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Chemical Research in Chinese Universities 2007年第5期23卷 558-561页

作者： WANG Hua ZENG Hong-bin YANG Shao-juan gao shen HUANG Yi-bing HOU Rui-zhen ZHAO Mi-feng XU Li ZHANG Xue-zhong　 Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education Jilin University Changchun 130021 P. R. China China-Japan Union Hospital of Jilin University Changchun 130033 P. R. China

The tripeptide,Arg-Gly-Asp（RGD）motif is an integrin-recognition site found in adhesive proteins present in extracellular matrices（ECM）and in the ***-8 cells were treated with cellular adhesion tripeptide RGD at various *** assay was performed to examine the growth and proliferation of HCT-8 cells after treatment with RGD for 48 *** and Eosin（HE）staining and electromicroscope were used to observe the morphology of apoptotic *** and flow cytometry were also used to analyze the HCT-8 *** adhesion tripeptide RGD significantly inhibits the growth and proliferation of HCT-8 cells in a dose-dependent manner and induces apoptosis of *** results indicate that cellular adhesion tripeptide RGD inhibits the growth and proli-feration of tumor HCT-8 cell,probably by the aid of inducing apoptosis of HCT-8 cell.

关键词： RGD HCT-8 cell Cell apoptosis

Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease

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Chronic Diseases and Translational Medicine 2017年第2期3卷 -页

作者： shen gao Jing Liu Department of Epidemiology Beijing An Zhen HospitalCapital Medical UniversityBeijing Institute of HeartLung and Blood Vessel DiseasesBeijing 100029China

Atherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease (CHD), ischemic stroke and other atherosclerotic cardiovascular disease (ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized low-density lipoprotein (ox-LDL) in the progression of ASCVD. This article briefly reviews the atherogenic mechanism of ox-LDL, the methods of measuring ox-LDL in the circulation, effect of medical therapy and life-style modification on ox-LDL level, and the association between circulating ox-LDL and atherosclerosis, including clinical ASCVD events and subclinical atherosclerosis, in observational studies.

关键词： Oxidized low density lipoprotein Atherosclerosis Cardiovascular disease Subclinical atherosclerosis Review

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庄子对墨家的批驳及其原因论析

齐鲁学刊 2013年第2期 29-33页

作者：高深淮北师范大学文学院安徽淮北235000

庄子对墨家的批评和驳难主要集中在责其"淆是非"、"乱人性"、"毁道德"、"贼天下"四个方面。庄子将墨家的辩论视为无用的"骈拇枝指",并指责其混淆是非,扰乱人心。他认为墨家宣扬仁义本身就是对"道"的损害,徒然为乱天下。然而,墨家主张上... 详细信息

庄子对墨家的批评和驳难主要集中在责其"淆是非"、"乱人性"、"毁道德"、"贼天下"四个方面。庄子将墨家的辩论视为无用的"骈拇枝指",并指责其混淆是非,扰乱人心。他认为墨家宣扬仁义本身就是对"道"的损害,徒然为乱天下。然而,墨家主张上同于"天"、以"天"立教,与道家主张上同于"道"、以"道"立教本质相同。庄子批驳墨家的原因,从表面上看,是墨家"天志"、"明鬼"、"非命"、"尚同"、"法仪"诸说没有引起庄子的注意,其根本原因则在于墨家的说教不符合道家自然无为的旨趣。墨家虽然强调"天"、"人"之际,但因"道"性"无为",墨家对"天志"等的论说并不为庄子所承认。庄子以其自然之"道"对墨家的仁义说教和辩论予以批驳,自然也难逃"隐于小成"的命运。

关键词：庄子墨学批驳原因

All-solid-state ultraviolet laser based on frequency doubling in an external ring cavity

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Optoelectronics Letters 2007年第6期3卷 448-450页

作者： shen gao WANG Bao-shan TAN Hui-ming PENG Ji-ying FU Xi-hong ZHAO Yu-huan Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun 130033 China Graduate School of the Chinese Academy of Sciences Beijing 100039 China

An all-solid-state ultraviolet laser based on frequency doubling in an external ring cavity with low input pump power is reported. Both second harmonic generation （SHG） and fourth harmonic generation （PRIG） occurred in an external threemirrors ring cavity. The need for impedance matching of this cavity to the input radiation was eliminated and the cavity adaptation was simplified, because the mirrors were not highly reflecting at 1064 nm and the cavity resonates only at 532 rim. Experiment results demonstrate that the conversion efficiency of this external cavity is higher than that of the singlepass condition.

