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Changes in regeneration and leaf traits of Rhododendron campanulatum along a treeline ecotone in central Nepal

Journal of Mountain Science 2020年第3期17卷 602-613页

作者： sharma prasad krishna TIWARI Achyut SHRESTHA Babu Bharat Central Department of Botany Tribhuvan UniversityKathmandu44613Nepal Budhanilkantha School Kathmandu44622Nepal

Changes in population structure and plant functional traits across environmental gradient in the near natural treeline is a critical determinant of environmental changes in treelines. In this study we analyzed population characteristics and leaf traits of Rhododendron campanulatum across treeline ecotone in a trans-Himalayan region of Mustang district in central Nepal. Along 4 vertical transects, a total of 72 quadrats(5 m × 5 m)-34 above Betula utilis treeline and 38 below treeline-were sampled to analyze the population structure, regeneration,specific leaf area(SLA) and leaf-stem relationship of R. campanulatum. Our results showed that the regeneration of R. campanulatum was fairly good in both habitats, as evident from density-diameter *** species showed type Ⅲ survivorship curve in both habitats with the highest mortality during early stage of life. However, the seedling density and mortality was higher below treeline than above treeline. Canopy cover and basal cover were found to be the major factors affecting regeneration, as indicated by higher number of juveniles in relatively open areas above treeline. The total leaf area increased(p <0.001) with stem cross-section area in both habitats. However, the SLA was higher below treeline(55 cm^2/g) than above(47 cm^2/g)(p < 0.001);it also increased with the canopy cover of trees(R^2 =0.59, p <0.001) below the treeline. In conclusion,high density of juvenile, low mortality of seedlings,and low SLA above treeline indicated that the species has successfully adapted in climatically stressful alpine habitat with potential to expand upward.

关键词： Rhododendron Climate change Life table Mortality Specific leaf area Mustang district

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Comparative efficacy of hyperbaric bupivacaine vs hyperbaric ropivacaine in spinal anesthesia for cesarean section:A metaanalysis

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World Journal of Methodology 2025年第2期15卷 154-165页

作者： Rishi Anand Deb Sanjay Nag Roushan Patel Prashant sharma Vamsi krishna Uppalapati Umesh Kumar Singh Department of Anaesthesiology Tata Main HospitalJamshedpur 831001JhārkhandIndia

BACKGROUND Intrathecal bupivacaine is the traditional anesthetic drug used in spinal anesthesia for caesarean sections(CSs),but ropivacaine has emerged as a potential *** meta-analysis compares the efficacy and safety of intrathecal hyper-baric bupivacaine vs hyperbaric ropivacaine for cesarean *** To systematically evaluate and compare the efficacy and safety of intrathecal hyperbaric bupivacaine and hyperbaric ropivacaine for spinal anesthesia in *** A thorough search of electronic databases was carried out to find pertinent randomized controlled trials(RCTs)comparing intrathecal hyperbaric ropi-vacaine and hyperbaric bupivacaine during ***,Cochrane database,Google Scholar,and Scopus were searched,and papers from January 2000 to January 2024 were deemed eligible and filtered using predetermined inclusion and exclusion *** were assessed for methodological quality,and data were extracted for time to adequate anesthesia(sensory and motor blockade),duration of sensory and motor block,hemodynamic changes and side effect *** standardized mean difference with 95%CI was used for continuous *** variables were assessed using the Mantel-Haenszel test and the random effect model to compute the odds *** Total 8 RCTs were selected from a pool of 119 search results for *** meta-analysis evaluated pooled effect sizes and assessed heterogeneity among the *** primary objective was to compare key outcomes to identify any significant variances in efficacy and safety profiles between two local *** analysis revealed that the difference in the onset of sensory blockade between the two local anesthetics was statistically insignificant(P=0.1586).However,the onset of motor blockade appeared to be faster with bupivacaine(P=0.03589).Additionally,the regression of sensory and motor blockade occurred earlier in the ropivacaine ***,the duration of the first analgesic

关键词： Ropivacaine Bupivacaine Anesthesia Spinal Cesarean section Meta-analysis

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Recovery of the injured neural system through gene delivery to surviving neurons in Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2855-2861页

作者： Chanchal sharma Sehwan Kim Hyemi Eo Sang Ryong Kim School of Life Science Kyungpook National UniversityDaeguKorea BK21 FOUR KNU Creative BioResearch Group Kyungpook National University DaeguKorea Brain Science and Engineering Institute Kyungpook National UniversityDaeguKorea

