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工程与科学中的计算机建模(英文) 2024年第1期138卷 221-243页

作者： feng shen Yang Zhao Bingyi Li Kai Wu School of Civil Engineering Suzhou University of Science and TechnologySuzhou215011China R&D Department Suzhou Jcon Greenbuild Fabricated Co.Ltd.Suzhou215004China

The calculation of the factor of safety(FOS)is an important means of slope evaluation.This paper proposed an improved double strength reductionmethod(DRM)to analyze the safety of layered slopes.The physical properties of different soil layers of the slopes are different,so the single coefficient strength reduction method(SRM)is not enough to reflect the actual critical state of the slopes.Considering that the water content of the soil in the natural state is the main factor for the strength of the soil,the attenuation law of shear strength of clayey soil changing with water content is fitted.This paper also establishes the functional relationship between different reduction coefficients.Then,a USDFLD subroutine is programmed using the secondary development function of finite element software.Controlling the relationship between field variables and calculation time realizes double strength reduction applicable to the layered slope.Finally,by comparing the calculation results of different examples,it is proved that the stress and displacement distribution of the critical slope state obtained by the improved method is more realistic,and the calculated safety factor is more reliable.The newly proposedmethod considers the difference of intensity attenuation between different soil layers under natural conditions and avoids the disadvantage of the strength reduction method with uniform parameters,which provides a new idea and method for stability analysis of layered and complex slopes.

关键词： Double strength reduction slopes stability water content factor of safety numerical methods

The Analysis of the Correlation between SPT and CPT Based on CNN-GA and Liquefaction Discrimination Research

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1159-1182页

作者： Ruihan Bai feng shen Zihao Zhao Zhiping Zhang Qisi Yu Key Laboratory of the Ministry of Education for Geomechanics and Embankment Engineering College of Civil and Transportation EngineeringHohai UniversityNanjing210098China School of Civil Engineering Suzhou University of Science and TechnologySuzhou215011China School of Civil Engineering Shenyang Jianzhu UniversityShenyang110168China College of Civil Engineering Tongji UniversityShanghai200092China

The objective of this study is to investigate themethods for soil liquefaction discrimination. Typically, predicting soilliquefaction potential involves conducting the standard penetration test (SPT), which requires field testing and canbe time-consuming and labor-intensive. In contrast, the cone penetration test (CPT) provides a more convenientmethod and offers detailed and continuous information about soil layers. In this study, the feature matrix based onCPT data is proposed to predict the standard penetration test blow count N. The featurematrix comprises the CPTcharacteristic parameters at specific depths, such as tip resistance qc, sleeve resistance f s, and depth H. To fuse thefeatures on the matrix, the convolutional neural network (CNN) is employed for feature extraction. Additionally,Genetic Algorithm (GA) is utilized to obtain the best combination of convolutional kernels and the number ofneurons. The study evaluated the robustness of the proposed model using multiple engineering field data sets.Results demonstrated that the proposed model outperformed conventional methods in predicting N values forvarious soil categories, including sandy silt, silty sand, and clayey silt. Finally, the proposed model was employedfor liquefaction discrimination. The liquefaction discrimination based on the predicted N values was comparedwith the measured N values, and the results showed that the discrimination results were in 75% agreement. Thestudy has important practical application value for foundation liquefaction engineering. Also, the novel methodadopted in this research provides new ideas and methods for research in related fields, which is of great academicsignificance.

关键词： CNN liquefaction discrimination SPT CPT

Predictive performance of the variation rate of the driving pressure on the outcome of invasive mechanical ventilation in patients with acute respiratory distress syndrome

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Chinese Journal of Traumatology 2024年第2期27卷 107-113页

作者： Hui-Dan Jing Jun-Ying Tian Wei Li Bing-Ling He Hong-Chao Li Fu-Xia Jian Cui Shang feng shen Department of Intensive Care Unit The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550004China Department of Intensive Care Unit Army Medical Center of PLAChongqing400042China College of Foreign Languges Chongqing Medical UniversityChongqing400016China

