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Numerical Study on Viscous Fingering Using Electric Fields in a Hele-Shaw Cell

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Communications in Computational physics 2023年第2期33卷 399-424页

作者： Meng zhao Pedro Anjos John Lowengrub Wenjun Ying Shuwang Li Center forMathematical Sciences Huazhong University of Science and TechnologyWuhanHubei 430074China department of AppliedMathematics Illinois Institute of TechnologyChicagoIL 60616USA department of Mathematics University of California IrvineIrvineCA 92697USA School of Mathematical Sciences MOE-LSC and Institute of Natural SciencesShanghai Jiao Tong UniversityShanghai 200240China.

We investigate the nonlinear dynamics of amoving interface in aHele-Shaw cell subject to an in-plane applied electric *** develop a spectrally accurate numerical method for solving a coupled integral equation *** the stiffness due to the high order spatial derivatives can be removed using a small scale decomposition technique,the long-time simulation is still expensive since the evolving velocity of the interface drops dramatically as the interface *** remove this physically imposed stiffness by employing a rescaling scheme,which accelerates the slow dynamics and reduces the computational *** nonlinear results reveal that positive currents restrain finger ramification and promote the overall stabilization of *** the other hand,negative currents make the interface more unstable and lead to the formation of thin tail structures connecting the fingers and a small inner *** no fluid is injected,and a negative current is utilized,the interface tends to approach the origin and break up into several *** investigate the temporal evolution of the smallest distance between the interface and the origin and find that it obeys an algebraic law(t∗−t)b,where t∗is the estimated pinch-off time.

关键词： Hele-Shaw problem fingering instabilities electro-osmotic flow boundary integral method rescaling idea

Prevalence, clinical characteristics and outcome in patients with chronic heart failure and diabetes

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Chinese Medical Journal 2010年第6期123卷 646-650页

作者： SHI Chuan WANG Ling-jie HU Dan-feng LI Jin-ping ZHU Tian-qi SHAN Ying zhao Jian-rong ZHANG Feng-ru shen Wei-feng department of Cardiology Ruiiin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China department of Cardiology Huashan HospitalFudan University School of MedicineShanghai 200032China department of Cardiology Luwan HospitalShanghai 200025China

Background Chronic heart failure（CHF）and diabetes mellitus portend high morbidity and mortality because of an interrelated pathophysiologic *** large cohort study aimed to analyze the prevalence,clinicaI characteristics and long-term outcome of patients with CHF and *** A totaI of 1119 patients with NYHA functionaI class Ⅱ-Ⅳ and left ventricular ejection fraction（LVEF）〈45% between January 1995 and May 2009 were *** variables, biochemical and echocardiographic measurements were retrospectively reviewed,and composite major cardiac events （MCE） including death,headtransplantation, and refractory heart failure requiring multiple hospitalizations were *** The prevalence of CHF with diabetes was progressively increased with time （16.9% in 1995-1999;20.4% in 2000-2004,and 29.1% in 2005-2009）and age（1 8.5% in〈60 years,26.6% in 60-80 years,and 26.6% in〉80 years）.Compared with CHF patients without diabetes,those with diabetes had worse cardiac function,more abnormal biochemical *** higher *** with glucose-lowering agents significantly improved LVEF and decreased *** elevated serum HbA1c level was associated with large left ventricular end-systolic diameter （P〈0.05）,decreased LVEF（P〈0.01）and reduced survival（P〈0.05）.Multivariable Logistic regression analysis revealed that after adjustment for confounding factors,NYHA functional class（OR2.65,95%CI 1.14-6.16,P=0.024）and HbA1c level≥7%（OR2.78, 95%CI 1.00-7.68,P=0.049）were independent risk factors for adverse outcomes in CHF patients with *** Prevalence of CHF with diabetes was increasing during past decades,and patients with CHF and diabetes had worse clinical profiles and *** anti-CHF and diabetes therapies are needed to improve overall outcomes for these patients.

