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Dedicated siPM array for GRD of GECAM

Radiation Detection Technology and Methods 2022年第1期6卷 63-69页

作者： D.L.Zhang x.L.sun Z.H.An x.Q.Li x.Y.Wen K.Gong C.Cai Z.Chang G.Chen C.Chen Y.Y.Du M.Gao R.Gao D.Y.Guo J.J.He D.J.Hou Y.G.Li C.Y.Li G.Li L.Li x.F.Li M.s.Li x.H.Liang x.J.Liu Y.Q.Liu F.J.Lu H.Lu B.Meng W.x.Peng F.shi H.Wang J.Z.Wang Y.s.Wang H.Z.Wang x.Wen s.xiao s.L.xiong Y.B.xu Y.P.xu s.yang1 x.zhou J.W.yang Fan Zhang s.N.Zhang C.Y.Zhang C.M.Zhang Fei Zhang x.Y.Zhao Institute of High Energy Physics CASBeijing 100049China state Key Laboratory of Particle Detection and Electronics Beijing 100049China

Purpose The discovery of gravitational waves and gamma-ray bursts heralds the era of multi-messenger *** the adoption of two small satellites to achieve the all-sky monitoring of gamma-ray bursts,the gravitational wave highenergy electromagnetic counterpart all-sky monitor(GECAM)possesses a quasi-real-time early warning ability and plays an important role in positioning the sources of gravitational waves and in subsequent *** satellite of GECAM was fitted with 253-inch-diameter gamma-ray detectors(GRD),covering an energy range of 8–2 *** have adopted silicon photomultiplier tubes(siPM)in lieu of photomultiplier tubes(PMT)to adapt to the dimensional limitations of *** A unique 3-inch circular siPM array was *** this design,646×6 mm chips were arranged evenly in a circular manner with the seams filled with reflecting films,thus achieving satisfactory uniformity of light *** integrated pre-amplifier circuit on the back of the siPM array adopted two-level grouping and summing;further,it achieved a satisfactory signal-to-noise *** high-gain and low-gain channels were adopted to achieve a large dynamic range,and two independent power supply units were used,where each unit can be closed separately,thus improving *** Performance studies show that this siPM array meets the requirements of *** A 3-inch siPM array have been developed that uses grouped summation,reflective films,a circular arrangement,two groups of independent power supplies,high-and low-gain signals,differential signal output technologies,*** solution can be used not only for GECAM,but also as a general solution for siPM-based scintillation detectors.

关键词： siPM GECAM Gamma-ray signal-to-noise ratio Reflecting film Pre-amplifier

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Intelligent feedforward gust alleviation based on neural network

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Chinese Journal of Aeronautics 2024年第3期37卷 116-132页

作者： Yitao zhou Zhigang WU Chao yang school of Aeronautic science and Engineering Beihang UniversityBeijing 100191China

This paper proposes a neural network-based intelligent feedforward gust alleviation framework,which includes a neural network identification model and a neural network controller.A neural network training dataset is formed by collecting flight data and the gust data encountered during the aircraft flight.A neural network identification model is first trained to accurately predict the aircraft’s ***,based on the output of the identification model and the collected flight data,the parameters of the time-delay neural network controller are obtained through a learning *** simulation results show that the designed intelligent controller has good gust alleviation effects for both continuous turbulence excitation and discrete gust *** example,when the aircraft is 40000 kg and the flight speed is 0.81Ma,the controller achieves a 67.82%reduction in wingtip acceleration and a 35.90%reduction in center of mass acceleration under continuous turbulence *** considering the measurement uncertainties,such as noise existing in the collected data,the trained controller can still achieve an acceptable gust alleviation ***,considering a flight in which the aircraft mass is constantly changing,the intelligent controller,which continuously learns from new flight data,maintains a good gust alleviation effect throughout the flight.

关键词： Gust alleviation Intelligent control Feedforward control Neural networks Time-varying aircraft

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Utilizing a metal-forging inspired chain combing strategy to enhance properties and expand applications of Nylon 66 plastic via heat inducing

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Nano Research 2024年第3期17卷 2164-2171页

作者： Junyu yang Jiangwei Zhang Nan Wang Guangyuan zhou Division of Energy Materials Daglian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China Innovation Center of Energy Material and Chemistry College of Chemistry and Chemical EngineeringInner Mongolia UniversityHohhot 010021China

