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Paired quasi-periodic pulsations of hard X-ray emission in a solar flare

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Science China(Physics,Mechanics & Astronomy) 2023年第5期66卷 195-206页

作者： Hai-Sheng Zhao Dong li Shao-lin Xiong Yan-Qiu zhang Yang Su wei chen yi Zhao Xiao-Bo li Jia-Cong liu wen-Xi Peng Rui Qiao Xin-Qiao li xiang-Yang wen li-Ming Song shi-jie Zheng Xin-ying Song Xiao-Yun Zhao Yue huang shuang-Nan zhang shuo Xiao Ce Cai Zheng-hua An Can chen gang chen wei chen Yan-Qi Du Min Gao Ke Gong Dong-Ya guo Zhi-wei guo Jian-Jian He Bin li Chao li Chao-Yang li gang li Jian-Hui li Lu li Qing-Xin li Yan-guo li Jing liang Xiao-hua liang Jin-Yuan liao Xiao-Jing liu Ya-Qing liu Qi Luo xiang Ma Bin Meng Ge Ou Dong-li shi Jing-Yan shi Gong-Xing Sun Xi-Lei Sun You-li Tuo chen-wei Wang Hui Wang Jin Wang Jin-Zhou Wang Ping Wang wen-shuai Wang Hong Wu Sheng-Lun Xie Yan-Bing Xu Yu-Peng Xu Wang-chen xue Sheng Yang Min Yao Jian-ying Ye Qi-Bin yi Chao-Yue zhang Da-li zhang Fan zhang Fei zhang Hong-Mei zhang Kai zhang Peng zhang Xiao-Lu zhang Zhen zhang guo-ying Zhao shi-yi Zhao Chao Zheng Xing Zhou Yue Zhu Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China University of Chinese Academy of Sciences Beijing 100049China Department of Astronomy Beijing Normal UniversityBeijing 100875China School of Computing and Artificial Intelligence Southwest Jiaotong UniversityChengdu 611756China Physics and Space Science College China West Normal UniversityNanchong 637002China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Institute of Astrophysics Central China Normal UniversityWuhan 430079China School of Physics Changchun University of Science and TechnologyChangchun 130022China College of Physics and Engineering Qufu Normal UniversityQufu 273165China College of Physics Sciences&Technology Hebei UniversityBaoding 071002China

We investigate high time resolution data obtained by the Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)during the flare event on 2022 April 21 at 01:52 *** subpeaks with durations of 4-6 s have been detected in the hard X-ray precursor phase,and the key feature is that they appear in pairs and seem like double-peak *** subpeaks are rarely observed in hard X-ray band and confirmed by the microwave obtained by Nobeyama Radio Polarimeters(NoRP)and Radio Solar Telescope Network(RSTN).While an exponential function can describe the continuum component of the time profile from the precursor to part of the impulsive *** periods of quasi-periodic pulsations(QPPs)are detected to be about 7.3 and 12.8 s for the precursor and impulsive phase,respectively,with at least 95%confidence *** paired QPPs are assumed to be double-peak QPPs and then the scenario of current loop coalescence model is found to be in good agreement with our *** precursor phase can be interpreted as the oscillating coalescence of two islands,while the impulsive phase can be interpreted as more islands to coalesce one by one to form larger islands.

