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Grey Prediction Based Software Stage-Effort Estimation

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Wuhan University Journal of Natural Sciences 2007年第5期12卷 927-931页

作者： WANG Yong SONG Qinbao shen junyi Department of Computer Science Xi＇an Jiaotong University Xi＇an 710049 Shaanxi China

The software stage-effort estimation can be used to dynamically adjust software project schedule, further to help make the project finished on budget. This paper presents a grey model Verhulst based method for stage-effort estimation during software development process, a bias correction technology was used to improve the estimation accuracy. The proposed method was evaluated with a large-scale industrial software engineering database. The results are very encouraging and indicate the method has considerable potential.

关键词： project management software engineering sorftware effort estimation grey model

Synthesis and characterization of soluble intrinsic black polyimide with excellent comprehensive properties

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Science China(Technological Sciences) 2023年第12期66卷 3604-3614页

作者： TAN JingHua shen junyi HUANG Jie ZHAO ChunBo LI HuiPeng LIU XueYuan XIE FengYun LIU YiWu National and Local Joint Engineering Research Center for Advanced Packaging Materials and Technology Key Laboratory of Advanced Packaging Materials and Technology of Hunan ProvinceSchool of Packaging and Materials EngineeringHunan University of TechnologyZhuzhou 412007China

Black polyimides(BPIs)have attracted increasing attention owing to their growing demand in ***,commonly used black polyimides doped with black fillers suffer from poor mechanical and electrical *** address these issues,a new diamine(2,5-bis(4′-amino-[1,1′-biphenyl]-4-yl)-3,4-bis(4-fluorophenyl)cyclopenta-2,4-dien-1-one,TPCPFPDA)bearing a tetraphenylcyclopentadienone(TPCP)moiety bonded with benzene and fluorine units was *** diamine was reacted with 4,4′-(hexafluoroisopropylidene)diphthalic anhydride(6FDA)to yield a soluble intrinsic black polyimide(TPCPFPPI).Bonding fluorine(auxochrome group)and benzene units to TPCP can increase the conjugation ofπ-electrons systems and facilitate the movement of electron throughout the bigπbond,*** to the structural features,the synthesized TPCPFPPI exhibited complete visible-light absorption with high blackness and *** cutoff wavelength(λ_(cut))and CIE(Commission Internationale de I′Eclairage)parameter L^(*)were 684 nm and 1.33,***,TPCPFPPI displayed exceptional electrical,mechanical,and thermal properties as well as excellent solubility.A detailed theoretical calculation was conducted to gain better insight into the electronic properties of the *** showed that the blackness of TPCPFPPI was chiefly attributed to the electron transition from highest occupied molecular orbital(HOMO)to lowest unoccupied molecular orbital(LUMO)in the diamines,where the charges primarily migrated from the aryl groups in the 2-and 5-positions to the cyclopentadienone *** as-obtained intrinsic BPI(TPCPFPPI),exhibiting both high solubility and outstanding overall properties,has important applications in photo-electronics.

关键词： intrinsic black polyimide complete visible light absorption excellent solubility tetraphenylcyclopentadienone chromophore theoretical calculation

Improvement of hemodynamics in mesenteric microcirculation in septic shock rats by anisodamine and anisodine

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Mechanobiology in Medicine 2023年第1期1卷 51-60页

作者： Jian Zhong Zhi Ouyang junyi shen Ye Zeng Institute of Biomedical Engineering West China School of Basic Medical Sciences and Forensic MedicineSichuan UniversityChengdu610041China

Anisodamine and anisodine have been used in treatment of septic shock,but the underlying mechanism are still *** the present study,the effects of anisodamine hydrobromide(Ani HBr)and anisodine hydrobromide(AT3)on the mesenteric hemodynamics in septic shock rats were *** rat model of septic shock was established by intravenous tail vein injection of 5 mg/kg lipopolysaccharide(LPS),and then treated with Ani HBr,AT3,racemic anisodine(Race Ani)or atropine(ATP).The mesenteric microcirculation was observed using the intravital ***,the flow pattern of the microcirculation,leukocytes dynamics and the plasma levels of cytokines tumor necrosis factor(TNF)-αand interleukin-6(IL-6)were *** with the control rats,reduced mean arterial pressure,increased heart rate,and slow microcirculatory blood flow was found in septic shock *** main abnormal flow patterns were intermittent and reciprocating *** HBr,AT3,Race Ani and ATP elevated the mean arterial pressure and reduced heart rate in septic shock *** HBr and AT3 not only restored the velocity of microcirculatory blood flow and improved the microcirculatory flow patterns,but also suppressed the LPS-induced leukocyte-endothelium interaction and releases of TNF-αand ***,Ani HBr and AT3 improves hemodynamics in both macro-and microcirculation,which provide a novel experimental basis for exploring the mechanobiological mechanisms in septic shock.

