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Journal of Iron and Steel Research International 2024年第8期31卷 2053-2067页

作者： Kang Zhou Wen-xiao yu.Bao-kai Ren Gang Wang School of Mechatronical Engineering Beijing Institute of TechnologyBeijing 100081China

Online estimation of the double nugget diameters was performed by means of a back propagation neural *** double nugget diameters were obtained using actual welding experiment and numerical simulation,according to different characteristics of aluminum nugget and steel *** input of the neural network was some key characteristic parameters extracted from dynamic power signal,which were peak point,knee point and their variation rate over time,as well as heat energy delivered into the welding *** architecture of the neural network was confirmed by confirming the number of neurons in hidden layer through a series of *** key parameters of the neural network were obtained by means of training 81 arrays of data ***,the neural network was used to test the remaining 20 arrays of verifying data set,and the results showed that both of the mean errors for the two nugget diameters were below 3%.In addition,corresponding analyses showed that the accuracy of two nugget diameters was higher than that of tensile-shear strength.

关键词： Resistance spot welding Aluminum Steel Double nugget Dynamic power signal.Neural network

Core shift limitation in investment casting process of hollow turbine blade

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Chinese Journal of Aeronautics 2024年第8期37卷 513-526页

作者： Kang CUI Lin JING Ruisong JIANG Longnv yu.xiao GAO Automation and Software Engineering Shanxi UniversityTaiyuan 030006China Key Laboratory of High Performance Manufacturing for Aero Engine Ministry of Industry and Information TechnologySchool of Mechanical EngineeringNorthwestern Polytechnical UniversityXi’an 710072China School of Mechanical Engineering Sichuan UniversityChengdu 610065China

The deviation in wall thickness caused by core shift during the investment casting process significantly impacts the strength and service life of hollow turbine *** address this issue,a core shift limitation method is developed in this ***,a shift model is established based on computational fluid dynamics and motion simulation to predict the movement of the ceramic core in investment casting ***,utilizing this model,an optimization method for fixturing layout inside the refractory ceramic shell is devised for the ceramic *** casting experiment demonstrates that by utilizing the optimized fixture layout,not only can core shift during the investment casting pouring process be effectively controlled,but also the maximum wall thickness error of the blade can be reduced by 42.02%.In addition,the core shift prediction is also validated,with a prediction error of less than 26.9%.

关键词： Hollow turbine blade Wall thickness Ceramic core Shift prediction Fixturing layout optimization

Highly Thermoconductive,Strong Graphene‑Based Composite Films by Eliminating Nanosheets Wrinkles

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Nano-Micro Letters 2024年第1期16卷 328-340页

作者： Guang xiao Hao Li Zhizhou yu.Haoting Niu Yagang Yao College of Engineering and Applied Sciences Jiangsu Key Laboratory of Artificial Functional Materialsand Collaborative Innovation Center of Advanced MicrostructuresNational Laboratory of Solid State MicrostructuresNanjing UniversityNanjing 210093People’s Republic of China Institute of Laser Manufacturing Henan Academy of SciencesZhengzhou 450052People’s Republic of China Center for Quantum Transport and Thermal Energy Science School of Physics and TechnologyNanjing Normal UniversityNanjing 210023People’s Republic of China

Graphene-based thermally conductive composites have been proposed as effective thermal management materials for cooling high-power electronic ***,when flexible graphene nanosheets are assembled into macroscopic thermally conductive composites,capillary forces induce shrinkage of graphene nanosheets to form wrinkles during solution-based spontaneous drying,which greatly reduces the thermal conductivity of the ***,graphene nanosheets/aramid nanofiber(GNS/ANF)composite films with high thermal conductivity were prepared by in-plane stretching of GNS/ANF composite hydrogel networks with hydrogen bonds andπ-π*** in-plane mechanical stretching eliminates graphene nanosheets wrinkles by suppressing inward shrinkage due to capillary forces during drying and achieves a high in-plane orientation of graphene nanosheets,thereby creating a fast in-plane heat transfer *** composite films(GNS/ANF-60 wt%)with eliminated graphene nanosheets wrinkles showed a significant increase in thermal conductivity(146 W m^(−1)K^(−1))and tensile strength(207 MPa).The combination of these excellent properties enables the GNS/ANF composite films to be effectively used for cooling flexible LED chips and smartphones,showing promising applications in the thermal management of high-power electronic devices.

