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基于社会支持和信息-动机-行为技巧模型的护理干预方案在妊娠糖尿病孕妇中的应用

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中国现代医生 2024年第4期62卷 94-98页

作者：陈晓君方金瓶施丽芳浙江大学医学院附属第二医院临平院区产科浙江杭州3111001

目的探讨基于社会支持和信息-动机-行为技巧模型的护理干预方案对妊娠糖尿病孕妇的临床效果。方法选取2020年2月至2022年2月浙江大学医学院附属第二医院临平院区收治的104例妊娠糖尿病孕妇为研究对象,采用随机数字表法将其分为试验组和... 详细信息

目的探讨基于社会支持和信息-动机-行为技巧模型的护理干预方案对妊娠糖尿病孕妇的临床效果。方法选取2020年2月至2022年2月浙江大学医学院附属第二医院临平院区收治的104例妊娠糖尿病孕妇为研究对象,采用随机数字表法将其分为试验组和对照组,每组各52例。对照组孕妇给予常规护理干预,试验组孕妇在常规护理的基础上给予基于社会支持和信息-动机-行为技巧模型的护理干预方案,比较两组孕妇干预前后的抑郁-焦虑-压力量表、疾病认知和健康行为情况、孕期血糖控制情况、围产期母婴并发症及分娩方式。结果干预后,试验组孕妇的抑郁、焦虑、压力评分及空腹血糖、餐后2h血糖、糖化血红蛋白水平均显著低于对照组,疾病认知情况、健康促进生活方式问卷评分及阴道分娩率均显著高于对照组(P<0.05)。试验组孕妇、围产儿的并发症发生率均显著低于对照组(P<0.05)。结论基于社会支持和信息-动机-行为技巧模型的护理干预方案对妊娠糖尿病孕妇的干预效果良好,可使孕妇获得更多的社会支持,减少负面情绪,改善健康行为,促进血糖控制,提高自然分娩率。

关键词：妊娠糖尿病社会支持信息-动机-行为技巧模型

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F-Actin reassembly during focal adhesion impacts single cell mechanics and nanoscale membrane structure

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Science China Chemistry 2012年第9期55卷 1922-1930页

作者： ZIMMER Christopher C shi lifang shiH YiPing LI JieRen JIN LeeWay LO SuHao LIU GangYu Department of Chemistry University of California Davis CA 95616 USA Department of Biochemistry and Molecular Medicine Center.for Tissue Regeneration and Repair University of California Davis Medical Center Sacramento CA 95817 USA M.I.N.D. Institute and Department of Pathology and Laboratory Medicine ' Alzheimer's Disease Center University of California Davis Medical Center Sacramento CA 95817 USA

Focal adhesions play an important role in cell spreading,migration,and overall mechanical *** relationship of cell structural and mechanical properties was investigated in the context of focal adhesion *** atomic force microscopy(AFM) and laser scanning confocal microscopy(LSCM) was utilized to measure single cell mechanics,in correlation with cellular morphology and membrane structures at a nanometer *** stages of focal adhesion were verified via confocal fluorescent studies,which confirmed three representative F-actin assemblies,actin dot,filaments network,and long and aligned fibrous bundles at ***-deformation profiles of living cells were measured at the single cell level,and displayed as a function of height deformation,relative height deformation and relative volume *** focal adhesion progresses,single cell compression profiles indicate that both membrane and cytoskeleton stiffen,while spreading increases especially from focal complex to focal ***,AFM imaging reveals morphological geometries of spherical cap,spreading with polygon boundaries,and elongated or polarized *** features are dominated by protrusions of 41-207 nm tall,short rods with 1-6 μm in length and 10.2-80.0 nm in height,and long fibrous features of 31-246 nm tall,*** protrusion is attributed to local membrane folding,and the rod and fibrous features are consistent with bilayer decorating over the F-actin *** collectively,the reassembly of F-actin during focal adhesion formation is most likely responsible for the changes in cellular mechanics,spreading morphology,and membrane structural features.

