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神经肌肉电刺激联合本体感觉训练治疗青少年特发性脊柱侧弯的疗效研究

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河北医药 2024年第9期46卷 1361-1364页

作者：徐辉赵义沈阳上海交通大学医学院附属儿童医院骨科上海市200062 上海浦滨儿童医院康复科

目的探讨神经肌肉电刺激联合本体感觉训练治疗青少年特发性脊柱侧弯(AIS)的应用效果。方法采用前瞻性随机对照分析,纳入2.2.年1月至2.2.年3月收治的93例AIS患儿为研究对象,根据随机数字表法分为观察组(n=47)和对照组(n=46)。对照组采用... 详细信息

目的探讨神经肌肉电刺激联合本体感觉训练治疗青少年特发性脊柱侧弯(AIS)的应用效果。方法采用前瞻性随机对照分析,纳入2.2.年1月至2.2.年3月收治的93例AIS患儿为研究对象,根据随机数字表法分为观察组(n=47)和对照组(n=46)。对照组采用本体感觉训练治疗,观察组在对照组基础上联合神经肌肉电刺激,2.均连续治疗12.。比较2.治疗后临床疗效、Cobb角、顶椎椎体旋转度、顶椎偏距。结果观察组总有效率为97.87%明显高于对照组的82.61%(P2.治疗12.后Cobb角明显低于治疗前,且观察组低于对照组(P2.治疗12.后顶椎旋转度明显低于治疗前,且观察组低于对照组(P2.治疗12.后顶椎偏距明显低于治疗前,且观察组低于对照组(P<0.05)。结论神经肌肉电刺激联合本体感觉训练治疗AIS临床效果显著,可明显改善患儿Cobb角、顶椎旋转度及顶椎偏距。

关键词：青少年特发性脊柱侧弯神经肌肉电刺激本体感觉训练

Highlights of mainstream solar cell efficiencies in 2.2.

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能源前沿:英文版 2023年第1期17卷 9-15页

作者： Wenzhong shen Yixin zhao Feng LIU Institute of Solar Energy and Key Laboratory of Artificial Structures and Quantum Control of the Ministry of EducationSchool of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China School of Environmental Science and Engineering and Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong UniversityShanghai 200240China School of Chemistry and Chemical Engineering and Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong UniversityShanghai 200240China

The world record power conversion efficiency(PCE)of both the single-junction silicon and perovskite/silicon tandem solar cells was broken in 2.2.,and the massproduction of the passivating contact and perovskite solar cells(PSCs)was also significantly developed in *** to the first viewpoint on the highest independently confirmed PCE of mainstream and emerging solar cells in 2.2.[1],this paper highlights the certified PCE in 2.2. of silicon,perovskite,and organic solar cells and analyzes the progress of each cell technology.

关键词： technology. perovskite mainstream

Highlights of mainstream solar cell efficiencies in 2.2.

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Frontiers in Energy 2022年第1期16卷 1-8页

作者： Wenzhong shen Yixin zhao Feng LIU Institute of Solar Energy and Key Laboratory of Artificial Structures and Quantum Control(Ministry of Education)School of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China School of Environmental Science and Engineering and Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong UniversityShanghai 200240China School of Chemistry and Chemical Engineering and Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong UniversityShanghai 200240China

Solar photovoltaic(PV)technology is expected to play a key role in global carbon *** global new installed solar PV capacity over the past 2. years has grown at a compound annual growth rate of approximately 40%,far outpacing other energy sources such as coal,oil,natural gas,and wind[1].The strong momentum of the PV industry comes from its rapidly decreased levelized cost of electricity due to technological improvement and large-scale application.

关键词： Solar momentum neutral

多发伤患者血清高迁移率族蛋白B1及可溶性髓样细胞触发受体-1水平变化及预后意义

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上海交通大学学报（医学版） 2024年第3期44卷 350-357页

作者：王桂杰杜传冲陆叶赵健沈勰金冬林耿佳财江苏省苏州市第九人民医院急诊医学科苏州215000

目的·检测多发伤患者不同时间点的血清高迁移率族蛋白B1(high mobility group box 1,HMGB1)及可溶性髓样细胞触发受体-1(soluble triggering receptor expressed on myeloid cell-1,sTREM-1)水平,并分析其与病情严重程度、并发症及预... 详细信息