关键词： Graphene Aramid nanofiber Wrinkles elimination In-plane stretching Thermal conductivity

Research Progress on the Pathogenesis and Treatment of Neoatherosclerosis

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Current Medical Science 2024年第4期44卷 680-685页

作者： Yi-shan GUO Ning YANG Zhen WANG yu.miao WEI Department of Cardiology Hubei Key Laboratory of Biological Targeted TherapyHubei Engineering Research Center for Immunological Diagnosis and Therapy of Cardiovascular DiseasesUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China Department of Cardiology Binzhou Medical University HospitalBinzhou256600China Department of Gynecology Binzhou Medical University HospitalBinzhou256600China

Neoatherosclerosis(NA)within stents has become an important clinical problem after coronary artery stent ***-stent restenosis and in-stent thrombosis are the two major complications following coronary stent placement and seriously affect patient *** the common pathological basis of these two complications,NA plaques,unlike native atherosclerotic plaques,often grow around residual oxidized lipids and stent *** main components are foam cells formed by vascular smooth muscle cells(VSMCs)engulfing oxidized lipids at lipid residue *** research mainly focuses on optical coherence tomography(OCT)and intravascular ultrasound(IVUS),but the specific pathogenesis of NA is still unclear.A thorough understanding of the pathogenesis and pathological features of NA provides a theoretical basis for clinical *** article reviews the previous research of our research group and the current situation of domestic and foreign research.

关键词： neoatherosclerosis vascular smooth muscle cells

Prediction and driving factors of forest fire occurrence in Jilin Province,China

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Journal of Forestry Research 2024年第1期35卷 58-71页

作者： Bo Gao Yanlong shan Xiangyu.Liu Sainan Yin Bo yu.Chenxi Cui Lili Cao Wildland Fire Prevention and Fighting Innovation Center of Beihua University Forestry College of Beihua University3999 Binjiang East RoadJilin City 132013People’s Republic of China

Forest fires are natural disasters that can occur suddenly and can be very damaging,burning thousands of square *** is better than suppression and prediction models of forest fire occurrence have developed from the logistic regression model,the geographical weighted logistic regression model,the Lasso regression model,the random forest model,and the support vector machine model based on historical forest fire data from 2000 to 2019 in Jilin *** models,along with a distribution map are presented in this paper to provide a theoretical basis for forest fire management in this *** studies show that the prediction accuracies of the two machine learning models are higher than those of the three generalized linear regression *** accuracies of the random forest model,the support vector machine model,geographical weighted logistic regression model,the Lasso regression model,and logistic model were 88.7%,87.7%,86.0%,85.0%and 84.6%,*** is the main factor affecting forest fires,while the impacts of topography factors,human and social-economic factors on fire occurrence were similar.

关键词： Forest fire Occurrence prediction Forest fire driving factors Generalized linear regression models Machine learning models

Engineering CuMn Prussian blue analog-shelled nanobox for efficient electrochemical reduction of nitrate to ammonia

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Tungsten 2024年第4期6卷 833-844页

作者： Zi-Yi Yang yu.Dong Li Dan Liu Mao-Sen Song Yang Gao Qing-Ping Wu En-shan Han Yan-Zhen He xiao-Hui Yang School of Chemical Engineering and Technology Hebei University of Technology Key Laboratory of Bio-Based Material Science and Technology Northeast Forestry University Institute of Electrochemical Energy Storage Helmholtz-Zentrum Berlin für Materialien und Energie Chongqing Institute of Green and Intelligent Technology Chinese Academy of Sciences

Electrocatalytic nitrate reduction reaction（ENRR） for ammonia synthesis is a promising strategy to relieve nitration contamination,as well as an alternative to the Haber-Bosch *** blue analogs（PBAs） are expected to be an electrocatalytic material with superior performance owing to their abundant active sites and open channel ***,most reported PBA materials possess low nitrate conversion and ammonia yield rates,which has led to a hindrance in their research of ***,CuMn-PBA-shelled nanoboxes（CuMn-PBA SNBs） synthesized through tannic acid etching and cation exchange approaches are demonstrated for efficient ammonia *** optimal CuMn-PBA SNBs electrode achieves a high nitrate conversion of 91.33% and ammonia selectivity of 98.87% in a 0.2 mol·L-1Na2SO4solution with100×10-6NO3--N at-1.4 V ***,the CuMn-PBA SNB s electrode exhibits exceptional stability throughout a 30 h electrocatalytic *** outstanding electrochemical performance is attributed to the unique hollow nanobox structure with abundant active sites and high-throughput transport pathways for ions' aspects.

