosystem and Environment Nantong University Nantong 226007 China of Geographic Sciences Nantong University Nantong 226007 China State Key Laboratory of Cryospheric Science Northwest Institute of Eco-Environment and Resources Chinese Academy of Sciences Lanzhou 730000 China Chongqing Climate Center Chongqing 401147 China Cryosphere Research Station on the Qinghai-Tibetan Plateau Lanzhou 730000 China Key Laboratory of Ecohydrology of Inland River Basin Chinese Academy of Sciences Lanzhou 730000 China University of Chinese Academy Sciences Beijing 100049 China

Alpine grassland occupies two-thirds of the Qinghai-Tibetan Plateau (QTP). It is vital to project changes of this vulnerable ecosystem under different climate change scenarios before taking any mitigation or adaptation measures. In this study, we used a process-based ecosystem model, driven with output from global circulation models under different Representative Concentration Pathways (RCPs), to project the carbon dynamics of alpine grassland. The results showed the following: 1) Vegetation carbon (C) on the QTP increased by 22—38 gC m^-2 during periods of 1.5 and 2 ℃ warming under different RCPs when compared to the baseline period (1981—2006), while soil C increased by 85—122 gC m^-2. 2) The increases of vegetation C and soil C at the period of 1.5 ℃ warming were about 15 gC m^-2 and 40 gC m^-2 smaller than those at the period of 2 ℃ warming, respectively;increase of C was greater for alpine meadow than for alpine steppe. 3) Precipitation, radiation, and permafrost changed significantly and showed heterogeneous spatial patterns, and caused heterogeneous response of C dynamics. For alpine meadow in regions transformed from permafrost to seasonally frozen soil with medium annual precipitation (200—400 mm), vegetation C and net primary production decreased by 18.7 gC m-2 and 3.1 gC m^-2 per year during 2 °C warming under RCP 4.5, respectively. This decrease can be attributed to the disappearing impermeable permafrost. Different from previous studies that indicated an unfavorable response of alpine grassland to climate warming, this study showed a relatively favorable response, which is mainly attributed to C 0 2 fertilization.

关键词： Permafrost Terrestrial ecosystem model Vegetation Soil Net primary production

立新七针三联针法联合牵引治疗腰椎间盘突出症临床观察

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山西中医 2024年第7期40卷 32-34页

作者：陈震刘舒怡张文福王同亮甘肃省酒泉市中医医院酒泉735000

目的:观察立新七针三联针法联合牵引治疗腰椎间盘突出症的临床疗效。方法:选取符合纳入标准的腰椎间盘突出症患者60例,按随机数字表法分为两组各30例。对照组予常规针刺及腰椎牵引治疗,治疗组予立新七针三联针法及腰椎牵引治疗。2周为1... 详细信息

目的:观察立新七针三联针法联合牵引治疗腰椎间盘突出症的临床疗效。方法:选取符合纳入标准的腰椎间盘突出症患者60例,按随机数字表法分为两组各30例。对照组予常规针刺及腰椎牵引治疗,治疗组予立新七针三联针法及腰椎牵引治疗。2周为1个疗程,每个疗程间隔3天,共治疗3个疗程。比较两组患者治疗前后疼痛视觉模拟评分(VAS)、日本骨科协会评估治疗分数(JOA)评分。结果:治疗组总有效率为93.33%,优于对照组的70.00%(P﹤0.05)。治疗后,两组患者VAS评分较治疗前均明显升高(P﹤0.05),JOA评分较治疗前均明显下降(P﹤0.05),且治疗组的VAS评分及JOA评分改善程度均优于对照组(P﹤0.05)。结论:立新七针三联针法联合牵引治疗腰椎间盘突出患者疗效确切,能明显改善腰椎功能。

关键词：腰椎间盘突出症立新七针三联针法针灸疗法

Self-assembly of surfactant-like peptides and their applications

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Science China Chemistry 2014年第12期57卷 1634-1645页

作者： ZHANG Jing Hui ZHAO Yu Rong HAN shu yi CHEN Cui Xia XU Hai Centre for Bioengineering and Biotechnology China University of Petroleum (East China)

Numerous peptides derived from naturally occurring proteins or de novo designed have been found to self-assemble into various *** well-defined nanostructures have shown great potential for a variety of biomedical and biotechnological *** particular,surfactant-like peptides(SLPs)have distinctive advantages in their length,aggregating ability,and water *** this article,we report recent advances in the mechanistic understanding of the self-assembly principles of SLPs and in their applications,most of which have been made in our *** bonding between peptide backbones,hydrophobic interaction between hydrophobic side chains,and electrostatic repulsion between charged head groups all have roles in mediating the self-assembly of SLPs;the final self-assembled nanostructures are therefore dependent on their *** have shown diverse applications ranging from membrane protein stabilization and antimicrobial/anticancer agents to nanofabrication and *** advances in the self-assembly of SLPs will hinge on their large-scale production,the design of new functional SLPs with targeted properties,and the exploitation of new or improved applications.

关键词： surfactant-like peptides self-assembly mechanism applications