关键词： focal adhesion actin fibers actin assembly fibroblast membrane structure single cell mechanics atomic forcemicroscopy laser scanning confocal microscopy

Supramolecular assembly of chloroplast NADH dehydrogenase-like complex with photosystem Ⅰfrom Arabidopsis thaliana

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Molecular Plant 2022年第3期15卷 454-467页

作者： Xiaodong Su Duanfang Cao Xiaowei Pan lifang shi Zhenfeng Liu Luca Dall’Osto Roberto Bassi Xinzheng Zhang Mei Li National Laboratory of Biomacromolecules CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101P.R.China University of Chinese Academy of Sciences Beijing 100049P.R.China College of Life Science Capital Normal UniversityBeijing 100101P.R.China Dipartimento di Biotecnologie Universitàdi Verona37134 VeronaItaly Center for Biological Imaging CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101P.R.China

Cyclic electron transport/flow(CET/CEF)in chloroplasts is a regulatory process essential for the optimization of plant photosynthetic efficiency.A crucial CEF pathway is catalyzed by a membrane-embedded NADH dehydrogenase-like(NDH)complex that contains at least 29 protein subunits and associates with photosystem I(PSI)to form the NDH-PSI ***,we report the 3.9Åresolution structure of the Arabidopsis thaliana NDH-PSI(AtNDH-PSI)*** constructed structural models for 26 AtNDH subunits,among which 11 are unique to chloroplasts and stabilize the core part of the NDH *** the supercomplex,one NDH can bind up to two PSI-light-harvesting complex I(PSI-LHCI)complexes at both sides of its membrane *** minor LHCIs,Lhca5 and Lhca6,each present in one PSI-LHCI,interact with NDH and contribute to supercomplex formation and ***,our study reveals the structural details of the AtNDH-PSI supercomplex assembly and provides a molecular basis for further investigation of the regulatory mechanism of CEF in plants.

关键词： cyclic electron transport/flow NADH dehydrogenase-like(NDH)complex photosystem I structure Arabidopsis thaliana

Mitochondrial microsatellite instability in gastric cancer and its precancerous lesions

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World Journal of Gastroenterology 2004年第6期10卷 800-803页

作者： Xian-LongLing Dian-ChunFang Rong-QuanWang shi-MingYang lifang DepartmentofGastroenterology SouthwestHospitalThirdMilitaryMedicalUniversityChongqing400038China

AIM:To evaluate the role of mitochondrial microsatellite instability (mtMSI) in gastric ***:MtMSI was measured with PCR-single strand conformation polymophism (PCR-SSCP) in 68 cases of advanced gastric cancer,40 cases of chronic gastritis,30 cases of intestinal metaplasia and 20 cases of ***:MtMSI was observed in 12.5% (5 of 40) of chronic gastritis,20.0% (6 of 30) of intestinal metaplasia,25.0% (5 of 20) of dysplasia and 38.2% (26 of 68) of gastric *** findings showed a sequential accumulation of mtMSI in the histological progression from chonic gastritis to gastric cancer. An association of mtMSI with intestinal histological type and distal location was found (P=0.001 and P=0.002), whereas no significant correlation was found between mtMSI and age at diagnosis, sex, tumor size, depth of invasion, lymph node spread and clinical stages (P>0.05).CONCLUSION:MtMSI may play an early and important role in the gastric carcinogenesis pathway, especially in the intestinal type and distal gastric cancer.

关键词：线粒体微卫星稳定性胃癌癌前病变临床意义 PCR-SSCP

Design and experimental verification of a monolithic complete-light modulator based on birefringent materials

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Photonics Research 2019年第8期7卷 875-882页

作者： YINGFEI PANG AXIU CAO JIAZHOU WANG HUI PANG WEI YAN XIANGDONG WU lifang shi QILING DENG Institute of Optics and Electronics Chinese Academy of SciencesChengdu610209China School of Mechanical Engineering Southwest Jiaotong UniversityChengdu610031China University of Chinese Academy of Sciences Beijing100049China

This paper presents a method to design a monolithic complete-light modulator(MCLM) that fully controls the amplitude, phase, and polarization of incident light. The MCLM is made of birefringent materials that provide different refractive indices to orthogonal eigen-polarizations, the ordinary o and extraordinary e states. We propose an optimization method to calculate the two relief depth distributions for the two eigen-polarizations. Also, a merging algorithm is proposed to combine the two relief depth distributions into one. The corresponding simulations were carried out in this work and the desired light distribution, including information on amplitude,phase, and four polarization states, was obtained when a laser beam passed through a 16-depth-level microstructure whose feature size is 8 μm. The structure was fabricated by common photolithography. An experimental optical system was also set up to test the optical effects and performances of the MCLM. The experimental performance of the MCLM agrees with the simulation results, which verifies the validity of the algorithms we propose in this paper.