A critical unaddressed problem in Parkinson’s disease is the lack of therapy that slows or hampers *** medications effectively manage symptoms,they offer no long-term benefit because they fail to address the underlying neuronal *** highlights that the elusive goals of halting progression and restoring damaged neurons limit the long-term impact of current *** clinical trials using gene therapy have demonstrated the safety of various vector delivery systems,dosages,and transgenes expressed in the central nervous system,signifying tangible and substantial progress in applying gene therapy as a promising Parkinson’s disease ***,at diagnosis,many dopamine neurons remain in the substantia nigra,offering a potential window for recovery and *** propose that modulating these surviving dopamine neurons and axons in the substantia nigra and striatum using gene therapy offers a potentially more impactful therapeutic approach for future ***,innovative gene therapies that focus on preserving the remaining elements may have significant potential for enhancing long-term outcomes and the quality of life for patients with Parkinson’s *** this review,we provide a perspective on how gene therapy can protect vulnerable elements in the substantia nigra and striatum,offering a novel approach to addressing Parkinson’s disease at its core.

关键词： adeno-associated virus gene therapy neuroprotection neurorestoration neurotrophic factor nigrostriatal dopamine pathway pro-survival protein

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Recognition and quality mapping of traditional herbal drugs:way forward towards artificial intelligence

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Traditional Medicine Research 2025年第1期10卷 12-26页

作者： Sanyam sharma Subh Naman Ashish Baldi Faculty of Pharmacy Pacific Academy of Higher Education and Research UniversityUdaipur 313024India Pharma Innovation Lab Department of Pharmaceutical Sciences and TechnologyMaharaja Ranjit Singh Punjab Technical UniversityBathinda 151001India Faculty of Pharmaceutical Sciences The ICFAI UniversityBaddi 174103India.

The use of traditional herbal drugs derived from natural sources is on the rise due to their minimal side effects and numerous health ***,a major limitation is the lack of standardized knowledge for identifying and mapping the quality of these herbal *** article aims to provide practical insights into the application of artificial intelligence for quality-based commercialization of raw herbal *** focuses on feature extraction methods,image processing techniques,and the preparation of herbal images for compatibility with machine learning *** article discusses commonly used image processing tools such as normalization,slicing,cropping,and augmentation to prepare images for artificial intelligence-based *** also provides an overview of global herbal image databases and the models employed for herbal plant/drug *** will gain a comprehensive understanding of the potential application of various machine learning models,including artificial neural networks and convolutional neural *** article delves into suitable validation parameters like true positive rates,accuracy,precision,and more for the development of artificial intelligence-based identification and authentication techniques for herbal *** article offers valuable insights and a conclusive platform for the further exploration of artificial intelligence in the field of herbal drugs,paving the way for smarter identification and authentication methods.

关键词： artificial intelligence Ayurveda machine learning models herbal drugs image pre-processing medicinal plants

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New pseudo-dynamic analysis of two-layered cohesive-friction soil slope and its numerical validation

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Frontiers of Structural and Civil Engineering 2020年第6期14卷 1492-1508页

作者： Suman HAZARI Sima GHOSH Richi prasad sharma Department of Civil Engineering National Institute of TechnologyAgarala 799046India

Natural slopes consist of non-homlogeneous soil profiles with distinct characteristics from slopes made of homogeneous *** this study,the limit equilibrium modified pseudo-dynamic method is used to analyze the stability of two-layered c-φsoil slopes in which the failure surface is assumed to be a logarithmic *** zero-stress boundary condition at the ground surface under the seismic loading condition is *** formulations derived from an analytical method are proposed for the predicting the seismic response in two-layered soil.A detailed parametric study was performed in which various parameters(seismic accelerations,damping,cohesion,and angle of internal friction)were *** results of the present method were compared with those in the available *** present analytical analysis was also verified against the finite element analysis results.

关键词： layered soil limit equilibrium method seismic analysis damping PLAXIS

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Ethanol steam reforming study over ZSM-5 supported cobalt versus nickel catalyst for renewable hydrogen generation

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Chinese Journal of Chemical Engineering 2019年第3期27卷 677-684页

作者： Ashutosh Kumar Ram prasad Yogesh Chandra sharma Department of Chemistry Indian Institute of Technology (Banaras Hindu University) Varanasi Department of Chemical Engineering & Technology Indian Institute of Technology (Banaras Hindu University) Varanasi

The renewable hydrogen generation through ethanol steam reforming is one of the anticipated areas for sustainable hydrogen generation. To elucidate the role of Ni and Co with ZSM-5 support, catalysts were prepared by wet impregnation method and ethanol steam reforming(ESR) was performed. The catalysts were characterized by HR-XRD, ATR–FTIR, HR-SEM, TEM with SAED, EDAX, surface area analyzer and TPR. It had shown complete ethanol conversion at 773 K, but the selectivity in hydrogen generation was found higher for 10% Ni/ZSM-5 catalyst as compared to 10% Co/ZSM-5. The 10% Ni/ZSM-5 catalyst has about 72% hydrogen selectivity at temperature 873 K. It indicates that Ni is a more sustainable catalyst as compared to Co with ZSM-5 support for ESR. The C_2H_4 was found major undesirable products up to 823 K temperature. Nevertheless, the 10% Ni/ZSM-5 catalyst had shown its stability for high temperature(873 K) ESR performance.