目的·检测多发伤患者不同时间点的血清高迁移率族蛋白B1(high mobility group box 1,HMGB1)及可溶性髓样细胞触发受体-1(soluble triggering receptor expressed on myeloid cell-1,sTREM-1)水平,并分析其与病情严重程度、并发症及预后的相关性。方法·选取2.2.年12.至2.2.年12.在苏州市第九人民医院急诊科收治的多发伤患者92.,根据患者入院时的损伤严重程度评分将患者分为轻伤组(n=2.)、重伤组(n=58)、严重伤组(n=10);依据入院后是否合并多器官功能障碍综合征(multiple organ dysfunction syndrome,MODS)将患者分为MODS组(n=2.)和非MODS组(n=72.;根据创伤发生后2. d内结局将患者分为死亡组(n=13)和存活组(n=79)。检测患者入院后静脉血炎症因子指标。采用酶联免疫吸附试验(enzyme linked immunosorbent assay,ELISA)检测创伤发生后2. h、72.h及7 d的血清HMGB1、sTREM-1水平。分析不同分组间血清HMGB1、sTREM-1水平的差异,并采用多因素Logistic回归分析多发伤患者不良结局的影响因素。运用受试者工作特征(receiver operating characteristics,ROC)曲线评估HMGB1、sTREM-1对不良结局的预测价值。结果·重伤和严重伤组各时间点HMGB1、sTREM-1水平明显高于轻伤组(均P2.h和7 d的HMGB1水平及2. h和72.h的sTREM-1水平明显高于重伤组(均P1与sTREM-1水平呈正相关性(r=0.645,r=0.942.r=0.72.;均P2.h和7 d的HMGB1水平及2. h和72.h的sTREM-1水平明显高于非MODS组(均P2.h和7 d的HMGB1水平及2. h、72.h的sTREM-1水平明显高于存活组(均P1水平及入院时间、超敏C反应蛋白(hypersensitive C-reactive protein,hs-CRP)水平是多发伤患者不良结局的独立影响因素(均P1水平预测不良预后的曲线下面积为0.890,敏感度为83.5%,特异度为92.3%。结论·多发伤患者创伤发生后不同时间点HMGB1及sTREM-1水平与MODS及生存结局相关,且创伤发生后7 d的HMGB1水平是多发伤患者不良结局的独立影响因素。

关键词：多发伤高迁移率族蛋白B1 可溶性髓样细胞触发受体-1 预后

Coupling between Particle Shape and Long-Range Interaction in the High-Density Regime

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Chinese physics Letters 2020年第8期37卷 63-67页

作者： Can-can Zhou Hongchuan shen Hua tong Ning Xu Peng Tan State Key Laboratory of Surface physics and department of physics Fudan UniversityShanghai 200433China School of physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China CAS Key Laboratory of Soft Matter Chemistry Hefei National Laboratory for Physical Sciences at the Microscaleand Department of PhysicsUniversity of Science and Technology of ChinaHefei 230026China department of Fundamental Engineering Institute of Industrial ScienceUniversity of Tokyo4-6-1 KomabaMeguro-kuTokyo 153-8505Japan

We experimentally probe the coupling between particle shape and long-range interaction,using long-range interacting *** two typical space-filling polygons,square and triangle,we find two types of coupling modes that predominantly control the structure ***,the rotational ordering of squares brings a lattice deformation that produces a hexagonal-to-rhombic transition in the high density regime,whereas the alignment of triangles introduces a large geometric frustration that causes an order-to-disorder ***,the two coupling modes lead to small and large“internal roughness”of the two systems,and thus predominantly control their structure *** study thus provides a physical picture to the coupling between long-range interaction effect and short-range shape effect in the high-density regime unexplored before.

关键词： transition. coupling polygon

Benford's Law in Nuclear Structure physics

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Chinese physics Letters 2011年第3期28卷 43-46页

作者： JIANG Hui shen Jia-Jie zhao Yu-Min School of Arts and Sciences Shanghai Maritime UniversityShanghai 200135 Institute of Nuclear ParticleAstrophysics and CosmologyDepartment of PhysicsShanghai Jiao Tong UniversityShanghai 200240 Center of Theoretical Nuclear physics National Laboratory of Heavy Ion AcceleratorLanzhou 730000 CCAST World LaboratoryPO Box 8730Beijing 100190

We investigate Benford's law based on the 2.03 version of atomic mass *** is demonstrated that the first non-zero digit distribution functions for a number of experimental quantities are in reasonable agreement with those predicted by Benford's *** data that we investigate here include 3001 sets of Sp,3060 sets of Sn,2.43 sets of two-neutron separation energies S_(2.),2.2. sets of two-proton separation energies S_(2.),1643 sets ofβ^(+)-decay energies Q(β^(+)),12.3 sets ofβ^(-)-decay energies Q(β^(-)),2.95 sets of double,β^(-)-decay energies Q(ββ^(-)),and 2.11 sets of energies in electron-capture proton processes Q(εp).The first non-zero digits of these data favor the smaller ones in a logarithmic pattern.