关键词： solar flare QPPs loop coalescence circular-ribbon flare

Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-Xin liu Yue huang Guang-cheng Xiao Qing-Cui Bu Jin-Lu Qu shu zhang shuang-Nan zhang shu-Mei Jia Fang-Jun Lu xiang Ma lian Tao wei zhang li chen li-Ming Song Ti-Pei li Yu-Peng Xu xue-Lei Cao Yong chen Cong-Zhan liu Ce Cai Zhi Chang gang chen Tian-xiang chen yi-Bao chen Yu-Peng chen wei Cui wei-wei Cui Jing-Kang Deng Yong-wei Dong Yuan-Yuan Du Min-xue Fu Guan-hua Gao He Gao Min Gao Ming-Yu Ge Yu-Dong Gu Ju Guan cheng-cheng guo Da-wei Han Jia Huo Lu-hua Jiang wei-Chun Jiang Jing Jin Yong-jie Jin ling-Da Kong Bing li cheng-Kui li gang li Mao-shun li wei li Xian li Xiao-Bo li Xu-Fang li Yang-guo li Zheng-wei li Xiao-hua liang Jing-Yuan liao Bai-Sheng liu guo-Qing liu Hong-wei liu Xiao-Jing liu yi-Nong liu Bo Lu xue-Feng Lu Qi Luo Tao Luo Bin Meng yi Nang Jian-yin Nie Ge Ou Na Sai Ren-cheng Shang Xin-ying Song liang Sun ying Tan You-li Tuo chen Wang guo-Feng Wang Juan Wang ling-Jun Wang weng-shuai Wang Yu-Sa Wang xiang-Yang wen Bai-Yang Wu Bo-Bing Wu Mei Wu shuo Xiao Shao-lin Xiong He Xu Jia-wei Yang Sheng Yang Yan-Ji Yang yi-Jung Yang Qi-Bin yi Qian-Qing yin Yuan You Ai-Mei zhang cheng-Mo zhang Fan zhang Hong-Mei zhang Juan zhang Tong zhang Wan-Chang zhang wen-Zhao zhang yi zhang yi-Fei zhang Yong-jie zhang Yuan-Hang zhang Yue zhang Zhao zhang Zhi zhang Zi-liang zhang Hai-Sheng Zhao Xiao-Fan Zhao shi-jie Zheng Yao-Guang Zheng Deng-Ke Zhou Jian-Feng Zhou Yu-Xuan Zhu Ren-lin Zhuang Yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

The In-Flight Realtime Trigger and Localization Software of GECAM

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Research in Astronomy and Astrophysics 2024年第10期24卷 11-24页

作者： Xiao-Yun Zhao Shao-lin Xiong xiang-Yang wen Xin-Qiao li Ce Cai shuo Xiao Qi Luo wen-Xi Peng Dong-Ya guo Zheng-hua An Ke Gong Jin-Yuan liao Yan-Qiu zhang Yue huang Lu li Xing wen Fei zhang Jing Duan chen-wei Wang Dong-li shi Peng zhang Qi-Bin yi Chao-Yang li Yan-Bing Xu Xiao-hua liang Ya-Qing liu Da-li zhang Xi-Lei Sun Fan zhang gang chen huan-Yu Wang Sheng Yang Xiao-Jing liu Min Gao Mao-shun li Jin-Zhou Wang Xing Zhou yi Zhao Wang-chen xue Chao Zheng Jia-Cong liu Xing-Bo Han Jin-ling Qi Jia huang Ke-Ke zhang Can chen Xiong-Tao Yang Dong-jie Hou Yu-Sa Wang Rui Qiao xiang Ma Xiao-Bo li Ping Wang Xin-ying Song li-Ming Song shi-jie Zheng Bing li Hong-Mei zhang Yue Zhu wei chen Jian-Jian He Zhen zhang Jin Hou Hong-Jun Wang Yan-Chao Hao xiang-Yu Wang Zong-Yuan Yang Zhi-Long wen Zhi Chang Yuan-Yuan Du Rui Gao Xiao-Fei Lan Yan-guo li gang li Xu-Fang li Fang-Jun Lu Hong Lu Bin Meng Feng shi Hui Wang Hui-Zhen Wang Yu-Peng Xu Jia-wei Yang xue-Juan Yang shuang-Nan zhang Chao-Yue zhang cheng-Mo zhang Zhi-cheng Tang cheng cheng Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China School of Information Science and Technology Southwest Jiaotong UniversityChengdu 611756China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Physics and Space Science College China West Normal UniversityNanchong 637002China Department of Astronomy Beijing Normal UniversityBeijing 100875China Innovation Academy for Microsatellites of CAS Shanghai 201203China Changchun University of Science and Technology Changchun 130022China Chinese Academy of Sciences South America Center for Astronomy National Astronomical ObservatoriesCASBeijing 100101China

Realtime trigger and localization of bursts are the key functions of GECAM,an all-sky gamma-ray monitor launched on 2020 December *** developed a multifunctional trigger and localization software operating in the CPU of the GECAM Electronic *** onboard software has the following features:high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation,dedicated localization algorithm optimized for both short and long bursts,and low time latency of the trigger information which is downlinked through the Global Short Message Communication service of the global BeiDou navigation *** paper provides a detailed description of the design and development of the trigger and localization software system for *** covers the general design,workflow,the main functions,and the algorithms used in the *** paper also includes on-ground trigger tests using simulated gamma-ray bursts generated by a dedicated X-ray tube,as well as an overview of the performance for real celestial bursts during its in-orbit operation.

