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Tailoring spontaneous infrared emission of HgTe quantum dots with laser-printed plasmonic arrays

Light(science & Applications) 2020年第1期9卷 1870-1879页

作者： A.A.sergeev D.v.Pavlov A.A.Kuchmizhak M.v.Lapine W.K.Yiu Y.Dong N.Ke s.Juodkazis N.Zhao s.v.kershaw A.L.Rogach Institute of Automation and Control Processes Far Eastern BranchRussian Academy of SciencesVladivostok 690041Russia Far Eastern Federal University Vladivostok 690090Russia University of Technology sydney NSW 2007 SydneyAustralia Department of Materials science and Engineering and Centre for Functional Photonics(CFP)City University of Hong KongKowloonHong Kong SARChina Engineering Research Center of Nano-Geomaterials of Ministry of Education Faculty of Material Science and ChemistryChina University of GeosciencesWuhan 430074China Department of Electronic Engineering The Chinese University of Hong KongShatinNew TerritoriesHong Kong SARChina swinburne University of Technology John St.HawthornVIC 3122Australia Melbourne Centre for Nanofabrication ANFF151 Wellington RoadClaytonVIC 3168Australia

Chemically synthesized near-infrared to mid-infrared(IR)colloidal quantum dots(QDs)offer a promising platform for the realization of devices including emitters,detectors,security,and sensor ***,at longer wavelengths,the quantum yield of such QDs decreases as the radiative emission rate drops following Fermi’s golden rule,while non-radiative recombination channels compete with light *** over the radiative and non-radiative channels of the IR-emitting QDs is crucially important to improve the performance of IR-range ***,we demonstrate strong enhancement of the spontaneous emission rate of near-to mid-IR HgTe QDs coupled to periodically arranged plasmonic nanoantennas,in the form of nanobumps,produced on the surface of glasssupported Au films via ablation-free direct femtosecond laser *** enhancement is achieved by simultaneous radiative coupling of the emission that spectrally matches the first-order lattice resonance of the arrays,as well as more efficient photoluminescence excitation provided by coupling of the pump radiation to the local surface plasmon resonances of the isolated ***,coupling of the HgTe QDs to the lattice plasmons reduces the influence of non-radiative decay losses mediated by the formation of polarons formed between QD surface-trapped carriers and the IR absorption bands of dodecanethiol used as a ligand on the QDs,allowing us to improve the shape of the emission spectrum through a reduction in the spectral dip related to this ligand *** the ease of the chemical synthesis and processing of the HgTe QDs combined with the scalability of the direct laser fabrication of nanoantennas with tailored plasmonic responses,our results provide an important step towards the design of IR-range devices for various applications.

关键词： quantum radiative coupling

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semantic segmentation of Lumbar vertebrae Using Meijering U-Net(MU-Net)on spine Magnetic Resonance Images

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Computer Modeling in Engineering & sciences 2025年第1期142卷 733-757页

作者： Lakshmi s v v shiloah Elizabeth Darmanayagam sunil Retmin Raj Cyril Department of Computer science and Engineering College of Engineering GuindyAnna UniversityChennai600025India Department of Information Technology Madras Institute of TechnologyAnna UniversityChrompetChennai600044India

Lower back pain is one of the most common medical problems in the world and it is experienced by a huge percentage of people *** to its ability to produce a detailed view of the soft tissues,including the spinal cord,nerves,intervertebral discs,and vertebrae,Magnetic Resonance Imaging is thought to be the most effective method for imaging the *** semantic segmentation of vertebrae plays a major role in the diagnostic process of lumbar *** is difficult to semantically partition the vertebrae in Magnetic Resonance Images from the surrounding variety of tissues,including muscles,ligaments,and intervertebral discs.U-Net is a powerful deep-learning architecture to handle the challenges of medical image analysis tasks and achieves high segmentation *** work proposes a modified U-Net architecture namely MU-Net,consisting of the Meijering convolutional layer that incorporates the Meijering filter to perform the semantic segmentation of lumbar vertebrae L1 to L5 and sacral vertebra ***-colour mask images were generated and used as ground truth for training the *** work has been carried out on 1312 images expanded from T1-weighted mid-sagittal MRI images of 515 patients in the Lumbar spine MRI Dataset publicly available from Mendeley *** proposed MU-Net model for the semantic segmentation of the lumbar vertebrae gives better performance with 98.79%of pixel accuracy(PA),98.66%of dice similarity coefficient(DsC),97.36%of Jaccard coefficient,and 92.55%mean Intersection over Union(mean IoU)metrics using the mentioned dataset.

