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Immune checkpoint inhibitor-associated gastritis:Patterns and management

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World Journal of Gastroenterology 2024年第14期30卷 1941-1948页

作者： jing Lin Zhong-Qiao Lin shi-Cheng Zheng Yu Chen Department of Medical Oncology Clinical Oncology School of Fujian Medical UniversityFujian Cancer HospitalFuzhou 350000Fujian ProvinceChina Phase I Clinical Trial Ward Clinical Oncology School of Fujian Medical UniversityFujian Cancer HospitalFuzhou 350000Fujian ProvinceChina School of Basic Medical Sciences Fujian Medical UniversityFuzhou 350000Fujian ProvinceChina

Immune checkpoint inhibitors(ICIs)are widely used due to their effectiveness in treating various ***-related adverse events(irAEs)are defined as adverse effects resulting from ICI *** irAEs are a common type of irAEs characterized by intestinal side effects,such as diarrhea and colitis,which may lead to the cessation of *** irAE gastritis is rarely reported,it may lead to serious complications such as ***,irAE gastritis is often difficult to identify early due to its diverse *** steroid hormones and immunosuppressants are commonly used to reverse irAEs,the best regimen and dosage for irAE gastritis remains *** addition,the risk of recurrence of irAE gastritis after the reuse of ICIs should be *** this editorial,strategies such as early identification,pathological diagnosis,mana-gement interventions,and immunotherapy rechallenge are discussed to enable clinicians to better manage irAE gastritis and improve the prognosis of these patients.

关键词： Immunotherapy Immune checkpoint inhibitor Immune-related adverse events Immune checkpoint inhibitor-related gastritis

Epidermal visualized health monitoring system based on stretchable and washable TPU hybrid conductive microtextiles

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Rare Metals 2024年第7期43卷 3185-3193页

作者： jing-Bo Yuan Zhi-hong Feng Dong-Chan Li Yang Luo Yun-Lei Zhou School of Chemical Engineering Hebei University of Technology Engineering Research Center of Chemical Technology for Efficient Utilization of Seawater ResourcesMinistry of EducationTianjin 300401China National Key Laboratory of Application Specific Integrated Circuit Shijiazhuang050000China Department of Materials ETH Zürich8093 ZurichSwitzerland Hangzhou Institute of Technology Xidian UniversityHangzhou 311231China

Electronic textiles,an emerging class of electronic technology,offer exciting opportunities for seamless integration with the human *** applications have been developed based on electronic ***,researches on integrating multiple electronic textilebased devices are still *** this study,we present a system integrated with an electrocardiogram monitoring sensor and an electroluminescence device based on stretchable and washable conductive micro *** signal is acquired by an electrocardiograph amplifier and displayed by a dual-color electroluminescence device based on the processed *** integrated electronic device has excellent moisture permeability and comfort for long-term *** system reported in this study opens a new avenue for the application of electronic textiles in health monitoring,robotic prosthetics,and competitive sports.

关键词： Conductive microtextile Textile composite Electronic textile Electroluminescent displays

Prediction of novel layered indium halide superconductors

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Chinese Physics B 2024年第10期33卷 388-393页

作者： Zhi-hong Yuan jing-jing Meng Rui Liu Peng-Yu Zheng Zhi-Ping Yin School of Physics&Astronomy and Center for Advanced Quantum Studies Beijing Normal UniversityBeijing 100875China School of Physics and Information Engineering Shanxi Normal UniversityTaiyuan 030031China Key Laboratory of Multiscale Spin Physics(Ministry of Education) Beijing Normal UniversityBeijing 100875China

We design two new layered indium halide compounds LaOInF_(2)and LaOInCl_(2)by means of first-principles calculations and evolutionary crystal structure *** find both compounds crystallize in a tetragonal structure with P4/nmm space group and have indirect band gaps of 2.58 eV and 3.21 eV,*** substituting O with F,both of them become metallic and superconducting at low *** F-doping leads to strong electron-phonon coupling in the low-energy acoustic phonon modes which is mainly responsible for the induced *** total electron-phonon coupling strength are 1.86 and 1.48,while the superconducting transition temperature(T_(c))are about 7.2 K and 6.5 K with 10%and 5%F doping for LaOInF_(2)and LaOInCl_(2),respectively.