关键词： telescopes instrumentation:detectors methods:observational

Data release of the LAMOST pilot survey

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Research in Astronomy and Astrophysics 2012年第9期12卷 1243-1246页

作者： A-li Luo Hao-Tong zhang Yong-Heng Zhao gang Zhao xiang-Qun Cui guo-Ping li Yao-Quan Chu Jian-Rong shi gang Wang Jian-Nan zhang Zhong-Rui Bai Xiao-Yan chen Feng-Fei Wang Yan-Xin guo Jian-Jun chen Bing Du Xiao Kong Ya-Juan Lei yin-Bi li yi-Han Song Yue Wu Yan-Xia zhang Xin-lin Zhou Fang Zuo Peng Du lin He wen Hou yi-Qiao Dong Jian li Guang-wei li shuang li Jing Song Yuan Tian Meng-Xin Wang Yong-Hui Hou Zhi-ying Huo Hong-Zhuan Hu Ning-Sheng Hu Zhong-wen Hu Lei Jia Fang-hua Jiang xiang Jiang Zi-Bo Jiang Ge Jin Ai-hua li Qi li yin-Dun Mao Zheng-Hong Tang Qing-Sheng Tao liang-Ping Tu Da-Qing Wang Dan Wang Jian-Ping Wang Lei Wang Shou-Guan Wang shu-Qing Wang Ya-Nan Wang You Wang Yue-Fei Wang Ming-Zhi wei xiang-xiang xue Xiao-Zheng Xing ling-Zhe Xu Xin-Qi Xu Yan Xu De-hua Yang shi-Hai Yang Zheng-Qiu Yao Yong Yu Hui Yuan Chao Zhai En-Peng zhang Jing zhang li-Ping zhang weizhang Yong zhang Zhen-Chao zhang Ming Zhao Fang Zhou Yong-Tian Zhu jie Zhu Si-cheng Zou National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China lal @ lamost o rg Nanjing Institute of Astronomical Optics and Technology National Astronomical ObservatoriesChinese Academy of Sciences Nanjing 210042 China University of Science and Technologyof China Hefei 230026 China Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China Institute of Architecture Design and Research Chinese Academy of Sciences Beijing 100190China

This paper describes the data release of the LAMOST pilot survey, which includes data reduction, calibration, spectral analysis, data products and data access. The accuracy of the released data and the information about the FITS headers of spectra are also introduced. The released data set includes 319 000 spectra and a catalog of these objects.

关键词： techniques: spectroscopic survey — data reduction — data release

Efficacy and safety of sirolimus early conversion protocol in liver transplant patients with hepatocellular carcinoma:A single-arm, multicenter, prospective study

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Hepatobiliary & Pancreatic Diseases International 2022年第2期21卷 106-112页