The mechanical properties of engineering plastics can be enhanced through effective surface mechanical treatment(sMT),which can be applied to various types of engineering plastics,eliminating the limitations of conventional polymer processing and could potentially extend their applications and improve their performance and reliability as structural-functional *** by metal forging,this work proposes a simple and effective sMT strategy to enhance the mechanical properties of polyamide 66(PA66).Tensile tests have shown that sMTed PA66 samples exhibit significant improvements in both Young’s modulus and ultimate tensile strength(UTs),with a 2104 MPa Young’s modulus,almost double that of the pristine samples,and a 35.56%increase in UTs,reaching 183 ***,the modulus within the localized sMTed surface layer could reach up to 14 GPa,which is approximately 14 times higher than that of the pristine *** Vickers hardness within the localized sMTed surface layer can be doubled,reaching 10.72 Hv,and the crystallinity can increase by approximately 20%compared to the untreated ***,force field molecular dynamics(FFMD)simulations were conducted to investigate the ternary relationship between the sMT method,PA66’s molecular structure,and its *** combination of MD simulations and versatile structural characterizations provides evidence that the sMT method’s mechanism,under heat induction,results in a chain-combing procedure that changes the polymer’s molecular morphology microscopically and enhances its mechanical properties macroscopically.

关键词： Nylon 66 mechanical properties hardness crystallinity structural characterizations molecular dynamics simulation

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structural basis for polyuridine tract recognition by sARs-CoV-2 Nsp15

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Protein & Cell 2024年第7期15卷 547-552页

作者： Fumiaki Ito Hanjing yang Z.Hong zhou xiaojiang s.Chen Molecular and Computational Biology Department of Biological SciencesUniversity of Southern CaliforniaLos AngelesCA 90089United States Department of Microbiology Immunology and Molecular GeneticsUniversity of CaliforniaLos AngelesCA 90095United States California Nanosystems Institute University of CaliforniaLos AngelesCA90095United States Genetic Molecular and Cellular Biology ProgramKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90089United States Norris Comprehensive Cancer Center University of Southern CaliforniaLos AngelesCA 90089United States Center of Excellence in NanoBiophysics University of Southern CaliforniaLos AngelesCA 90089United States

Dear Editor,Coronaviruses have evolved a wide array of tactics to evade host antiviral *** host cells detect invading foreign nucleic acids including viral genome and viral replication intermediates,they activate interferon(IFN)signaling via cytoplasmic pattern recognition receptors(Kang et al.,2002;Kato et al.,2006).Remarkable stealth activities exhibited by coronaviruses are facilitated by a series of non-structural proteins(Nsps),such as Nsp15(Deng and Baker,2018;Deng et al.,2019;Hackbart et al.,2020),which is a uridine-specific endoribonuclease that mediates evasion of host detection of viral double-stranded RNA(dsRNA)(Bhardwaj et al.,2004;Deng et al.,2017;Frazier et al.,2021;Ivanov et al.,2004).Nsp15 targets a polyuridine[poly(U)]tract on the coronavirus negative strand RNA(Hackbart et al.,2020).Nsp15 limits the abundance and length of poly(U)within the negative strand RNA 5ʹ-extension by trimming down the initially synthesized poly(U)lead sequence to the optimal length that can suppress dsRNA formation but still serves as a template for poly(A)tail of the positive strand genome of the coronaviruses(Hofmann and Brian,1991).

关键词： p15 interferon template

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Recent advances in heterogeneous hydrosilylation of unsaturated carbon-carbon bonds

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Chinese Chemical Letters 2024年第6期35卷 71-85页

作者： Heng yang Zhijie zhou Conghui Tang Feng Chen school of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225002China Key Laboratory of Material Chemistry for Energy Conversion and storage Ministry of EducationHubei Key Laboratory of Material Chemistry and Service FailureSchool of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhan 430074China

The hydrosilylation of unsaturated carbon-carbon bonds is one of the most critical reactions in silicone industrial *** homogeneous speier's catalyst,Karstedt's catalyst,and other noble metal-based catalysts are widely ***,simplifying the separation of the homogeneous catalyst from reaction products and reducing the high cost of precious metals is still *** review describes the recent development of heterogeneous catalysts for alkene,alkyne,and allene hydrosilylations,which can effectively solve problems in homogeneous hydrosilylation.

