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Dispersal behavior of yellowjacket （Vespula germanica） queens

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Insect science 2018年第1期25卷 109-116页

作者： Maite Masciocchi Andres s. Martinez Aria j. Pereira jose M. Villacide juan C. Corley CONICET CCT Comahue INTA Grupo de Ecologia de Poblaciones de Insectos INTA EEA Bariloche Argentina Centro Regional Universitario Bariloche U. N. del Comahue Bariloche 8400 Argentina

Understanding the factors that affect animal dispersal behavior is important from both *** and applied perspectives. Dispersal can have clear evolutionary and ecological consequences, but for normative insect pests, dispersal capacity can also help to explain invasion success. Vespula germanica is a social wasp that, in the last century, has successfully invaded several regions of the world, showing one of the highest spread rates reported for a nonnative insect. In contrast with nonsocial wasps, in social species, queens are responsible for population redistribution and spread, as workers are sterile. For V. germanica, it has been observed that queen flight is limited to 2 distinct periods： early autumn, when new queens leave the nest to mate and find sheltered places in which to hibernate, and spring when new colonies are founded. Our aim was to study the flight behavior of V. germanica queens by focusing on the different periods in which dispersal occurs, characterizing as well the potential contribution of queen flight （i.e., distance） to the observed geographical spread. Our results suggest that the distances flown by nonover- wintered queens is greater than that flown by overwintered individuals, suggesting that the main queen dispersal events would occur before queens enter hibernation. This could relate to a behavioral trait of the queens to avoid the inbreeding with related drones. Additionally, given the short distances flown and remarkable geographical spread observed, we provide evidence showing that queen dispersal by flight is likely to contribute proportionately less to population spread than human-aided factors.

关键词： flight potential German wasps hibernation invasive wasps social insect

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结核病患者氧氟沙星的群体药代动力学

国际结核病与肺部疾病杂志 2002年第4期 152-157页

作者： M.Zhu j.j.stambaugh s.E.Berning A.E.Bulpitt E.s.Hollender M.Narita D.Ashkin C.A.Peloquin 马玙 Department of Medicine National Jewish Medical and Research Center Denver Colorado Drug Metabolism and Pharmacokinetics Schering-Plough Research Institute Kenilworth New Jersey AG Holley state Hospital Lantana Florida Department of Medicine National Jewish Medical and Research Center Denver Colorado School of Pharmacy University of Colorado Denver Colorado Department of Medicine National Jewish Medical and Research Center Denver Colorado AG Holley state Hospital Lantana Florida School of Pharmacy University of Colorado Denver Colorado Division of Pulmonary and Critical Care Medicine University of Miami School of Medicine Miami Bureau of Tuberculosis and Refugee Health Florida Department of Health Miami Florida Department of Medicine National Jewish Medical and Research Center Denver Colorado School of Pharmacy University of Colorado Denver Colorado School of Medicine University of Colorado Denver Colorado USA

背景:美国两所结核病医院。目的:测定口服多种剂量氧氟沙星后的群体药代动力学(PK)。设计:共73例结核病患者参加本研究,其中一部分患者接受多种剂量的氧氟沙星。根据药敏结果,同时服用其它药物。收集10小时以上的血清样本经高压液相... 详细信息

背景:美国两所结核病医院。目的:测定口服多种剂量氧氟沙星后的群体药代动力学(PK)。设计:共73例结核病患者参加本研究,其中一部分患者接受多种剂量的氧氟沙星。根据药敏结果,同时服用其它药物。收集10小时以上的血清样本经高压液相色谱仪测定,采用群体方法分析浓度-时间数据。结果:氧氟沙星浓度随增加的口服剂量呈线形上升。29％患者至少有一次吸收延缓。氧氟沙星清除随肾功能下降和年龄增加而降低。患者对较高剂量耐受良好,且可最大限度提高血药峰值浓度与最低抑菌浓度之比值(Cmax:MIC)。结论:氧氟沙星群体药代动力学参数与以往报告结果相似。较高剂量可具有良好的药代动力学,有利于结核病的治疗。

关键词：氧氟沙星结核病药代动力学

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聚氨酯血管植入装置用于基因治疗的动物实验

中国医学科学院学报 2006年第5期28卷 682-685,I0003页

作者：宋存先张琳华杨菁 stanley j.stachelek Robert j.Levy 中国医学科学院中国协和医科大学生物医学工程研究所天津生物医学材料重点实验室 Division of Cardiology Children s Hospital of Philadelphia PA 19104 USA

