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基于生物标志物和微流控技术的脓毒症早期诊断研究进展

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实用医院临床杂志 2024年第4期21卷 33-38页

作者：郭雪艳邓兆凯桑岭广州医科大学附属第一医院重症医学科广州呼吸健康研究院广东广州510120

脓毒症已成为全球公共健康领域的一个重大难题。由于其初始体征和症状具有非特异性,且缺乏足够敏感或特异的诊断评分系统及生物标志物,患者往往未能接受及时诊断和治疗,死亡率极高。因此,早期识别脓毒症并进行及时干预尤为重要,新型的... 详细信息

脓毒症已成为全球公共健康领域的一个重大难题。由于其初始体征和症状具有非特异性,且缺乏足够敏感或特异的诊断评分系统及生物标志物,患者往往未能接受及时诊断和治疗,死亡率极高。因此,早期识别脓毒症并进行及时干预尤为重要,新型的脓毒症相关分子和生物标志物值得进一步深入研究。本文综述脓毒症的主要诊断方法,包括临床评估、生物标志物及新兴的诊断技术,旨在为临床工作者提供全面的参考。

关键词：脓毒症早期诊断生物标志物组学微流控

Genetic analysis and gene mapping of a dominant presenescing leaf gene PSL3 in rice (Oryza sativa L.)

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Chinese Science Bulletin 2010年第23期55卷 2517-2521页

作者： FANG LiKui LI YunFeng GONG XiaoPing sang XianChun ling YingHua WANG XiaoWen CONG YunFei HE GuangHua Rice Research Institute Key Laboratory of Biotechnology and Crop Quality Improvement Ministry of Agriculture Southwest University Chongqing 400716 China

Leaf senescence as an active process is essential for plant survival and ***,premature senility is harmful to agricultural *** this study,a rice mutant,named as psl3 (presescing leaf 3) isolated from EMS-treated Jinhui 10,displays obvious premature senility features both in morphological and physiological *** analysis showed that mutant trait was controlled by a single dominant gene (PSL3),which was located on rice chromosome 7 between SSR marker c7sr1 and InDel marker ID10 with an interval of 53.5 *** result may be useful for the isolation of the PSL3 gene.

关键词：水稻叶片遗传分析基因定位早衰 SSR标记基因分离叶片衰老农业生产

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市场环境、参股银行业与企业银行贷款

系统工程理论与实践 2020年第4期40卷 863-874页

作者：解维敏桑凌东北财经大学会计学院大连116025 东北财经大学中国内部控制研究中心大连116025

本文以2007-2016年我国A股非金融类上市公司为样本,理论分析和实证检验了地区市场环境对企业参股银行业的影响,并进一步考察了参股银行业对企业银行贷款的影响.研究结果表明,地区市场环境影响了企业参股银行业的意愿和行为,在市场环境... 详细信息

本文以2007-2016年我国A股非金融类上市公司为样本,理论分析和实证检验了地区市场环境对企业参股银行业的影响,并进一步考察了参股银行业对企业银行贷款的影响.研究结果表明,地区市场环境影响了企业参股银行业的意愿和行为,在市场环境较差的地区,企业更有可能选择参股银行业.与没有参股银行业的企业相比,参股银行业的企业能够获得更多的银行贷款,而且其贷款成本更低.进一步研究发现,参股银行业对企业银行贷款的影响,在那些处于市场环境较差地区的企业中体现得更为明显.本文研究结论揭示了在市场环境不完善的制度背景下,企业建立与银行之间的股权关联的行为动机和经济后果.

关键词：市场环境企业参股银行业银企关系银行贷款

Interplay of Coexisting Odd-Order Wave Mixings in a Five-Level Atomic System

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Chinese Physics Letters 2011年第2期28卷 101-104页

作者： SONG Yue HUO Shu-Li LI Pei-Ying sang Su-ling WANG Zhi-Guo ZHANG Yan-Peng Key Laboratory for Physical Electronics and Devices of the Ministry of Education&Shaanxi Key Lab of Information Photonic Technique Xi’an Jiaotong UniversityXi’an 710049

We experimentally investigate the interplay between two coexisting six-wave mixing(SWM)signals and the interference between coexisting four-wave mixing(FWM)and SWM signals in a five-level atomic system of85 *** two electromagnetically induced transparency windows gradually overlap in frequency,the competition between these two SWM signals ***,we report the experimental result which shows that the temporal interference with femtosecond time scales between FWM and SWM signals.