关键词： Design and experimental verification birefringent materials complete-light modulator

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关于中外大学校长培训模式的思考

国家教育行政学院学报 2009年第8期140卷 91-95页

作者：史莉芳山西大学政治与公共管理学院山西太原030006

高等教育的发展要求进一步加强大学校长队伍建设,提高大学校长的培训水平。目前我国在实践过程中形成了颇为有效的大学校长培训模式,但是也存在着突出的问题,文章希望借鉴其他国家的成功经验,不断对大学校长的培训模式进行改革和完善,... 详细信息

高等教育的发展要求进一步加强大学校长队伍建设,提高大学校长的培训水平。目前我国在实践过程中形成了颇为有效的大学校长培训模式,但是也存在着突出的问题,文章希望借鉴其他国家的成功经验,不断对大学校长的培训模式进行改革和完善,稳步实现校长培训的专业化、正规化,加快我国建设世界一流大学的步伐。

关键词：大学校长中国培训模式外国培训模式

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管理的视角:组织资本及其投资

国际经济合作 2006年第4期 60-63页

作者：施丽芳南京大学商学院

作为企业的一种独特生产资源,组织资本被视为影响公司绩效和增长的最重要因素之一.但它的无形特征以及对人的依赖性,使得这个经济学概念非常抽象,难以被清晰描述理解,这直接阻碍了将组织资本这一概念用于指导管理实践.本文试图建立一个... 详细信息

作为企业的一种独特生产资源,组织资本被视为影响公司绩效和增长的最重要因素之一.但它的无形特征以及对人的依赖性,使得这个经济学概念非常抽象,难以被清晰描述理解,这直接阻碍了将组织资本这一概念用于指导管理实践.本文试图建立一个分析框架,引入组织的记忆这一管理学的概念,来帮助研究者和管理者们从管理视角理解企业所拥有的组织资本这一重要资产,进而理解对组织资本的投资.

关键词：组织资本管理实践投资经济学概念生产资源公司绩效依赖性管理学管理者研究者

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对企业购并三个基本要素的探讨

国际经济合作 2006年第2期 19-20页

作者：施丽芳南京大学商学院

公司购并是一个复杂的过程,涉及经济、政治、法律、文化以及历史等各方面的因素,牵涉面广,影响大,它需要企业对目标企业和外部环境和企业的状况做出综合评价和判断.国际上成功的大企业几乎都发生过多次购并活动才取得今天的规模和优势.... 详细信息

公司购并是一个复杂的过程,涉及经济、政治、法律、文化以及历史等各方面的因素,牵涉面广,影响大,它需要企业对目标企业和外部环境和企业的状况做出综合评价和判断.国际上成功的大企业几乎都发生过多次购并活动才取得今天的规模和优势.笔者认为,购并前周密的规划、确定合理的收购溢价和购并后整合的效果,是决定一项购并能否成功的三大基本要素.

关键词：企业购并公司购并购并活动综合评价外部环境目标企业大企业成功经济国际

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政务超市——新时期中国政府管理的新模式

国家行政学院学报 2008年第5期 35-37页

作者：史莉芳山西大学太原030006

政务超市是我国政府改革的一项创新,它在政府管理活动中引入了商业模式,运用市场的方法来管理公共事务,转变政府职能,推行行政体制改革,本文对政务超市的基本内涵及其发展现状进行研究,发现存在的问题并总结和归纳出在我国完善政务超市... 详细信息

政务超市是我国政府改革的一项创新,它在政府管理活动中引入了商业模式,运用市场的方法来管理公共事务,转变政府职能,推行行政体制改革,本文对政务超市的基本内涵及其发展现状进行研究,发现存在的问题并总结和归纳出在我国完善政务超市的对策。

关键词：政务超市新公共管理职能转变