关键词：固体激光器外部环空腔频率重叠

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避蚊胺微球载药量的HPLC测定

中国医药工业杂志 2005年第9期36卷 572-573页

作者：高静高申第二军医大学药学院药剂学教研室上海200433

A HPLC method for determination of N,N-diethyl-m-toluamide(DEET)loaded in microspheres was established. An ODS column was used with the mobile phase of methanol-water(65∶35)at the detection wavelength of 210nm. The calibration curve was linear in the range of 10 - 150μg/ml, and the detection limit was 4ng. The average recovery was 99.8% with RSD of 0.65%. The average drug loading of three batches of DEET microspheres were 16.1%, 16.3% and 17.7%.

关键词： HPLC测定避蚊胺药量溶剂挥发法球载心血管疾病乙基纤维素 HPLC法吸血昆虫

Entropy of Dilatonic Black Hole due to Arbitrary Spin Fields

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Chinese Journal of Astronomy and Astrophysics 2001年第4期1卷 357-364页

作者： You-Gen shen and Chang-Jun gao (Shanghai Astronomical Observatory, Chinese Academy of Sciences, Shanghai 200030 National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 Institute of Theoretical Physics, Chinese Academy of Scienc Institute of Theoretical Physics Chinese Academy of Sciences Beijing 100080

Using the membrane model based on the brick-wall model, we calculate the free energy and entropy of dilatonic black hole due to arbitrary spin fields. The result shows that the entropy of scalar field and the entropy ... 详细信息

关键词： black hole physics - entropy - spin

Overexpression of decoy receptor 3 in hepatocellular carcinoma and its association with resistance to Fas ligand-mediated apoptosis

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World Journal of Gastroenterology 2005年第38期11卷 5926-5930页

作者： Hong-Wei shen Shun-Liang gao Yu-Lian Wu Shu-You Peng Department of Surgery 2^nd Affiliated Hospital of Medical CollegeZhejiang University Hangzhou 310009 Zhejiang Province China

AIM： To characterize the expression and genomic amplification of decoy receptor 3 （DcR3） in hepatocellular carcinoma （HCC） and to evaluate the role of DcR3 in apoptosis.METHODS： We examined 48 cases of HCC for DcR3 expression by RT-PCR and DcR3 gene amplification by quantitative genomic PCR. DcR3 protein was detected by immunohistochemistry. Terminal deoxynucleotidyl transferase-mediated dUTP digoxigenin nick and labeling （TUNEL） was used to identify the apoptosis cells in tissues. Primary hepatoma cell culture and MTT test were used to evaluate the protection against FasL- and chemicalinduced apoptosis by DcR3 expression. RESULTS： DcR3 mRNA overexpression was detected in 60% HCC （29/48） patients. The occurrence of HCC was not associated with amplification of the gene. One sample base substitution was found in three sites as a sequence in Genbank. The expression of DcR3 in HCC was associated with the apoptotic index （0.067±0.04 vs 0.209±0.12, P〈0. 01）, size of mass, stage, and infiltration or metastasis （41.2% vs71.0%, 40% vs75%, 51.8% vs84.6%, P〈0. 05）. DcR3 expression could protect hepatoma cells against apoptosis induced by FasL, but not by chemicals. CONCLUSION： These data suggest that in addition to gene amplification there may be another mechanism underlying DcR3 overexpression. The effect of overexpression of DcR3 on the apoptosis of cancer cells may have direct therapeutic implications for the management of HCC.