关键词： Hydrosilylation Heterogeneous catalysis Alkenes Alkynes silanes

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Fabrication and integration of photonic devices for phase-change memory and neuromorphic computing

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International Journal of Extreme Manufacturing 2024年第2期6卷 2-27页

作者： Wen zhou xueyang shen xiaolong yang Jiangjing Wang Wei Zhang Center for Alloy Innovation and Design(CAID) State Key Laboratory for Mechanical Behavior of MaterialsXi’an Jiaotong UniversityXi’an 710049People’s Republic of China

In the past decade,there has been tremendous progress in integrating chalcogenide phase-change materials(PCMs)on the silicon photonic platform for non-volatile memory to neuromorphic in-memory computing *** particular,these non von Neumann computational elements and systems benefit from mass manufacturing of silicon photonic integrated circuits(PICs)on 8-inch wafers using a 130 nm complementary metal-oxide semiconductor *** manufacturing based on deep-ultraviolet lithography and electron-beam lithography enables rapid prototyping of PICs,which can be integrated with high-quality PCMs based on the wafer-scale sputtering technique as a back-end-of-line *** this article,we present an overview of recent advances in waveguide integrated PCM memory cells,functional devices,and neuromorphic systems,with an emphasis on fabrication and integration processes to attain state-of-the-art device *** a short overview of PCM based photonic devices,we discuss the materials properties of the functional layer as well as the progress on the light guiding layer,namely,the silicon and germanium waveguide ***,we discuss the cleanroom fabrication flow of waveguide devices integrated with thin films and nanowires,silicon waveguides and plasmonic microheaters for the electrothermal switching of PCMs and mixed-mode ***,the fabrication of photonic and photonic–electronic neuromorphic computing systems is *** systems consist of arrays of PCM memory elements for associative learning,matrix-vector multiplication,and pattern *** large-scale integration,the neuromorphic photonic computing paradigm holds the promise to outperform digital electronic accelerators by taking the advantages of ultra-high bandwidth,high speed,and energy-efficient operation in running machine learning algorithms.

关键词： nanofabrication silicon photonics phase-change materials non-volatile photonic memory neuromorphic photonic computing

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Perfluorinated iodine alkanes promote the differentiation of mouse embryonic stem cells by regulating estrogen receptor signaling

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Journal of Environmental sciences 2024年第3期137卷 443-454页

作者： Zhihua Ren xiaoxi yang Tingting Ku Qian s.Liu Jiefeng Liang Qunfang zhou Francesco Faiola Guibin Jiang state Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China College of Resources and Environment University of Chinese Academy of SciencesBeijing 100049China College of Environment and Resource Research Center of Environment and HealthShanxi UniversityTaiyuan 030006China College of sino-Danish University of Chinese Academy of SciencesBeijing 100049China

Investigating the development toxicity of perfuorinated iodine alkanes(PFIs)is critical,given their estrogenic effects through binding with estrogen receptors(ERs).In the present study,two PFIs,including dodecafuoro-1,6-diiodohexane(PFHx DI)and tridecafuorohexyl iodide(PFHx I),with binding preference to ERαand ERβ,respectively,were selected to evaluate their effects on proliferation and differentiation of the mouse embryonic stem cells(m EsCs).The results revealed that,similar to E_(2),50μmol/L PFHx DI accelerated the cell proliferation of the m *** PFI stimulation at the exposure concentrations of 2–50μmol/L promoted the differentiation of the m EsCs as characterized by the upregulation of differentiation-related biomarkers(i.e.,Otx2 and Dnmt3β)and downregulation of pluripotency genes(i.e.,Oct4,Nanog,sox2,Prdm14 and Rex1).Comparatively,PFHx DI exhibited higher induction effect on the differentiation of the m EsCs than did PFHx *** tests on ER signaling indicated that both PFI compounds induced exposure concentration-dependent expressions of ER signaling-related biomarkers(i.e.,ERα,ERβand Caveolin-1)in the m EsCs,and the downstream ER responsive genes(i.e.,c-fos,c-myc and c-jun)well responded to PFHx I *** role of ER in PFI-induced effects on the m EsCs was further validated by the antagonistic experiments using an ER inhibitor(ICI).The findings demonstrated that PFIs triggered ER signaling,and perturbed the differentiation program of the m EsCs,causing the potential health risk during early stage of development.

