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Western medication plus Traditional Chinese Medicine preparations in patients with chronic heart failure:a prospective,single-blind,randomized,controlled,and multicenter clinical trial

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Journal of Traditional Chinese Medicine 2017年第6期37卷 756-766页

作者： Wang Xianliang Hou Yazhu Mao Jingyuan Zhao Yingqiang Niu Tianfu Yuan Ruyu Wang yonggang Cui Jin-rong Shi Le Jia Xiuli Fan Ruihong Lin Qian Zhang Yan Li Zhijun shang Hongcai Wang Baohe Wang Hongwu Wang Henghe Cui Xiaolei Soh Shanbin Ruan Jishou Zhang Boli Cardiovascular Department the First Teaching Hospital of Tianjin University of Traditional Chinese Medi-cineTianjin 300193China Cardiovascular Department the SecondTeaching Hospital of Tianjin University of Traditional Chi-nese MedicineTianjin 30015OChina Cardiovascular Department Shanxi TraditionalChinese Medicine InstituteTaiyuan 030012China Cardiovascular Department the Second Teach-ing Hospital of Tianjin Medical UniversityTianjin 300211China Cardiovascular Department the SecondTeaching Hospital of Shanxi University of Traditional Chinese MedicineXianyang 712000China Cardiovascular Department the Integrated Hospitals of TCM and Western Medicine of Shanxi Universityof Traditional Chinese MedicineTaiyuan 030001China Cardiovascular Department Tianjin Beichen Tradi-tional Chinese Medicine HospitalTianjin 300400China Cardiovascular Department Tianjin Nankai Tradi-tional Chinese Medicine HospitalTianjin 300102China Cardiovascular Department Tianjin Tradition-al Chinese Medicine HospitalTianjin 300020China Cardiovascular Department the Eastern Hospitalof Beijing University of Traditional Chinese MedicineBeijing 100078China Evidence-based medicinecenter Tianjin University of Traditional Chinese MedicineTianjin 300193China Statistic Department Tianjin University ofTraditional Chinese MedicineTianjin 300193China Institute of Traditional Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjin 300193China Graduate school Tianjin Universi-ty of Traditional Chinese MedicineTianjin 300193China Ruan JishouDepartment of MathematicsNankai Universi-tyTianjin 300071China

OBJECTIVE: To assess the efficacy and safety in patients with chronic heart failure(CHF) of Western medication plus Traditional Chinese Medicine(TCM) ***: This prospective, single-blind, randomized, controlled, and multicenter clinical trial began on September 17, 2008, and was completed on June 25, 2011. A total of 340 inpatients, aged 40-79 years, with exacerbating CHF from 10 hospitals were enrolled and randomly allocated within 24 h of admission. The trial included three intervention periods. During hospitalization, the control group received western medication for CHF and the treatment group received Danhong injection with Shenfu injection or Shenmai injection. After discharge,all patients were treated with Qiliqiangxin capsules and Buyiqiangxin tablets or a placebo for 6 months. After the 6-month intervention, both groups received only continuous western medication. The primary endpoint was all-cause *** efficacy assessments were as follows: B-type natriuretic peptide(BNP), Lee's HF score, the 6-minute walking test(6 MWT), left ventricular ejection fraction(LVEF), and the Minnesota Living with Heart Failure Questionnaire(MLHFQ). The safety assessments were as follows: blood and urine routine examination, hepatic and renal function, electrolytes in blood and adverse ***: Compared with the control group, the treatment group showed a 30.99% reduction in all-cause mortality and an improved survival *** treatment group showed greater improvement in 6 MWT(P = 0.02) than the control group on discharge, after 12-month follow-up, there was a time-group interaction for MLHFQ(P = 0.03). Incidence rate of adverse events and other relevant safety indexes were not statistically significant between the two ***: Western medication plus TCM treatment can increase 6-minute walking distance(improve exercise tolerance) and quality of life with heart failure patients.

