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Wangbi capsule for active rheumatoid arthritis:a multicenter,randomized,double-blind,parallel-controlled study

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China Medical Abstracts(Internal Medicine) 2024年第2期41卷 80-81页

作者：吴金联 Dept Rheumatol&Immunol Longhua HospShanghai TCM UnivShanghai 200032

Objective To evaluate the efficacy and safety of Wangbi Capsule(WBC)in the treatment of active rheumatoid arthritis(RA).Methods Totally 101 patients in line with inclusion criteria from 114 patients with active RA were assigned to the treatment group(52 cases)and the control group(49 cases)by using block randomization method,which was stratified by center with a selected segment length of 2 and the PROC PLAN procedure statement in SAS9.4 Software used to give the number of *** in the treatment group took WBC+methotrexate(MTX),while those in the control group took WBC placebo+*** treatment course lasted for 12 *** comparing the 28 joint disease activity scores(DAS28-ESR)based1onerythrocyte sedimentation rate(ESR),28 joint disease activity scores(DAS28-CRP)based onC-reactive protein(CRP),DAS28-ESR remission rate,DAS28-CRP remission rate,ESR,CRP,rheumatoid factor(RF),and anti-cyclic citrulline antibody(ACPA)before and after treatment,patient visual analogue score(VAS),physician VAS score,joint pain count,joint swelling count.

关键词： rheumatoid capsule treatment

1990~2019年中国男性泌尿与生殖系统肿瘤疾病负担变化及预测分析

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中华男科学杂志 2024年第5期30卷 397-403页

作者：受梦媛郑楠刘一笑吴小玉方柔柔孙娜陕西中医药大学公共卫生学院陕西咸阳712046

目的:分析及预测1990~2019年中国男性泌尿及生殖系统肿瘤中前列腺癌、睾丸癌、肾癌和膀胱癌的疾病负担变化。方法:全球疾病负担数据库中选择1990~2019年中国男性前列腺癌、睾丸癌、肾癌和膀胱癌的发病、死亡与疾病负担数据,运用Joinpoin... 详细信息

目的:分析及预测1990~2019年中国男性泌尿及生殖系统肿瘤中前列腺癌、睾丸癌、肾癌和膀胱癌的疾病负担变化。方法:全球疾病负担数据库中选择1990~2019年中国男性前列腺癌、睾丸癌、肾癌和膀胱癌的发病、死亡与疾病负担数据,运用Joinpoint回归模型计算疾病负担的变化趋势,ARIMA模型对发病情况进行预测。结果:1990~2019年中国男性前列腺癌、肾癌、膀胱癌、睾丸癌的标化发病率及患病率均处于上升水平,睾丸癌标化发病率和患病率增幅最高,分别增长了326.79%和1070.93%;前列腺癌疾病负担最高,2019年其标化发病率、患病率、死亡率分别为17.34/10万、117.65/10万、7.79/10万;肾癌的标化死亡率与DALY率明显上升,分别增长了103.59%和103.17%。2019年前列腺癌、肾癌和膀胱癌发病率、死亡率和DALYs率最高的年龄段均为90~94岁,患病率最高的年龄段为70~89岁;睾丸癌患病率最高的年龄段为25~49岁。ARIMA模型预测显示,2020~2029年中国男性前列腺癌、睾丸癌、肾癌和膀胱癌的标化发病率仍呈上升趋势。结论:中国男性前列腺癌、睾丸癌、肾癌、膀胱癌的疾病负担呈上升趋势,其中年轻男性该系统疾病负担上升显著,提示年轻人群泌尿生殖系统肿瘤的防治问题应进一步关注;预测到2029年,标化发病率均有所上升。

关键词：男性泌尿与生殖肿瘤疾病负担预测

Emerging probing perspective of two-dimensional materials physics:terahertz emission spectroscopy

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Light(Science & Applications) 2024年第7期13卷 1278-1298页

作者： Yifei wu Yuqi Wang Di Bao Xiaonan Deng Simian Zhang Lin Yu-chun Shengxian Ke Jianing Liu Yingjie Liu Zeli Wang Pingren Ham Andrew Hanna Jiaming Pan Xinyue Hu Zhengcao Li Ji Zhou Chen Wang State Key Laboratory of New Ceramics and Fine Processing Key Laboratory of Advanced Materials of Ministry of EducationSchool of Materials Science and EngineeringTsinghua University100084 BeijingChina Beijing Advanced Innovation Center for Integrated Circuits 100084 BeijingChina