关键词： Sepsis Microcirculation Hemodynamics Flow pattern Leukocyte Anisodamine Anisodine

A novel method for extracting and optimizing the complex permittivity of paper-based composites based on an artificial neural network model

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Science China(Technological Sciences) 2024年第10期67卷 3190-3204页

作者： XIA ChenBin shen junyi LIAO ShaoWei WANG Yi HUANG Zhengsheng XUE Quan TANG Min LONG Jin HU Jian School of Light Industry and Engineering South China University of TechnologyGuangzhou 510641China School of Electronic and Information Engineering South China University of TechnologyGuangzhou 510641China

Measuring the complex permittivity of ultrathin,flexible materials with a high loss tangent poses a substantial challenge with precision using conventional methods,and verifying the accuracy of test results remains *** this study,we introduce a methodology based on a back-propagation artificial neural network(ANN)to extract the complex permittivity of paper-based composites(PBCs).PBCs are ultrathin and flexible materials exhibiting considerable complex permittivity and dielectric loss *** the absence of mature measurement methods for PBCs and a lack of sufficient data for ANN training,a mapping relationship is initially established between the complex permittivity of honeycomb-structured microwave-absorbing materials(HMAMs,composed of PBCs)and that of PBCs using simulated *** the ANN model,the complex permittivity of PBCs can be extracted from that of HMAMs obtained using standard ***,two published methods are cited to illustrate the accuracy and advancement of the results obtained using the proposed ***,specific error analysis is conducted,attributing discrepancies to the conductivity of PBCs,the homogenization of HMAMs,and differences between the simulation model and actual ***,the proposed method is applied to optimize the cell length parameters of HMAMs for enhanced absorption *** conclusion discusses further improvements and areas for extended research.

关键词： paper-based composite honeycomb complex permittivity artificial neural networks inverse modeling

A novel nine gene signature integrates stemness characteristics associated with prognosis in hepatocellular carcinoma

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BIOCELL 2021年第6期45卷 1425-1448页

作者： XINGHONG YAO CHENGQUAN LU junyi shen WENLI JIANG YAN QIU YE ZENG LIANG LI Institute of Biomedical Engineering West China School of Basic Medical Sciences&Forensic MedicineSichuan UniversityChengdu610041China Department of Radiation Oncology Sichuan Cancer Hospital&InstituteSchool of Medicine of University of Electronic Science and Technology of ChinaChengdu610041China Jinzhou City Center for Disease Control and Prevention Jinzhou121000China

Cancer stem cells(CSCs)are heterogeneous with self-renewal and differentiation *** mRNA expression-based stemness index(mRNAsi)described the similarity between tumor cells and CSCs,which is positively associated with the poor prognosis of cancer ***,the key prognostic genes related to mRNAsi in hepatocellular carcinoma(HCC)remains unclear.A 9-gene signature related to mRNAsi and HCC prognosis including PSMG3,SNRPD1,DTYMK,PIGU,NME1,TXNL4A,IPO4,PES1,and REXO4 was *** expression of this signature indicates poor prognosis of *** was an independent prognostic factor of HCC,which was significantly associated with progression of *** them,DTYMK and NME1 enriched in pyrimidine metabolism,SNRPD1 and TXNL4A enriched in spliceosome and PIGU enriched in glycosyl phosphatidylinositol(GPI)-anchor biosynthesis *** levels of IPO4,NME1,PES1,PIGU and SNRPD1 were closely associated with metastasis of HCC,and low levels of IPO4,PIGU and REOX4 were significantly associated with sorafenib resistance of *** expression of the 9-gene signature was negatively correlated with the stromal cell infiltration,and positively correlated with specific immune subtypes-related to angiogenesis,M1/M2 macrophage polarization,and M2 *** 9-gene signature was negatively correlated with the stroma,and SNRPD1 and TXNL4 were positively correlated with immune ***1 was negatively correlated with tumor ***,a 9-gene signature related to mRNAsi and poor prognosis in HCC were identified,which can be used as biomarkers for the diagnosis of HCC and functional mechanism exploration of CSCs in *** genes such as IPO4 and PIGU might drive the transition of tumor cells into CSCs which possibly controls the balance between metastasis and drug resistance in *** challenge on balance between metastasis and drug resistance for tumor therapy was firstly reported by the present study.