作者： Ren-yi Su Sun-Bin ling Qiao-Nan Shan Xu-Yong wei Rui Wang Chang-Ku Jia li Zhuang Tian Shen li-Min Ding Zhi-Dan Xu Lai-Bang Luo li-Bo Sun Guang-Ming li Tai-shi Fang Nan Jiang Kun zhang Zhao-jie Su Zhi-Hai Peng Ren Lang Tao Jiang Qiang He lin-Sen Ye Yang Yang Yu-Ting He wen-Zhi guo liu-Gen Lan Xu-Yong Sun Dong chen Zhi-shui chen Da-wei Zhou Shao-Jun Ye Qi-Fa Ye Min Tian Jian-hua shi Bo Wang Jiang liu Qian Lu wei Rao Jin-Zhen Cai Tao Lv Jia-yin Yang Pu-Sen Wang lin Zhong Jing-Sheng Ma Qi-Gen li Sheng-Dong Wu Chang-Jiang Lu Cai-De Lu Dong-hua zhang Xuan Wang Zi-Qiang li Mu-Jian Teng Jun-jie li wen-Tao Jiang Jian-hua li Quan-Bao zhang Ning-Qi Zhu Zheng-Xin Wang Kang He Qiang Xia Shao-hua Song Zhi-Ren Fu wei Qiu guo-Yue Lv Rui-Peng Song Ji-Zhou Wang Zheng Wang Jian Zhou gang chen ying-Peng Zhao li li Ze-Min Hu Qi-jie Luo Zhong-Zhou Si Bin Xie Xiao-shun He Zhi-Yong guo shu-Sen Zheng Xiao Xu Department of Hepatobiliary and Pancreatic Surgery The Center for Integrated Oncology and Precision MedicineAffiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006China NHC Key Laboratory of Combined Multi-organ Transplantation Hangzhou 310003China Department of Hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalZhejiang Shuren University School of MedicineHangzhou 310022China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Transplantation Jiangxi Provincial People’s Hospital Affiliated to Nanchang UniversityNanchang 330006China liver Transplantation Center Beijing You’an HospitalCapital Medical UniversityBeijing 100069China Department of Hepatic Surgery National Clinical Research Center for Infectious DiseaseShenzhen Third People’s HospitalThe Second Affiliated Hospital of Southern University of Science and TechnologyShenzhen 518112China Department of General Surgery Xiang’an Hospital of Xiamen UniversityXiamen 361000China Deartment of Hepatobiliary and Pancreaticosplenic Surgery Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China Department of Hepatic Surgery and liver Transplantation Center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of liver Transplantation The Second Affiliated Hospital of Guangxi Medical UniversityNanning 530000China Institute of Organ Transplantation Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Institute of Hepatobiliary Diseases of Wuhan University Transplant Center of Wuhan UniversityHubei Key Laboratory of Medical Technology on TransplantationZhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Hepatobiliary Surgery The First Affiliated Hos

Mammalian target of rapamycin(m TOR) inhibitor as an attractive drug target with promising antitumor effects has been widely investigated. High quality clinical trial has been conducted in liver transplant(LT) recipients in Western countries. However, the pertinent studies in Eastern world are paucity. Therefore, we designed a clinical trial to test whether sirolimus can improve recurrence-free survival(RFS) in hepatocellular carcinoma(HCC) patients beyond the Milan criteria after LT. This is an open-labeled, single-arm, prospective, multicenter, and real-world study aiming to evaluate the clinical outcomes of early switch to sirolimus-based regimens in HCC patients after LT. Patients with a histologically proven HCC and beyond the Milan criteria will be enrolled. The initial immunosuppressant regimens are center-specifc for the frst 4-6 weeks. The following regimens integrated sirolimus into the regimens as a combination therapy with reduced calcineurin inhibitors based on the condition of patients and centers. The study is planned for 4 years in total with a 2-year enrollment period and a 2-year follow-up. We predict that sirolimus conversion regimen will provide survival benefts for patients particular in the key indicator RFS as well as better quality of life. If the trial is conducted successfully, we will have a continued monitoring over a longer follow-up time to estimate indicator of overall survival. We hope that the outcome will provide better evidence for clinical decision-making and revising treatment guidelines based on Chinese population data.

关键词： Sirolimus Immunosuppressive agents Hepatocellular carcinoma liver transplantation Conversion

