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Hierarchical Hypergames and Bayesian Games:A Generalization of the Theoretical Comparison of Hypergames and Bayesian Games Considering Hierarchy of Perceptions

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Journal of Systems Science & Complexity 2016年第1期29卷 187-201页

作者： sasaki Yasuo KIJIMA Kyoichi School of Knowledge Science Japan Advanced Institute of Science and Technology 1-1AsahidaiNomiIshikawaJapan Department of Value and Decision Science Tokyo Institute of Technology 2-12-1OokayamaMeguro-kuTokyoJapan

This paper discusses the relationship of two independently developed models of games with incomplete information,hierarchical hypergames and Bayesian *** can be considered as a generalization of the previous study on the theoretical comparison of simple hypergames and Bayesian games(sasaki and Kijima,2012) by taking into account hierarchy of perceptions,i.e.,an agent's perception about the other agents' perceptions,and so *** authors first introduce the general way of transformation of any hierarchical hypergames into corresponding Bayesian games,which was called as the Bayesian representation of hierarchical *** authors then show that some equilibrium concepts for hierarchical hypergames can be associated with those for Bayesian games and discuss implications of the results.

关键词： Bayesian games game theory hierarchy of perceptions hypergames incomplete information

Mechanism Underlying Increase of the Serum Magnesium Concentration Observed Following Treatment with Sodium-Glucose Cotransporter 2 Inhibitors

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Journal of Diabetes Mellitus 2017年第4期7卷 241-248页

作者： Yasuhiro sasaki keiko Koyano Shuhei Iida Tatsuo Yanagawa Department of Medicine Nerima General Hospital Tokyo Japan Public Interest Incorporated Foundation Tokyo Healthcare Foundation Institute for Healthcare Quality Improvement Tokyo Japan

Aim: The EMPA-REG OUTCOME study reported that the sodium-glucose cotransporter 2 inhibitor (SGLT2-i) suppressed cardiovascular (CV) events in patients with type 2 diabetes;we recently suggested that increase of the serum magnesium (Mg) by SGLT2-i’s can, in part, explain this reduction. The objective of this study was to elucidate the mechanism underlying the elevation of the serum Mg level induced by treatment with SGLT2-i’s. Methods: We analyzed the data of 37 patients with type 2 diabetes who underwent clinical evaluation and laboratory assessment at baseline and the end of 3 months. To investigate the relationship between the changes in the serum Mg concentrations during 3 months’ treatment (ΔMg) and other variables, we carried out simple linear regression analysis and multiple linear regression analysis. Results: Three months’ treatment with the SGLT2-i resulted in a significant improvement of the body weight (BW), BMI, hemoglobin A1c (HbA1c), and fasting plasma glucose levels. The serum Mg increased significantly. Simple linear regression analysis revealed an association between the ΔMg and the serum triglyceride, serum Mg at baseline, change of the BW (ΔBW), and change of the HbA1c. Multiple linear regression analysis revealed a significant association between the ΔMg and the serum Mg level at the baseline (r = -0.55, P Conclusion: Our study revealed that a lower serum Mg level at the baseline and BW reduction were significantly associated with an increase in the serum Mg following 3 months’ treatment with SGLT2-i’s.

关键词： Diabetes Magnesium Cardiovascular Events Sodium-Glucose Cotransporter 2 Inhibitors The EMPA-REG OUTCOME Study

Population synthesis of planet formation using a torque formula with dynamic effects

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Geoscience Frontiers 2017年第2期8卷 215-222页

作者： Takanori sasaki Toshikazu Ebisuzaki Department of Astronomy Kyoto University RIKEN

Population synthesis studies into planet formation have suggested that distributions consistent with observations can only be reproduced if the actual Type Ⅰ migration timescale is at least an order of magnitude longer than that deduced from linear *** past studies considered the effect of the Type I migration of protoplanetary embryos,in most cases they used a conventional formula based on static torques in isothermal disks,and employed a reduction factor to account for uncertainty in the mechanism ***,in addition to static torques,a migrating planet experiences dynamic torques that are proportional to the migration *** dynamic torques can impact on planet migration and predicted planetary *** this study,we derived a new torque formula for Type Ⅰ migration by taking into account dynamic *** formula was used to perform population synthesis simulations with and without the effect of dynamic *** many cases,inward migration was slowed significantly by the dynamic *** the static torque case,gas giant formation was effectively suppressed by Type I migration;however,when dynamic effects were considered,a substantial fraction of cores survived and grew into gas giants.

