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Updated roles of the gut microbiota in exploring shrimp etiology, polymicrobial pathogens, and disease incidence

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Zoological Research 2024年第4期45卷 910-923页

作者： Jin-Bo Xiong Hao-Nan sha Jiong Chen State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products School of Marine SciencesNingbo UniversityNingboZhejiang 315211China Key Laboratory of Aquacultural Biotechnology Ministry of EducationSchool of Marine SciencesNingbo UniversityNingboZhejiang 315211China Laboratory of Biochemistry and Molecular Biology School of Marine SciencesNingbo UniversityNingboZhejiang 315211China

Litopenaeus vannamei is the most extensively cultured shrimp species globally,recognized for its scale,production,and economic ***,its aquaculture is plagued by frequent disease outbreaks,resulting in rapid and massive *** research often lags behind the emergence of new diseases,leaving the causal agents of some shrimp diseases unidentified and leading to nomenclature based on symptomatic presentations,especially in cases involving co-and polymicrobial *** data on shrimp disease statuses remain *** this review,we summarize current knowledge on shrimp diseases and their effects on the gut ***,we also propose a workflow integrating primary colonizers,“driver”taxa in gut networks from healthy to diseased states,disease-discriminatory taxa,and virulence genes to identify potential polymicrobial *** examine both abiotic and biotic factors(e.g.,external and internal sources and specific-disease effects)that influence shrimp gut microbiota,with an emphasis on the“holobiome”concept and common features of gut microbiota response to diverse *** excluding the effects of confounding factors,we provide a diagnosis model for quantitatively predicting shrimp disease incidence using disease common-discriminatory taxa,irrespective of the causal *** to the conservation of functional genes used in designing specific primers,we propose a practical strategy applying qPCR-assayed abundances of disease common-discriminatory functional *** review updates the roles of the gut microbiota in exploring shrimp etiology,polymicrobial pathogens,and disease incidence,offering a refined perspective for advancing shrimp aquaculture health management.

关键词： Shrimp disease Gut microbiota Polymicrobial pathogens Diagnosis model Disease common-discriminatory taxa Disease prediction

Distributed Graph Database Load Balancing Method Based on Deep Reinforcement Learning

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Computers, Materials & Continua 2024年第6期79卷 5105-5124页

作者： Shuming sha Naiwang Guo Wang Luo Yong Zhang Nanjing NARI Information&Communication Technology Co. Ltd.Nanjing210032China State Grid Electric Power Research Institute Nanjing211106China State Grid shanghai Municipal Eleciric Power Company Shanghai200122China

This paper focuses on the scheduling problem of workflow tasks that exhibit *** indepen-dent batch tasks,workflows typically consist of multiple subtasks with intrinsic correlations and *** necessitates the distribution of various computational tasks to appropriate computing node resources in accor-dance with task dependencies to ensure the smooth completion of the entire *** scheduling must consider an array of factors,including task dependencies,availability of computational resources,and the schedulability of ***,this paper delves into the distributed graph database workflow task scheduling problem and proposes a workflow scheduling methodology based on deep reinforcement learning(DRL).The method optimizes the maximum completion time(makespan)and response time of workflow tasks,aiming to enhance the responsiveness of workflow tasks while ensuring the minimization of the *** experimental results indicate that the Q-learning Deep Reinforcement Learning(Q-DRL)algorithm markedly diminishes the makespan and refines the average response time within distributed graph database *** quantifying makespan,Q-DRL achieves mean reductions of 12.4%and 11.9%over established First-fit and Random scheduling strategies,***,Q-DRL surpasses the performance of both DRL-Cloud and Improved Deep Q-learning Network(IDQN)algorithms,with improvements standing at 4.4%and 2.6%,*** reference to average response time,the Q-DRL approach exhibits a significantly enhanced performance in the scheduling of workflow tasks,decreasing the average by 2.27%and 4.71%when compared to IDQN and DRL-Cloud,*** Q-DRL algorithm also demonstrates a notable increase in the efficiency of system resource utilization,reducing the average idle rate by 5.02%and 9.30%in comparison to IDQN and DRL-Cloud,*** findings support the assertion that Q-DRL not only upholds a lower average