关键词： decay separation digit

基于单细胞转录组测序对牙周炎小鼠脑膜生物学改变与认知障碍相关性的研究初探

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中华口腔医学杂志 2024年第6期59卷 595-603页

作者：江旖婷徐丽娜赵旭日沈慧邱澈何智妍周薇宋忠臣上海交通大学医学院附属第九人民医院牙周病科上海交通大学口腔医学院国家口腔医学中心国家口腔疾病临床医学研究中心上海市口腔医学重点实验室上海市口腔医学研究所上海200011 上海交通大学医学院附属第九人民医院口腔微生态与系统性疾病实验室上海交通大学口腔医学院国家口腔医学中心国家口腔疾病临床医学研究中心上海市口腔医学重点实验室上海市口腔医学研究所上海200011

目的运用单细胞转录组测序分析牙周炎小鼠脑膜的生物学改变,探讨牙周炎小鼠脑膜生物学改变与认知障碍的相关性。方法将30只C57BL/6小鼠按随机数字表法随机分为2.(每组15只),在对照组小鼠上颌双颊侧局部涂抹不含牙龈卟啉单胞菌(Pg)的2.... 详细信息

目的运用单细胞转录组测序分析牙周炎小鼠脑膜的生物学改变,探讨牙周炎小鼠脑膜生物学改变与认知障碍的相关性。方法将30只C57BL/6小鼠按随机数字表法随机分为2.(每组15只),在对照组小鼠上颌双颊侧局部涂抹不含牙龈卟啉单胞菌(Pg)的2.羧甲基纤维素(CMC),在实验组小鼠上颌双颊侧局部涂抹Pg W83和2.CMC的混合物,3次/周,持续16周。观察对照组和实验组小鼠上颌牙槽骨吸收情况、自主活动能力与认知功能的变化、大脑皮层中小胶质细胞和星形胶质细胞激活情况、检测小鼠脑膜和大脑内紧密连接蛋白Occludin mRNA表达情况。然后使用统一流形逼近与投影(UMAP)算法对单细胞转录组各细胞亚群数据进行降维整合处理。对内皮细胞差异基因进行基因本体(GO)和京都基因和基因组数据库(KEGG)富集分析,进一步采用实时荧光定量PCR(RT-qPCR)验证差异基因转录激活因子3(Atf3)、含载脂蛋白L域1(Apold1)的表达情况。结果亚甲蓝染色实验显示,实验组小鼠上颌颊、腭侧釉质牙骨质界到牙槽嵴顶的距离[分别为(185.60±17.60)、(2.6.90±13.37)μm]均显著大于对照组[分别为(135.33±9.57)、(163.05±14.98)μm](t=5.02.P=0.002.t=4.37,P=0.005)。旷场实验显示实验组小鼠的总路程和平均速度[(971.88±164.57)cm和(3.2.±0.55)cm/s]与对照组[(914.2.±2.8.81)cm和(3.05±0.93)cm/s]相比差异均无统计学意义(t=0.65,P=0.52.;t=0.65,P=0.52.)。新物体识别实验中实验组小鼠相对辨别指数[(48.02.16.92.%]显著低于对照组[(66.2.±17.90)%](t=2.40,P=0.02.)。Y迷宫实验显示,实验组小鼠的自发交替率[(50.99±14.17)%]显著低于对照组[(63.56±11.88)%](t=2.33,P=0.030)。免疫组化染色结果显示,实验组小鼠脑内小胶质细胞和星形胶质细胞被激活。RT-qPCR结果显示,实验组小鼠脑膜和大脑中紧密连接蛋白Occludin mRNA的表达(分别为0.61±0.10、0.64±0.2.)均显著低于对照组(分别为1.02.0.2.、1.04±0.31)(t=3.47,P=0.010;t=2.66,P=0.02.)。单细胞转录组测序显示,脑膜存在11种细胞类型,包括内皮细胞、成纤维细胞、免疫细胞等,其中内皮细胞占比最大[对照组为2..47%(1589/6004),实验组为2..2.%(807/3073)],是脑膜中最主要的细胞类型;实验组小鼠脑膜组织中粒细胞比例[11.65%(358/3073)]较对照组[5.56%(334/6004)]增加。进一步聚类分析内皮细胞,GO富集分析显示差异基因与血管生成、细胞黏附、细胞凋亡等有关;KEGG分析显示差异基因与白细胞介素-17信号通路、松弛素信号通路等相关。RT-qPCR显示,实验组小鼠脑膜组织中Atf3和Apold1 mRNA表达(分别为0.42.0.2.、0.54±0.2.)均显著低于对照组(分别为1.03±0.2.、1.02.0.2.)(t=3.88,P=0.005;t=3.02.P=0.017)。结论Pg W83慢性感染的牙周炎小鼠认知能力下降,存在神经炎症,屏障功能改变;单细胞转录组测序发现脑膜组织存在免疫细胞浸润,Atf3和Apold1基因表达下调,提示脑膜免疫和屏障功能的改变在牙周炎导致的认知障碍中发挥作用。