关键词： Stemness index Hepatocellular carcinoma Prognosis Microenvironment

An Incremental Algorithm of Text Clustering Based on Semantic Sequences

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Wuhan University Journal of Natural Sciences 2006年第5期11卷 1340-1344页

作者： FENG Zhonghui shen junyi BAO Junpeng Institute of Computer Software Xi＇an Jiaotong UniversityXi＇an 710049 Shaannxi China

This paper proposed an incremental textclustering algorithm based on semantic sequence. Using similarity relation of semantic sequences and calculating the cover of similarity semantic sequences set, the candidate cluster with minimum entropy overlap value was selected as a result cluster every time in this algorithm. The comparison of experimental results shows that the precision of the algorithm is higher than other algorithms under same conditions and this is obvious especially on long documents set.

关键词： text clustering semantic sequence entropy

Application Server Aging Model and Multi-Level Rejuvenation Strategy Using Semi-Markov Process

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Wuhan University Journal of Natural Sciences 2006年第5期11卷 1209-1215页

作者： ZHAO Tianhai QI Yong shen junyi HOU Di ZHENG Xiaomei LIU Liang School of Electronics and Information Engineering Xi＇an Jiaotong University Xi＇an 710049 Shaanxi China IBM China Research Laboratory Beijing 100094China

Aiming at the characteristic of the dependency between the application components and the application server platform, a rejuvenation strategy with two different levels of rejuvenation granularities is put forward in this paper including the application component reiuvenation and the application server system rejuvenation. The availability and maintenance cost functions are obtained by means of establishing the application server aging model and the boundary condition of the optimal rejuvenation time is analyzed. Theory analysis indicates that the two-level rejuvenation strategy is superior to the traditional single level one. Finally, evaluation experiments are carried out and numerical result shows that compared with the traditional rejuvenation policy, the rejuvenation strategy proposed in this paper can further increase availability of the application server and reduce maintenance cost.

关键词： application server software rejuvenation reliability software maintenance

Design and Implement of Personalized Distance Education System Based on Web Usage Mining

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通讯和计算机（中英文版） 2006年第7期3卷 31-35,48页

作者： Jiangchun Song junyi shen School of Electronics and Information Engineering Xi＇an Jiaotong University Xi ＇an 710049. China

Anisodine hydrobromide alleviates oxidative stress caused by hypoxia/reoxygenation in human cerebral microvascular endothelial cells predominantly via inhibition of muscarinic acetylcholine receptor 4

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BIOCELL 2023年第10期47卷 2255-2263页

作者： WENLI JIANG junyi shen XIAOQIANG DU YAN QIU JIAN ZHONG ZHI OUYANG BINGMEI M.FU YE ZENG Institute of Biomedical Engineering West China School of Basic Medical Sciences&Forensic MedicineSichuan UniversityChengdu610041China Department of Biomedical Engineering The City College of the City University of New YorkNew York10031USA

Background:Anisodine hydrobromide(AT3),an anti-cholinergic agent,could be delivered to the brain across the blood-brain barrier and has been used clinically for the treatment of cerebral ischemia/reperfusion *** dysfunction can be caused by hypoxia/reoxygenation(H/R)via oxidative stress and metabolic *** present study investigated whether AT3 regulates the production of nitric oxide(NO)and reactive oxygen species(ROS),and the HIF-1αpathway via regulation of muscarinic acetylcholine receptors(mAChRs)in brain microvascular endothelial cells after H/R ***:Under H/R conditions,hCMEC/D3 cerebral microvascular endothelial cells were treated with *** inhibitors of M2-and M4-mAChRs were used to explore the mechanism by which AT3 influences oxidative stress in endothelial ***,mAChRs expression was detected by western blotting and NO production was detected by Greiss *** intracellular ROS level was measured using DCFH-DA *** expression of hypoxia-inducible transcription factor 1α(HIF-1α)was also ***:While H/R induced the expression of M2-and M4-mAChRs,AT3 suppressed the H/R-upregulated M2-and M4-mAChRs.H/R also induced the production of NO,ROS,and ***3 and M4-mAChR inhibitors inhibited the H/R-induced production of NO and ROS and ***-1αwas induced by H/R,but was suppressed by ***:Thus,the in vitro evidence shows that AT3 protects against H/R injury in cerebral microvascular endothelial cells via inhibition of HIF-1α,NO and ROS,predominantly through the downregulation of *** findings offer novel understandings regarding AT3-mediated attenuation of endothelial cell apoptosis and cerebral ischemia/reperfusion injury.

关键词： Hypoxia/reoxygenation Endothelial cell Anisodine hydrobromide Muscarinic acetylcholine receptors Hypoxia-inducible factor-1α