关键词： DcR3 Hepatocellular carcinoma Apoptosis

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公路工程新旧估算指标对比研究

建筑经济 2020年第3期41卷 49-55页

作者：高屾天津市市政工程设计研究院天津300392

通过选取近年来不同地区的9个工程项目,用新颁布实施的《公路工程建设项目投资估算编制办法》(JTG 3820-2018)及《公路工程估算指标》(JTG/T 3821-2018)编制投资估算,对比分析新旧估算的造价差异。研究结果表明:桥隧比较高的项目,建安... 详细信息

通过选取近年来不同地区的9个工程项目,用新颁布实施的《公路工程建设项目投资估算编制办法》(JTG 3820-2018)及《公路工程估算指标》(JTG/T 3821-2018)编制投资估算,对比分析新旧估算的造价差异。研究结果表明:桥隧比较高的项目,建安费的增减幅度也较大,反之新旧估算的变化幅度较小;新估算建安费中人工消耗量和多数主要机械的台班消耗量都比旧估算大幅降低,且新估算的费率费用也比旧估算的费率费用下降较大;新估算中工程建设其他费用普遍降低,且降幅较大。

关键词：公路工程估算指标投资估算对比分析造价差异

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“营改增”对公路项目财务评价的影响分析

建筑经济 2022年第3期43卷 82-89页

作者：高屾天津市政工程设计研究总院有限公司天津300392

"营改增"的全面实施,给出了在公路项目财务评价中对于增值税的处理方法。结合工程实例分析了"营改增"对公路项目财务评价指标的影响。实例分析表明,在"营改增"后,由于运营期销项税额相比营业税时期明显增加,再加上进项税额的抵扣不足,... 详细信息

"营改增"的全面实施,给出了在公路项目财务评价中对于增值税的处理方法。结合工程实例分析了"营改增"对公路项目财务评价指标的影响。实例分析表明,在"营改增"后,由于运营期销项税额相比营业税时期明显增加,再加上进项税额的抵扣不足,使项目在运营期的实际税负反而增加,内部收益率指标降低。今后应扩展增值税的抵扣范围,从而有效降低企业税负,改善公路项目的财务评价指标。

关键词：营改增公路项目财务评价内部收益率

采用空时分组编码的动态分组加权合作频谱感知方案

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西安交通大学学报 2014年第8期48卷 23-28,66页

作者：王兵白智全董培浩高深高鹏山东大学信息科学与工程学院济南250100 四川理工学院企业信息化与物联网测控技术四川省高校重点实验室四川自贡643000

针对认知无线电网络中存在的非理想反馈信道与用户间信道使合作频谱感知算法难以有效提高频谱检测性能的问题,提出了一种基于空时分组编码的动态分组加权合作频谱感知(DCWCSS)方案。首先将所有未分组认知用户中具有最高用户间信道平均... 详细信息

针对认知无线电网络中存在的非理想反馈信道与用户间信道使合作频谱感知算法难以有效提高频谱检测性能的问题,提出了一种基于空时分组编码的动态分组加权合作频谱感知(DCWCSS)方案。首先将所有未分组认知用户中具有最高用户间信道平均信噪比的两个用户分为一组,并依此将剩余用户进行两两分组,然后根据各认知用户检测结果对系统检测性能的贡献对认知用户进行加权,赋予不同权重,最后采用空时分组编码(STBC)方案将用户检测结果传输给基站进行判决。DC-WCSS方案可依据用户间信道平均信噪比进行动态分组,并根据认知用户检测结果的可靠性设置用户权重,能有效降低反馈阶段的误码率,从而提高系统检测性能。仿真结果表明,与基于传输分集的合作频谱感知方案相比,在虚警概率为0.3时,DC-WCSS方案的一次加权和二次加权后的系统检测概率可分别提升至少20%和30%。

关键词：认知无线电频谱感知空时分组编码动态分组加权