关键词： chronic heart failure diabetes mellitus prognosis medical treatment

经静脉注射的单链9型腺相关病毒介导基因在星形胶质细胞表达

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上海交通大学学报（医学版） 2020年第8期40卷 1036-1040页

作者：王晓丹杨钊沈帆霞上海交通大学医学院附属瑞金医院北院上海201801 美国加州大学旧金山分校麻醉与围术期医学系脑血管研究中心美国旧金山94110

目的·探讨静脉注射含低氧反应元件(hypoxia-responsive element,HRE)启动子的单链9型腺相关病毒(single-stranded adeno-associated virus serotype 9,ssAAV9)能否介导LacZ基因在脑缺血区表达,及其可转染的脑细胞类型。方法·建立永久性左侧远端大脑中动脉闭塞(distal middle cerebral artery occlusion,dMCAO)小鼠模型,模型建立1 d和5 d后检测脑缺血区中低氧诱导因子-1(hypoxia-inducible factor-1,HIF-1)的表达。dMCAO模型建立1 h经颈静脉注射AAV9-H9LacZ载体,注射5 d后X-gal染色检测脑缺血区和肝组织中LacZ基因编码蛋白β-半乳糖苷酶(β-galactosidase,β-gal)的表达,免疫荧光双染色检测β-gal在星形胶质细胞、神经元及血管内皮细胞内的表达。结果·dMCAO模型建立1 d和5 d后小鼠缺血病灶局部HIF-1表达增高。β-gal主要在AAV9-H9LacZ注射小鼠的缺血半暗带区表达,其肝脏组织无β-gal阳性表达。脑缺血区β-gal主要与胶质细胞原纤维酸性蛋白共表达,少量β-gal与神经元特异核蛋白共表达。结论·经静脉注射的ssAAV9主要介导基因在脑缺血区星形胶质细胞表达。HRE能有效控制LacZ基因主要在脑缺血区表达。

关键词： 9型腺相关病毒脑缺血低氧反应元件星形胶质细胞

Fe稳固的FeOOH@NiOOH电催化剂的大电流极化设计与析氧研究

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Chinese Journal of Catalysis 2024年第7期62卷 254-264页

作者：吕青芸张伟伟龙志鹏王建涛邹星礼任伟侯龙鲁雄刚赵玉峰余兴李喜上海大学先进特种钢国家重点实验室上海200444 上海交通大学上海高温先进材料及精密成形技术重点实验室上海200240 上海大学量子分子结构国际中心和材料基因组工程研究院上海200444 上海大学可持续能源研究所和化学系上海200444

电解水技术是制取高纯度氢气的有效途径,为传统的氢气生产提供了一种可持续的替代方案.其中,开发性能优异的电催化材料是降低电解水制氢成本的关键.析氧反应(OER)由于涉及多个电子转移而导致的动力学缓慢,是克服高过电位的主要挑战.镍... 详细信息

电解水技术是制取高纯度氢气的有效途径,为传统的氢气生产提供了一种可持续的替代方案.其中,开发性能优异的电催化材料是降低电解水制氢成本的关键.析氧反应(OER)由于涉及多个电子转移而导致的动力学缓慢,是克服高过电位的主要挑战.镍铁羟基/氢氧化物(NiFe(oxy)hydroxides)是近期研究的热点,其在碱性条件下具有极低的OER过电位,部分材料性能甚至超过了贵金属基催化剂,如IrO_(2)和RuO_(2).然而,NiFe(oxy)hydroxides的长期催化稳定性,尤其是在大电流下的长期催化稳定性,成为限制其实际应用的主要问题,这主要是由于铁元素的严重流失导致的.因此,如何有效控制和利用电化学溶解/沉积动力学成为稳定铁位点的关键.为克服该挑战,本文提出了一种大电流极化重构方法来固定活性铁位点.通过在大电流(1.5 A cm^(-2))下对材料进行表面快速极化重构,成功制备了FeOOH@NiOOH(eFNO_(L))电催化剂.eFNO_(L)不仅具有稳定的铁位点,还暴露出高指数晶面,因此eFNO_(L)同时展现出较好的OER催化活性和稳定性.同时,密度泛函理论计算结果表明,与具有低指数晶面的FeNiOOH相比,大电流极化工程制备的分相eFNO_(L)对铁位点表现出更高的结合能,可以有效抑制OER过程中的铁流失,且高指数晶面在改变速率决定步骤和减少吸附能垒上具有更大的优势.电化学测试结果表明,经过优化后的eFNO_(L)催化剂在产生100和500 mA cm^(-2)大电流密度仅需234和27 mV的过电位,并且具有较小的Tafel斜率(35.2 mV dec^(-1)).由于铁位点结合能的提高,eFNO_(L)催化剂在500 mA cm^(-2)的电流密度下能够稳定催化超过100 h,且仅有1.5%的性能衰减,优于近期报道的大多数镍铁基OER催化剂.综上,本文为开发高活性和高稳定性能的催化剂提供了一种有效的大电流电化学重构策略,在电解水制氢领域实现其工业化的大规模应用方面显示出巨大潜力,有望降低可持续电解水制氢成本.

