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缺血预处理对缺血再灌注的大鼠肝脏中肿瘤坏死因子-α、细胞间黏附分子-1 mRNA表达的影响

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山西医科大学学报 2001年第2期32卷 128-131页

作者：徐钧王世明苏东明鲍民生李正中山西医科大学第一临床医学院普外科太原030001

目的　通过观察缺血预处理对缺血再灌注大鼠肝脏中的一些生化指标的变化 ,以及肿瘤坏死因子 α和细胞间粘附分子 1mRNA表达的变化 ,研究缺血预处理对缺血再灌注损伤的干预方式及干预程度。方法　利用大鼠肝脏缺血再灌注损伤模型 ,比... 详细信息

目的　通过观察缺血预处理对缺血再灌注大鼠肝脏中的一些生化指标的变化 ,以及肿瘤坏死因子 α和细胞间粘附分子 1mRNA表达的变化 ,研究缺血预处理对缺血再灌注损伤的干预方式及干预程度。方法　利用大鼠肝脏缺血再灌注损伤模型 ,比较缺血预处理组与缺血再灌注组以及各预处理组间在血清天冬氨酸转氨酶、丙氨酸转氨酶、乳酸脱氢酶 ,肝组织中丙二醛、过氧化物歧化酶等生化指标的含量变化 ,并观察了组织中中性粒细胞 (PMNs)浸润量 ,研究了TNF α及ICAM 1mRNA表达的变化。结果　各预处理组酶的漏出和脂质过氧化物的形成减少 ,抗氧自由基能力增强 ,组织中PMNs浸润量降低 ,TNF α和ICAM - 1mRNA表达减少。结论　缺血预处理对肝脏缺血再灌注损伤有显著的保护作用。一次缺血 10min再灌注 10min的预处理保护效果最佳。缺血预处理的干预机制可能是通过下调TNF α和ICAM 1mRNA表达 ,减轻PMNs在病变部位聚集及其所产生的病理损伤作用而实现的。

关键词：肝缺血预处理再灌注损伤肿瘤坏死因子-α 细胞间黏附分子1 mRNA

Inner Structure of Statistical Gauge Potential in Chern-Simons-Ginzburg-Landau Theory

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Communications in Theoretical Physics 2005年第3X期44卷 559-562页

作者： DUAN Yi-shi ZHANG Xiu-ming Institute of Theoretical Physics Lanzhou University Lanzhou 730000 China

Based on the decomposition theory of the U（1） gauge potential, the inner structure of the statistical gauge potential in the Chern-Simons-Ginzburg-Landau （CSGL） theory is studied. We give a new creation mechanism of the statistical gauge potential, Furthermore, making use of the b-mapping topological current theory, we obtain the precise topological expression of the statistical magnetic field, which takes the topological information of the vortices.

关键词： gauge potential decomposition theory topological quantum mechanics

The Memory Orchestra:Contribution of Astrocytes

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Neuroscience Bulletin 2023年第3期39卷 409-424页

作者： Yi-Hua Chen shi-Yang Jin Jian-ming Yang Tian-ming Gao State Key Laboratory of Organ Failure Research Key Laboratory of Mental Health of the Ministry of EducationGuangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired IntelligenceGuangdong Province Key Laboratory of Psychiatric DisordersDepartment of NeurobiologySchool of Basic Medical SciencesSouthern Medical UniversityGuangzhou 510515China

For decades,memory research has centered on the role of neurons,which do not function in ***,astrocytes play important roles in regulating neuronal recruitment and function at the local and network levels,forming the basis for information processing as well as memory formation and *** this review,we discuss the role of astrocytes in memory functions and their cellular underpinnings at multiple time *** summarize important breakthroughs and controversies in the field as well as potential avenues to further illuminate the role of astrocytes in memory processes.

关键词： Astrocytes Learning and memory GPCR Calcium signal Plasticity

Efficient Scheme for Entangling Two Distant Atoms

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Communications in Theoretical Physics 2008年第2期49卷 351-354页

作者： LU Dao-ming ZHENG shi-Biao Department of Electronic Engineering Nanping Teachers College Wuyishan 354300 China Department of Electronic Science and Applied Physics Fuzhou University Fuzhou 350002 China

A scheme is presented for the generation of entangled states for two atoms trapped in two distant cavities. In the scheme each atom is resonantly coupled with the respective cavity mode and driven by a strong classical field. The detection of a photon decaying from the cavities and passing through a beam-splitter collapses the atoms to an entangled state. The required atom-field interaction time is very short and thus the decoherence effect is suppressed. Our scheme is within the reach of presently available cavity QED techniques.