关键词： mixing transparency overlap

新型电动哮喘辅助给药装置创新设计与实验研究

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机电产品开发与创新 2024年第3期37卷 41-44,56页

作者：桑凌峰张赏赏岑大卫陶靖李昱磊黄晓春宁波职业技术学院智能医疗养老护理技术研究所浙江宁波315800 浙江佑仁智能机器人有限公司浙江宁波315800

基于哮喘患者用药过程中手口协同难度高、药剂剩余次数不清晰等问题,设计了一款新型电动哮喘辅助给药装置。首先,提出了负压触发工作原理,对给药装置运动机构进行设计,并对关键构件电动推杆进行了计算和选型;其次,将给药装置分为主体结... 详细信息

基于哮喘患者用药过程中手口协同难度高、药剂剩余次数不清晰等问题,设计了一款新型电动哮喘辅助给药装置。首先,提出了负压触发工作原理,对给药装置运动机构进行设计,并对关键构件电动推杆进行了计算和选型;其次,将给药装置分为主体结构和药剂快装结构,并对其进行了详细的结构设计;之后,搭建了该装置的控制系统,对升压电路、降压电路以及电池容量进行了详细的设计和计算;最后,研制了该装置的物理样机,通过模糊评价法测试了该结构的操作便捷性,图像法对比法测试了给药装置的给药准确性,相机跟踪法测试了该装置的喷射时间,从实验效果来看,该装置的操作便捷性表现优秀,给药准确性达到了97.43%,喷射反应时间为0.85s,能够满足患者需求。

关键词：电动哮喘辅助给药装置负压触发结构设计控制系统设计

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Genetic analysis and molecular mapping of a novel gene for zebra mutation in rice (Oryza sativa L.)

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Journal of Genetics and Genomics 2009年第11期36卷 679-684页

作者： Qiushi Wang,Xianchun sang,Yinghua ling,Fangming Zhao,Zhenglin Yang,Yunfeng Li,Guanghua He Key Laboratory of Biotechnology and Crop Quality Improvement,Ministry of Agriculture Rice Research Institute,Southwest University,Chongqing 400716,China Key Laboratory of Biotechnology and Crop Quality Improvement Ministry of Agriculture Rice Research Institute Southwest University Chongqing 400716 China

A novel zebra mutant, zebra-15, derived from the restorer line JinhuilO （Oryza sativa L. ssp. indica） treated by EMS, displayed a distinctive zebra leaf from seedling stage to jointing stage. Its chlorophyll content decreased （55.4%） and the ratio of Chla/Chlb increased （90.2%） significantly in the yellow part of the zebra-15, compared with the wild type. Net photosynthetic rate and fluorescence kinetic parameters showed that the decrease of chlorophyll content significantly influenced the photosynthetic efficiency of the mutant. Genetic analysis of F2 segregation populations derived from the cross of XinonglA and zebra-15 indicated that the zebra leaf trait is controlled by a single recessive nuclear gene. Ninety-eight out of four hundred and eighty pairs of SSR markers showed the diversity between the XinonglA and the zebra-15, their F2 population was then used for gene mapping. Zebra-15 （Z-15） gene was primarily restricted on the short arm of chromosome 5 by 150 F2 recessive individuals, 19.6 cM from marker RM3322 and 6.0 cM from marker RM6082. Thirty-six SSR markers were newly designed in the restricted location, and the Z-15 was finally located between markers nSSR516 and nSSR502 with the physical region 258 kb by using 1,054 F2 recessive individuals.