The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-li Luo Yong-Heng Zhao gang Zhao li-Cai Deng Xiao-wei liu yi-Peng Jing gang Wang Hao-Tong zhang Jian-Rong shi xiang-Qun Cui Yao-Quan Chu guo-Ping li Zhong-Rui Bai Yue Wu Yan Cai shu-Yun Cao Zi-huang Cao Jeffrey L.Carlin Hai-Yuan chen Jian-Jun chen Kun-Xin chen li chen xue-Lei chen Xiao-Yan chen ying chen Norbert Christlieb Jia-Ru Chu chen-Zhou Cui yi-Qiao Dong Bing Du Dong-wei Fan Lei Feng Jian-Ning Fu Peng Gao xue-Fei Gong Bo-Zhong Gu Yan-Xin guo Zhan-wen Han Bo-liang He Jin-liang Hou Yong-Hui Hou wen Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-wen Hu Zhi-ying Huo Lei Jia Fang-hua Jiang xiang Jiang Zhi-Bo Jiang Ge Jin Xiao Kong Xu Kong Ya-Juan Lei Ai-hua li Chang-hua li Guang-wei li Hai-Ning li Jian li Qi li shuang li Sha-Sha li Xin-Nan li Yan li yin-Bi li Ye-Ping li Yuan liang Chien-cheng lin Chao liu Gen-Rong liu Guan-Qun liu Zhi-gang liu wen-Zhi Lu Yu Luo yin-Dun Mao Heidi Newberg Ji-Jun Ni Zhao-xiang Qi Yong-Jun Qi shi-yin Shen Huo-Ming shi Jing Song yi-Han Song Ding-Qiang Su Hong-Jun Su Zheng-Hong Tang Qing-Sheng Tao Yuan Tian Dan Wang Da-Qi Wang Feng-Fei Wang guo-Min Wang Hai Wang Hong-Chi Wang Jian Wang Jia-Ning Wang Jian-ling Wang Jian-Ping Wang Jun-Xian Wang Lei Wang Meng-Xin Wang Shou-Guan Wang shu-Qing Wang Xia Wang Ya-Nan Wang You Wang Yue-Fei Wang You-Fen Wang Peng wei Ming-Zhi wei Hong Wu Ke-Fei Wu xue-Bing Wu Yu-Zhong Wu Xiao-Zheng Xing ling-Zhe Xu Xin-Qi Xu Yan Xu Tai-Sheng Yan De-hua Yang Hai-Feng Yang Hui-Qin Yang Ming Yang Zheng-Qiu Yao Yong Yu Hui Yuan Hai-Bo Yuan Hai-Long Yuan wei-Min Yuan Chao Zhai En-Peng zhang hua-wei zhang Jian-Nan zhang li-Pin zhang wei zhang Yong zhang Yan-Xia zhang Zheng-Chao zhang Ming Zhao Fang Zhou Xu Zhou jie Zhu Yong-Tian Zhu Si-cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

The Lyman-alpha Solar Telescope(LST) for the ASO-S mission——Ⅱ. design of LST

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Research in Astronomy and Astrophysics 2019年第11期19卷 33-48页

作者： Bo chen Hui li Ke-Fei Song Quan-Feng guo Pei-jie zhang ling-Ping He shuang Dai Xiao-Dong Wang Hai-Feng Wang Chun-Long liu Hong-Ji zhang Guang zhang Yunqi Wang shi-jie liu Hong-Xin zhang Lei liu shi-Lei Mao Yang liu Jia-Hao Peng Peng Wang liang Sun Yang liu Zhen-wei Han Yan-Long Wang Kun Wu Guang-Xing Ding Peng Zhou Xin Zheng Ming-yi Xia Qing-wen Wu Jin-Jiang Xie Ya chen shu-Mei Song Hong Wang Bo Zhu Chang-Bo Chu wen-gang Yang li Feng Yu huang wei-Qun Gan ying li Jing-wei li Lei Lu Jian-Chao xue Bei-li ying Ming-Zhe Sun cheng Zhu wei-Min Bao Lei Deng Zeng-Shan yin Changchun Institute of Optics FineMechanics and PhysicsChinese Academy of SciencesChangchun 130033China State Key Laboratory of Applied Optics Changchun 130033China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210034China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China Xi’an Institute of Optics and Precision Mechanics Chinese Academy of SciencesXi’an 710119China Shandong University Weihai 264209China Innovation Academy for Microsatellites Chinese Academy of SciencesShanghai 201210China

As one of the three payloads for the Advanced Space-based Solar Observatory(ASO-S)mission,the Lyman-alpha(Lyα)Solar Telescope(LST)is composed of three instruments:a Solar Corona Imager(SCI),a LyαSolar Disk Imager(SDI)and a full-disk White-light Solar Telescope(WST).When working in-orbit,LST will simultaneously perform high-resolution imaging observations of all regions from the solar disk to the inner corona up to 2.5 R⊙(R⊙stands for the mean solar radius)with a spatial resolution of 4.8′′and 1.2′′for coronal and disk observations,respectively,and a temporal resolution of 30–120 s and 1–120 s for coronal and disk observations,*** maximum exposure time can be up to20 s due to precise pointing and image stabilization *** the three telescopes of LST,SCI is a dual-waveband coronagraph simultaneously and independently observing the inner corona in the HI Lyα(121.6±10 nm)line and white light(WL)(700±40 nm)wavebands by using a narrowband Lyαbeam splitter and has a field of view(FOV)from 1.1 to 2.5 R⊙.The stray-light suppression level can attain10^-6 B⊙(B⊙is the mean brightness of the solar disk)at 1.1 R⊙and≤5×10^-8 B⊙at 2.5 R⊙.SDI and WST are solar disk imagers working in the Lyαline and 360.0 nm wavebands,respectively,which adopt an off-axis two-mirror reflective structure with an FOV up to 1.2 R⊙,covering the inner coronal edge area and relating to coronal *** present the up-to-date design for the LST payload.