关键词： superconductor LaOInF_(2) LaOInCl_(2) electron-phonon coupling

A method for establishing a bearing residual life prediction model for process enhancement equipment based on rotor imbalance response analysis

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Chinese Journal of Chemical Engineering 2024年第2期66卷 203-215页

作者： Feng Wang Haoran Li Zhenghui Zhang Yan Bai hong Yin jing Bian National Foundation Research Laboratory of Fault Prevention and Control in Hazardous Chemicals Production System Engineering Research Center of Chemical Technology SafetyBeijing University of Chemical TechnologyBeijing 100029China China Nuclear Power Engineering Co. LtdBeijing 100840China CNOOC Tianjin Chemical Research and Design Institute Co. LtdTianjin Key Laboratory of Energy and Chemical Explosion SafetyAcademician Expert Collaborative Innovation CenterTianjin 300131China

A rotating packed bed is a typical chemical process enhancement equipment that can strengthen micromixing and mass *** the operation of the rotating packed bed,the nonreactants and products irregularly adhere to the wire mesh packing in the rotor,thus resulting in an imbalance in the vibration of the rotor,which may cause serious damage to the bearing and material *** study proposes a model prediction for estimating the bearing residual life of a rotating packed bed based on rotor imbalance response *** method is used to determine the influence of the mass on the imbalance in the vibration of the rotor on bearing *** major influence on rotor vibration was found to be exerted by the imbalanced mass and its distribution radius,as revealed by the results of orthogonal *** implementing finite element analysis,the imbalance response curve for the rotating packed bed rotor was obtained,and a correlation among rotor imbalance mass,distribution radius of imbalance mass,and bearing residue life was established via data *** predicted value of the bearing life can be used as the reference basis for an early safety warning of a rotating packed bed to effectively avoid accidents.

关键词： Rotating packed bed Mass imbalance Harmonic response analysis Residual life Prediction model

Noise-Tolerant ZNN-Based Data-Driven Iterative Learning Control for Discrete Nonaffine Nonlinear MIMO Repetitive Systems

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IEEE/CAA Journal of Automatica Sinica 2024年第2期11卷 344-361页

作者： Yunfeng Hu Chong Zhang Bo Wang jing Zhao Xun Gong Jinwu Gao hong Chen State Key Laboratory of Automotive Simulation and Control Jilin UniversityJilin UniversityChangchun 130025China College of Communication Engineering Jilin UniversityJilin UniversityChangchun 130025China Department of Electromechanical Engineering University of MacaoMacao 999078China School of Artificial Intelligence Jilin UniversityChangchun 130012China IEEE College of Electronics and Information Engineering Tongji UniversityShanghai 200092China

Aiming at the tracking problem of a class of discrete nonaffine nonlinear multi-input multi-output(MIMO) repetitive systems subjected to separable and nonseparable disturbances, a novel data-driven iterative learning control(ILC) scheme based on the zeroing neural networks(ZNNs) is proposed. First, the equivalent dynamic linearization data model is obtained by means of dynamic linearization technology, which exists theoretically in the iteration domain. Then, the iterative extended state observer(IESO) is developed to estimate the disturbance and the coupling between systems, and the decoupled dynamic linearization model is obtained for the purpose of controller synthesis. To solve the zero-seeking tracking problem with inherent tolerance of noise,an ILC based on noise-tolerant modified ZNN is proposed. The strict assumptions imposed on the initialization conditions of each iteration in the existing ILC methods can be absolutely removed with our method. In addition, theoretical analysis indicates that the modified ZNN can converge to the exact solution of the zero-seeking tracking problem. Finally, a generalized example and an application-oriented example are presented to verify the effectiveness and superiority of the proposed process.

关键词： Adaptive control control system synthesis data-driven iterative learning control neurocontroller nonlinear discrete time systems

MADRL-based UAV swarm non-cooperative game under incomplete information

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Chinese Journal of Aeronautics 2024年第6期37卷 293-306页

作者： Ershen WANG Fan LIU Chen hong jing GUO Lin ZHAO Jian XUE Ning HE School of Electronic and Information Engineering Shenyang Aerospace UniversityShenyang 110136China College of Robotics Beijing Union UniversityBeijing 100101China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China College of Smart City Beijing Union UniversityBeijing 100101China

Unmanned Aerial Vehicles(UAVs)play increasing important role in modern *** this paper,considering the incomplete observation information of individual UAV in complex combat environment,we put forward an UAV swarm non-cooperative game model based on Multi-Agent Deep Reinforcement Learning(MADRL),where the state space and action space are constructed to adapt the real features of UAV swarm air-to-air *** multi-agent particle environment is employed to generate an UAV combat scene with continuous observation *** recently popular MADRL methods are compared extensively in the UAV swarm noncooperative game model,the results indicate that the performance of Multi-Agent Soft Actor-Critic(MASAC)is better than that of other MADRL methods by a large *** swarm employing MASAC can learn more effective policies,and obtain much higher hit rate and win *** under different swarm sizes and UAV physical parameters are also performed,which implies that MASAC owns a well generalization ***,the practicability and convergence of MASAC are addressed by investigating the loss value of Q-value networks with respect to individual UAV,the results demonstrate that MASAC is of good practicability and the Nash equilibrium of the UAV swarm non-cooperative game under incomplete information can be reached.