关键词： Computer aided diagnosis(CAD) magnetic resonance imaging(MRI) semantic segmentation lumbar vertebrae deep learning U-Net model

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Unlocking hypoglycemia–associated brain microvascular dysfunction:critical insights from proteomic analysis

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Neural Regeneration Research 2025年第6期20卷 1707-1708页

作者： siva s.v.P.sakamuri Anil sakamuri Department of Chemistry Auburn University at MontgomeryMontgomeryALUSA vascular Biology Center and Department of Medicine Medical College of Georgia at Augusta UniversityAugustaGAUSA

Hypoglycemia-a critical complication linked to worsened brain function in diabetic subjects:Hypoglycemia is characterized by a decline in circulatory glucose levels below sta nda rd physiological *** hypoglycemia,classified as level 1 hypoglycemia,is defined by blood glucose levels below 70 mg/dL and can be effectively addressed through carbohydrate *** hypoglycemia,denoted by blood glucose levels less than 54 mg/dL,poses a life-threatening risk if left *** with type 1 and type 2 diabetes undergoing insulin treatment are particularly susceptible to hypoglycemia due to impaired counterregulatory mechanisms.

关键词： impaired intake critical

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A comprehensive investigation on nonlinear vibration and bending characteristics of bio-inspired helicoidal laminated composite structures

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 81-100页

作者： s.sAURABH R.KIRAN D.sINGH R.vAIsH v.s.CHAUHAN school of Mechanical and Materials Engineering Indian Institute of Technology Mandi

Bio-inspired helicoidal composite laminates, inspired by the intricate helical structures found in nature, present a promising frontier for enhancing the mechanical properties of structural designs. Hence, this study provides a comprehensive investigation into the nonlinear free vibration and nonlinear bending behavior of bio-inspired composite plates. The inverse hyperbolic shear deformation theory(IHsDT) of plates is employed to characterize the displacement field, with the incorporation of Green-Lagrange nonlinearity. The problem is modeled using the C0finite element method(FEM), and an in-house code is developed in the MATLAB environment to solve it numerically. various helicoidal layup configurations including helicoidal recursive(HR), helicoidal exponential(HE), helicoidal semi-circular(Hs), linear helicoidal(LH), and Fibonacci helicoidal(FH)with different layup sequences and quasi-isotropic configurations are studied. The model is validated, and parametric studies are conducted. These studies investigate the effects of layup configurations, side-to-thickness ratio, modulus ratios, boundary conditions, and loading conditions at different load amplitudes on the nonlinear vibration and nonlinear bending behaviors of bio-inspired composite plates. The results show that the laminate sequence exerts a substantial impact on both nonlinear natural frequencies and nonlinear bending behaviors. Moreover, this influence varies across different side-to-thickness ratios and boundary conditions of the bio-inspired composite plate.

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An sPH Framework for Earthquake-Induced Liquefaction Hazard Assessment of Geotechnical structures

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Computer Modeling in Engineering & sciences 2025年第1期142卷 251-277页

作者： sourabh Mhaski G.v.Ramana Department of Civil Engineering Indian Institute of Technology DelhiNew Delhi110016India

Earthquake-induced soil liquefaction poses significant risks to the stability of geotechnical structures *** understanding of the liquefaction triggering,and the post-failure large deformation behaviour is essential for designing resilient *** present study develops a smoothed Particle Hydrodynamics(sPH)framework for earthquake-induced liquefaction hazard assessment of geotechnical *** coupled flowdeformation behaviour of soils subjected to cyclic loading is described using the PM4sand model implemented in a three-phase,single-layer sPH framework.A staggered discretisation scheme based on the stress particle sPH approach is adopted to minimise numerical inaccuracies caused by zero-energy modes and tensile ***,non-reflecting boundary conditions for seismic analysis of semi-infinite soil domains using the sPH method are *** numerical framework is employed for the analysis of cyclic direct simple shear test,seismic analysis of a level ground site,and liquefaction-induced failure of the Lower san Fernando *** agreement for liquefaction triggering and post-failure behaviour demonstrates that the sPH framework can be utilised to assess the effect of seismic loading on field-scale geotechnical *** present study also serves as the basis for future advancements of the sPH method for applications related to earthquake geotechnical engineering.

