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The nature of the companion of PSR j.719-1438: a white dwarf or an exotic obj.ct?

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Research in Astronomy and Astrophysics 2012年第7期12卷 813-816页

作者： j. E. Horvath Instituto de Astronomia Geofísica e Ciências Atmosfricas - Universidade de So Paulo

We raise the possibility that the very dense, compact companion of PSR j.719-1438, which has a j.piter-like mass, is an exotic quark obj.ct rather than a light helium or carbon white dwarf. The exotic hypothesis naturally explains some of the observed features, and provides quite strong predictions for this system, to be confirmed or refuted in feasible future studies.

关键词： binary pulsars -- exotic matter-- pulsars: individual (PSR j.719-1438)

Ferritin acts as a target site for the snowdrop lectin （GNA） in the midgut of the cotton leafworm Spodoptera littoralis

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Insect Science 2008年第6期15卷 513-519页

作者： Amin sadeghi Guy Smagghe Paul Proost Els j.M. Van Damme Laboratory of Agrozoology Department of Crop Protection Laboratory of Biochemistry and Glycobiology Department of Molecular Biotechnology Faculty of Bioscience Engineering Ghent University Ghent Rega Institute Laboratory of Molecular Immunology Kathofieke Universiteit Leuven Minderbroedersstraat 10 B-3000 Leuven Belgium

The snowdrop lectin GNA （Galanthus nivalis agglutinin） has been shown to possess insecticidal activity to a range of economically important insect pests. However, the precise mechanism of insecticidal action of GNA against insects remains unknown. In this investigation, we attempted to purify and identify receptor（s） responsible for binding of GNA in the larval midgut of a maj.r lepidopteran pest （the cotton leafworm, Spodoptera littoralis） to better understand its mode of action. Therefore, cytoplasmic as well as membrane proteins from 800 larval midguts were chromatographed on a column with immobilized GNA. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis of the proteins eluted from the GNA column followed by sequencing of the GNA-binding proteins and BLAST analyses revealed that the N-terminal sequences of a 24 kDa polypeptide purified from the cytoplasmic and membrane protein fraction revealed sequence similarity to sequences encoding heavy chain homologs of ferritin from Manduca sexta （76% sequence identity）, Calpodes ethlius （80% sequence identity） and Bombyx mori （61% sequence identity）. Furthermore, the N-terminal sequence of a 31 kDa polypeptide from the membrane protein fraction showed sequence similarity to a light chain homolog of ferritin from Manduca sexta （88% sequence identity）.

关键词： ferritin Galanthus nivalis agglutinin GNA Lepidoptera midgut receptors Spodoptera littoralis

Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia S.Rex David j.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National Science Foundation(NSF),the NEI,the Blue Ridge Institute for Medical Research and data from the maj.r professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis

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Neural Regeneration Research 2025年第7期20卷 2013-2014页

作者： Nathanael j.Lee Ryota L.Matsuoka Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Molecular Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose and oxygen through its vascular *** vasculature consists of highly divergent blood vessel branches,giving rise to a dense network of capillaries that supply blood to all cells across the *** elaborated vascular network is thought to develop via angiogenesis,a process in which new blood vessels grow from pre-existing *** capillaries exhibit organotypic features distinct from other tissues and are formed primarily by two maj.r endothelial cell(EC)types:those that form the semi-permeable blood-brain barrier(BBB)and those that develop highly permeable pores known as fenestrae(Matsuoka et al.,2022).The structural and functional differences between BBB and fenestrated vascular ECs represent a fundamental feature of brain vasculature and form the foundation for both brain function and homeostasis.

关键词： angiogenesis homeostasis network

Enhanced viability and improved in situ antibacterial activity of the probiotic LAB microencapsulated layer-by-layer in alginate beads coated with nisin

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FOOD BIOSCIENCE 2023年第3期53卷 1025-1033页

作者： Zarali, Maryam sadeghi, Alireza j.fari, Seid Mahdi Ebrahimi, Maryam Mahoonak, Alireza sadeghi Gorgan Univ Agr Sci & Nat Resources Dept Food Sci & Technol Gorgan Iran Gorgan Univ Agr Sci & Nat Resources Dept Food Mat & Proc Design Engn Gorgan Iran Golestan Univ Med Sci Food Drug & Nat Prod Hlth Res Ctr Gorgan Iran

In the present study, a layer-by-layer technique was used to prepare alginate-nisin (Alg-N) as coating layer to encapsulate a potential probiotic-protective lactic acid bacteria (LAB) isolate in order to improve its both survival and antibacterial activities in situ. The isolate was identified as Pediococcus acidilactici according to the sequencing results of the PCR products. The mean size of Alg and Alg-N microcapsules was also equal to 762.63 and 501.77 mu m, respectively based on the results of field emission scanning electron microscopy. In accordance with the zeta potential data, the Alg-N surrounding layer was confirmed. Furthermore, the Fourier transform infrared findings revealed the adsorption of nisin on the Alg beads. The antibacterial activity of the produced microcapsule on Staphylococcus aureus (100% inhibition) was significantly (P < 0.05) higher than that of the other foodborne bacteria studied. In addition, enhanced viability of the microencapsulated LAB in simulated gastrointestinal conditions and flavored milk, as well as its improved in situ inhibitory effect on S. aureus were verified.