关键词： Planetary formation Population synthesis Type Ⅰ migration

Highly active and stable supported Pd catalysts on ionic liquidfunctionalized SBA-15 for Suzuki–Miyaura cross-coupling and transfer hydrogenation reactions

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Green Energy & Environment 2019年第2期4卷 180-189页

作者： Etty N.Kusumawati Takehiko sasaki Department of Chemistry Graduate School of Science The University of Tokyo Institute for Catalysis Hokkaido University Department of Complexity Science and Engineering Graduate School of Frontier Sciences The University of Tokyo

Highly dispersed palladium nanoparticles were synthesized in the presence of immobilized ionic liquid on mesoporous silica ***(2.4 nm)_me-Im@SBA-15 catalyst was prepared by the reduction using NaBH_4 as the reducing agent with controlled feed rate and has been investigated as ligand-free catalyst for Suzuki–Miyaura cross-coupling reaction at room temperature in aqueous solution under *** catalyst was also prepared in situ from PdCl4_me-Im@SBA-15 during the reaction and demonstrated high activity and stability towards nitrobenzene hydrogenation at high temperature. Both catalysts were reusable at least for four recycle processes without significant loss in activity with simple procedure. The catalysts were characterized by TEM, EXAFS, FTIR and XPS.

关键词： Palladium nanoparticle Ionic liquid SBA-15 Suzuki–Miyaura cross-coupling Hydrogenation

BO_(2)-F^(+)Centers in the Radiation-damaged YCOB Crystals

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Chinese Physics Letters 2000年第12期17卷 896-898页

作者： RUAN Yong-Feng Hiroshi NAKAO Takatomo sasaki Department of Physics Tianjin UniversityTianjin 300072 Department of Electrical Engineering Osaka UniversityOsaka 565-0871Japan

An intense paramagnetic EPR signal generated from x-ray-irradiated,powdered YCOB crystals was observed at the liquid nitrogen temperature for the first *** peaks,located at the positions where the effective g factor equals to 1.992,1.986,1.980,1.974 and 1.965,labeled as A,B,C,D and E respectively,were *** is believed that the peaks A,B,C and D generated from the BO_(2)-F^(+)center which is a single electron trapped in an oxygen vacancy which was originally occupied by an O^(2-)ion bonded to a(BO3)^(3-)anion *** peak E is thought of coming from Y2+ions that are formed by the Y^(3+) ions trapping *** mechanism for the formation of the radiation-induced defects in the YCOB crystals is suggested.

关键词： Crystal occupied trapping

Expression of leukotriene B4 receptor 1 defines functionally distinct DCs that control allergic skin inflammation

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Cellular & Molecular Immunology 2021年第6期18卷 1437-1449页

作者： Tomoaki Koga Fumiyuki sasaki Kazuko Saeki Soken Tsuchiya Toshiaki Okuno Mai Ohba Takako Ichiki Satoshi Iwamoto Hirotsugu Uzawa keiko Kitajima Chikara Meno Eri Nakamura Norihiro Tada Yoshinori Fukui Junichi Kikuta Masaru Ishii Yukihiko Sugimoto Mitsuyoshi Nakao Takehiko Yokomizo Department of Biochemistry Juntendo University Graduate School of MedicineTokyo113-8421Japan Department of Medical Cell Biology Institute of Molecular Embryology and GeneticsKumamoto UniversityKumamoto860-0811Japan Department of Cell Signaling Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityTokyo113-8510Japan Department of Pharmaceutical Biochemistry Graduate School of Pharmaceutical SciencesKumamoto UniversityKumamoto862-0973Japan Department of Developmental Biology Graduate School of Medical SciencesKyushu UniversityFukuoka812-8582Japan Laboratory of Genome Research Research Institute for Diseases of Old AgeJuntendo University Graduate School of MedicineTokyo113-8421Japan Division of Immunogenetics Department of Immunobiology and NeuroscienceMedical Institute of BioregulationKyushu UniversityFukuoka812-8582Japan Department of Immunology and Cell Biology Graduate School of Medicine and Frontier BiosciencesOsaka UniversityOsaka565-0871Japan

Leukotriene B4(LTB4)receptor 1(BLT1)is a chemotactic G protein-coupled receptor expressed by leukocytes,such as granulocytes,macrophages,and activated T *** there is growing evidence that BLT1 plays crucial roles in immune responses,its role in dendritic cells remains largely ***,we identified novel DC subsets defined by the expression of BLT1,namely,BLT1hi and BLT1lo *** also found that BLT1hi and BLT1lo DCs differentially migrated toward LTB4 and CCL21,a lymph node-homing chemoattractant,*** generating LTB4-producing enzyme LTA4H knockout mice and CD11c promoter-driven Cre recombinase-expressing BLT1 conditional knockout(BLT1 cKO)mice,we showed that the migration of BLT1hi DCs exacerbated allergic contact *** transcriptome analysis revealed that BLT1hi DCs preferentially induced Th1 differentiation by upregulating IL-12p35 expression,whereas BLT1lo DCs accelerated T cell proliferation by producing ***,the data reveal an unexpected role for BLT1 as a novel DC subset marker and provide novel insights into the role of the LTB4-BLT1 axis in the spatiotemporal regulation of distinct DC subsets.