Purpose:To assess the value of the driving pressure variation rate(ΔP%)in predicting the outcome of weaning from invasive mechanical ventilation in patients with acute respiratory distress syndrome.Methods:In this case-control study,a total of 35 patients with moderate-severe acute respiratory distress syndrome were admitted to the intensive care unit between January 2022 and December 2022 and received invasive mechanical ventilation for at least 48 h were enrolled.Patients were divided into successful weaning group and failed weaning group depending on whether they could be removed from ventilator support within 14 days.Outcome measures including driving pressure,PaO2:FiO2,and positive end-expiratory pressure,etc.were assessed every 24 h from day 0 to day 14 until successful weaning was achieved.The measurement data of non-normal distribution were presented as median(Q1,Q3),and the differences between groups were compared by Wilcoxon rank sum test.And categorical data use the Chi-square test or Fisher's exact test to compare.The predictive value ofΔP%in predicting the outcome of weaning from the ventilator was analyzed using receiver operating characteristic curves.Results:Of the total 35 patients included in the study,17 were successful vs.18 failed in weaning from a ventilator after 14 days of mechanical ventilation.The cut-off values of the medianΔP%measured by Operator 1 vs.Operator 2 in the first 4 days were≥4.17%and 4.55%,respectively(p<0.001),with the area under curve of 0.804(sensitivity of 88.2%,specificity of 64.7%)and 0.770(sensitivity of 88.2%,specificity of 64.7%),respectively.There was a significant difference in mechanical ventilation duration between the successful weaning group and the failure weaning group(8(6,13)vs.12(7.5,17.3),p=0.043).The incidence of ventilator-associated pneumonia in the successful weaning group was significantly lower than in the failed weaning group(0.2‰vs.2.3‰,p=0.001).There was a significant difference noted between these 2 groups in the 28-day mortality(11.8%vs.66.7%,

关键词： Driving pressure Driving pressure variation rate Acute respiratory distress syndrome Mechanical ventilation

Topological edge and corner states of valley photonic crystals with zipper-like boundary conditions

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Chinese Physics B 2024年第4期33卷 480-491页

作者：沈云峰许孝芳孙铭周文佶常雅箐 School of Mechanical Engineering Jiangsu UniversityZhenjiang 212000China School of Optical and Electronic Information Suzhou City University&Suzhou Key Laboratory of BiophotonicsSuzhou 215104China

We present a stable valley photonic crystal(VPC)unit cell with C_(3v)symmetric quasi-ring-shaped dielectric columns and realize its topological phase transition by breaking mirror symmetry.Based on this unit cell structure,topological edge states(TESs)and topological corner states(TCSs)are realized.We obtain a new type of wave transmission mode based on photonic crystal zipper-like boundaries and apply it to a beam splitter assembled from rectangular photonic crystals(PCs).The constructed beam splitter structure is compact and possesses frequency separation functions.In addition,we construct a box-shaped triangular PC structures with zipper-like boundaries and discover phenomena of TCSs in the corners,comparing its corner states with those formed by other boundaries.Based on this,we explore the regularities of the electric field patterns of TESs and TCSs,explain the connection between the characteristic frequencies and locality of TCSs,which helps better control photons and ensures low power consumption of the system.

关键词： valley photonic crystal topological edge states topological corner states higher-order topological insulators topological phase transition

基于两种梁理论对变幅锥形杆弯曲振动的特性分析及参数设计

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振动与冲击 2024年第2期43卷 114-122页

作者：常婷婷沈峰鲍四元苏州科技大学工程力学系江苏苏州215011

为了研究圆锥形杆自由振动的特性,分别基于欧拉-贝努力梁理论和铁木辛柯梁理论,建立变截面杆自由振动的分析模型。采用一种含三角函数的级数形式来表示欧拉-贝努利梁理论下杆的位移函数,以满足端部位移的条件;利用能量泛函极小化得到系... 详细信息

为了研究圆锥形杆自由振动的特性,分别基于欧拉-贝努力梁理论和铁木辛柯梁理论,建立变截面杆自由振动的分析模型。采用一种含三角函数的级数形式来表示欧拉-贝努利梁理论下杆的位移函数,以满足端部位移的条件;利用能量泛函极小化得到系数满足的线性方程组,进而获得不同边界条件下圆锥形杆在欧拉-贝努利梁理论下的若干阶固有频率;类似地,假设位移的级数形式并利用能量函数,建立锥形杆基于铁木辛柯梁理论的求解方法,可得各阶固有频率和模态;给出等截面杆在两种理论下固有频率的转化公式,并推广应用到圆锥形杆的固有频率近似转化。算例分析锥形杆截面参数对结构固有频率的影响,并基于目标设计频率和若干限制条件对锥形杆的尺寸进行设计。数值结果表明,在应用欧拉-贝努利梁理论和铁木辛柯梁理论时,所提方法都能够稳定收敛且计算效率高,具有较高的精确度。该研究工作为超声工程中变幅杆的动力学特性提供了计算依据。