关键词：析氧反应 FeOOH@NiOOH 大电流极化重构高指数晶面铁位点固定

Spontaneous low-temperature crystallization of α-FAPbI3 for highly efficient perovskite solar cells

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Science Bulletin 2019年第21期64卷 1608-1616页

作者： Taiyang Zhang Qiaoling Xu Feng Xu Yuhao Fu Yong Wang Yanfa Yan Lijun Zhang Yixin zhao School of Environmental Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Key Laboratory of Automobile Materials Ministry of EducationSchool of Materials Science and EngineeringJilin UniversityChangchun 130012China department of physics and Astronomy University of ToledoToledoOH 43606USA State Key Laboratory of Superhard Materials Jilin UniversityChangchun J30012China

Formamidinium lead triiodide(HC(NH2)2PbI3 or FAPbI3)is a promising light absorber for high-efficiency perovskite solar cells because of its superior light absorption range and thermal stability to CH3NH3PbI3(MAPbI3).Unfortunately,it is difficult to fabricate high-quality FAPbI3 thin films to surpass the MAPbI3-based cells due to easily forming unwanted but more stable yellow d-phase and thus requiring high annealing-temperature for wanted photovoltaic-active black ***,we reported a novel low-temperature fabrication of highly crystallized a-FAPbI3 film exhibiting uniaxial-oriented nature with large grain sizes up to 2 ***-principles energetic calculations predicted that this novel deposition should be ascribed to the formation of a high-energy metastable two-dimensional(2D)intermediate of MAFAPbI3 Cl followed by a spontaneous conversion to *** ions exchange reaction during this MAFAPbI3 Cl-FAPbI3 conversion account for the perovskite film uniaxial-oriented grown along the(111)*** large-grain and uniaxial-oriented grown a-FAPbI3 based solar cells exhibited an efficiency up to 20.4%accompanying with low density-voltage(J-V)hysteresis and high stability.

关键词： Perovskite solar cells Spontaneous crystallization FAPbI3 Two-dimensional (2D) perovskites

A sample of galaxy pairs identified from the LAMOST spectral survey and the Sloan Digital Sky Survey

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Research in Astronomy and Astrophysics 2016年第3期16卷 63-72页

作者： Shi-Yin shen Maria Argudo-Femandez Li Chen Xiao-Yan Chen Shuai Feng Jin-Liang Hou Yong-Hui Hou Peng Jiang Yi-Peng Jing Xu Kong A-Li Luo Zhi-Jian Luo Zheng-Yi Shao Ting-Gui Wang Wen-Ting Wang Yue-Fei Wang Hong Wu Xue-Bing Wu Hai-Feng Yang Ming Yang Fang-Ting Yuan Hai-Long Yuan Hao-tong Zhang Jian-Nan Zhang Yong Zhang Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Key Lab for Astrophysics Shanghai 200234China National Astronomical Observatories Chinese Academy of SciencesBeijing 100012China university of Chinese Academy of Sciences Beijing 100049China Nanjing Institute of Astronomical Optics&Technology National Astronomical ObservatoriesChinese Academy of SciencesNanjing 210042China university of Science and Technology of china Hefei 230026China department of physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Institute for Computational Cosmology University of DurhamSouth RoadDurhamDH1 3LEUK department of Astronomy Peking UniversityBeijing 100871China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China

A small fraction （〈 10%） of the SDSS main galaxy （MG） sample has not been targeted with spectroscopy due to the effect of fiber collisions. These galaxies have been compiled into the input catalog of the LAMOST ExtraGAlactic Surveys and named the complementary galaxy sample. In this paper, we introduce this project and status of the spectroscopies associated with the complementary galaxies in the first two years of the LAMOST spectral survey （till Sep. of 2014）. Moreover, we present a sample of 1102 galaxy pairs identified from the LAMOST complementary galaxies and SDSS MGs, which are defined as two members that have a projected distance smaller than 100 h^-01kpc and a recessional velocity difference smaller than 500 km s-1. Compared with galaxy pairs that are only selected from SDSS, the LAMOST- SDSS pairs have the advantages of not being biased toward large separations and therefore act as a useful supplement in statistical studies of galaxy interaction and galaxy merging.