关键词： Earthquake seismic liquefaction stress particle PM4sand smoothed particle hydrodynamics(sPH)

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Brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

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Neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tomàs víctor Cilleros-Mañé Laia Just-Borràs Marta Balanyà-segura Aleksandra Polishchuk Laura Nadal Marta Tomàs Carolina silvera-simón Manel M.santafé Maria A.Lanuza Unitat d’Histologia i Neurobiologia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase B receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results based on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and C(PKA and PKC)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated TrkB/p75NTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PKA/PKC activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the N-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorB

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Palaeogeographic variation in the Permian-Triassic boundary microbialites:A discussion of microbial and ocean process esafter the end-Permian mass extinction

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Journal of Palaeogeography 2017年第2期6卷 97-107页

作者： stephen kershaw Department of Life sciences Brunel University Kingston Lane Uxbridge UB8 3PH UK

shallow marine carbonate sediments that formed after the end-Permian mass extinction are rich in a thin(maximum ca.15 m) deposit of *** communities that constructed the microbialites have geographic variability of composition,broadly divisible into two groups:1) eastern Tethys sites are calcimicrobe-dominated(appearing as thrombolites in the field),with rare occurrence of sedimentconstructed microbialites and uncommon cements either within microbial structure or as inorganic precipitates,2) other Tethys sites are sediment-dominated structures forming stromatolites and thrombolites,composed of micrites and cements,with some inorganic *** other Tethys locations include western and central Tethys sites but their palaeogeographic positions depend on the accuracy of continental reconstructions,of which there are several *** contrast to geographic variation of microbialites,the conodont Hindeodus parvus,which appeared after the extinction and defines the base of the Triassic,is widespread,indicating easy lateral migration throughout *** animals were active nekton,although being small animals were presumably at least partly carried by water currents,implying active Tethyan surface water circulation after the extinction ***-extinction ammonoid taxa,presumed active swimmers,show poor evidence of a wide distribution in the Griesbachian beds immediately after the extinction,but are more cosmopolitan higher up,in the Dienerian strata in *** shelly fossils also have poorly defined distributions after the extinction,but ostracods show some wider distribution suggesting migration was possible after the *** there is a contrast between the geographic differences of microbialites and some shelly *** the cause of geographic variation of post-extinction microbialites is problematic and may include one or more of the following possibilities:1) because calcifying microbial organisms th

关键词： stromatolite Thrombolite Microbialite Permian-Triassic boundary Conodonts Tethys Mass extinction

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Modern Black sea oceanography applied to the end-Permian extinction event

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Journal of Palaeogeography 2015年第1期4卷 52-62页

作者： steve kershaw Institute for the Environment Health and Societies Brunel UniversityKingston LaneUxbridge Middlesex UB8 3PH UK

The modern Black sea has a mixed upper layer in the top 150-200 m of the water column, below which the water is anoxic, separated from the mixed layer by a redox boundary. There is limited vertical movement of water. Pyrite framboids form in the water column of the anoxic zone, then have been traditionally interpreted to sink immediately and accumulate in the sediments of the Black sea. Thus the occurrence of framboids in sediments in the rock record is widely interpreted to indicate poorly oxygenated to anoxic conditions in ancient environments. However, in the Permian-Triassic boundary （PTB） microbialites of south China, which formed in shallow marine conditions in contact with the atmosphere, the published occurrence of framboids is inconsistent with abundant gastropod and ostracod shells in the microbialite. Furthermore, in the modern Black sea, （a） framboids may be suspended, attached to organic matter in the water column, thus not settle to the sea floor immediately after formation; and （b） the redox zone is an unstable complex area subject to rapid vertical water movement including occasional upwelling. The model presented here supposes that upwelling through the redox zone can lead to upward transport of suspended pyrite framboids into the mixed layer. Advective circulation could then draw suspended framboids onto the shelf to be deposited in oxygenated sediments. In the Permian-Triassic transition, if framboids were upwelled from below the redox boundary and mixed with oxygenated waters, sediment deposited in these conditions could provide a mixed signal for potentially misleading interpretations of low oxygen conditions. However, stratigraphic sampling resolution of post-extinction microbialites is currently insufficient to demonstrate possible separation of framboid-bearing layers from those where framboids are absent. Profound differences between microbialite constructors and sequences between the western and eastern Tethys demonstrate barriers to migra