关键词： entangled state cavity QED beam splitter

Electronic and Shallow Impurity States in Semiconductor Heterostructures Under an Applied Electric Field

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Communications in Theoretical Physics 2005年第2X期44卷 375-380页

作者： ZHOU Hai-Yang GU shi-Wei shi Yao-ming Department of Physics Shanghai University Shanghai 200436 China Department of Applied Physics Shanghai Jiao Tong University Shanghai 200030 China

With the use of variational method to solve the effective mass equation, we have studied the electronic and shallow impurity states in semiconductor heterostructures under an applied electric field. The electron energy levels are calculated exactly and the impurity binding energies are calculated with the variational approach. It is found that the behaviors of electronic and shallow impurity states in heterostructures under an applied electric field are analogous to that of quantum wells. Our results show that with the increasing strength of electric field, the electron confinement energies increase, and the impurity binding energy increases also when the impurity is on the surface, while the impurity binding energy increases at first, to a peak value, then decreases to a value which is related to the impurity position when the impurity is away from the surface. In the absence of electric field, the result tends to the Levine's ground state energy (-1/4 effective Rydberg) when the impurity is on the surface, and the ground impurity binding energy tends to that in the bulk when the impurity is far away from the surface. The dependence of the impurity binding energy on the impurity position for different electric field is also discussed.

关键词： heterostructures electric field impurity states

Direct Electrochemistry Transfer and Electrocatalysis of Hemoglobin Immobilized in Porous Mn_2O_3

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Chemical Research in Chinese Universities 2011年第2期27卷 291-294页

作者： shi Lin-pu GAO Qiu-ming School of Chemistry and Environment Beihang University Beijing 100191 P. R. China Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 P. R. China

Novel porous Mn2O3 with good crystallinity was synthesized via hard-template method. Hb-Mn2O3 na-nocomposite was prepared and used for biosensor construction. The Hb-Mn2O3-Nafion modified electrode shows fast direct electron transfer and displays good electrocatalytic response to the reduction of H2O2. The response time is less than 5 s, the sensitivity is as high as 493 μA·L·mmol-1·cm-2 in a linear range of 1-100 μmol/L, and the detection limit is 0.16 μmol/L. This modified electrode also shows good stability and reproducibility. This indicates that the porous Mn2O3 provides a good matrix for enzyme immobilization and biosensor construction.

关键词： Porous Mn203 Biosensor Direct electrochemistry Electrocatalysis Hemoglobin

Entanglement and Phase-Covariant Cloning for Multiple Trapped Ions via Adiabatic Passage

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Communications in Theoretical Physics 2008年第3期49卷 649-651页

We describe a scheme for the generation of W states and implementation of phase-covariant cloning for n trapped ions. The scheme does not use the vibational mode as the memory and works beyond the Lamb-Dicke regime. T... 详细信息

关键词： entanglement trapped ion adiabatic passage

A Hierarchic Method for Studying the Distribution of Phenanthrene in Eisenia fetida

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Pedosphere 2014年第6期24卷 743-752页

作者： shi Zhi-ming XU Li HU Feng College of Resources and Environmental Sciences Nanjing Agricultural University

The distribution of heavy metals in earthworms has been widely studied, highlighting the importance of the fate of these ***, little information is available on the distribution of hydrophobic organic contaminants(HOCs) within earthworms. The aim of this study was to propose a hierarchic method to study the distribution of phenanthrene(PHE), a typical HOC, in Eisenia fetida at several levels: sub-organism(pre-clitellum, clitellum and post-clitellum), tissue(body wall, gut and body fluid) and subcellular(intracellular and extracellular fractions). Earthworms were incubated in the soils amended with low(LC, 10 mg kg-1) and high concentrations(HC, 50 mg kg-1) of PHE and sampled at different time intervals. At the sub-organism level, the distribution of PHE was homogeneous among the sub-organism fractions in the LC treatment but heterogeneous in the HC treatment and gradually reached the following form of post-clitellum ≈ clitellum > pre-clitellum. The uptake and elimination kinetics of PHE in the sub-organism were well described by a one-compartment model. At the tissue level, the concentration of PHE followed the order of gut > body fluid >body wall; while at the subcellular level, the concentration of PHE in the extracellular fraction was 1.23 to 4.68 times higher than that in the intracellular fraction. Therefore, the simple circulatory system of earthworms may account for the PHE distribution at the sub-organism level. Partition pathways(passive diffusion) of PHE between the body wall, body fluid and gut as well as the processes of PHE entrance into the inner cellular compartment via passive diffusion were experimentally supported.

关键词： earthworm passive diffusion subcellular level sub-organism level tissue level

Transparent h-BN/polyacrylamide nanocomposite hydrogels with enhanced mechanical properties

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Chinese Chemical Letters 2016年第9期27卷 1490-1494页

作者： Zhi-Qiang Duan ming Zhong Fu-Kuan shi Xu-ming Xie Laboratory of Advanced Materials (MOE) Department of Chemical Engineering Tsinghua University

In this study, a facile way has been proposed to prepare transparent, tough and flexible polyacrylamide （PAM） hydrogels which is composed of a dually crosslinked single network by chemical crosslinking of N,N＇-methylenebisacrylamide （BIS） and physical crosslinking of hydrophilic hexagonal boron nitride （h- BN） nanosheets. The resulting h-BN/PAM nanocomposite hydrogels are highly transparent, and exhibit significantly enhanced mechanical properties compared to the dark （GO）/PAM nanocomposite hydrogels or chemical crosslinking PAM hydrogels. Thus it opens up new opportunities for developing next- generation transparent, tough and flexible hydrogels that hold great promise in such important applications as light responsive soft robot and liquid microlenses.

关键词： Hexagonal boron nitride Polyacrylamide Nanocomposite hydrogels Mechanical properties Transparency