关键词： Heart failure Medicine, Chinese tradi-tional Walk test Randomized controlled trail

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平面运动约束下的相对位姿估计最小配置解

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中国科学：技术科学 2024年第11期54卷 2122-2130页

作者：关棒磊赵季尚洋于起峰国防科技大学空天科学学院长沙410073 图像测量与视觉导航湖南省重点实验室长沙410073 华中科技大学人工智能与自动化学院武汉430074

基于视觉的相对位姿估计是自动驾驶车辆等移动机器人进行自主定位与环境感知的核心关键技术.为提高相对位姿估计算法的精度、效率和鲁棒性,寻求相对位姿估计的最小配置解一直是重点关注的研究热点.传统的相对位姿估计算法通常仅使用图... 详细信息

基于视觉的相对位姿估计是自动驾驶车辆等移动机器人进行自主定位与环境感知的核心关键技术.为提高相对位姿估计算法的精度、效率和鲁棒性,寻求相对位姿估计的最小配置解一直是重点关注的研究热点.传统的相对位姿估计算法通常仅使用图像匹配点对中的图像坐标信息,忽略特征描述子提供的特征旋转角和尺度等额外信息.针对移动机器人应用中单目相机平面运动这一常见情景,本文利用图像特征描述子提供的信息中的约束方程,提出了一种新的平面运动估计最小配置解.根据地面场景上图像特征满足的单应约束,利用单个旋转不变特征中的图像坐标和旋转角信息,闭式求解单目相机平面运动的相对位姿.由于该方法所需要的特征数量最少,因此可以高效地与RANSAC方法或直方图投票方法相结合,用于两视图之间的初始运动估计和误匹配点对剔除.仿真和公开数据集实验表明,本文能够明显提高单目相机平面运动估计的精度和鲁棒性,可运用于自动驾驶车辆等移动机器人在地面、道路等典型场景上的自主定位与视觉感知.

关键词：相对位姿估计单目相机最小配置解旋转不变特征

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A Novel Fluorescent Probe for Lead Ions

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Chinese Chemical Letters 2003年第10期14卷 1024-1026页

作者： Ming SUN, Di Hua shang guan, Hui Min MA, Li Hua NIE, Xiao Hua LIShao Xiang XIONGLaboratory of Chemical Biology, Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080 Laboratory of Chemical Biology Center for Molecular Sciencese Institute of Chemistry Chinese Academy of Sciencese Beijing 100080

A new fluorescent probe for lead ions,p-nitrophenyl 3H-phenoxazin-3-one-7-yl phosphoric acid (NPPA), has been synthesized by linking resorufin (serving as a fluorophore and electron acceptor) to p-nitrophenol (serving as a fluorescence quencher and electron donor) through phosphodiester bonds. When NPPA was irradiated with light, intramolecular fluorescence self-quenching took place due to the PET (photoinduced electron transfer) from the donor to the acceptor. However, upon addition of PbII, the phosphate ester bonds in the probe were cleaved and the fluorophore was released, accompanying the retrievement of fluorescence.

关键词： Fluorescent probe lead phosphodiester hydrolysis.

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Synthesis of ZSM-5 Zeolite with Small Crystallite and its Application in Aromatiration of Propane

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Chinese Chemical Letters 1999年第6期10卷 519-520页

作者： Ming LIU Nai Jia guan Shou He XIANG Jian Xiang ZHANG shang Yuan LIU Shu Quan LIU (Department of Chemistry. Nankai University. Tianjin 300071 Catalyst Plant of Nankai University.Tianjin 300071) Department of Chemistry Nankai University Tianjin 300071 China Catalyst Plant of Nankai University Tianjin 300071 China

By optimizing the orystallization condition, a procedure for the synthesis of small crystallite zeolite ZSM-5 was developed. Compared with the larger crystallite ZSM-5. the smaller one exhibits higher catalytic perfor... 详细信息

关键词： ZSM-5 zeolite small crystallite size aromatization propane

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Effect of combined therapy of Yinchenhao Chengqi decoction and endoscopic sphincterotomy for endotoxemia in acute cholangitis

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World Journal of Gastroenterology 1998年第5期4卷 80-82页

作者： shang Dong 1, guan Feng Lin 1, JIN Pei Yu 2, CHEN Hai Long 1 and CUI Jian Hua 2