关键词： molecular mapping rice (Oryza sativa L.) zebra mutant chlorophyll Zebra-15

Dynamic recrystallization mechanism, texture evolution development and mechanical characteristics of a Mg–8.7Gd–4.18Y–0.42Zr magnesium alloy by ECAP

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Progress in Natural Science:Materials International 2024年第2期34卷 376-388页

作者： ling Zhang Yinglong Li School of Materials Science and Engineering Northeastern University School of Mechanical and Engineering Ningxia Institute of Science and Technology

Equal channel angle pressing is recognized for its ability to refine alloy grains and alter grain orientation, thereby achieve better mechanical performance of the magnesium alloy. This study investigates the microstructures,dynamic recrystallization mechanism, texture development, and mechanical performance of GW94K(Mg–8.7Gd–4.18Y–0.42Zr wt. %) Mg alloy following ECAP-4 passes at 400°C and 3 mm/min. Results show that when high-temperature deformation is undertaken, twin formation is suppressed while dislocation slip is facilitated, increasing dislocation density during deformation. Following ECAP deformation, the sample displayed higher fracture elongation, TYS, and UTS than the as-solutioned GW94K alloy. In particular, the GW94K alloy performed well mechanically after ECAP-4 passes, with an ultimate TYS of 231 MPa, an UTS of 290 MPa, and an elongation of 14.8 %. DDRX and shear bands induce CDRX, both of which are important in plastic deformation. as well as in modifying microstructure and grain orientation during ECAP deformation.

关键词： Dynamic recrystallization mechanism Equal channel angular pressing Magnesium alloy Mechanical performance Mg-Gd-Y-Zr alloy Texture development

Eigenvalues for the Clamped Plate Problem of L_(ν)^(2) Operator on Complete Riemannian Manifolds

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Acta Mathematica Sinica,English Series 2024年第9期40卷 2223-2243页

作者： ling Zhong ZENG Jiangxi Provincial Center for Applied Mathematics&School of Mathematics and Statistics Jiangxi Normal UniversityNanchang 330022P.R.China

L_(ν) operator is an important extrinsic differential operator of divergence type and has profound geometric *** this paper,we consider the clamped plate problem of L_(ν)^(2)operator on a bounded domain of the complete Riemannian manifolds.A general formula of eigenvalues of L_(ν)^(2) operator is *** this general formula,we obtain some estimates for the eigenvalues with higher order on the complete Riemannian *** several fascinating applications,we discuss this eigenvalue problem on the complete translating solitons,minimal submanifolds on the Euclidean space,submanifolds on the unit sphere and projective *** particular,we get a universal inequality with respect to the L_(II) operator on the translating ***,it is very difficult to get universal inequalities for weighted Laplacian and even Laplacian on the complete Riemannian ***,this work can be viewed as a new contribution to universal estimate.

关键词： Mean curvature flows L_(ν)^(2)operator clamped plate problem eigenvalues Riemannian manifolds translating solitons

Enhancement and suppression of spatial splitting four-wave mixing in atomic medium

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Chinese Physics B 2012年第2期21卷 309-316页

作者： Zhuang Yu-Ming sang Su-ling Li Pei-Ying Yuan Chen-Zhi Huo Shu-Li Xue Xin-Xin Wang Zhi-Guo Zheng Huai-Bin Zhang Yan-Peng Key Laboratory for Physical Electronics and Devices of the Ministry of Education&Shaanxi Key Laboratory of Information Photonic Technique Xi'an Jiaotong UniversityXi'an 710049China School of Physics and Information Technology Ningxia Teachers UniversityGuyuan 756000China

We experimentally report on the evolution from singly-dressed to doubly-dressed four-wave mixing （FWM） process by controlling the powers of the probe, the pump and the dressing fields respectively. The differences in the enhancement and the suppression of FWM signal between the two-level and cascade three-level atomic systems are observed and explained by the multi-dressed effect theoretically. Both the x direction and the y direction spatial splittings of the degenerate-FWM （DWFM） beams are obtained. We also investigate the switch between the enhancement and the suppression of the DWFM signals and between its spatial splittings in x direction and y direction. The spatial splittings in x direction and y direction can be controlled by the relative position and the intensity of the involved laser beams. Such a study can be useful for optimizing the efficiency of the FWM process and providing potential applications in spatial signal processing.

关键词： four-wave mixing spatial splitting enhancement suppression