关键词： galaxies: interactions -- galaxies: groups: general

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成人嗜血细胞综合征19例临床分析

上海交通大学学报（医学版） 2010年第10期30卷 1300-1302页

作者：赵明哲赵维莅沈志祥上海交通大学医学院附属瑞金医院血液科上海200025 浙江省金华市中心医院血液科金华321000

目的探讨成人嗜血细胞综合征(HPS)的临床特点。方法对2005年1月—2009年1月在上海交通大学医学院附属瑞金医院血液科就诊的19例成人HPS患者的临床资料进行回顾性分析。结果 19例患者初治时均表现为高热、肝脾肿大、凝血功能异常、血像... 详细信息

目的探讨成人嗜血细胞综合征(HPS)的临床特点。方法对2005年1月—2009年1月在上海交通大学医学院附属瑞金医院血液科就诊的19例成人HPS患者的临床资料进行回顾性分析。结果 19例患者初治时均表现为高热、肝脾肿大、凝血功能异常、血像三系或二系受累。10例(52.6%)最终确诊为非霍奇金淋巴瘤,2例(10.5%)为感染,1例(5.3%)为急性淋巴细胞白血病,6例(31.6%)原因不明。随访中死亡14例,存活1例(至今已6个月),4例失访;生存时间为2～6个月(中位生存时间3个月)。结论 HPS为罕见的致死性疾病,成人更为少见;临床表现复杂,常伴有多脏器受损的表现,病情凶险,进展迅速;预后大多不良,发病机制和治疗手段有待进一步研究。

关键词：嗜血细胞综合征发病机制治疗预后

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盘点气候风险机遇,展望健康繁荣未来

科学通报 2024年第27期69卷 4005-4011页

作者：张诗卉张弛蔡闻佳白玉琪 Max Callaghan 常楠陈彬陈慧琪程亮亮戴瀚程代鑫范维澄房小怡高仝耿阳关大博胡艺馨华峻翊黄存瑞黄弘黄建斌黄小猛纪思翰蒋俏蕾姜晓朋 Gregor Kiesewetter 李湉湉梁璐林波荣林华亮刘欢刘起勇刘小波刘钊刘竹刘昱甫陆波鲁晨曦罗震宇马伟米志付任超 Marina Romanello 沈鉴翔苏婧孙语泽孙昕璐汤绪 Maria Walawender 王灿王情汪蕊 Laura Warnecke 魏汪宇文三妹谢杨熊辉徐冰颜钰杨秀姚芳虹俞乐袁嘉灿曾仪娉张镜张璐张锐张尚辰张少辉赵梦真郑大山周浩周景博周子乔罗勇宫鹏清华大学地球系统科学系北京100084 北京理工大学管理学院北京100081 Mercator Research Institute on Global Commons and Climate Change Mercator Research Institute on Global Commons and Climate ChangeBerlin 10829Germany 南京医科大学公共卫生学院南京211166 北京师范大学环境学院北京100875 中山大学公共卫生学院广州510080 北京大学环境科学与工程学院北京100871 清华大学公共安全研究所北京100084 清华大学工程物理系北京100084 中国气象科学研究院气象影响与风险研究中心北京100086 山东师范大学商学院济南250013 清华大学建筑学院北京100084 南方科技大学统计与数据科学系深圳518055 中国海洋大学国际事务与公共管理学院青岛266003 清华大学万科公共卫生学院北京100084 清华大学新闻与传播学院北京100084 世界卫生组织驻华代表处北京100600 Pollution Management Research Group EnergyClimateand Environment ProgramInternational Institute for Applied Systems Analysis(IIASA)Laxenburg 1-A-2361Austria 中国疾病预防控制中心环境与健康相关产品安全所环境健康风险评估室北京102206 department of Landscape Architecture&Environmental Planning University of CaliforniaBerkeley CA 94607USA 清华大学环境学院北京100084 中国疾病预防控制中心传染病预防控制所传染病预防控制国家重点实验室北京102206 北京经济管理职业学院临空经济管理学院北京100102 中国气象局国家气候中心北京100081 Geography College of Life and Environmental SciencesUniversity of ExeterExeter EX12LUUK 山东大学齐鲁医学院公共卫生学院流行病学系济南250002 The Bartlett School of Sustainable Construction University College LondonLondon WC1H 0ALUK 香港大学建筑学院中国香港999077 Institute for Global Health University College LondonLondon WC1H 0ALUK 清华大学人文学院北京100084 复旦大学大气与海洋系/大气科学研究院上海200438 复旦大学极端天气/气候事件与人体健康风险互联和治理国际卓越中心上海200438 北京航空航天大学经济与管理学院北京100083 香港科技大学计算机科学与工程系广州511453 清华大学气候变化与可持续发展研究院北京100084 北京大学体育教研部北京100871 清华大学苏世民学院北京100084 清华大学城市治理与可持续发展研究院北京100084 百度研究院北京100091 香港大学地球科学系和地理系中国香港999077