关键词： telescopes—instrumentation high angular resolution—Sun flares—Sun coronal mass ejections(CMEs)—Sun UV radiation

Original article Efficacy and safety of Changfu peritoneal dialysis solution： a multi-center prospective randomized controlled trial

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Chinese Medical Journal 2013年第22期126卷 4204-4209页

作者： ZHOU Jian-hui NI Zhao-hui MEI Chang-lin YU xue-qing liU Fu-you MIAO li-ning liU Zhi-hong YUAN wei-jie zhang Ai-ping lin Hong-li chen Meng-hua chen Jiang-hua zhang Jin-yuan HE Ya-ni chen Jian ZHAO Jiu-yang DING Xiao-qiang li ying li Rong-shan XIE Ru-juan liU wen-hu XING Chang-ying WANG Rong DENG Yue-yi CAO xue-ying CAI Guang-yan MOU Shan MAO Zhi-guo YANG Xiao liU Hong SUN Jing YU Yu-sheng liU Jun shi shu-mei li Long-kai TIAN Na zhang Xiao-hui ZHOU wei YANG jie zhang Yong SUN Jing-di JI Jun zhang Tao YAN Yan liU Xiao-gang WANG gang zhang li zhang Hong LUO Jian-hua chen xiang-mei Department of Nephrology State Key Laboratory of Kidney Disease Chinese People's Liberation Army General Hospital Beijing 100853 China Renal Division Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200127 China

Background A multi-center large scale study is needed to confirm the efficacy and safety of domestic peritoneal dialysis （PD） solutions. Some researchers believe that 6 lid is enough for adequate dialysis, but there is no multi-center prospective study on Chinese population to confirm this. In this study, we evaluated the efficacy and safety of domestic PD solution （Changfu） and its difference between 6 L and 8 L dosage. Methods Adult PD patients who had taken PD therapy for at least one month were selected and divided into four groups according to two dialysis solution brands and two dialysis dosages, i.e., 6 L dose with Changfu dialysis solution, 6 L dose with Baxter dialysis solution, 8 L dose with Changfu dialysis solution, and 8 L dose with Baxter dialysis solution. After 48 weeks, the changes of primary and secondary efficacy indices were compared between different types and different dosages. We also analyzed the changes of safety indices. Results Changes of Kt/V from baseline to 48 weeks between Changfu and Baxter showed no statistical differences; so did those of creatinine clearance rate （Ccr）. Normalized protein catabolic rate （nPCR） from baseline to 48 weeks between Changfu and Baxter showed no statistical differences; so did those of net ultrafiltration volume （nUF） and estimated glomerular filtration rate （eGFR）. Changes of nPCR from baseline to 48 weeks between 6 L and 8 L showed no statistical differences; so did those of nUF and eGFR. The decline of Kt/V from baseline to 48 weeks in 6 L group was more than that in 8 L group. Change of Ccr was similar. During the 48-week period, the mean Kt/V was above 1.7/w, and mean Ccr was above 50 L.1.73 m-2.w1. More adverse events were found in Changfu group before Changfu Corporation commenced technology optimization, and the statistical differences disappeared after that. Conclusions The domestic PD solution （Changfu） was proven to be as effective as Baxter dialysis solution. During 48- week period, a dosage o

关键词： Changfu peritoneal dialysis solution efficacy safety

Expert Consensus on Pathological Diagnosis of Intrahepatic Cholangiocarcinoma(2022 version)

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Journal of Clinical and Translational Hepatology 2023年第7期11卷 1553-1564页