关键词： LTB4 BLT1 dendritic cells inflammation lipid mediator

Fibroblasts, an inconspicuous but essential player in colon cancer development and progression

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World Journal of Gastroenterology 2016年第23期22卷 5301-5316页

作者： Naofumi Mukaida Soichiro sasaki Division of Molecular Bioregulation Cancer Research InstituteKanazawa University

Tumor microenvironments have a crucial role in cancer initiation and progression, and share many molecular and pathological features with wound healing process. Unless treated, tumors, however, do not heal in contrast to wounds that heal within a limited time framework. Wounds heal in coordination of a myriad of types of cells, particularly endothelial cells, leukocytes, and fibroblasts. Similar sets of cells also contribute to cancer initiation and progression, and as a consequence, anti-cancer treatment strategies have been proposed and tested by targeting endothelial cells and/or leukocytes. Compared with endothelial cells and leukocytes, less attention has been paid to the roles of cancer-associated fibroblasts(CAFs), fibroblasts present in tumor tissues, because their heterogeneity hinders the elucidation on them at cellular and molecular levels. Here, we will discuss the origin of CAFs and their crucial roles in cancer initiation and progression, and the possibility to develop a novel type of anti-cancer treatment by manipulating the migration and functions of CAFs.

关键词： Angiogenesis Drug resistance Extracellular matrix Immune evasion Transforming growth factor-β Invasion Metastasis

A minimized fluorescent chemosensor array utilizing carboxylate-attached polythiophenes on a chip for metal ions detection

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Frontiers of Chemical Science and Engineering 2022年第1期16卷 72-80页

作者： Yui sasaki Xiaojun Lyu Zhoujie Zhang Tsuyoshi Minami Institute of Industrial Science The University of TokyoTokyo 153-8505Japan

Chemosensor arrays have a great potential for on-site applications in real-world ***,to fabricate on chemosensor array a number of chemosensors are required to obtain various optical patterns for multianalyte ***,we propose a minimized chemosensor array composed of only two types of carboxylate-functionalized polythiophene derivatives for the detection of eight types of metal *** recognition of the metal ions,the polythiophenes exhibited changes in their fluorescence intensity and various spectral *** both chemosensors have the same polymer backbone and recognition moiety,only the difference in the number of methylene groups contributed to the difference in the fluorescence response ***,the metal ions in aqueous media were successfully discriminated qualitatively and quantitatively by the chemosensor microarray on the glass *** study offers an approach for achieving a minimized chemosensor array just by changing the alkyl chain lengths without the necessity for many receptors and reporters.

关键词： metal ions polythiophene chemosensor array fluorescence pattern recognition

Estimating Vertical Distribution of Vegetation Cover in Temperate Heterogeneous Forests Using Airborne Laser Scanning Data

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Open Journal of Forestry 2012年第3期2卷 89-96页

作者： keiko Ioki Junichi Imanishi Takeshi sasaki Youngkeun Song Yukihiro Morimoto Hisashi Hasegawa Field Science Education and Research Center Kyoto University Kyoto Japan Graduate School of Agriculture Kyoto University Kyoto Japan Graduate School of Global Environmental Studies Kyoto University Kyoto Japan

Vertical structure is important for understanding forest environment, yet difficult to characterize, especially in temperate heterogeneous forests where the structure is complex. This study used data from a small-footprint airborne laser scanning (ALS) to estimate vegetation coverage in four stratum ranges in a warm temperate forest in Japan: >12 m, 8 - 12 m, 4 - 8 m, and 0 - 4 m in height. Field data were collected in 17 broad-leaved and 12 coniferous sample plots, consisting of the proportion of vegetation cover in each stratum range. The field and ALS measurements were conducted in summer, during leaf-on conditions. Using echo attributes (first, last, intermediate, and only), we calculated the vegetation coverage index (VCI) at 1-m height intervals. The cumulative sum of the VCI (CUMVCI) was then computed and compared with field observations. Linear regression analysis showed that the ALS data gave reasonable estimates of vegetation coverage in the upper two or three stratum ranges in broad-leaved stands, and in the upper two stratum ranges in coniferous stands. The model gave reproducible estimates until approximately 95% of the total returns had been applied. We conclude that ALS data can provide useful information on natural habitats in the management of warm temperate forest.

关键词： Forest Structure Remote Sensing Airborne Laser Scanning