关键词： Reinforcement learning workflow task scheduling load balancing

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航空发动机故障诊断技术综述

沈阳航空工业学院学报 2007年第2期24卷 11-14页

作者：王英沙云东沈阳航空工业学院飞行器动力与能源工程学院辽宁沈阳110034

航空发动机故障诊断技术对避免飞行事故和降低飞行器运行成本是非常重要的。总结了航空发动机故障诊断的一些的方法,通过对各种方法的比较,对某种故障可以按照需要选择使用一种或几种方法。最后还介绍了目前较为前沿的两种故障诊断方法... 详细信息

航空发动机故障诊断技术对避免飞行事故和降低飞行器运行成本是非常重要的。总结了航空发动机故障诊断的一些的方法,通过对各种方法的比较,对某种故障可以按照需要选择使用一种或几种方法。最后还介绍了目前较为前沿的两种故障诊断方法:小波分析法和神经网络法。

关键词：航空发动机故障诊断小波分析神经网络

基于快速ICA的复杂路径下滚棒轴承外圈划伤故障特征提取

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机械设计与制造 2021年第12期370卷 77-81,87页

作者：王立炜栾孝驰沙云东袁琳沈阳航空航天大学航空发动机学院辽宁省航空推进系统先进测试技术重点实验室辽宁沈阳110136

针对航空发动机复杂路径下轴承故障难识别的问题,提出了基于快速独立分量分析的盲源分离理论与包络谱分析方法相结合的轴承故障诊断方法。为了模拟故障轴承振动信号的复杂传递路径,设计并加工了花键衬套连接方式、双层轴承结构的多层复... 详细信息

针对航空发动机复杂路径下轴承故障难识别的问题,提出了基于快速独立分量分析的盲源分离理论与包络谱分析方法相结合的轴承故障诊断方法。为了模拟故障轴承振动信号的复杂传递路径,设计并加工了花键衬套连接方式、双层轴承结构的多层复杂传递路径轴承故障膜拟实验台。在该实验台上开展了多工况下的滚棒轴承典型故障实验,应用本文提出的轴承故障诊断方法对轴承外圈划伤故障进行了深入分析处理,并将其与传统频谱分析及包络谱分析结果相比较。分析结果表明:盲源分离包络谱分析方法对复杂路径下滚棒轴承外圈故障诊断十分有效,诊断效果明显优于传统轴承故障诊断分析方法。

关键词：复杂路径滚棒轴承快速独立分量盲源分离包络变换

Clinical study of different prediction models in predicting diabetic nephropathy in patients with type 2 diabetes mellitus

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World Journal of Diabetes 2024年第1期15卷 43-52页

作者： sha-sha Cai Teng-Ye Zheng Kang-Yao Wang Hui-Ping Zhu Department of Nephrology The First People’s Hospital of WenlingWenling 317500Zhejiang ProvinceChina

BACKGROUND Among older adults,type 2 diabetes mellitus(T2DM)is widely recognized as one of the most prevalent *** nephropathy(DN)is a frequent com-plication of DM,mainly characterized by renal microvascular *** detection,aggressive prevention,and cure of DN are key to improving *** a diagnostic and predictive model for DN is crucial in auxiliary *** To investigate the factors that impact T2DM complicated with DN and utilize this information to develop a predictive *** The clinical data of 210 patients diagnosed with T2DM and admitted to the First People’s Hospital of Wenling between August 2019 and August 2022 were retrospectively *** to whether the patients had DN,they were divided into the DN group(complicated with DN)and the non-DN group(without DN).Multivariate logistic regression analysis was used to explore factors affecting DN in patients with *** data were randomly split into a training set(n=147)and a test set(n=63)in a 7:3 ratio using a random *** training set was used to construct the nomogram,decision tree,and random forest models,and the test set was used to evaluate the prediction performance of the model by comparing the sensitivity,specificity,accuracy,recall,precision,and area under the receiver operating characteristic *** Among the 210 patients with T2DM,74(35.34%)had *** validation dataset showed that the accuracies of the nomogram,decision tree,and random forest models in predicting DN in patients with T2DM were 0.746,0.714,and 0.730,*** sensitivities were 0.710,0.710,and 0.806,respectively;the specificities were 0.844,0.875,and 0.844,respectively;the area under the receiver operating characteristic curve(AUC)of the patients were 0.811,0.735,and 0.850,*** Delong test results revealed that the AUC values of the decision tree model were lower than those of the random forest and nomogram models(P<0.05),whereas the differ