关键词： UAV swarm Reinforcement learning Deep learning Multi-agent Non-cooperative game Nash equilibrium

Recyclable High-performance Carbon Fiber Reinforced Epoxy Composites Based on Dithioacetal Covalent Adaptive Network

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Chinese Journal of Polymer Science 2024年第10期42卷 1514-1524,I0011页

作者： Gui-Lian shi Ting-Cheng Li Dao-hong Zhang Jun-Heng Zhang Key Laboratory of Catalysis and Energy Materials Chemistry of Ministry of Education&Hubei Key Laboratory of Catalysis and Materials Science Hubei R&D Center of Hyperbranched Polymers Synthesis and ApplicationsSouth-Central Minzu UniversityWuhan430074China State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan430200China Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials Hubei UniversityWuhan430062Chin

Recycling of carbon fiber reinforced composites is important for sustainable development and the circular *** the use of dynamic chemistry,developing high-strength recyclable CFRPs remains a major challenge due to the mutual exclusivity between the dynamic and mechanical properties of ***,we developed a high-strength recyclable epoxy resin(HREP)based on dynamic dithioacetal covalent adaptive network using diglycidyl ether bisphenol A(DGEBA),pentaerythritol tetra(3-mercapto-propionate)(PETMP),and vanillin epoxy resin(VEPR).At high temperatures,the exchange reaction of thermally activated dithioacetals accelerated the rearrangement of the network,giving it significant reprocessing ***,HREP exhibited excellent solvent resistance due to the increased cross-linking *** this high-strength recyclable epoxy resin as the matrix and carbon fiber modified with hyperbranched ionic liquids(HBP-AMIM+PF6-)as the reinforcing agent,high performance CFRPs were successfully *** tensile strength,interfacial shear strength(IFSS)and interlaminar shear strength(ILSS)of the optimized formulation(HREP20/CF-HBPPF6)were 1016.1,70.8 and 76.0 MPa,*** addition,the CFRPs demonstrated excellent solvent and acid/*** CFRPs could completely degrade within 24 h in DMSO at 140℃,and the recycled CF still maintained the same tensile strength and ILSS as the original after multiple degradation cycles.

关键词： Epoxy resin Hyperbranched ionic liquid Recycling Carbon fiber Composites

Clinical significance of serum intercellular adhesion molecule-i detection in patients with hepatocellular carcinoma

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World Journal of Gastroenterology 2000年第3期6卷 408-410页

作者： Ming Hui Mei jing Xu Qin Fen shi jing hong Yang Qian CHen Li Ling Qin Department of Hepatobiliary Surgery, Institute of Hepatobiliary Surgery,Guilin Medical College,Guilin 541001,Guangxi Province,China

INTRODUCTION Since the late 1980s,studies on the expression ofintercellular adhesion molecule-1(ICAM-1)inpatients with malignancies have demonstrated thatICAM-1 may strongly express in two forms in suchdiseases:membra... 详细信息

关键词： carcinoma hepatocellular/diagnosis intercellular adhesion molecule-1 liverneoplasms/diagnosis alpha-fetoprotein

Synthesizing high-resolution satellite salinity data based on multi-fractal fusion

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Acta Oceanologica Sinica 2024年第7期43卷 112-124页

作者： Hengqian Yan Jian shi Ren Zhang Wangjiang Hu Yongchui Zhang Mei hong College of Meteorology and Oceanography National University of Defense TechnologyChangsha 410073China

The spaceborne platform has unprecedently provided the global eddy-permitting(typically about 0.25°)products of sea surface salinity(SSS),however the existing SSS products can hardly resolve mesoscale motions due to the heavy noises therein and the over-smoothing in denoising *** means of the multi-fractal fusion(MFF),the high-resolution SSS product is synthesized with the template of sea surface temperature(SST).Two low-resolution SSS products and four SST products are considered as the source data and the templates respectively to determine the best *** fused products are validated by the in situ observations and intercompared via SSS maps,Singularity Exponent maps and wavenumber *** results demonstrate that the MFF can perform a good work in mitigating the noises and improving the *** combination of the climate change initiative SSS and the remote sensing system SST can produce the 0.1°denoised product whose global mean standard derivation of salinity against Argo is 0.21 and the feature resolution can reach 30−40 km.

关键词： sea surface salinity multi-fractal fusion high resolution