作者： Han Wang Jun chen Xin zhang Xia Sheng Xiao-Yan Chang jie chen Min-Shan chen Hui Dong Guang-jie Duan He-Ping Hu Zhi-Yong huang wei-Dong Jia Xiao-Qing Jiang Dong Kuang Shan-Shan li Zeng-Shan li Chang-li Lu shu-Kui Qin xue-Shan Qiu li-Juan Qu Chun-Kui Shao Feng Shen guo-Ming shi Su-Sheng shi Yu-Jun shi Hui-Chuan Sun Xiao-Dong Teng Bin Wang Zhan-Bo Wang Tian-Fu wen Jia-Mei Yang Qiao-Qiao Yang Sheng-Long Ye Hong-Fang yin Zhen-gang Yuan Jing-Ping Yun Feng-lin Zang Hong-Qi zhang li-Hong zhang Jing-Min Zhao Jian Zhou wei-Xun Zhou Jia Fan Xiao-Ping chen Wan Yee Lau Yuan Ji wen-Ming Cong Chinese Society of liver Cancer of Chinese Anti-Cancer Association Digestive Disease Group of Chinese Society of Pathology,Chinese Medical Association Chinese Society of Pathology of Chinese Anti-Cancer Association Hepatic Surgery Group of Chinese Society of Surgery,Chinese Medical Association Biliary Tract Tumor Committee of China Anti-Cancer Association Chinese Society of Clinical Oncology IDepartment of Pathology Eastern Hepatobilary Surgery HospitalNaval Medical UniversityShanghaiChina Department of Pathology the Affiliated Drum Tower HospitalNanjing University Medical SchoolNanjingJiangsuChina Department of Pathology Zhongshan HospitalFudan UniversityShanghaiChina Department of Pathology Minhang HospitalFudan Uni-versityShanghaiChina Department of Pathology Peking Union Medical College HospitalChinese Academy of Medical Sci-ences and Peking Union Medical CollegeBeijingChina Department of liver Surgery Sun Yat-Sen University Cancer CenterGuangzhouGuangdongChina Department of Pathology The First Affiliated HospitalArmy Medical UniversityChongqingChina Department of Hepatobiliary Medicine Eastern Hepatobiliary Surgery HospitalNaval Medical UniversityShanghaiChina Hepatic Surgery Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWu-hanHubeiChina Department of General Surgery The First Affliated Hospital of USTCDivision of Life Science and Medi-cineUniversity of Science and Technology of ChinaHefeiAnhuiChina Department of Biliary Surgery I Eastern Hepatobil-iary Surgery HospitalNaval Medical UniversityShanghaiChina Department of Pathology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiChina Department of Pathology The First Afiliated Hospital of Zhengzhou UniversityZhengzhou UniversityZhengzhouHenanChina Department of Pathology Xijing Hospi-talAir Force Medical UniversityXi'anShaanxiChina Department of Pathology West China HospitalSichuan UniversityChengduSichuanChina Cancer Center of Jinling Hospital Nanjing University of Chinese MedicineNanjingJiangsuChina Department of Pathology The First Affiliated HospitalChina Medical UniversityShenyangLiaoningChina Department of Pathology The 900 Hospital of the Chinese People's Liberation Army Joint Logistics TeamFuzhouFujianChina Department of Pathology The Third Affiliated HospitalSun Yat-Sen UniversityGuangz

Intrahepatic cholangiocarcinoma(iCCA)can originate from the large bile duct group(segment bile ducts and area bile ducts),small bile duct group(septal bile ducts and interlobular bile ducts),and terminal bile duct group(bile ductules and canals of Hering)of the intrahepatic biliary tree,which can be histopathological corresponding to large duct type iCCA,small duct type iCCA and iCCA with ductal plate malformation pattern,and cholangiolocarcinoma,*** challenge in pathological diagnosis of above subtypes of iCCA falls in the distinction of cellular morphologies,tissue structures,growth patterns,invasive behaviors,immunophenotypes,molecular mutations,and surgical *** these reasons,this expert consensus provides nine recommendations as a reference for standardizing and refining the diagnosis of pathological subtypes of iCCA,mainly based on the 5th edition of the World Health Organization Classification of Tumours of the Digestive System.

关键词： Intrahepatic cholangiocarcinoma Pathology Histological type Immunohistochemistry Molecular variation