关键词： Type 2 diabetes mellitus Diabetic nephropathy Random forest Decision-making tree Nomogram Forecast

Intraplantar Injection of Monosodium Iodoacetate Produces Hyperalgesia in Rats and the Mechanism Underlying the Effect

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Journal of Biosciences and Medicines 2024年第6期12卷 244-254页

作者： sha-sha Li Tian-yun Yao Dan Wu Li-Ting Nan Shuang-Quan Yu Graduate School Youjiang Medical University for Nationalities Baise China Department of Physiology School of Basic Medical Sciences Youjiang Medical University for Nationalities Baise China

Objective: To observe the effect of intraplantar injection of monosodium iodoacetate (MIA) on pain perception in rats and to investigate the role of transient receptor potential vanilloid type 1 (TRPV1) in the effect. Methods: Adult male Wistar rats were used in the experiment. 1) MIA was injected subcutaneously into the right hindpaw of rats, the low, medium, and high doses of MIA were 0.11, 0.33, and 1 mg, respectively, then the changes of paw withdrawal thermal latency, paw withdrawal mechanical threshold, and dynamic weight bearing within 4 hours after MIA injection were measured. 2) Capsazepine (TRPV1 antagonist, 30 μg) was injected subcutaneously into the right hindpaw of rats at 2 hours after intraplantar injection of MIA (1 mg), then the changes of paw withdrawal thermal latency, paw withdrawal mechanical threshold, and dynamic weight bearing within 1 hour after capsazepine injection were measured. Results: 1) The paw withdrawal thermal latency, paw withdrawal mechanical threshold, and dynamic weight bearing decreased after intraplantar injection of MIA in rats and the effect lasted for at least 4 hours. 2) The MIA-induced reduction in paw withdrawal thermal latency, paw withdrawal mechanical threshold, and dynamic weight bearing were significantly alleviated after intraplantar injection of capsazepine in rats. Conclusion: Intraplantar injection of MIA can produce thermal pain, mechanical pain, and spontaneous pain for more than 4 hours, which may be due to the TRPV1 activation caused by MIA.

关键词： TRPV1 Monosodium Iodoacetate Capsazepine Hyperalgesia

A Web-like Three-dimensional Binder for Silicon Anode in Lithium-ion Batteries

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Energy & Environmental Materials 2024年第1期7卷 21-27页

作者： Liyuan Li Tao Li Yifan sha Baozeng Ren Lan Zhang Suojiang Zhang CAS Key Laboratory of Green Process and Engineering Beijing Key Laboratory of Ionic Liquids Clean ProcessState Key Laboratory of Multiphase Complex SystemsInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemical Engineering Zhengzhou UniversityZhengzhou 450001China Langfang Green Industrial Technology Center Langfang 065001China Henan Key Laboratory of Energy Storage Materials and Processes Zhengzhou Institute of Emerging Industrial TechnologyZhengzhou 450003China

Si anode is of paramount importance for advanced energy-dense lithium-ion batteries(LIBs).However,the large volume change as well as stress generates during its lithiation-delithiation process poses a great challenge to the long-term cycling and hindering its *** this work,a composite binder is prepared with a soft component,guar gum(GG),and a rigid linear polymer,anionic polyacrylamide(APAM).Rich hydroxy,carboxyl,and amide groups on the polymer chains not only enable intermolecular crosslinking to form a web-like binder,A2G1,but also realize strong chemical binding as well as physical encapsulating to Si *** resultant electrode shows limited thickness change of merely 9%on lithiation and almost recovers its original thickness on *** demonstrates high reversible capacity of 2104.3 mAh g^(-1)after 100 cycles at a current density of 1800 mA g^(-1),and in constant capacity(1000 mAh g^(-1))test,it also shows a long life of 392 ***,this soft-hard combining web-like binder illustrates its great potential in the future applications.