关键词： mass extinction Permian-Triassic boundary microbialite ostracods gastro-pods anoxia Black sea

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Autism spectrum disorder:difficulties in diagnosis and microRNA biomarkers

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Neural Regeneration Research 2025年第10期20卷 2776-2786页

作者： Bridget Martinez Philip v.Peplow Department of Pharmacology University of Nevada-RenoRenoNVUSA Department of Medicine University of Nevada-RenoRenoNVUSA Department of Anatomy University of OtagoDunedinNew Zealand

We performed a PubMed search for microRNAs in autism spectrum disorder that could serve as diagnostic biomarkers in patients and selected 17 articles published from January 2008 to December 2023,of which 4 studies were performed with whole blood,4 with blood plasma,5 with blood serum,1 with serum neural cell adhesion molecule L1-captured extracellular vesicles,1 with blood cells,and 2 with peripheral blood mononuclear *** of the studies involved children and the study cohorts were largely *** of the studies had performed microRNA sequencing or quantitative polymerase chain reaction assays to measure microRNA *** five studies had used real-time polymerase chain reaction assay to validate microRNA expression in autism spectrum disorder subjects compared to *** microRNAs that were validated in these studies may be considered as potential candidate biomarkers for autism spectrum disorder and include miR-500a-5p,-197-5p,-424-5p,-664a-3p,-365a-3p,-619-5p,-664a-3p,-3135a,-328-3p,and-500a-5p in blood plasma and miR-151a-3p,-181b-5p,-320a,-328,-433,-489,-572,-663a,-101-3p,-106b-5p,-19b-3p,-195-5p,and-130a-3p in blood serum of children,and miR-15b-5p and-6126 in whole blood of *** important limitations were identified in the studies reviewed,and need to be taken into account in future *** studies are warranted with children and adults having different levels of autism spectrum disorder severity and consideration should be given to using animal models of autism spectrum disorder to investigate the effects of suppressing or overexpressing specific microRNAs as a novel therapy.

关键词： autism spectrum disorder biomarker blood cells blood plasma blood serum diagnosis microRNA peripheral blood mononuclear cells serum neural cell adhesion molecule L1-captured extracellular vesicles whole blood

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MicroRNAs as potential diagnostic biomarkers for bipolar disorder

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Neural Regeneration Research 2025年第6期20卷 1681-1695页

Abnormal expression of microRNAs is connected to brain development and disease and could provide novel biomarkers for the diagnosis and prognosis of bipolar disorder. We performed a PubMed search for microRNA biomarkers in bipolar disorder and found 18 original research articles on studies performed with human patients and published from January 2011 to June 2023. These studies included microRNA profiling in bloodand brain-based materials. From the studies that had validated the preliminary findings,potential candidate biomarkers for bipolar disorder in adults could be miR-140-3p,-30d-5p,-330-5p,-378a-5p,-21-3p,-330-3p,-345-5p in whole blood, miR-19b-3p,-1180-3p,-125a-5p, let-7e-5p in blood plasma, and miR-7-5p,-23b-5p,-142-3p,-221-5p,-370-3p in the blood serum. Two of the studies had investigated the changes in microRNA expression of patients with bipolar disorder receiving treatment. One showed a significant increase in plasma miR-134 compared to baseline after 4 weeks of treatment which included typical antipsychotics, atypical antipsychotics, and benzodiazepines. The other study had assessed the effects of prescribed medications which included neurotransmitter receptorsite binders(drug class B) and sedatives, hypnotics, anticonvulsants, and analgesics(drug class C) on microRNA results. The combined effects of the two drug classes increased the significance of the results for miR-219 and-29c with miR-30e-3p and-526b* acquiring significance. MicroRNAs were tested to see if they could serve as biomarkers of bipolar disorder at different clinical states of mania, depression, and euthymia. One study showed that upregulation in whole blood of miR-9-5p,-29a-3p,-106a-5p,-106b-5p,-107,-125a-3p,-125b-5p and of miR-107,-125a-3p occurred in manic and euthymic patients compared to controls, respectively, and that upregulation of miR-106a-5p,-107 was found for manic compared to euthymic patients. In two other studies using blood plasma,downregulation of miR-134 was observed i

关键词： biomarker bipolar disorder blood leukocytes blood plasma blood plasma extracellular vesicles/exosomes blood serum brain tissue brain tissue extracellular vesicles/exosomes lymphoblastoid cell lines microRNA neural progenitor cells whole blood

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