关键词： Layer-by-layer Alginate-nisin coating Enhanced survival In situ antibacterial

Synthesis and characterization of silica-supported Pd nanoparticles and its application in the Heck reaction

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Chinese Chemical Letters 2012年第8期23卷 887-890页

作者： Mehran Ghiaci Donya Valikhani Zahra sadeghi Department of Chemistry Isfahan University of Technology***Iran Department of Chemistry Payame Noor University19395-4697 TehranIran

Well-dispersed palladium nanoparticles immobilized onto modified silica （Si02-pr-NH-cyanuric-SH） have been prepared in some facile steps. The catalyst exhibits high catalytic activity in the Heck reaction, and can b... 详细信息

关键词： Nanoparticles Palladium Heck reaction

Calculations of ^(86)Y production via various nuclear reactions

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Nuclear Science and Techniques 2009年第6期20卷 369-372页

作者： sadeghi Mahdi ZALI Akram MOKHTARI Leila Agricultural Medical & Industrial Research School P.O. Box: 31485-498 Gohardast Karaj Iran Faculty of Engineering Research and Science Campus Islamic Azad University Tehran Iran Physics Faculty University of Zanjan P.O. Box: 45195/313 Zanjan Iran

This study obtains a suitable reaction to produce 86Y. The 86Y excitation functions via 86Sr(p,n)86Y, 86Sr(d,2n)86Y, 85Rb(3He,2n)86Y and 85Rb(α,3n)86Y reactions were calculated by TALYS-1.0 code and compared with the reported measurement. Requisite thickness of targets was obtained by SRIM code for each reaction. The 86Y production yield was evaluated with attention to excitation function and stopping power. The 86Sr(p,n)86Y reaction was determined as most interesting one due to its highest production yield and advantages to get high radionuclide and radiochemical purity.

关键词：核反应生产计算反应注射成型放射化学纯度放射性核素制动力激励

Evaluation of excitation function by TALYS code for producing ^(109)Cd with different ion beams

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Nuclear Science and Techniques 2009年第4期20卷 243-247页

作者： sadeghi Mahdi MIRZAII Mohammad GHOLAMZADEH Zohreh Agricultural Medical&Industrial Research SchoolNuclear Science and Technology Research Institute Faculty of Engineering Research and Science CampusIslamic Azad University

TALYS code was used to calculate excitation functions for proton induced onn atAg,natCd and 113In,deuteron induced onn atAg and alpha induced on natPd that lead to produce 109Cd radioisotope using low and medium energy accelerators;calculates was performed out up to 50 *** thickness of the targets according to SRIM code was *** integral yields for any reaction were *** 1.0 code predicts that production of a few curries of 109Cd is feasible using a target of high isotopically enriched 110Cd,proton energy of 15 to 27 MeV,however high cost of the enriched target seems to be not a practical economic alternative to produce1 *** Ag+p and Ag+d processes can be an efficient route and economic for the production of millicurries of the radioisotope with incident beam energy less 15 MeV using low energy accelerator.

关键词：离子衍射 SRIM 加速器理论

Explaining and evaluating the quality of“light”in religious environments and its effect on spirituality

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Frontiers of Architectural Research 2021年第4期10卷 803-820页

作者： Pietro Matracchi Ali sadeghi habibabad Department of Architecture(DIDA) University of FlorenceUNIFI(Universita`Degli Studi di Firenze)FlorenceItaly

The current study aimed to investigate the quality of the interior architecture of the religious spaces regarding inducing the sense of spirituality with an emphasis on ***,the authors introduced the best option by simulating the light intensity of the interior environment of the Nasir Al-Mulk Mosque,Shiraz,in software and developing a visual standard questionnaire with a statistical population including the *** research was a field,and survey study and computational software were used to simulate the light intensity of the interior environment of the mosque in the first ***,the researcher-made visual questionnaire was ***,this questionnaire was sent to the experts online due to the current situations due to the Covid-19 *** statistical population was selected using the purposive sampling method from the universities of Iran,Malaysia,India,and Turkey,whose expertise was architecture,environmental psychology,and sacred arts.

关键词： Islamic architecture Spirituality Tranquility Religious spaces Environmental psychology Light