关键词： anionic polyacrylamide lithium-ion batteries Si anode thickness change web-like binder

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复合材料轴结构力学性能预测及铺层方案设计

材料科学与工程学报 2016年第2期34卷 251-256,300页

作者：沙云东骆丽贾秋月赵奉同栾孝驰沈阳航空航天大学辽宁省航空推进系统先进测试技术重点实验室辽宁沈阳110136

针对连续纤维增强金属基复合材料轴结构力学性能预测问题,考虑纤维呈四边形和六角形两种周期性排列方式,基于细观力学有限元方法,建立六种代表体积元(RVE)模型,计算该材料的宏观力学性能参数,并与已有的三种细观力学模型计算结果进行对... 详细信息

针对连续纤维增强金属基复合材料轴结构力学性能预测问题,考虑纤维呈四边形和六角形两种周期性排列方式,基于细观力学有限元方法,建立六种代表体积元(RVE)模型,计算该材料的宏观力学性能参数,并与已有的三种细观力学模型计算结果进行对比分析。在此基础上,以低压涡轮轴为研究对象,将选定的RVE模型预测所得的宏观力学性能参数应用于该纤维增强复合材料轴结构的铺层方案设计中,利用数值模拟方法计算该轴结构在给定弯矩、扭矩作用下的变形量和应力,并分析铺层角度、厚度及铺层顺序对轴结构抗弯、抗扭性能的影响规律。研究发现纤维按某种特定的铺层角度组合铺设,可有效提高轴结构的抗弯、抗扭性能,通过计算分析提出了铺层设计方案。

关键词：连续纤维增强金属基复合材料细观力学模型低压涡轮轴力学性能铺层方案

Scattering of Water Waves by Dual Symmetric Inclined Floating Porous Barriers Using the DBEM

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China Ocean Engineering 2024年第1期38卷 156-168页

作者： WANG Li-xian DENG Yan-wen YE Yang-sha DENG Zheng-zhi Key Laboratory of High Performance Ship Technology(Wuhan University of Technology) Ministry of EducationWuhan 430063China School of Naval Architecture Ocean and Energy Power EngineeringWuhan University of TechnologyWuhan 430063China Key Laboratory of Water-Sediment Sciences and Water Disaster Prevention of Hunan Province Changsha 410114China Institute of Port Coastal and Offshore EngineeringZhejiang UniversityZhoushan 316021China

The scattering of normally incident water waves by two surface-piercing inclined perforated barriers in water with a uniform finite depth is investigated within the framework of linear water wave *** that thin barriers are zero-thickness,a novel numerical method involving the the coupling of the dual boundary element method(DBEM)with damping layers is *** order to effectively damp out the reflected waves,two damping layers,instead of pseudoboundaries are implemented near the two side boundaries of the computational ***,the modified linearized free surface boundary conditions are formulated and used for solving both the ordinary boundary integral equation as well as the hypersingular boundary integral equation for degenerate *** newly developed numerical method is validated against analytical methods using the matched eigenfunction expansion method for the special case of two vertical barriers or the inclined angle to the vertical being *** influence of the length of the two damping layers has been ***,these findings are also validated against previous results for several *** validation,the numerical results for the reflection coefficient,transmission coefficient and dissipation coefficient are obtained by varying the inclination angle and porosity-effect *** effects of both the inclination angle and the porosity on the amplitudes of wave forces acting on both the front and rear barriers are also *** is found that the effect of the inclination angle mainly shifts the location of the extremal values of the reflection and the transmission ***,a moderate value of the porosity-parameter is quite effective at dissipating wave energy and mitigating the wave loads on dual barriers.

关键词： dual boundary element method inclined perforated floating breakwater reflection coefficient transmission coefficient damping layer