AIM To evaluate the therapeutic mechanism of Yinchenhao Chengqi (YCHCQ) decoction (containing mainly Herba Artemisia capillaris) combined with endoscopic sphincterotomy (EST) for endotoxemia (ETM) in acute *** Twenty-one cases of acute cholangitis with ETM were divided randomly into two groups: group A, 10 patients treated with YCHCQ decoction combined with EST, group B, 11 patients treated with EST. The incidence rate of ETM, plasmic ET, serum superoxide dismutase (SOD) activity, malonyldialdehyde (MDA), complement C3 and C-reactive protein (CRP) were studied *** The ET level of group A (35.92ng/L±8.30ng/L) was significantly reduced after 7 days of treatment (P＜0.05) in contrast to that of group B (47.8ng/L±11.62ng/L), so did the level of MDA and CRP. But the SOD activity and C3 level in group A increased significantly (P＜0.05).CONCLUSION YCHCQ decoction combined with EST had a beneficial effect for ETM in acute *** (ETM) is one of the most important physiopathologic causes of acute cholangitis and it is the trigger of cytokines and inflammatory factors. In recent studies it has been found that Yinchenhao Chengqi (YCHCQ) decoction has a beneficial effect on ETM in acute cholangitis. With the development of endoscopic surgery, endoscopic sphincterotomy (EST) has become an effective replacement for some operations in the treatment of acute cholangitis[1]. The effect of YCHCQ decoction combined with EST on ET, oxygen free radical and complement C3 was observed in order to find out its therapeutic mechanism.

关键词： cholangitis endotoxemia sphincterotomy endoscopy Yin Chen Hao Cheng Qi decoction

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Subseasonal Zonal Oscillation of Western Pacific Subtropical High during Early Summer

Subseasonal Zonal Oscillation of Western Pacific Subtropical...

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第35届中国气象学会年会

作者： REN Xuejuan guan Weina shang Wei HU Haibo School of Atmospheric Sciences Nanjing University

This study examines the features and dynamical processes of subseasonal zonal oscillation of the western Pacific subtropical high(WPSH)during early summer,by performing a multivariate empirical orthogonal function(MV-EOF)analysis on daily winds and a diagnosis on potential vorticity(PV)at 500 h Pa for the period *** first MV-EOF mode is characterized by an anticyclonic anomaly occupying southeastern China-subtropical western North Pacific *** has a period of 10–25 days and represents zonal shift of the *** the WPSH stretches more westward,the South Asian high(SAH)extends more *** above-normal precipitation is observed over the Yangtze-Huaihe River(YHR)basin.A suppressed convection with an anomalous descending motion is located over the subtropical western North Pacific(Fig.1).The relative zonal movement of the SAH and the WPSH contributes to establish an anomalously local vertical circulation of ascending motion with upper level divergence over the YHR basin,and descending motion with upper level convergence over the subtropical western *** local vertical circulation provides a dynamic condition for persistent rainfall over the YHR *** enhanced southwest flow over the WPSH's western edge transports more moisture to eastern China,providing a necessary vapor condition for the persistent rainfall over the YHR basin.A potential vorticity diagnosis reveals that anomalous diabatic heating is a main source of PV *** anomalous cooling over the subtropical western Pacific produces a locally negative PV center at 500 h *** anomalous heating over the YHR basin generates a locally positive PV *** above south-north dipolar structure of PV anomaly along with the climatological southerly flow leads to northward advection of negative *** two processes are conducive to the WPSH's westward *** vertical advection process is unfavorable to the westward extension but contributes to the eastward retreat of

关键词： western Pacific subtropical high subseasonal time-scale diabatic heating potential vorticity

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Advances in Chemical Constituents and Quality Control of Turmeric

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World Journal of Traditional Chinese Medicine 2019年第2期5卷 116-121页

作者： Zhan-Peng shang Lu-Lu Xu Ying-Ying Lu Meng guan De-Yun Li Zhi-Yong Le Zong-Li Bai Xue Qiao Min Ye State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking University China Meheco Herbs C0. Ltd. Kangmei Pharmaceutical Co. Ltd.BeijingChina

Turmeric, derived from the rhizomes of Curcuma longa L.(Zingiberaceae),is one of the most popular herbal *** main bioactive constituents include curcuminoids,sesquiterpenes, and *** exhibits antitumor,anti-inflammatory, antioxidant,antibacterial,and antiviral *** the rapid development of analytical technologies,remarkable progress has been made in studies of *** review article summarizes research advances in chemical analysis and quality control of turmeric from 2009 to 2018.

关键词： Bioactive constituents quality control review turmeric

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SYNTHESIS AND CRYSTAL STRUCTURE OF CARBOXYETHYL-TRICHL0ROGERM ANIUM

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结构化学 1989年第3期 177-179页

作者： shang-guan Guo-Qiang Zhang Shu-Gong Jin Zhong-Sheng Ni Jia-Zan Changchun Institute of Applied Chemistry, Academia Sinica, Changchun

C3H5Cl3GeO2, Mr = 252. 01, monoclinic, space group P21/n with a=6. 828(1),b= 10. 069(2) ,e= 12. 196(2) A ,B=101. 94(1) ,Z= 4,V= 820. 3A3, Dc=2. 041gcm-3, (MoKa) = 0.71073A,u=48. 96cm-1,F(000) = 647. 88. The Ge atom is coordinated by three chloro atoms and one carbon atom from carboxyethyl, forming an irregular tetrahedral geometry with average Ge-Cl distance of 2. 130(2) and the Ge-C distance of 1.946(5)A. Each two molecules are bound together by hydrogen bonds between the carboxyl groups to form a dimer.