关键词： Perfuorinated iodine alkanes(PFIs) Embryonic stem cells(EsCs) Developmental toxicity Cell differentiation Estrogen receptor-related signaling

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2.5-dimension soil seismic response to oblique incident waves based on exact free-field solution

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Frontiers of structural and Civil Engineering 2024年第2期18卷 216-235页

作者： Yeongbin yang Zeyang zhou xiaoli Wang xiongfei Zhang Zhilu Wang school of Civil Engineering Chongqing UniversityChongqing 400045China school of Civil Engineering and Architecture Chongqing University of Science and TechnologyChongqing 401331China

With the three dimensional(3D)oblique incident waves exactly determined for the free field,the soil seismic responses in both frequency and time domains are studied by the 2.5 dimension(2.5D)finite/infinite element ***,the free-field responses in frequency domain are solved exactly for 3D arbitrary incident P and sV waves,which requires no coordinate conversion or extra effort for sV waves with super-critical incident ***,the earthquake spectra are incorporated by the concept of equivalent seismic forces on the near-field boundary,based only on the displacements input derived for unit ground accelerations of each frequency using the 2.5D *** the asymmetric 2.5D finite/infinite element model adopted,the procedure for soil seismic analysis is *** solutions computed by the proposed method are verified against those of Wolf’s and de Barros and Luco’s and for inversely calculated ground *** interest is that abrupt variation in soil response occurs around the critical angle on the wave propagation plane for sV *** addition,the horizontal displacements attenuate with increasing horizontal incident angle,while the longitudinal ones increase inversely for 3D incident P and sV waves.

关键词： 3D oblique incident wave seismic response analysis 2.5D approach infinite element half-space

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Beamline design for multipurpose muon beams at CsNs EMus

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Nuclear science and Techniques 2024年第5期35卷 1-12页

作者： yang Hong Ying-Peng song Lu-Ping zhou Jing-Yu Tang Zhi-Hao zhou Nikolaos Vassilopoulos Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China spallation Neutron source science Center Dongguan 523803China University of Chinese Academy of sciences Beijing 100049China Radiotherapy Physics and Technology Center Cancer CenterWest China HospitalSichuan UniversityChengdu 610041China xi’an Jiaotong University Health science Center Xi’an 710049China Department of Radiation Oncology First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710049China school of Nuclear science and Technology University of Science and Technology of ChinaHefei 230027China

A new muon beam facility,called the Experimental Muon source(EMus),was proposed for construction at the China spallation Neutron source(CsNs).The design of the complex muon beamlines for the EMus baseline scheme,which is based on superconducting solenoids,superferric dipoles and room-temperature magnets,is presented *** muon beams,including surface muons,decay muons and low energy muons,have been developed for multipurpose *** optics design and simulation results of the trunk beamline and branch beamlines are *** a proton beam power of 25 kW at a standalone target station that consists of a conical graphite target and high-field superconducting solenoids,the muon beam intensity in the trunk beamline varies from 10^(7)/s for surface muons to 10^(10)/s for high-momentum decay *** at the endstations,these values vary from 10^(5)/s for surface muons to 10^(8)/s for decay muons.

关键词： surface muons Decay muons Muon beamline superconducting solenoids Multi-channel electrostatic separator

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Tribological behavior of lubricant-impregnated porous polyimide

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Friction 2024年第4期12卷 711-725页

作者： Jinbang LI Ningning zhou Janet s.s.WONG school of Mechanical Engineering and Mechanics Ningbo UniversityNingbo 315211China Beijing Key Laboratory of Long-life Technology of Precise Rotation and Transmission Mechanisms Beijing Institute of Control EngineeringBeijing 100029China Department of Mechanical Engineering Imperial College LondonLondon SW72AZUK

Porous materials impregnated with lubricants can be used in conditions where limited lubricant is *** this work,three porous polyimides(PPI)with different densities were ***(PAO)impregnated PPI(iPPI)discs were rubbed against steel and sapphire *** operando observations of the iPPI-sapphire contacts show that oil is released under an applied load,forming a meniscus around *** at the outlet is created at high sliding *** amount of released oil increases with increasing PPI *** moduli,E*,estimated based on the actual contact size show that trapped oil in iPPIs contributes to load *** higher speeds,tribological rehydration of the contact occurs in low density iPPI,with that E*rises with *** high density PPIs,high speeds give a constantly high E*which is limited by the viscoelastic properties of the PPI network and possibly the rate of oil *** of iPPI-steel contacts is governed by the mechanical properties of the PPI,the flow of the lubricant,and the roughness of the PPI *** low-and medium-density(highly porous,high roughness)PPIs,large amount of oil is released,and lubrication is mainly via lubricant restricted in the contact in the pores and possibly tribological *** high density(low porosity)PPI,with lower roughness,hydrodynamic lubrication is achieved which gives the lowest *** results show that polymeric porous materials for effective lubrication require the optimization of its surface roughness,stiffness,oil flow,and oil retentions.

关键词： polyimide porous material friction mechanism polymer limited lubrication

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