Terahertz(THz)emission spectroscopy(TES)has emerged as a highly effective and versatile technique for investigating the photoelectric properties of diverse materials and nonlinear physical processes in the past few ***,research on two-dimensional(2D)materials has experienced substantial growth due to their atomically thin structures,exceptional mechanical and optoelectronic properties,and the potential for applications in flexible electronics,sensing,and ***,these materials offer advantages such as tunable bandgap,high carrier mobility,wideband optical absorption,and relatively short carrier *** applying TES to investigate the 2D materials,their interfaces and heterostructures,rich information about the interplay among photons,charges,phonons and spins can be unfolded,which provides fundamental understanding for future *** it is timely to review the nonlinear processes underlying THz emission in 2D materials including optical rectification,photon-drag,high-order harmonic generation and spin-to-charge conversion,showcasing the rich diversity of the TES employed to unravel the complex nature of these *** applications based on THz emissions,such as THz lasers,ultrafast imaging and biosensors,are also *** further,we analyzed the unique advantages of spintronic terahertz emitters and the future technological advancements in the development of new THz generation mechanisms leading to advanced THz sources characterized by wide bandwidth,high power and integration,suitable for industrial and commercial *** continuous advancement and integration of TES with the study of 2D materials and heterostructures promise to revolutionize research in different areas,including basic materials physics,novel optoelectronic devices,and chips for post-Moore’s era.

关键词： optoelectronic versatile exceptional

新型乳化体系及其在化妆品中的应用(Ⅴ)——Janus乳液

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日用化学工业（中英文） 2024年第1期54卷 24-31页

作者：韩旭吴槚佳武娜尚亚卓华东理工大学化学与分子工程学院化妆品研究室上海200237

Janus乳液是内相由两种互不相溶、彼此独立、界面分明的液相组成的单液滴形式的多分散体系,其内相两腔室的物质组成不同,两腔室的性质和形状具有不对称性,是一类特殊类型的各向异性乳液。Janus乳液不但保持了传统乳液的基本性质,其两腔... 详细信息

Janus乳液是内相由两种互不相溶、彼此独立、界面分明的液相组成的单液滴形式的多分散体系,其内相两腔室的物质组成不同,两腔室的性质和形状具有不对称性,是一类特殊类型的各向异性乳液。Janus乳液不但保持了传统乳液的基本性质,其两腔室、多样的界面和灵活的结构、较大的界面面积和独立的空间等独特的结构优势使其对诸多功能性物质的选择性增溶、隔离、保护以及缓释等作用优于传统乳液。Janus乳液具有结构多样、定量可调的特点,可通过改变乳化剂种类、含量及各相的比例等实现对体系内界面的种类、数量和相对面积的调整,进而调控体系性质,以满足不同的使用需求。Janus乳液在化妆品、食品、生物医药以及微反应器等领域具有潜在的应用前景。本文介绍了Janus乳液及其制备方法,总结了影响Janus乳液性质的关键因素,概况了Janus乳液的性能优势。并基于目前对Janus乳液的研究及应用现状,展望了Janus乳液在化妆品领域的应用前景,并简单介绍了另外一种新型各向异性乳液——Cerberus乳液。同时,指出了Janus乳液在化妆品中应用面临的问题,并对有必要开展的研究工作提出了个人观点,旨在为性能优异的Janus乳液的开发及其在化妆品领域的实际应用提供参考信息。

关键词： Janus乳液拓扑结构各向异性乳液化妆品

不同耕作方式与地膜覆盖对花生生理特性、产量及品质的影响

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花生学报 2024年第2期53卷 47-54,76页

作者：张伟锋吴会福王瑞杰柳玉芳郑玲山东省潍坊市农业技术推广中心山东潍坊261061 潍坊市潍城区乐埠山生态经济发展服务中心山东潍坊261021 昌乐县宝城街道农业农村综合服务中心山东昌乐262400 龙口市诸由观镇农业综合服务中心山东龙口265700 山东师范大学生命科学院山东济南250014

为优化花生栽培管理措施,进而提升花生产量和品质,本研究通过设置旋耕地膜覆盖(RTM),旋耕露地(RT),深耕地膜覆盖(DTM)以及深耕露地(DT)四个处理,系统研究了不同耕作方式和地膜覆盖对花生生理特性、产量及品质的影响。结果表明:深耕能够... 详细信息