气候变化带来的健康风险与日俱增,煤炭消费及相关碳排放量的反弹,再度敲响了中国气候变化警钟.2022年,中国面临了严峻的气候挑战.极端天气事件发生的频率和强度不断上升,许多地区气温纪录屡创新高,全国平均气温攀升至历史第二高位,同时... 详细信息

气候变化带来的健康风险与日俱增,煤炭消费及相关碳排放量的反弹,再度敲响了中国气候变化警钟.2022年,中国面临了严峻的气候挑战.极端天气事件发生的频率和强度不断上升,许多地区气温纪录屡创新高,全国平均气温攀升至历史第二高位,同时降水量自2012年以来创新低,南方地区遭遇夏秋连旱,而湖南和东北地区则出现了极端降雨和洪涝灾害.采取及时、充分的措施不仅能减轻气候变化对健康的影响,还将保护基础设施不被极端天气破坏.

关键词：煤炭消费极端天气事件基础设施气候变化极端降雨碳排放量气候风险盘点

Advantage of oncological outcome of robotic-assisted pancreatoduodenectomy (RPD) in stage I pancreatic ductal adenocarcinomas (PDAC)

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胰腺病学杂志(英文) 2022年第3期05卷 125-131页

作者： Li Jingfeng zhao Shulin Jin Jiabin Shi Yusheng Weng Yuanchi Chen Mengmin Chen Hao Xu Zhiwei Deng Xiaxing shen Baiyong Peng Chenghong department of General Surgery Pancreatic Disease Center 3. Ruijin Hospital 4. shanghai jiao tong university School of Medicine 5. shanghai 6. china

Background: Robotic-assisted pancreatoduodenectomy (RPD) has been widely performed in the treatment of pancreatic tumors. The oncologic outcome in the early stage of pancreatic ductal adenocarcinomas (PDAC) operated by RPD has not been ***: Clinical data of pathology confirmed stage I PDAC from January 2015 to December 2020 in Ruijin hospital, shanghai jiao tong university School of Medicine was collected and retrospectively analyzed. Patients were divided into the open pancreaticoduodenectomy (OPD) group and the RPD group. Clinicopathological data and prognosis data were compared and ***: A total of 426 patients were enrolled in this study, including 342 patients in the OPD group and 84 patients in the RPD group. The baseline characteristics of both groups were equivalent. Incidence of R1 resection was significantly lower in RPD group (3 [3.6%] vs 40 [11.7%],P = .044). RPD group was associated with better disease-free survival (DFS) and overall survival (OS) (DFS: Haszard Ratio [HR]: 0.681, 95% confidence interval [CI]: 0.491-0.945,P = .022; OS: HR: 0.667, 95% CI: 0.478-0.932,P = .017). T2 stage was associated with poor DFS and OS (DFS: HR: 1.471, 95% CI: 1.092-1.981,P = .011; OS: HR: 1.616, 95% CI: 1.209-2.160,P = .035). R1 resection was associated with poor OS (HR: 1.483, 95% CI: 1.028-2.140,P = .035) while adjuvant therapy was associated with better OS (HR: 0.589, 95% CI: 0.452-0.766,P 1). Kaplan-Meier estimate showed significantly longer DFS and OS in RPD group (DFS:P = .004; OS:P = .009).Conclusion: For stage I PDAC patients, RPD surgery achieved higher R0 resection rates and better DFS and OS. T1 stage was associated with better DFS. R0 resection and adjuvant therapy were the accesses to better OS.

关键词： DFS early stage PDAC oncological outcome OS RPD