关键词：铁木辛柯梁理论变幅杆新型改进傅里叶级数自由振动固有频率

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探意“府”穴与“门”穴

中华中医药杂志 2024年第6期39卷 2785-2787页

作者：沈峰李丹妮湖北中医药大学武汉430061

十四正经中以“府”命名的腧穴共有6个,分别是“中府”“天府”“府舍”“少府”“俞府”和“风府”。进一步系统梳理发现相应“府”穴邻近均有以“门”命名的腧穴。府为藏物之处,门以开关为用,二者可分不可离,强烈提示“府”穴与“门... 详细信息

十四正经中以“府”命名的腧穴共有6个,分别是“中府”“天府”“府舍”“少府”“俞府”和“风府”。进一步系统梳理发现相应“府”穴邻近均有以“门”命名的腧穴。府为藏物之处,门以开关为用,二者可分不可离,强烈提示“府”穴与“门”穴之间隐含着更为深刻的内在必然联系。文章试从腧穴名称角度出发,综合运用汉字等中华优秀传统文化知识,结合中医经典文献及现代研究,探析“府”穴与“门”穴背后的深意,希冀为培养针灸临床思维、领悟中医原创理论提供一个新的视角。

关键词：腧穴名称中府天府少府风府俞府府舍

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循环肿瘤细胞在肝细胞癌诊疗中的应用及展望

海军军医大学学报 2024年第4期45卷 495-499页

作者：吴雅丽张小峰沈锋广东药科大学第一临床医学院广州510006 海军军医大学(第二军医大学)第三附属医院肝外四科上海200438

肝细胞癌(HCC)是一种高度恶性肿瘤,是癌症相关死亡的第三大原因。血清甲胎蛋白和影像学检查是HCC早期诊治和疗效动态监测最常用的手段。然而这些手段的准确性有限,不能明确反映肿瘤的潜在生物学特性。因此,开发能够更准确、全面地反映HC... 详细信息

肝细胞癌(HCC)是一种高度恶性肿瘤,是癌症相关死亡的第三大原因。血清甲胎蛋白和影像学检查是HCC早期诊治和疗效动态监测最常用的手段。然而这些手段的准确性有限,不能明确反映肿瘤的潜在生物学特性。因此,开发能够更准确、全面地反映HCC生物学特性的新型肿瘤标志物具有潜在的临床应用价值。循环肿瘤细胞(CTC)是来源于原发肿瘤或转移灶并存在于血液循环中的癌细胞,其提供了关于肿瘤进展和转移的重要信息,是早期诊断和复发、转移、预后评估的良好候选指标,甚至是HCC潜在的治疗靶点。本文讨论了CTC在HCC患者临床全疗程管理中的应用及其局限性和未来研究方向。

关键词：肝细胞癌循环肿瘤细胞检测方法临床应用

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一种抗畸变的增强型八节点等参元

中山大学学报（自然科学版）（中英文） 2024年第3期63卷 163-171页

作者：乔海青鲍四元沈峰苏州科技大学土木工程学院江苏苏州215011

为了提高平面问题的求解精度,基于勒让德正交函数族引入泡状函数来增强映射关系的思想,构造Q8_Legendre单元。针对单元的位移场中含有泡状函数导致单元刚度矩阵规模变大的问题,在得到单元刚度矩阵后附加自由度凝聚,以减小整体刚度矩阵... 详细信息

为了提高平面问题的求解精度,基于勒让德正交函数族引入泡状函数来增强映射关系的思想,构造Q8_Legendre单元。针对单元的位移场中含有泡状函数导致单元刚度矩阵规模变大的问题,在得到单元刚度矩阵后附加自由度凝聚,以减小整体刚度矩阵规模、节省计算机内存空间。算例表明,随着泡状函数项数的不断增加,Q8_Legendre单元能够通过分片试验,使得单元的位移精度得到改善,而应力精度保持相当。当出现畸变网格时,Q8_Legendre单元表现出抗畸变的性能,且不会出现闭锁现象。

关键词：平面问题泡状函数位移修正模型高斯积分抗畸变

Role of post-hepatectomy portal hypertension in predicting the outcome of hepatocellular carcinoma after curative resection