为优化花生栽培管理措施,进而提升花生产量和品质,本研究通过设置旋耕地膜覆盖(RTM),旋耕露地(RT),深耕地膜覆盖(DTM)以及深耕露地(DT)四个处理,系统研究了不同耕作方式和地膜覆盖对花生生理特性、产量及品质的影响。结果表明:深耕能够改善花生的光合性能,与RTM处理相比,DTM处理在2021年结荚期、饱果期和收获期的叶片净光合速率平均提高了2.57%;此外,深耕有利于花生干物质积累量的增加,与RTM处理相比,DTM处理累积干物质积累量在2021年提高了3.09%。地膜覆盖可以提高花生根系活力、叶片SPAD值、叶面积指数和净光合速率,延缓植株衰老,改善籽仁品质;与DT处理相比,DTM处理在2021年结荚期、饱果期和收获期的根系活力和叶面积指数分别平均提高了11.70%和13.40%。DTM处理与RTM、DT和RT处理相比,2022年荚果产量分别显著提高了5.72%、8.27%和13.08%。综上,深耕地膜覆盖可作为实现花生高产优质生产目标的有效措施。

关键词：花生耕作方式地膜覆盖生理特性产量品质

TRACK与C-ACT评分在儿童哮喘管理中的价值评估

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重庆医科大学学报 2024年第7期49卷 865-870页

作者：蒋静李雪梅石瑾吴晓彬曾书旬周玲重庆市妇幼保健院/重庆医科大学附属妇女儿童医院儿二科重庆401147

目的:通过研究儿童呼吸和哮喘控制测试(test for respiratory and asthma control in kids,TRACK)和儿童哮喘控制测试(childhood asthma control test,C-ACT)与全球哮喘防治创议(global initiative for asthma,GINA)标准哮喘控制水平评估的一致性、与哮喘儿童肺功能指标的相关性,探讨2种评分方法在儿童哮喘管理中的价值。方法:选择2020年8月至2022年3月重庆市妇幼保健院儿科门诊就诊的哮喘患儿135例为研究对象,用TRACK评分表和C-ACT评分表对相应年龄的患儿及其家长进行问卷调查,分析2种评分方法与GINA标准哮喘控制水平评估分级的一致性、与肺功能指标的相关性,并比较不同评分结果组肺功能指标差异。结果:TRACK评分、C-ACT评分与GINA哮喘控制水平分级一致性检验Kappa值分别为0.517和0.531,均显示一致性一般;TRACK评分与TPF%TE和VPF%VE存在显著的正相关,但TRACK评分、C-ACT评分与FEV1%均没有显著性相关;不同TRACK评分组哮喘患儿的FEV1%差异无统计学意义(F=2.054,P=0.134),但多重比较发现≥80分组与<60分组FEV1%的差异有统计学意义(P=0.048);不同TRACK评分组哮喘患儿的TPTEF/TE(%)(F=3.171,P=0.044)和VPEF/VE(%)(F=3.919,P=0.022)差异有统计学意义,进一步多重比较发现其差异主要来自于≥80分组与60~80分组,其中VPEF/VE(%)(P=0.017)的组间差异较TPTEF/TE(%)(P=0.030)更为明显;比较不同C-ACT评分组哮喘患儿的FEV1%差异无统计学意义(F=1.756,P=0.182)。结论:TRACK评分能更好反映儿童肺功能的差异,可作为5岁以下儿童哮喘管理的一个有效评估工具。

关键词：儿童呼吸和哮喘控制测试儿童哮喘控制测试全球哮喘防治创议哮喘管理

Non-contact wide-field viewing system-assisted scleral buckling surgery for retinal detachment in silicone oilfilled eyes

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 761-766页

作者： Su-Lan wu Yi-Qi Chen Li-Jun Shen Jian-Bo Mao Li Lin Ji-Wei Tao Huan Chen Shi-An Zhang Jia-Feng Yu Chen-Xi Wang Center for Rehabilitation Medicine Department of OphthalmologyZhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou Medical CollegeHangzhou 310000Zhejiang ProvinceChina The Affiliated Eye Hospital of Wenzhou Medical University in Hangzhou Hangzhou 310000Zhejiang ProvinceChina