关键词： Acid etching Ammonia synthesis Cation exchange Electrocatalytic nitrate reduction Nanobox Prussian blue analogs

Synthesis and microwave absorption performance of heat-treated RF/SiO_(2)aerogels

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Defence Technology（防务技术） 2024年第4期34卷 177-186页

作者： Xinli Ye Hao yu.Kai Zheng shan Li xiaomin Ma Bangxiao Mao Junxiong Zhang School of Civil Aviation Northwestern Polytechnical UniversityXi’an 710072PR China Research&Development Institute of Northwestern Polytechnical University in Shenzhen Shenzhen 518057PR China Yangtze River Delta Research Institute of Northwestern Polytechnical University Suzhou 215400PR China National Equipment New Material&Technology(Jiangsu)Co. LtdSuzhou 215400PR China Beijing Xinfeng Aerospace Equipment Co. LtdBeijing 100854PR China School of Textile and Clothing Nantong UniversityNantong 226019PR China

The well-designed composite with satisfactory electromagnetic microwave absorption at high temperatures remains a serious ***,we fabricated a resorcinol-formaldehyde/silica dioxide composite aerogel(RF/SiO_(2))with a three-dimensional network structure using sol-gel,atmospheric pressure drying technique as well as heat-treated processes to achieve enhanced microwave absorption capabilities in the low frequency *** pristine RF/SiO_(2)aerogel presented a typical micropores structure with a surface area,porous volume,and density of 146.82 m^(2)/g,62.40%,and 0.28 cm^(3)/g,***,the RF/SiO_(2)aerogel showed an effective absorption bandwidth of 3.56 GHz and a minimum reflection loss value of-46.10 d B at 2.25 mm after being heat-treated at 1500°C,while the maximum effective absorption bandwidth was 3.60 GHz at 2.30 *** intricate three-dimensional networks possessed remarkable impedance matching,multiple attenuation mechanisms,interfacial polarization,and dielectric loss,which were attributed to the exceptional ability to absorb electromagnetic *** offered a fresh approach to creating adaptable and effective microwave absorption materials in military defense.

关键词： RF/SiO_(2) Aerogel Heat-treated Microwave absorption

Ginsenoside Rd Induces Differentiation of Myeloid Leukemia Cells via Regulating ERK/GSK-3βSignaling Pathway

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Chinese Journal of Integrative Medicine 2024年第7期30卷 588-599页

作者： JIANG yu.xia ZHAO Yan-na yu.xiao-ling YIN Li-ming Department of Hematology Tongde Hospital of Zhejiang ProvinceHangzhou310012China Institute of Hematology Research the First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine)Hangzhou310006China

Objective To investigate the role of ginsenoside Rd(GRd)in acute myeloid leukemia(AML)cell *** AML cells were treated with GRd(25,50,100 and 200µg/mL),retinoic acid(RA,0.1g/L)and PD98059(20 mg/mL)for 72 h,cell survival was detected by methylthiazolyldiphenyl-tetrazolium bromide and colony formation assays,and cell cycle was detected by flow *** morphology and differentiation were observed by Wright-Giemsa staining,peroxidase chemical staining and cellular immunochemistry assay,*** protein expression levels of GATA binding protein 1(GATA-1),purine rich Box-1(PU.1),phosphorylated-extracellular signal-related kinase(p-ERK),ERK,phosphorylated-glycogen synthase kinase-3β(p-GSK3β),GSK3βand signal transducer and activator of transcription 1(STAT1)were detected by Western ***-six mice were randomly divided into 3 groups using a random number table:model control group(non-treated),GRd group[treated with 200 mg/(kg·d)GRd]and homoharringtonine(HTT)group[treated with 1 mg/(kg·d)HTT].A tumor-bearing nude mouse model was established,and tumor weight and volume were *** of subcutaneous tumor tissue were observed after hematoxylin and eosin ***1 and GATA-1 expressions were detected by immunohistochemical *** The cell survival was inhibited by GRd in a dose-dependent manner and GRd caused G0/G1 cell arrest(p<0.05).GRd treatment induced leukemia cell differentiation,showing increased expressions of peroxidase and specific proteins concerning erythrogenic or granulocytic differentiation(p<0.05).GRd treatment elicited upregulation of p-ERK,p-GSK-3βand STAT1 expressions in cells,and reversed the effects of PD98059 on inhibiting the expressions of peroxidase,GATA-1 and PU.1(P<0.05).After GRd treatment,tumor weight and volume of mice were decreased,and tumor cells underwent massive apoptosis and necrosis(P<0.05).WT1 level was decreased,and GATA-1 level was significantly increased in subcutaneous tumor ti

关键词： ginsenoside Rd myeloid leukemia survival differentiation extracellular signal-related kinase signaling pathway

Recanalization of anastomotic occlusion following rectal cancer surgery using a rendezvous endoscopic technique with transillumination:A case report

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World Journal of Gastroenterology 2024年第37期30卷 4149-4155页