关键词： CI SYNTHESIS AND CRYSTAL STRUCTURE OF CARBOXYETHYL-TRICHL0ROGERM ANIUM Cl

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根域限制和氮素水平对连翘幼苗生长的影响

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生态学报 2007年第4期27卷 1323-1332页

作者：安慧上官周平西北农林科技大学黄土高原土壤侵蚀与旱地农业国家重点实验室

在植物生长箱通过溶液培养试验，从叶片光合气体交换参数、叶绿素含量及其荧光参数等方面来探讨不同氮素浓度条件下根域体积对连翘幼苗光合生理特性及生长的影响，并采用^15N示踪技术对不同氮素浓度条件下根域体积对连翘幼苗体内氮素转... 详细信息

在植物生长箱通过溶液培养试验，从叶片光合气体交换参数、叶绿素含量及其荧光参数等方面来探讨不同氮素浓度条件下根域体积对连翘幼苗光合生理特性及生长的影响，并采用^15N示踪技术对不同氮素浓度条件下根域体积对连翘幼苗体内氮素转运进行了研究。结果表明：低氮（LN）处理幼苗的地上部和根系干物质重较高氮（HN）处理的高，根域限制对地上部和根系干物质重的影响不同，LN处理幼苗地上部和根系干物质重在低根域体积（10cm×10cm×15cm，LR）处理均较高根域体积（20cm×10cm×15cm，HR）处理的低，HN处理的幼苗响应情况有所不同。LN处理幼苗的叶片净光合速率（Pn）和叶绿素含量较HN处理的高；LN处理幼苗Pn和气孔导度（Gs）在LR处理较HR处理的高，而HN处理幼苗的Pn和Gs随根域体积变化规律与LN处理相反，LN和HN处理叶绿素含量随根域体积变化规律与Pn相反。LN处理幼苗的PSⅡ最大光化学量子效率（Fv／Fm）和PSⅡ电子传递量子效率（ФPSⅡ）均较HN处理的高，不同供氮处理下LR处理幼苗的Fv／Fm均较HR处理的高；而ФPSⅡ的变化规律相反。不同供氮处理时，LR处理幼苗的光化学猝灭系数（qP）均较HR处理的低，而非光化学猝灭系数（qNP）的变化规律相反，LN处理幼苗的qNP较HN处理的高（P〈0．05）。不同供氮处理时，LR处理幼苗根系和地上部氮含量均较HR处理的低，LN处理幼苗根系和地上部氮含量较HN处理的低，幼苗根系和地上部氮含量随氮素浓度变化差异显著（P〈0．05）。LN处理幼苗根系吸收^15N在根系和叶片的分配率均较HN处理的低，而根系吸收^15N在枝和茎的分配率呈相反变化规律。根系吸收氮在叶片和枝的分配率分别为7％～10％和7％～12％，叶片和枝生长需要的氮素主要由其内源N库提供。

关键词：根域限制连翘气体交换参数氮素分配氮素水平

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电镀综合废水对DF膜的污染

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环境工程学报 2015年第4期9卷 1803-1808页

作者：薛勇刚官嵩戴晓虎同济大学苏州研究院苏州215100 污染控制与资源化研究国家重点实验室同济大学上海200092

江苏某电镀厂的电镀综合废水在采用DF膜进行预处理时,膜易受到污染。针对这一问题,采用DF膜生产厂家提供的小试装置,研究探索了膜污染的原因及其具体特征。实验结果表明,在处理电镀综合废水时,DF膜的污染速率较快,而酸洗对DF膜的恢复性... 详细信息

江苏某电镀厂的电镀综合废水在采用DF膜进行预处理时,膜易受到污染。针对这一问题,采用DF膜生产厂家提供的小试装置,研究探索了膜污染的原因及其具体特征。实验结果表明,在处理电镀综合废水时,DF膜的污染速率较快,而酸洗对DF膜的恢复性较好,研究还证实电镀综合废水中的无氰沉锌水洗液是造成DF膜污染的主要原因。

关键词：膜污染电镀废水 DF膜

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