关键词：牙周炎紫单胞菌,龈认知障碍神经炎症单细胞转录组测序脑膜

原发性胸膜弥漫大B细胞淋巴瘤伴免疫性血小板减少症一例并文献复习

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白血病．淋巴瘤 2018年第4期27卷 238-242页

作者：吴文王黎沈杨赵维莅童建华上海交通大学医学院附属瑞金医院血液科 200025 上海交通大学医学院附属瑞金医院中心实验室 200025

目的探讨原发性胸膜弥漫大B细胞淋巴瘤（DLBCL）的临床特征、实验室检查及诊治经过，分析免疫性血小板减少症（ITP）与淋巴瘤的关系，以提高对该罕见病的诊断水平。方法分析上海交通大学医学院附属瑞金医院收治的1例原发性胸膜DLBCL伴IT... 详细信息

目的探讨原发性胸膜弥漫大B细胞淋巴瘤（DLBCL）的临床特征、实验室检查及诊治经过，分析免疫性血小板减少症（ITP）与淋巴瘤的关系，以提高对该罕见病的诊断水平。方法分析上海交通大学医学院附属瑞金医院收治的1例原发性胸膜DLBCL伴ITP患者的临床特点、诊治情况，并结合文献进行讨论。结果患者因反复胸闷气促6个月入院，完善相关检查（B型超声、胸部CT、PET-CT、胸腔积液穿刺等），临床主要特征仅发现胸腔积液，无其他部位病变，肝、脾、淋巴结均正常，胸腔积液病理诊断为DLBCL。患者既往诊断ITP30年。确诊后行R-CHOP方案化疗6次，中期评估胸腔积液完全吸收，疗效达完全缓解。结论原发性胸膜DLBCL较罕见，临床表现及影像学缺乏特异性，极易漏诊和误诊，确诊须依据组织病理学证据。ITP可先于淋巴瘤发生，也可以和淋巴瘤同时发生，少数患者可在罹患淋巴瘤的过程中发生ITP。

关键词：淋巴瘤大B-细胞弥漫性胸膜免疫性血小板减少症

Angle-Resolved Plasmonic Properties of Single Gold Nanorod Dimers

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Nano-Micro Letters 2014年第4期6卷 372-380页

作者： Jian Wu Xuxing Lu Qiannan Zhu Junwei zhao Qishun shen Li Zhan Weihai Ni department of physics and Astronomy Key Laboratory for Laser Plasmas (Ministry of Education) State Key Lab of Advanced Optical Communication Systems and NetworksShanghai Jiao Tong University Division of i-Lab Key Laboratory for Nano-Bio Interface Research & Collaborative Innovation Center of Suzhou Nano Science and Technology Suzhou Institute of Nano-Tech & Nano-Bionics Chinese Academy of Sciences

Through wet-chemical assembly methods, gold nanorods were placed close to each other and formed a dimer with a gap distance *1 nm, and hence degenerated plasmonic dipole modes of individual nanorods coupled together to produce hybridized bonding and antibonding resonance modes. Previous studies using a condenser for illumination result in averaged signals over all excitation angles. By exciting an individual dimer obliquely at different angles, we demonstrate that these two new resonance modes are highly tunable and sensitive to the angle between the excitation polarization and the dimer orientation, which follows cos2.u dependence. Moreover, for dimer structures with various structure angles, the resonance wavelengths as well as the refractive index sensitivities were found independent of the structure angle. Calculated angle-resolved plasmonic properties are in good agreement with the measurements. The assembled nanostructures investigated here are important for fundamental researches as well as potential applications when they are used as building blocks in plasmon-based optical and optoelectronic devices.

关键词： Plasmonics Gold nanorods Self-assembly