作者： Jun Chi Guang-yu.Luo Hong-Bo shan Jun-Zhong Lin xiao-Jun Wu Jian-Jun Li Department of Endoscopy Sun Yat-Sen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina State Key Laboratory of Oncology in South China Guangzhou 510060Guangdong ProvinceChina Guangdong Provincial Clinical Research Center for Cancer Guangzhou 510060Guangdong ProvinceChina Department of Colorectal Surgery Sun Yat-Sen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina

BACKGROUND Colorectal anastomotic occlusion is a serious complication of colorectal cancer *** several treatment strategies have been proposed,the mana-gement of anastomotic occlusion remains *** this report,we present a case of anastomotic occlusion recanalization performed using a novel technique involving two endoscopes,one for radial incision and the other serving as a guide *** novel technique offers significant advantages in terms of operational feasibility,reduced invasiveness,rapid recovery,and shortened hospital *** SUMMARY A 37-year-old man underwent low anterior resection and prophylactic double-lumen ileostomy for rectal cancer in June,*** months later,complete anastomotic occlusion was observed on ***,we developed a novel atresia recanalization *** endoscopes were placed,one through the colonic anastomosis and the other through the anus.A radial incision was successfully made from the colonic side,guided by the light of the endoscope from the anal *** recanal-ization was performed within 20 *** weeks after recanalization,colonoscopy revealed that the diameter of the colorectal anastomosis was approximately 16 mm and the patient therefore underwent stoma reversal in *** the follow-up period of approximately one year,the patient remained well and no stenosis or obstruction symptoms were *** Endoscopic atresia recanalization of colorectal anastomotic occlusion assisted by an opposing light source is safe and effective.

关键词： Endoscopy Atresia recanalization Anastomotic occlusion Light source Case report

GATA binding protein 2 mediated ankyrin repeat domain containing 26 high expression in myeloid-derived cell lines

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World Journal of Stem Cells 2024年第5期16卷 538-550页

作者： Yang-Zhou Jiang Lan-yu. Hu Mao-shan Chen xiao-Jie Wang Cheng-Ning Tan Pei-Pei Xue Teng yu.xiao-Yan He Li-Xin Xiang Yan-Ni xiao xiao-Liang Li Qian Ran Zhong-Jun Li Li Chen Laboratory of Radiation Biology Department of Blood TransfusionLaboratory Medicine CenterThe Second Affiliated HospitalThird Military Medical UniversityChongqing 400037China Hematopoietic Acute Radiation Syndrome Medical and Pharmaceutical Basic Research Innovation Center Ministry of Education of the People’s Republic of ChinaChongqing 400037China

BACKGROUND Thrombocytopenia 2,an autosomal dominant inherited disease characterized by moderate thrombocytopenia,predisposition to myeloid malignancies and normal platelet size and function,can be caused by 5’-untranslated region(UTR)point mutations in ankyrin repeat domain containing 26(ANKRD26).Runt related transcription factor 1(RUNX1)and friend leukemia integration 1(FLI1)have been identified as negative regulators of ***,the positive regulators of ANKRD26 are still *** To prove the positive regulatory effect of GATA binding protein 2(GATA2)on ANKRD26 *** Human induced pluripotent stem cells derived from bone marrow(hiPSC-BM)INTRODUCTION Ankyrin repeat domain containing protein 26(ANKRD26)acts as a regulator of adipogenesis and is involved in the regulation of feeding behavior[1-3].The ANKRD26 gene is located on chromosome 10 and shares regions of homology with the primate-specific gene family *** to the Human Protein Atlas database,the ANKRD26 protein is localized to the Golgi apparatus and vesicles,and its expression can be detected in nearly all human tissues[4].Moreover,UniProt annotation revealed that ANKRD26 is localized in the centrosome and contains coiled-coil domains formed by spectrin helices and ankyrin repeats[5,6].The most common disease related to ANKRD26 is thrombocytopenia 2(THC2),which is a rare autosomal dominant inherited disease characterized by lifelong mild-to-moderate thrombocytopenia and mild bleeding[7-9].Caused by the variants in the 5’-untranslated region(UTR)of ANKRD26,THC2 is defined by a decrease in the number of platelets in circulating blood and results in increased bleeding and decreased clotting ability[8,10].Due to the point mutations that occur in the 5’-UTR of ANKRD26,its negative transcription factors(TFs),Runt related transcription factor 1(RUNX1)and friend leukemia integration 1(FLI1),lose their repression effect[11].The persistent expression of ANKRD26 increases the activi

关键词： Ankyrin repeat domain containing 26 GATA binding protein 2 Thrombocytopenia 2 Transcriptional regulation Myeloid-derived cell lines