目的利用可植入体内的经过修饰的功能化聚氨酯构建两种血管内植入装置,分别植入猪肾下腹主动脉和羊肺中进行基因转染实验,研究其作为基因运载平台的可行性。方法将涂覆胶原的聚氨酯膜通过抗体免疫偶联编码绿色荧光蛋白的腺病毒(AdGFP)... 详细信息

目的利用可植入体内的经过修饰的功能化聚氨酯构建两种血管内植入装置,分别植入猪肾下腹主动脉和羊肺中进行基因转染实验,研究其作为基因运载平台的可行性。方法将涂覆胶原的聚氨酯膜通过抗体免疫偶联编码绿色荧光蛋白的腺病毒(AdGFP)制备成聚氨酯-胶原膜埋植钮装置并植入猪肾下腹主动脉中,7d后取出埋植钮及其周围组织进行切片、荧光显微镜检测及PCR分析;将抗腺病毒抗体直接通过共价连接在带有硫醇化烷基的功能化聚氨酯膜上实现与AdGFP的免疫偶联,制备成聚氨酯人工瓣膜并植入羊肺中,7d后取出肺部小叶及其周围组织进行荧光显微镜检测及PCR分析。结果在猪体内实验中,植入体表面的新生内膜细胞基因转染率为(14.2±2.5)%;在羊体内实验中,聚氨酯瓣膜小叶上的细胞有(25.1±5.7)%被转染。PCR结果显示,在血液或末端组织中都未检测到GFPDNA。结论这两种血管内聚氨酯基因载运系统能够作为靶向高效载运腺病毒的载体,用于心血管疾病的基因治疗。

关键词：功能化聚氨酯埋植钮人工瓣膜基因治疗

Evaluation of greenhouse gas emission reduction potential of a demand–response solution:a carbon handprint case study of a virtual power plant

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Clean Energy 2023年第4期7卷 755-766页

作者： j.sillman L.Lakanen s.Annala K.Gronman M.Luoranen R.soukka LUT University School of Energy SystemsSustainability SciencePO Box 2053851 LappeenrantaFinland

The transition towards zero-carbon energy production is necessary to limit global *** energy systems have facilitated the control of demand-side resources to maintain the stability of the power grid and to provide balancing power for increasing renewable energy *** power plants are examples of demand–response solutions,which may also enable greenhouse gas(GHG)emission reductions due to the lower need for fossil-based balancing energy in the grid and the increased share of *** aim of this study is to show how potential GHG emission reductions can be assessed through the carbon handprint approach for a virtual power plant(VPP)in a grid balancing market in *** to our results,VPP can reduce the hourly based GHG emissions in the studied Finnish grid systems compared with the balancing power without the *** energy sources used for the balance power are hydropower and fossil *** reduction potential of GHG emissions varies from 68%to 98%depending on the share of the used energy source for the power balancing,thus VPPs have the potential to significantly reduce GHG emissions of electricity production and hence help mitigate climate change.

关键词： virtual power plant demand–response carbon handprint greenhouse gas emissions electric grid

Tracking the Cretaceous transcontinental Ceduna River through Australia:The hafnium isotope record of detrital zircons from offshore southern Australia

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Geoscience Frontiers 2016年第2期7卷 237-244页

作者： jarred Lloyd Alan s.Collins.j.stin L.Payne stijn Glorie simon Holford Anthony j.Reid Centre for Tectonics Resources and Exploration(TRaX)Department of Earth SciencesThe University of Adelaide Centre for Tectonics Resources and Exploration(TRaX)School of Built and Natural EnvironmentsThe University of South Australia Centre for Tectonics Resources and Exploration(TRaX)Australian School of PetroleumThe University of Adelaide Geological survey of south Australia Department of State DevelopmentGovernment of South Australia

The middle-upper Cretaceous Ceduna River system traversed continental Australia from the NE coast to the centre of the southern coast. At its mouth, it formed a vast delta system that is similar in scale to the Niger delta of West Africa. The delta system is composed of two main lobes that represent different phases of delta construction. A recent hypothesis has challenged the traditional idea that both lobes of the delta were derived from a transcontinental river system by suggesting that the upper lobe （santonian -Maastrichtian） is instead derived from a restricted catchment within southern Australia. Hf isotopic data presented here fingerprint the original source of the upper delta lobe zircons to NE Australia, with data comparing well with similar U-Pb and Lu-Hf isotopic data from the Lachlan Orogen, the New England Orogen, the eastern Musgraves Province and the northern Flinders Ranges. These data do not preclude a model where the lobe is derived from recycled Eromanga Basin sediments during a phase of late Cretaceous inland Australian uplift, but when coupled with reconnaissance low-temperature thermochronometry from the region of the Ceduna River course indicating widespread Triassic-jurassic exhumation, and comparisons with detrital zircon data from the Winton Formation upstream of any proposed uplift, we suggest that both lobes of the Ceduna Delta are likely to be derived from a transcontinental Ceduna River.