关键词： Ethanol steam reforming Zeolite Hydrogen Renewable energy Catalyst

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Rock-like behavior of biocemented sand treated under non-sterile environment and various treatment conditions

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Journal of Rock Mechanics and Geotechnical Engineering 2021年第3期13卷 705-716页

作者： Meghna sharma Neelima Satyam krishna RReddy Discipline of Civil Engineering Indian Institute of Technology IndoreIndore453552India Department of Civil Materialsand Environmental EngineeringUniversity of Illinois at ChicagoChicagoILUSA

Microbially induced calcite precipitation(MICP)is a recently developed technique for microbiological ground improvement that has been applied for mitigating various geotechnical ***,the major challenges,such as calcite precipitation uniformity,presence of different bacteria,cementation solution optimization for cost reduction,and implementation under non-sterile and uncontrolled field environment are still not fully explored and require detailed investigation before field *** study aims to address these challenges of MICP to improve the geotechnical properties of sandy *** series of experiments were conducted using poorly graded Narmada River(India)sand,which were subjected to various biotreatment schemes and tested for unconfined compressive strength(UCS),split tensile strength(STS),ultrasonic pulse velocity(UPV),hydraulic conductivity(after 6 d,12 d,and 18 d of treatment),and calcite *** microstructure of sand was examined through a scanning electron microscope(SEM).Initially,the sand was individually augmented with two non-pathogenic bacterial strains,***(S.)pasteurii and Bacillus(B.)*** stopped-flow injection method was adopted to provide cementation solutions at three different durations(treatment cycle)of 12 h,24 h,and 48 h and three different pore volumes(PVs)of 1,0.75,and *** pore volume here refers to the porosity which is expressed as a ratio,i.e.a porosity of 50%was used as *** results showed rock-like behaviors of biocemented sand with the UCS,STS,and UPV enhancement up to 2333 kPa,437 kPa,and 2670 m/s,*** hydraulic conductivity reduction of 96.6%was achieved by 12%of calcite formation after 18 d of treatment using Sporosarcina pasteurii,12-h treatment cycle,and one pore volume of cementation media in each ***,a 24-h treatment cycle and 0.5-pore volume cementation solution were found to be the optimal treatment which was effective and economical to achiev

关键词： Bacteria Microbially induced calcite precipitation (MICP) Soil stabilization Microstructure Calcite content

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The effects of climate and land use change on the potential distribution and nesting habitat of the Lesser Adjutant in Nepal

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Avian Research 2023年第3期14卷 326-335页

作者： Hem Bahadur Katuwal Hari prasad sharma Prashant Rokka krishna prasad Bhusal Bishnu prasad Bhattarai Sabina Koirala Sandeep Chhetri Luitel Shailendra Yadav Ganesh Sah Hem Sagar Baral Laxman prasad Poudyal Lin Wang Rui-Chang Quan Center for Integrative Conservation Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMenglaYunnan666303China Southeast Asia Biodiversity Research Institute Chinese Academy of SciencesYezinNay Pyi Taw05282Myanmar Yunnan International Joint Laboratory of Southeast Asia Biodiversity Conservation MenglaYunnan666303China Nepal Zoological Society Kathmandu44600Nepal Central Department of Zoology Institute of Science and TechnologyTribhuvan UniversityKathmandu44600Nepal Faculty of Forestry Agriculture and Forestry UniversityHetaudaMakwanpur44107Nepal IUCN SSC Bird Red List Authority Rue Mauverney1196GlandSwitzerland Mithila Wildlife Trust JanakpurdhamDhanusa45600Nepal Zoological Society of London-Nepal Office Kathmandu44600Nepal Institute of Land Water and SocietySchool of Environmental SciencesCharles Sturt UniversityAlbury-WodongaAustralia Shivapuri-Nagarjun National Park Department of National Parks and Wildlife ConservationKathmanduNepal