AIM:To evaluate scleral buckling(SB)surgery using a noncontact wide-field viewing system and 23-gauge intraocular illumination for the treatment of rhegmatogenous retinal detachment in silicone oil(SO)-filled ***:Totally 9 patients(9 eyes)with retinal detachment in SO-filled eyes were retrospectively *** patients underwent non-contact wide-field viewing system-assisted buckling surgery with 23-gauge intraocular *** was removed at an appropriate time based on *** patients were followed up for at least 3mo after SO *** reattachment,complications,visual acuity and intraocular pressure(IOP)before and after surgery were ***:Patients were followed up for a mean of 8.22mo(3-22mo)after SO *** patients had retinal *** the final follow-up,visual acuity showed improvement for 8 patients,and no change for 1 *** IOP was high in 3 patients before surgery,but it stabilized after treatment;it was not affected in the other *** of the patients had infections,hemorrhage,anterior ischemia,or any other ***:This new non-contact wide-field viewing system-assisted SB surgery with 23-gauge intraocular illumination is effective and safe for retinal detachment in SO-filled eyes.

关键词： non-contact wide-field viewing system scleral buckling silicone oil-filled retinal detachment

CrN supported by carbon nanosheets as efficient catalysts toward oxygen reduction reaction and Zn-air batteries

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Rare Metals 2024年第10期43卷 4973-4981页

作者： Ya-Ting Zhang Fan Zhang Zhe Lu Jun-Ming Luo Su-Yang Feng Qi Wang Hui Chen Hao-Ming wu Zheng-Pei Miao Bin Chi Neng Yu Cheng-Hang You Jing Li Xin-Long Tian School of Chemistry and Chemical Engineering School of Marine Science and EngineeringHainan Provincial Key Lab of Fine ChemistryHainan University State Power Investment Group Hainan Electric Power Co.Ltd. Key Laboratory of Fuel Cell Technology of Guangdong Province Shenzhen Automotive Research Institute Beijing Institute of Technology State Key Laboratory of Nuclear Resources and Environment East China University of Technology

Exploring non-precious efficient oxygen reduction reaction （ORR） catalysts is of great significance to fuel cells and Zn-air batteries （ZABs）.CrN is a theoretically promising ORR catalyst,but its potential needs to be unlocked by proper supports that provide high conductivity and high exposure of active *** this work,we introduce a novel synthesis of carbon nanosheets-supported CrN nanoparticles （CrN/C） by annealing the mixture of CrCl3,1,10-phenanthroline and melamine via a two-step *** prepared CrN/C materials show good ORR activity and stability in acidic and alkaline *** optimal CrN/C material has an ORR half-wave potential of 0.73 and 0.72 V （*** hydrogen electrode） in acidic and alkaline media,*** it retains 82% and 78% of ORR current density in acidic and alkaline media after durability tests,***,the optimal CrN/C material-based self-breathing ZABs deliver a maximum power density of 168 mW·cm-2,which is one of the highest among transition metal nitrides-based ZABs It is found that the ORR activity of CrN/C materials is highly related to the Cr–N valence *** work highlights the good potential of CrN as robust ORR catalyst and verifies its promising application in ZABs.

关键词： Carbon nanosheets CrN Fuel cells Oxygen reduction reaction Zn-air batteries

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金融集聚、产学研合作与新质生产力

财经理论与实践 2024年第3期45卷 27-34页

作者：任宇新吴艳伍喆湘潭大学商学院湖南湘潭411105

基于2013—2022年中国30个省(区、市)面板数据,以劳动者、劳动资料、劳动对象三个维度构建区域新质生产力评价指标体系,运用熵权-TOPSIS法测算区域新质生产力发展水平,并通过双向固定效应模型和中介效应模型分析金融集聚、产学研合作与... 详细信息

基于2013—2022年中国30个省(区、市)面板数据,以劳动者、劳动资料、劳动对象三个维度构建区域新质生产力评价指标体系,运用熵权-TOPSIS法测算区域新质生产力发展水平,并通过双向固定效应模型和中介效应模型分析金融集聚、产学研合作与新质生产力三者之间的互动关系。结果显示:金融集聚可促进新质生产力提升,且表现出区域异质性特征;产学研合作在金融集聚对新质生产力的影响过程中起到部分中介作用。基于此,应加强金融集聚建设,加快产学研合作标准化、网络化,为支持区域新质生产力发展提供决策参考。

关键词：金融集聚新质生产力产学研合作评价指标体系