关键词： Detrital zircon Hf U-Pb Ceduna sub-basin Bight basin Australia

Hydrogen for a Net-Zero Carbon World

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Engineering 2023年第10期29卷 8-10页

作者： Nigel P.Brandon james.j.Brandon Faculty of Engineering Imperial College LondonSouth Kensington CampusLondon SW72AZUK The First Element Ltd. London N17GUUK

*** hydrogen?The concept of the“hydrogen economy”was first coined by *** Bockris during a talk he gave in 1970 at the General Motors Technical ***’s talk introduced the vision of a world economy in which energy was... 详细信息

关键词： hydrogen Carbon economy

Prograde and retrograde growth of monazite in migmatites:An example from the Nagercoil Block,southern India

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Geoscience Frontiers 2015年第3期6卷 373-387页

作者： Tim E.johnson Chris Clark Richard j.M.Taylor M.santosh Alan s.Collins Department of Applied Geology The Institute for Geoscience Research(TIGeR)Curtin University school of the Earth sciences and Resources China University of Geosciences(Beijing) Tectonics Resources and Exploration(TRaX)Department of Earth SciencesUniversity of Adelaide

Data from a migmatised metapelite raft enclosed within charnockite provide quantitative constraints on the pressure-temperature-time （P-T-t） evolution of the Nagercoil Block at the southernmost tip of peninsular India. An inferred peak metamorphic assemblage of garnet, K-feldspar, sillimanite, plagioclase, magnetite, ilmenite, spinel and melt is consistent with peak metamorphic pressures of 6-8 kbar and temperatures in excess of 900 ℃. subsequent growth of cordierite and biotite record high-temperature retrograde decompression to around 5 kbar and 800 ℃. sHRIMP U-Pb dating of magmatic zircon cores suggests that the sedimentary protoliths were in part derived from felsic igneous rocks with Palae- oproterozoic crystallisation ages. New growth of metamorphic zircon on the rims of detrital grains constrains the onset of melt crystallisation, and the minimum age of the metamorphic peak, to around 560 Ma. The data suggest two stages of monazite growth. The first generation of REE-enriched monazite grew during partial melting along the prograde path at around 570 Ma via the incongruent breakdown of apatite. Relatively REE-depleted rims, which have a pronounced negative europium anomaly, grew during melt crystallisation along the retrograde path at around 535 Ma. Our data show the rocks remained at suprasolidus temperatures for at least 35 million years and probably much longer, supporting a long-lived high-grade metamorphic history. The metamorphic conditions, timing and duration of the implied clockwise P-T-t path are similar to that previously established for other regions in peninsular India during the Ediacaran to Cambrian assembly of that part of the Gondwanan supercontinent.

关键词： Monazire Migmatite Zircon Geochronology Phase equilibria modelling Gondwana

以MRI质子密度脂肪分数为参考标准对疑似NAFLD病人进行肝脂肪定量超声与受控衰减参数的直接比较

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国际医学放射学杂志 2022年第5期45卷 600-601页

作者： j.jung A.Han E.Madamba R.Bettencourt R.R.Loomba A.s.Boehringer 姚峄杉李畅

摘要 MRI衍生的质子密度脂肪分数（PDFF）是一种准确、可靠、安全的生物标志物，可用于非酒精性脂肪性肝病（NAFLD）病人肝脂肪变性的无创诊断。由于MRI的成本和

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MRI评估直肠癌新辅助治疗后缓解：一项多位阅片者的研究

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国际医学放射学杂志 2023年第5期 627-628页

作者： j.B.Yuval s.Patil N.Gangai D.M.Omer D.G.Akselrod A.Fung 高博聪

摘要目的以保肛为目标的直肠癌新辅助治疗后“进一步观察”策略是一种新兴治疗方法，但选择合适病人仍具有挑战性。既往大多数采用MRI评估直肠癌治疗反应准确性

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