Climate change and land use change pose a threat to the world’s biodiversity and have significant impacts on the geographic distribution and composition of many bird species,but little is known about how they affect threatened large-sized waterbird species that rely on agricultural *** address this gap,we investigated how climate and land use changes influence the distribution and nesting habitats of the globally vulnerable Lesser Adjutant(Leptoptilos javanicus) in *** 2012 and 2023,we collected distribution data from 24 districts and nesting site information from 18 *** a nation-wide breeding survey conducted in 2020,we documented a total of 581 fledglings from 346 nests in 109 *** ensemble model predicted a current potential distribution of 15%(21,637 km2) and a potential nesting habitat of 13%(19,651 km2) for the species in *** highest predicted current suitable distribution and nesting habitat was in Madhesh Province,while none was predicted in Karnali *** majority of this predicted distributional and nesting habitat falls on agricultural landscapes(>70%).Our model showed a likely range expansion of up to 15%(21,573 km2) for the distribution and up to 12%(17,482 km2) for the nesting habitat under SSP5-8.5 scenarios for the *** range expansion is expected to occur mainly within the current distribution and breeding range(Tarai and some regions of Siwalk),particularly in Lumbini and Sudurpashchim provinces,and extend to the northern portions(Siwalik and Mid-hill regions) in other ***,the current Protected Areas and Important Bird and Biodiversity Areas are inadequate for providing optimal habitats for the *** the model suggests range expansion,the use of such novel habitats is primarily contingent on the availability and protection of large-sized trees(particularly Bombax ceiba,observed in 65% of colonies) in agricultural regions where nesting ***,our research sugges

关键词： Agricultural landscapes Bombax ceiba Ensemble modeling Farmland bird IBA Nest site

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Wind pollination in Pinus roxburghii

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Progress in Natural Science:Materials International 2007年第1期17卷 32-38页

作者： Vinod prasad KHANDURI Chandra Mohan sharma Department of Forestry Mizoram University Aizawl(Mizoram)India Department of Forestry HNB Garhwal University Srinagar Garhwal-246 174(Uttaranchal)India

Stigmatic pollen load and pollen concentration in the air were studied in the natural population of Pinus roxburghii at Ashtavakra (900 m asl), in the Pauri forest division of Garhwal Himalaya, India. The results reflect diurnal pollen occurrence in P. roxburghii , with the strong significant correlations between pollen concentrations in the air and wind speed, air temperature and relative air humidity. A significant correlation was also observed between microsporangium dehiscence and pollen occurrence in the air. The maximum concentration of pollen grains in the air and higher rates of pollen deposition onto the megasporophylls were between 12 pm and 16 pm of the day, which conforms the best time for pollination in a day in P. roxburghii. The receptivity of Ovulate strobili varied from 3 to 5 days, however, the bagged strobili remained receptive up to 6 days.

关键词： ovulate strobili pollen cones pollination receptivity wind speed P. roxburghii.

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Improved Energy Management Strategy for Prosumer Buildings with Renewable Energy Sources and Battery Energy Storage Systems

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Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 381-392页

作者： Pavitra sharma krishna Kumar Saini Hitesh Datt Mathur Puneet Mishra Department of Electrical&Electronics Engineering Birla Institute of Technology&SciencePilaniIndia IEEE

The concept of utilizing microgrids(MGs)to convert buildings into prosumers is gaining massive popularity because of its economic and environmental *** pro-sumer buildings consist of renewable energy sources and usually install battery energy storage systems(BESSs)to deal with the uncertain nature of renewable energy ***,because of the high capital investment of BESS and the limitation of available energy,there is a need for an effective energy management strategy for prosumer buildings that maximizes the profit of building owner and increases the operating life span of *** this regard,this paper proposes an improved energy management strategy(IEMS)for the prosumer building to minimize the operating cost of MG and degradation factor of ***,to estimate the practical operating life span of BESS,this paper utilizes a non-linear battery degradation *** addition,a flexible load shifting(FLS)scheme is also developed and integrated into the proposed strategy to further improve its *** proposed strategy is tested for the real-time annual data of a grid-tied solar photovoltaic(PV)and BESS-powered AC-DC hybrid MG installed at a commercial ***,the scenario reduction technique is used to handle the uncertainty associated with generation and load *** validate the performance of the proposed strategy,the results of IEMS are compared with the well-established energy management *** simulation results verify that the proposed strategy substantially increases the profit of the building owner and operating life span of ***,FLS enhances the performance of IEMS by further improving the financial profit of MG owner and the life span of BESS,thus making the operation of prosumer building more economical and efficient.

关键词： Prosumer building battery energy storage system(BESS) battery degradation factor demand response energy management microgrid solar photovoltaic(PV)system

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