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Portal Hypertension & Cirrhosis 2024年第2期3卷 75-85页

作者： Jian Lin Liangrui Chen Xiaodong Shi fengwei Li Qian Xu Hongzhi Liu Jingfeng Liu Kui Wang feng shen Department of Hepatic Surgery Eastern Hepatobiliary Surgery HospitalSecond Military Medical UniversityShanghaiChina Department of Public Health Fujian University of Traditional Chinese MedicineCollege of Integrative MedicineFuzhouFujianChina Department of Hepatopancreatobiliary Surgery Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhouFujianChina Department of Hepatopancreatobiliary Surgery Cancer Hospital of Fujian Medical UniversityFuzhouFujianChina

Aims:Portal venous pressure frequently increases after a major hepatectomy.We aimed to assess the outcomes of patients with hepatocellular carcinoma(HCC)with different post-hepatectomy portal pressure statuses and the predictive factors correlated with prognosis and post-hepatectomy portal hypertension(PHPH).Methods:Data from consecutive patients who underwent curative-intent hepatectomy for HCC at the Eastern Hepatobiliary Surgery Hospital and Mengchao Hepatobiliary Hospital of Fujian Medical University between January 2008 and December 2016 were retrospectively analyzed.Patients were followed up until March 1,2022.PHPH was defined as new-onset portal hypertension(PH)in patients without preoperative PH within 1 month of hepatectomy.Patients were classified into two groups according to the presence or absence of PHPH:non-PH and PHPH.The clinicopathological characteristics were compared between the two groups.Univariate and multivariate analyses were used to identify independent risk factors for early and late recurrence of HCC,overall survival(OS),and PHPH.Results:Disease-free survival rates were significantly higher in the non-PH group(n=1068)than those in the PHPH group(n=423)(62.0%,39.0%,and 31.0%vs.46.2%,24.5%,and 19.3%at 1,3,and 5 years,respectively;all p40 U/L,and major hepatectomy were identified as independent risk factors for PHPH.Conclusions:PHPH was associated with early recurrence of HCC and poor OS but not with late recurrence.Therefore,PHPH may be an attractive target for therapeutic interventions and follow-up surveillance to improve

关键词： hepatocellular carcinoma hepatectomy portal hypertension prognosis predictive factors

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微流控粒子分选中圆形微凹槽容纳特性研究

力学学报 2024年第5期56卷 1317-1327页

作者：申峰张杰艾明珠张越东刘赵淼北京工业大学数学统计学与力学学院北京100124 西安交通大学航天航空学院机械结构强度与振动国家重点实验室西安710049

微流控技术由于具备操控微通道中微小体积流体的能力,已成为操控粒子和细胞的新平台.基于粒子惯性迁移和微凹槽涡胞捕获的粒子分选方法,是一种重要的微流控粒子操控技术.目前,微凹槽容纳的粒子数量不高,制约了该方法的效率.为了提高微... 详细信息

微流控技术由于具备操控微通道中微小体积流体的能力,已成为操控粒子和细胞的新平台.基于粒子惯性迁移和微凹槽涡胞捕获的粒子分选方法,是一种重要的微流控粒子操控技术.目前,微凹槽容纳的粒子数量不高,制约了该方法的效率.为了提高微凹槽粒子容量,对圆形微凹槽进行结构设计,并利用高速显微成像技术和数值模拟,研究了不同圆形微凹槽的粒子容纳能力.研究发现,相同入口雷诺数(Re=37~555)下,带底腔的圆形微凹槽相较于普通圆形微凹槽容纳的粒子数量提升了45%,这是因为增加底腔后使得涡流线向下延展,形成更深的“U形”结构,可以容纳更多的粒子;当Re=482时,带底腔的直径500μm的圆凹槽比直径600μm的圆凹槽的粒子容量提高了93.9%,原因是前者凹槽内粒子运动轨道与流线更加吻合,粒子轨道面积与凹槽面积占比达到了97%;随着Re增加,从侧通道收集到的粒子富集浓度整体呈现先缓慢增大后减小的趋势,收集到的20μm粒子的最大富集浓度为初始悬浮液的126.7倍;不同微凹槽内粒子群的轨道运动受到涡流场特性、粒子物性及粒子间相互作用和壁面限制作用等因素的共同影响.研究结果对微凹槽结构设计和提高粒子分选性能有重要指导意义.

关键词：微流控技术粒子分选微凹槽粒子捕获涡胞